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Linkage disequilibrium and haplotype analysis among eight novel single-nucleotide polymorphisms in the human tissue-type plasminogen activator (t-PA)gene
JOURNAL OF HUMAN GENETICS
Effects of low-molecular-weight heparin treatment on fibrinolytic markers in unstable coronary artery disease
FIBRINOLYSIS & PROTEOLYSIS
Alteplase activity
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
Plasma levels of total plasminogen activator inhibitor-I (PAI-I) and tPA/PAI-1 complex in patients with disseminated intravascular coagulation and thrombotic thrombocytopenic purpura
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
Hemostatic and fibrinolytic status in patients with ovarian cancer and benign ovarian cysts: Could D-dimer and antithrombin III levels be included asprognostic markers for survival outcome?
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
Protective effects of pamiteplase, a modified t-PA, in a rat model of embolic stroke
NEUROREPORT
Maximal endothelial tissue plasminogen activator release is not impaired in patients with acute coronary syndromes before heparin treatment
BLOOD COAGULATION & FIBRINOLYSIS
Thrombin converts singlet oxygen (O-1(2))-oxidized fibrinogen into a soluble t-PA cofactor - A new method for preparing a stimulator for functional t-PA assays
ANNALS OF HEMATOLOGY
Plasminogen activator inhibitor type-1 (part two): Role for failure of thrombolytic therapy. PAI-1 resistance as a potential benefit for new fibrinolytic agents
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Influence of sugar chain on fibrin affinity of recombinant t-PA
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Update on intravenous tissue plasminogen activator for acute stroke: from clinical trials to clinical practice
CANADIAN MEDICAL ASSOCIATION JOURNAL
Pharmacokinetic studies of Gln117 tissue-type plasminogen activator in rats
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Expression of mRNA for plasminogen activators and protease nexin-1 in innervated and denervated mouse skeletal muscle
JOURNAL OF NEUROSCIENCE RESEARCH
Early inhibition of activated fibrinolysis predicts microbial infection, shock and mortality in febrile medical patients
THROMBOSIS AND HAEMOSTASIS
Fibrinolysis/proteolysis balance in stable angina pectoris in relation to angiographic findings
THROMBOSIS AND HAEMOSTASIS
Methodology for the Canadian Activase For Stroke Effectiveness Study (CASES)
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
Autoantibodies to receptor induced neoepitopes of fibrinolytic proteins inrheumatic and vascular diseases
JOURNAL OF RHEUMATOLOGY
Elevation of plasma free PAI-1 levels as an integrated endothelial response to severe burns
BURNS
Some indices of haemostasis during Lewis lung carcinoma growth
EXPERIMENTAL ONCOLOGY
ATTEMPTS: A heparin/protamine-based prodrug approach for delivery of thrombolytic drugs
JOURNAL OF CONTROLLED RELEASE
Issues in the assessment of the safety and efficacy of tenecteplase (TNK-tPA)
CLINICAL CARDIOLOGY
Ethanol-induced increased surface-localized fibrinolytic activity in cultured human endothelial cells: Kinetic analysis
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
Effects of acute methionine loading and vitamin C on endogenous fibrinolysis, endothelium-dependent vasomotion and platelet aggregation
CLINICAL SCIENCE
Bolus fibrinolytic therapy in acute myocardial infarction
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation
CRITICAL CARE MEDICINE
Induction of hepatic tissue-type plasminogen activator and type 1 plasminogen activator-inhibitor gene expressions and appearance of their translation products in the bile following acute liver injury in rats
THROMBOSIS RESEARCH
Method to measure in vivo blood fibrinolytic activity with a I-125-fibrin coated aorta loop validated with agents which affect blood fibrinolytic activity
THROMBOSIS RESEARCH
Interaction of fibrinolysis and prothrombotic risk factors in neonates, infants and children with and without thromboembolism and underlying cardiac disease - A prospective study
THROMBOSIS RESEARCH
Pharmacokinetic properties of a novel tissue-type plasminogen activator pamiteplase after single intravenous administration to rats, dogs, and monkeys
THROMBOSIS RESEARCH
Treatment with tissue plasminogen activator and inpatient mortality rates for patients with ischemic stroke treated in community hospitals
STROKE
Intravenous tPA for ischemic stroke team performance over time, safety, and efficacy in a single-center, 2-year experience
STROKE
Effects of hyperbaric oxygen on expression of fibrinolytic factors of human endothelium in a simulated ischaemia/reperfusion situation
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
Regulation of plasmin-dependent fibrin clot lysis by annexin II heterotetramer
JOURNAL OF BIOLOGICAL CHEMISTRY
S100A13 participates in the release of fibroblast growth factor 1 in response to heat shock in vitro
JOURNAL OF BIOLOGICAL CHEMISTRY
Ectopic expression of the cAMP-responsive element binding protein inhibitsphorbol ester-mediated induction of tissue-type plasminogen activator geneexpression
EUROPEAN JOURNAL OF BIOCHEMISTRY
Fibrinolysis for acute myocardial infarction - Current status and new horizons for pharmacological reperfusion, Part 1
CIRCULATION
Thrombolysis failure: A role for plasminogen activator inhibitor type 1 (PAI-1)
BRITISH JOURNAL OF HAEMATOLOGY
Production of tissue plasminogen activator (t-PA) in Aspergillus niger
BIOTECHNOLOGY AND BIOENGINEERING
Glucose-based optimization of CHO-cell perfusion cultures
BIOTECHNOLOGY AND BIOENGINEERING
Improving natural principles with genetic engineering: TNK-tissue plasminogen activator
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
Pregnancy zone protein-tissue-type plasminogen activator complexes bind tolow-density lipoprotein receptor-related protein (LRP)
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Angiotensin, fibrinolysis, and vascular homeostasis
AMERICAN JOURNAL OF CARDIOLOGY
A randomized trial confirming the efficacy of reduced dose recombinant tissue plasminogen activator in a Chinese myocardial infarction population anddemonstrating superiority to usual dose urokinase: The TUCC trial
AMERICAN HEART JOURNAL
Deconstructing the interaction of glu-plasminogen with its receptor alpha-enