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1. Goud, GN; Artsaenko, O; Bols, M; Sierks, M
   Specific glycosidase activity isolated from a random phage display antibody library
   BIOTECHNOLOGY PROGRESS
   
   G.N. Goud et al., "Specific glycosidase activity isolated from a random phage display antibody library", BIOTECH PR, 17(1), 2001, pp. 197-202
2. Haberli, A; Leumann, CJ
   Synthesis of pyrrolidine C-nucleosides via heck reaction
   ORGANIC LETTERS
   
   A. Haberli e C.J. Leumann, "Synthesis of pyrrolidine C-nucleosides via heck reaction", ORG LETT, 3(3), 2001, pp. 489-492
3. Kangas, E; Tidor, B
   Electrostatic complementarity at ligand binding sites: Application to chorismate mutase
   JOURNAL OF PHYSICAL CHEMISTRY B
   
   E. Kangas e B. Tidor, "Electrostatic complementarity at ligand binding sites: Application to chorismate mutase", J PHYS CH B, 105(4), 2001, pp. 880-888
4. Sokalski, WA; Kedzierski, P; Grembecka, J
   Ab initio study of the physical nature of interactions between enzyme active site fragments in vacuo
   PHYSICAL CHEMISTRY CHEMICAL PHYSICS
   
   W.A. Sokalski et al., "Ab initio study of the physical nature of interactions between enzyme active site fragments in vacuo", PHYS CHEM P, 3(5), 2001, pp. 657-663
5. Taylor, SV; Kast, P; Hilvert, D
   Investigating and engineering enzymes by genetic selection
   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
   
   S.V. Taylor et al., "Investigating and engineering enzymes by genetic selection", ANGEW CHEM, 40(18), 2001, pp. 3311-3335
6. Bruggemann, O
   Catalytically active polymers obtained by molecular imprinting and their application in chemical reaction engineering
   BIOMOLECULAR ENGINEERING
   
   O. Bruggemann, "Catalytically active polymers obtained by molecular imprinting and their application in chemical reaction engineering", BIOMOL ENG, 18(1), 2001, pp. 1-7
7. Helmstaedt, K; Krappmann, S; Braus, GH
   Allosteric regulation of catalytic activity: Escherichia coli aspartate transcarbamoylase versus yeast chorismate mutase
   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
   
   K. Helmstaedt et al., "Allosteric regulation of catalytic activity: Escherichia coli aspartate transcarbamoylase versus yeast chorismate mutase", MICRO M B R, 65(3), 2001, pp. 404
8. Zhan, CG; Landry, DW
   Theoretical studies of competing reaction pathways and energy barriers foralkaline ester hydrolysis of cocaine
   JOURNAL OF PHYSICAL CHEMISTRY A
   
   C.G. Zhan e D.W. Landry, "Theoretical studies of competing reaction pathways and energy barriers foralkaline ester hydrolysis of cocaine", J PHYS CH A, 105(8), 2001, pp. 1296-1301
9. Takahashi, N; Kakinuma, H; Liu, LD; Nishi, Y; Fujii, I
   In vitro abzyme evolution to optimize antibody recognition for catalysis
   NATURE BIOTECHNOLOGY
   
   N. Takahashi et al., "In vitro abzyme evolution to optimize antibody recognition for catalysis", NAT BIOTECH, 19(6), 2001, pp. 563-567
10. Tondi, D; Powers, RA; Caselli, E; Negri, MC; Blazquez, J; Costi, MP; Shoichet, BK
    Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase
    CHEMISTRY & BIOLOGY
    
    D. Tondi et al., "Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase", CHEM BIOL, 8(6), 2001, pp. 593-610
11. Caselli, E; Powers, RA; Blasczcak, LC; Wu, CYE; Prati, F; Shoichet, BK
    Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases
    CHEMISTRY & BIOLOGY
    
    E. Caselli et al., "Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases", CHEM BIOL, 8(1), 2001, pp. 17-31
12. Wurtele, M; Wolf, E; Pederson, KJ; Buchwald, G; Ahmadian, MR; Barbieri, JT; Wittinghofer, A
    How the Pseudomonas aeruginosa ExoS toxin downregulates Rac
    NATURE STRUCTURAL BIOLOGY
    
    M. Wurtele et al., "How the Pseudomonas aeruginosa ExoS toxin downregulates Rac", NAT ST BIOL, 8(1), 2001, pp. 23-26
13. Dosselaere, F; Vanderleyden, J
    A metabolic node in action: Chorismate-utilizing enzymes in microorganisms
    CRITICAL REVIEWS IN MICROBIOLOGY
    
    F. Dosselaere e J. Vanderleyden, "A metabolic node in action: Chorismate-utilizing enzymes in microorganisms", CR R MICROB, 27(2), 2001, pp. 75-131
14. Kim, JM; Ahn, KD; Wulff, G
    Cholesterol esterase activity of a molecularly imprinted polymer
    MACROMOLECULAR CHEMISTRY AND PHYSICS
    
    J.M. Kim et al., "Cholesterol esterase activity of a molecularly imprinted polymer", MACRO CH P, 202(7), 2001, pp. 1105-1108
15. Biffis, A; Graham, NB; Siedlaczek, G; Stalberg, S; Wulff, G
    The synthesis, characterization and molecular recognition properties of imprinted microgels
    MACROMOLECULAR CHEMISTRY AND PHYSICS
    
    A. Biffis et al., "The synthesis, characterization and molecular recognition properties of imprinted microgels", MACRO CH P, 202(1), 2001, pp. 163-171
16. Kumar, S; Pearson, AL; Pratt, RF
    Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors
    BIOORGANIC & MEDICINAL CHEMISTRY
    
    S. Kumar et al., "Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors", BIO MED CH, 9(8), 2001, pp. 2035-2044
17. Auld, DS
    Zinc coordination sphere in biochemical zinc sites
    BIOMETALS
    
    D.S. Auld, "Zinc coordination sphere in biochemical zinc sites", BIOMETALS, 14(3-4), 2001, pp. 271-313
18. Pasternak, A; White, A; Jeffery, CJ; Medina, N; Cahoon, M; Ringe, D; Hedstrom, L
    The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity
    PROTEIN SCIENCE
    
    A. Pasternak et al., "The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity", PROTEIN SCI, 10(7), 2001, pp. 1331-1342
19. Andreeva, NS; Rumsh, LD
    Analysis of crystal structures of aspartic proteinases: On the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymes
    PROTEIN SCIENCE
    
    N.S. Andreeva e L.D. Rumsh, "Analysis of crystal structures of aspartic proteinases: On the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymes", PROTEIN SCI, 10(12), 2001, pp. 2439-2450
20. Kato-Toma, Y; Ishiguro, M
    Reaction of Lys-Tyr-Lys triad mimics with benzylpenicillin: Insight into the role of Tyr150 in class C beta-lactamase
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    Y. Kato-Toma e M. Ishiguro, "Reaction of Lys-Tyr-Lys triad mimics with benzylpenicillin: Insight into the role of Tyr150 in class C beta-lactamase", BIOORG MED, 11(9), 2001, pp. 1161-1164
21. Tsumuraya, T; Takazawa, N; Tsunakawa, A; Fleck, R; Masamune, S
    Catalytic antibodies induced by a zwitterionic hapten
    CHEMISTRY-A EUROPEAN JOURNAL
    
    T. Tsumuraya et al., "Catalytic antibodies induced by a zwitterionic hapten", CHEM-EUR J, 7(17), 2001, pp. 3748-3755
22. Steiner, RA; Rozeboom, HJ; de Vries, A; Kalk, KH; Murshudov, GN; Wilson, KS; Dijkstra, BW
    X-ray structure of bovine pancreatic phospholipase A(2) at atomic resolution
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    
    R.A. Steiner et al., "X-ray structure of bovine pancreatic phospholipase A(2) at atomic resolution", ACT CRYST D, 57, 2001, pp. 516-526
23. Wouters, J; Charlier, P; Monnaie, D; Frere, JM; Fonze, E
    Expression, purification, crystallization and preliminary X-ray analysis of the native class C beta-lactamase from Enterobacter cloacae 908R and two mutants
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    
    J. Wouters et al., "Expression, purification, crystallization and preliminary X-ray analysis of the native class C beta-lactamase from Enterobacter cloacae 908R and two mutants", ACT CRYST D, 57, 2001, pp. 162-164
24. Gilboa, R; Spungin-Bialik, A; Wohlfahrt, G; Schomburg, D; Blumberg, S; Shoham, G
    Interactions of Streptomyces griseus aminopeptidase with amino acid reaction products and their implications toward a catalytic mechanism
    PROTEINS-STRUCTURE FUNCTION AND GENETICS
    
    R. Gilboa et al., "Interactions of Streptomyces griseus aminopeptidase with amino acid reaction products and their implications toward a catalytic mechanism", PROTEINS, 44(4), 2001, pp. 490-504
25. Kuhlmann, J; Herrmann, C
    Biophysical characterization of the Ras protein
    BIOORGANIC CHEMISTRY OF BIOLOGICAL SIGNAL TRANSDUCTION
    
    J. Kuhlmann e C. Herrmann, "Biophysical characterization of the Ras protein", T CURR CHEM, 211, 2001, pp. 61-116
26. Bernard, P; Pintore, M; Berthon, JY; Chretien, JR
    A molecular modeling and 3D QSAR study of a large series of indole inhibitors of human non-pancreatic secretory phospholipase A(2)
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    
    P. Bernard et al., "A molecular modeling and 3D QSAR study of a large series of indole inhibitors of human non-pancreatic secretory phospholipase A(2)", EUR J MED C, 36(1), 2001, pp. 1-19
27. Mardanyan, S; Sharoyan, S; Antonyan, A; Armenyan, A; Cristalli, G; Lupidi, G
    Tryptophan environment in adenosine deaminase I. Enzyme modification with N-bromosuccinimide in the presence of adenosine and EHNA analogues
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    
    S. Mardanyan et al., "Tryptophan environment in adenosine deaminase I. Enzyme modification with N-bromosuccinimide in the presence of adenosine and EHNA analogues", BBA-PROT ST, 1546(1), 2001, pp. 185-195
28. Gerlt, JA; Babbitt, PC
    Divergent evolution of enzymatic function: Mechanistically diverse superfamilies and functionally distinct suprafamilies
    ANNUAL REVIEW OF BIOCHEMISTRY
    
    J.A. Gerlt e P.C. Babbitt, "Divergent evolution of enzymatic function: Mechanistically diverse superfamilies and functionally distinct suprafamilies", ANN R BIOCH, 70, 2001, pp. 209-246
29. Smiley, JA; Hay, KM; Levison, BS
    A reexamination of the substrate utilization of 2-thioorotidine-5 '-monophosphate by yeast orotidine-5 '-monophosphate decarboxylase
    BIOORGANIC CHEMISTRY
    
    J.A. Smiley et al., "A reexamination of the substrate utilization of 2-thioorotidine-5 '-monophosphate by yeast orotidine-5 '-monophosphate decarboxylase", BIOORG CHEM, 29(2), 2001, pp. 96-106
30. Motherwell, WB; Bingham, MJ; Six, Y
    Recent progress in the design and synthesis of artificial enzymes
    TETRAHEDRON
    
    W.B. Motherwell et al., "Recent progress in the design and synthesis of artificial enzymes", TETRAHEDRON, 57(22), 2001, pp. 4663-4686
31. Sudom, AM; Prasad, L; Goldie, H; Delbaere, LTJ
    The phosphoryl-transfer mechanism of Escherichia coli phosphoenolpyruvate carboxykinase from the use of AlF3
    JOURNAL OF MOLECULAR BIOLOGY
    
    A.M. Sudom et al., "The phosphoryl-transfer mechanism of Escherichia coli phosphoenolpyruvate carboxykinase from the use of AlF3", J MOL BIOL, 314(1), 2001, pp. 83-92
32. Versees, W; Decanniere, K; Pelle, R; Depoorter, J; Brosens, E; Parkin, DW; Steyaert, J
    Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax
    JOURNAL OF MOLECULAR BIOLOGY
    
    W. Versees et al., "Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax", J MOL BIOL, 307(5), 2001, pp. 1363-1379
33. Sun, JL; Takahashi, N; Kakinuma, H; Nishi, Y
    Molecular evolution of catalytic antibodies in autoimmune mice
    JOURNAL OF IMMUNOLOGY
    
    J.L. Sun et al., "Molecular evolution of catalytic antibodies in autoimmune mice", J IMMUNOL, 167(10), 2001, pp. 5775-5785
34. Toth, AM; Liptak, MD; Phillips, DL; Shields, GC
    Accurate relative pK(a) calculations for carboxylic acids using complete basis set and Gaussian-n models combined with continuum solvation methods
    JOURNAL OF CHEMICAL PHYSICS
    
    A.M. Toth et al., "Accurate relative pK(a) calculations for carboxylic acids using complete basis set and Gaussian-n models combined with continuum solvation methods", J CHEM PHYS, 114(10), 2001, pp. 4595-4606
35. Zhou, TQ; Radaev, S; Rosen, BP; Gatti, DL
    Conformational changes in four regions of the Escherichia coli ArsA ATPaselink ATP hydrolysis to ion translocation
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    T.Q. Zhou et al., "Conformational changes in four regions of the Escherichia coli ArsA ATPaselink ATP hydrolysis to ion translocation", J BIOL CHEM, 276(32), 2001, pp. 30414-30422
36. Paul, S; Tramontano, A; Gololobov, G; Zhou, YX; Taguchi, H; Karle, S; Nishiyama, Y; Planque, S; George, S
    Phosphonate ester probes for proteolytic antibodies
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    S. Paul et al., "Phosphonate ester probes for proteolytic antibodies", J BIOL CHEM, 276(30), 2001, pp. 28314-28320
37. Miller, BG; Snider, MJ; Wolfenden, R; Short, SA
    Dissecting a charged network at the active site of orotidine-5 '-phosphatedecarboxylase
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    B.G. Miller et al., "Dissecting a charged network at the active site of orotidine-5 '-phosphatedecarboxylase", J BIOL CHEM, 276(18), 2001, pp. 15174-15176
38. Deerfield, DW; Carter, CW; Pedersen, LG
    Models for protein-zinc ion binding sites. II. The catalytic sites
    INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
    
    D.W. Deerfield et al., "Models for protein-zinc ion binding sites. II. The catalytic sites", INT J QUANT, 83(3-4), 2001, pp. 150-165
39. Grembecka, J; Kedzierski, P; Sokalski, WA; Leszczynski, J
    Electrostatic models of inhibitory activity
    INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
    
    J. Grembecka et al., "Electrostatic models of inhibitory activity", INT J QUANT, 83(3-4), 2001, pp. 180-192
40. Tsaramyrsi, M; Kavousanaki, D; Raptopoulou, CP; Terzis, A; Salifoglou, A
    Systematic synthesis, structural characterization, and reactivity studies of vanadium(V)-citrate anions [VO2(C6H6O7)](2)(2-), isolated from aqueous solutions in the presence of different cations
    INORGANICA CHIMICA ACTA
    
    M. Tsaramyrsi et al., "Systematic synthesis, structural characterization, and reactivity studies of vanadium(V)-citrate anions [VO2(C6H6O7)](2)(2-), isolated from aqueous solutions in the presence of different cations", INORG CHIM, 320(1-2), 2001, pp. 47-59
41. Hati, S; Batchelor, RJ; Einstein, FWB; Tracey, AS
    Vanadium(V) complexes of alpha-hydroxycarboxylic acids in aqueous solution
    INORGANIC CHEMISTRY
    
    S. Hati et al., "Vanadium(V) complexes of alpha-hydroxycarboxylic acids in aqueous solution", INORG CHEM, 40(24), 2001, pp. 6258-6265
42. Berg, OG; Gelb, MH; Tsai, MD; Jain, MK
    Interfacial enzymology: The secreted phospholipase A(2)-paradigm
    CHEMICAL REVIEWS
    
    O.G. Berg et al., "Interfacial enzymology: The secreted phospholipase A(2)-paradigm", CHEM REV, 101(9), 2001, pp. 2613-2653
43. Hoess, RH
    Protein design and phage display
    CHEMICAL REVIEWS
    
    R.H. Hoess, "Protein design and phage display", CHEM REV, 101(10), 2001, pp. 3205-3218
44. Tatulian, SA
    Toward understanding interfacial activation of secretory phospholipase A(2) (PLA(2)): Membrane surface properties and membrane-induced structural changes in the enzyme contribute synergistically to PLA(2) activation
    BIOPHYSICAL JOURNAL
    
    S.A. Tatulian, "Toward understanding interfacial activation of secretory phospholipase A(2) (PLA(2)): Membrane surface properties and membrane-induced structural changes in the enzyme contribute synergistically to PLA(2) activation", BIOPHYS J, 80(2), 2001, pp. 789-800
45. Cox, JD; Cama, E; Colleluori, DM; Pethe, S; Boucher, JL; Mansuy, D; Ash, DE; Christianson, DW
    Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase
    BIOCHEMISTRY
    
    J.D. Cox et al., "Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase", BIOCHEM, 40(9), 2001, pp. 2689-2701
46. Trehan, I; Beadle, BM; Shoichet, BK
    Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site
    BIOCHEMISTRY
    
    I. Trehan et al., "Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site", BIOCHEM, 40(27), 2001, pp. 7992-7999
47. Jackman, JE; Raetz, CRH; Fierke, CA
    Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site
    BIOCHEMISTRY
    
    J.E. Jackman et al., "Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site", BIOCHEM, 40(2), 2001, pp. 514-523
48. Kaur, K; Pratt, RF
    Mechanism of reaction of acyl phosph(on)ates with the beta-lactamase of Enterobacter cloacae P99
    BIOCHEMISTRY
    
    K. Kaur e R.F. Pratt, "Mechanism of reaction of acyl phosph(on)ates with the beta-lactamase of Enterobacter cloacae P99", BIOCHEM, 40(15), 2001, pp. 4610-4621
49. Lee, WH; Giotto, MTD; Marangoni, S; Toyama, MH; Polikarpov, I; Garratt, RC
    Structural basis for low catalytic activity in Lys49 phospholipases A2 - Ahypothesis: The crystal structure of piratoxin II complexed to fatty acid
    BIOCHEMISTRY
    
    W.H. Lee et al., "Structural basis for low catalytic activity in Lys49 phospholipases A2 - Ahypothesis: The crystal structure of piratoxin II complexed to fatty acid", BIOCHEM, 40(1), 2001, pp. 28-36
50. Bruggemann, O
    Chemical reaction engineering using molecularly imprinted polymeric catalysts
    ANALYTICA CHIMICA ACTA
    
    O. Bruggemann, "Chemical reaction engineering using molecularly imprinted polymeric catalysts", ANALYT CHIM, 435(1), 2001, pp. 197-207
51. Perrin, DM; Garestier, T; Helene, C
    Bridging the gap between proteins and nucleic acids: A metal-independent RNAseA mimic with two protein-like functionalities
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    
    D.M. Perrin et al., "Bridging the gap between proteins and nucleic acids: A metal-independent RNAseA mimic with two protein-like functionalities", J AM CHEM S, 123(8), 2001, pp. 1556-1563
52. Wittinghofer, A; Waldmann, H
    Ras - A molecular switch involved in tumor formation
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    
    A. Wittinghofer e H. Waldmann, "Ras - A molecular switch involved in tumor formation", ANGEW CHEM, 39(23), 2000, pp. 4193-4214
53. Avalle, B; Friboulet, A; Thomas, D
    Enzymes and abzymes relationships
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    
    B. Avalle et al., "Enzymes and abzymes relationships", J MOL CAT B, 10(1-3), 2000, pp. 39-45
54. Page, MGF
    beta-lactamase inhibitors
    DRUG RESISTANCE UPDATES
    
    M.G.F. Page, "beta-lactamase inhibitors", DRUG RESIST, 3(2), 2000, pp. 109-125
55. Minasov, G; Matulic-Adamic, J; Wilds, CJ; Haeberli, P; Usman, N; Beigelman, L; Egli, M
    Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines
    RNA-A PUBLICATION OF THE RNA SOCIETY
    
    G. Minasov et al., "Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines", RNA, 6(11), 2000, pp. 1516-1528
56. Paetzel, M; Danel, F; de Castro, L; Mosimann, SC; Page, MGP; Strynadka, NCJ
    Crystal structure of the class D beta-lactamase OXA-10
    NATURE STRUCTURAL BIOLOGY
    
    M. Paetzel et al., "Crystal structure of the class D beta-lactamase OXA-10", NAT ST BIOL, 7(10), 2000, pp. 918-925
57. Slocum, RD; Nichols, HF; Williamson, CL
    Purification and characterization of Arabidopsis ornithine transcarbamoylase (OTCase), a member of a distinct and evolutionarily-conserved group of plant OTCases
    PLANT PHYSIOLOGY AND BIOCHEMISTRY
    
    R.D. Slocum et al., "Purification and characterization of Arabidopsis ornithine transcarbamoylase (OTCase), a member of a distinct and evolutionarily-conserved group of plant OTCases", PL PHYS BIO, 38(4), 2000, pp. 279-288
58. Braig, K; Menz, RI; Montgomery, MG; Leslie, AGW; Walker, JE
    Structure of bovine mitochondrial F-1-ATPase inhibited by Mg(2+)ADP and aluminium fluoride
    STRUCTURE WITH FOLDING & DESIGN
    
    K. Braig et al., "Structure of bovine mitochondrial F-1-ATPase inhibited by Mg(2+)ADP and aluminium fluoride", STRUCT F D, 8(6), 2000, pp. 567-573
59. Bompard-Gilles, C; Villeret, V; Davies, GJ; Fanuel, L; Joris, B; Frere, JM; Van Beeumen, J
    A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-Ala-esterase/amidase from Ochrobactrum anthropi
    STRUCTURE WITH FOLDING & DESIGN
    
    C. Bompard-Gilles et al., "A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-Ala-esterase/amidase from Ochrobactrum anthropi", STRUCT F D, 8(2), 2000, pp. 153-162
60. Dessen, A
    Phospholipase A(2) enzymes: structural diversity in lipid messenger metabolism
    STRUCTURE WITH FOLDING & DESIGN
    
    A. Dessen, "Phospholipase A(2) enzymes: structural diversity in lipid messenger metabolism", STRUCT F D, 8(2), 2000, pp. R15-R22
61. Maveyraud, L; Golemi, D; Kotra, LP; Tranier, S; Vakulenko, S; Mobashery, S; Samama, JP
    Insights into class D beta-lactamases are revealed by the crystal structure of the OXA10 enzyme from Pseudomonas aeruginosa
    STRUCTURE
    
    L. Maveyraud et al., "Insights into class D beta-lactamases are revealed by the crystal structure of the OXA10 enzyme from Pseudomonas aeruginosa", STRUCTURE, 8(12), 2000, pp. 1289-1298
62. Hutter, MC; Helms, V
    Phosphoryl transfer by a concerted reaction mechanism in UMP/CMP-kinase
    PROTEIN SCIENCE
    
    M.C. Hutter e V. Helms, "Phosphoryl transfer by a concerted reaction mechanism in UMP/CMP-kinase", PROTEIN SCI, 9(11), 2000, pp. 2225-2231
63. Reiter, LA; Martinelli, GJ; Reeves, LA; Mitchell, PG
    Difluoroketones as inhibitors of matrix metalloprotease-13
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    L.A. Reiter et al., "Difluoroketones as inhibitors of matrix metalloprotease-13", BIOORG MED, 10(14), 2000, pp. 1581-1584
64. Golinelli-Pimpaneau, B
    Novel reactions catalysed by antibodies
    CURRENT OPINION IN STRUCTURAL BIOLOGY
    
    B. Golinelli-Pimpaneau, "Novel reactions catalysed by antibodies", CURR OP STR, 10(6), 2000, pp. 697-708
65. Maury, G
    The enantioselectivity of enzymes involved in current antiviral therapy using nucleoside analogues: a new strategy?
    ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    
    G. Maury, "The enantioselectivity of enzymes involved in current antiviral therapy using nucleoside analogues: a new strategy?", ANTIVIR CHE, 11(3), 2000, pp. 165-189
66. Whitcombe, MJ; Alexander, C; Vulfson, EN
    Imprinted polymers: Versatile new tools in synthesis
    SYNLETT
    
    M.J. Whitcombe et al., "Imprinted polymers: Versatile new tools in synthesis", SYNLETT, (6), 2000, pp. 911-923
67. Collinsova, M; Jiracek, J
    Phosphinic acid compounds in biochemistry, biology and medicine
    CURRENT MEDICINAL CHEMISTRY
    
    M. Collinsova e J. Jiracek, "Phosphinic acid compounds in biochemistry, biology and medicine", CURR MED CH, 7(6), 2000, pp. 629-647
68. Grembecka, J; Sokalski, WA; Kafarski, P
    Computer-aided design and activity prediction of leucine aminopeptidase inhibitors
    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
    
    J. Grembecka et al., "Computer-aided design and activity prediction of leucine aminopeptidase inhibitors", J COMPUT A, 14(6), 2000, pp. 531-544
69. Shiotsuki, T; Bonning, BC; Hirai, M; Kikuchi, K; Hammock, BD
    Characterization and affinity purification of juvenile hormone esterase from Bombyx mori
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    
    T. Shiotsuki et al., "Characterization and affinity purification of juvenile hormone esterase from Bombyx mori", BIOS BIOT B, 64(8), 2000, pp. 1681-1687
70. Ladner, JE; Reddy, P; Davis, A; Tordova, M; Howard, AJ; Gilliland, GL
    The 1.30 angstrom resolution structure of the Bacillus subtilis chorismatemutase catalytic homotrimer
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    
    J.E. Ladner et al., "The 1.30 angstrom resolution structure of the Bacillus subtilis chorismatemutase catalytic homotrimer", ACT CRYST D, 56, 2000, pp. 673-683
71. Lamotte-Brasseur, J; Dubus, A; Wade, RC
    pK(a) calculations for class C beta-lactamases: The role of Tyr-150
    PROTEINS-STRUCTURE FUNCTION AND GENETICS
    
    J. Lamotte-Brasseur et al., "pK(a) calculations for class C beta-lactamases: The role of Tyr-150", PROTEINS, 40(1), 2000, pp. 23-28
72. O'Connor, CJ; Manuel, RD
    Inhibiting the activity of calf pregastric lipase: Effect of bile salts, lecithin, liposomes, phenyl boronic acid and diethyl 4-nitrophenyl phosphate
    JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
    
    C.J. O'Connor e R.D. Manuel, "Inhibiting the activity of calf pregastric lipase: Effect of bile salts, lecithin, liposomes, phenyl boronic acid and diethyl 4-nitrophenyl phosphate", J BIOACT C, 15(6), 2000, pp. 489-502
73. Erxleben, A; Hermann, J
    Di- and poly-nuclear zinc(II) Schiff base complexes: synthesis, structuralstudies and reaction with an alpha-amino acid
    JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS
    
    A. Erxleben e J. Hermann, "Di- and poly-nuclear zinc(II) Schiff base complexes: synthesis, structuralstudies and reaction with an alpha-amino acid", J CHEM S DA, (4), 2000, pp. 569-575
74. Liou, JY; Huang, TM; Chang, GG
    Inhibition of octopus glutathione transferase by Meisenheimer complex analog, S-(2,4,6-trinitrophenyl) glutathione
    JOURNAL OF PROTEIN CHEMISTRY
    
    J.Y. Liou et al., "Inhibition of octopus glutathione transferase by Meisenheimer complex analog, S-(2,4,6-trinitrophenyl) glutathione", J PROTEIN C, 19(7), 2000, pp. 615-620
75. Kirby, AJ; Hollfelder, F; Tawfik, DS
    Nonspecific catalysis by protein surfaces
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
    
    A.J. Kirby et al., "Nonspecific catalysis by protein surfaces", APPL BIOC B, 83(1-3), 2000, pp. 173-180
76. DeSilva, BS; Orosz, G; Egodage, KL; Carlson, RG; Schowen, RL; Wilson, GS
    Catalytic antibodies for complex reactions - Hapten design and the importance of screening for catalysis in the generation of catalytic antibodies for the NDA/CN reaction
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
    
    B.S. DeSilva et al., "Catalytic antibodies for complex reactions - Hapten design and the importance of screening for catalysis in the generation of catalytic antibodies for the NDA/CN reaction", APPL BIOC B, 83(1-3), 2000, pp. 195-206
77. Maas, S; Rich, A
    Changing genetic information through RNA editing
    BIOESSAYS
    
    S. Maas e A. Rich, "Changing genetic information through RNA editing", BIOESSAYS, 22(9), 2000, pp. 790-802
78. Stevenson, JD; Thomas, NR
    Catalytic antibodies and other biomimetic catalysts
    NATURAL PRODUCT REPORTS
    
    J.D. Stevenson e N.R. Thomas, "Catalytic antibodies and other biomimetic catalysts", NAT PROD R, 17(6), 2000, pp. 535-577
79. Knaggs, AR
    The biosynthesis of shikimate metabolites
    NATURAL PRODUCT REPORTS
    
    A.R. Knaggs, "The biosynthesis of shikimate metabolites", NAT PROD R, 17(3), 2000, pp. 269-292
80. Caramelo, JJ; Florin-Christensen, J; Florin-Christensen, M; Delfino, JM
    Mapping the catalytic pocket of phospholipases A(2) and C using a novel set of phosphatidylcholines
    BIOCHEMICAL JOURNAL
    
    J.J. Caramelo et al., "Mapping the catalytic pocket of phospholipases A(2) and C using a novel set of phosphatidylcholines", BIOCHEM J, 346, 2000, pp. 679-690
81. Mohr, D; Wintermeyer, W; Rodnina, MV
    Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome
    EMBO JOURNAL
    
    D. Mohr et al., "Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome", EMBO J, 19(13), 2000, pp. 3458-3464
82. Porter, DJT
    Escherichia coli cytosine deaminase: the kinetics and thermodynamics for binding of cytosine to the apoenzyme and the Zn2+ holoenzyme are similar
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    
    D.J.T. Porter, "Escherichia coli cytosine deaminase: the kinetics and thermodynamics for binding of cytosine to the apoenzyme and the Zn2+ holoenzyme are similar", BBA-PROT ST, 1476(2), 2000, pp. 239-252
83. Matoba, Y; Kumagai, T; Sugiyama, M
    Crystallization and preliminary X-ray diffraction studies of Streptomyces phospholipase A(2) in a calcium-binding form
    JOURNAL OF INORGANIC BIOCHEMISTRY
    
    Y. Matoba et al., "Crystallization and preliminary X-ray diffraction studies of Streptomyces phospholipase A(2) in a calcium-binding form", J INORG BIO, 82(1-4), 2000, pp. 221-223
84. Mouratou, B; Gramatikova, S; Kunz, B; Christen, P
    Amino acid sequences and hapten binding of catalytic and noncatalytic antibodies against N-alpha-(5 '-phosphopyridoxyl)-L-lysine
    MOLECULAR IMMUNOLOGY
    
    B. Mouratou et al., "Amino acid sequences and hapten binding of catalytic and noncatalytic antibodies against N-alpha-(5 '-phosphopyridoxyl)-L-lysine", MOL IMMUNOL, 37(11), 2000, pp. 633-640
85. Allison, WS; Ren, HM; Dou, C
    Inhibitory Mg-ADP-fluoroaluminate complexes bound to catalytic sites of F-1-ATPases: Are they ground-state or transition-state analogs?
    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
    
    W.S. Allison et al., "Inhibitory Mg-ADP-fluoroaluminate complexes bound to catalytic sites of F-1-ATPases: Are they ground-state or transition-state analogs?", J BIOENER B, 32(5), 2000, pp. 531-538
86. Janin, J; Dumas, C; Morera, S; Xu, YW; Meyer, P; Chiadmi, M; Cherfils, J
    Three-dimensional structure of nucleoside diphosphate kinase
    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
    
    J. Janin et al., "Three-dimensional structure of nucleoside diphosphate kinase", J BIOENER B, 32(3), 2000, pp. 215-225
87. Hilvert, D
    Critical analysis of antibody catalysis
    ANNUAL REVIEW OF BIOCHEMISTRY
    
    D. Hilvert, "Critical analysis of antibody catalysis", ANN R BIOCH, 69, 2000, pp. 751-793
88. Souza, DHF; Selistre-de-Araujo, HS; Garratt, RC
    Determination of the three-dimensional structure of toxins by protein crystallography
    TOXICON
    
    D.H.F. Souza et al., "Determination of the three-dimensional structure of toxins by protein crystallography", TOXICON, 38(10), 2000, pp. 1307-1353
89. El Ashry, ESH; Rashed, N; Shobier, AHS
    Glycosidase inhibitors and their chemotherapeutic value, part 1
    PHARMAZIE
    
    E.S.H. El Ashry et al., "Glycosidase inhibitors and their chemotherapeutic value, part 1", PHARMAZIE, 55(4), 2000, pp. 251-262
90. Atanasov, BP; Mustafi, D; Makinen, MW
    Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    B.P. Atanasov et al., "Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases", P NAS US, 97(7), 2000, pp. 3160-3165
91. Kolesnikov, AV; Kozyr, AV; Alexandrova, ES; Koralewski, F; Demin, AV; Titov, MI; Avalle, B; Tramontano, A; Paul, S; Thomas, D; Gabibov, AG; Friboulet, A
    Enzyme mimicry by the antiidiotypic antibody approach
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    A.V. Kolesnikov et al., "Enzyme mimicry by the antiidiotypic antibody approach", P NAS US, 97(25), 2000, pp. 13526-13531
92. Sellergren, B; Karmalkar, RN; Shea, KJ
    Enantioselective ester hydrolysis catalyzed by imprinted polymers. 2
    JOURNAL OF ORGANIC CHEMISTRY
    
    B. Sellergren et al., "Enantioselective ester hydrolysis catalyzed by imprinted polymers. 2", J ORG CHEM, 65(13), 2000, pp. 4009-4027
93. McCall, KA; Huang, CC; Fierke, CA
    Function and mechanism of zinc metalloenzymes
    JOURNAL OF NUTRITION
    
    K.A. McCall et al., "Function and mechanism of zinc metalloenzymes", J NUTR, 130(5), 2000, pp. 1437S-1446S
94. Sakakibara, K; Shimazaki, K; Chen, KH; Lii, JH
    Molecular mechanics (MM3) calculations on phosphonamidate compounds
    JOURNAL OF MOLECULAR STRUCTURE
    
    K. Sakakibara et al., "Molecular mechanics (MM3) calculations on phosphonamidate compounds", J MOL STRUC, 556(1-3), 2000, pp. 283-291
95. Takahashi, N; Kakinuma, H; Hamada, K; Shimazaki, K; Yamasaki, Y; Matsushita, H; Nishi, Y
    Improved generation of catalytic antibodies by MRL/MPJ-lpr/lpr autoimmune mice
    JOURNAL OF IMMUNOLOGICAL METHODS
    
    N. Takahashi et al., "Improved generation of catalytic antibodies by MRL/MPJ-lpr/lpr autoimmune mice", J IMMUNOL M, 235(1-2), 2000, pp. 113-120
96. Kast, P; Grisostomi, C; Chen, IA; Li, SL; Krengel, U; Xue, YF; Hilvert, D
    A strategically positioned cation is crucial for efficient catalysis by chorismate mutase
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    P. Kast et al., "A strategically positioned cation is crucial for efficient catalysis by chorismate mutase", J BIOL CHEM, 275(47), 2000, pp. 36832-36838
97. Clabecq, A; Henry, JP; Darchen, F
    Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    A. Clabecq et al., "Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP", J BIOL CHEM, 275(41), 2000, pp. 31786-31791
98. Savelsbergh, A; Mohr, D; Wilden, B; Wintermeyer, W; Rodnina, MV
    Stimulation of the GTPase activity of translation elongation factor G by ribosomal protein L7/12
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    A. Savelsbergh et al., "Stimulation of the GTPase activity of translation elongation factor G by ribosomal protein L7/12", J BIOL CHEM, 275(2), 2000, pp. 890-894
99. Keefe, RG; Maley, GF; Saxl, RL; Maley, F
    A T4-phage deoxycytidylate deaminase mutant that no longer requires deoxycytidine 5 '-triphosphate for activation
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    R.G. Keefe et al., "A T4-phage deoxycytidylate deaminase mutant that no longer requires deoxycytidine 5 '-triphosphate for activation", J BIOL CHEM, 275(17), 2000, pp. 12598-12602
100. Bearne, SL; Blouin, C
     Inhibition of Escherichia coli glucosamine-6 phosphate synthase by reactive intermediate analogues - The role of the 2-amino function in catalysis
     JOURNAL OF BIOLOGICAL CHEMISTRY
     
     S.L. Bearne e C. Blouin, "Inhibition of Escherichia coli glucosamine-6 phosphate synthase by reactive intermediate analogues - The role of the 2-amino function in catalysis", J BIOL CHEM, 275(1), 2000, pp. 135-140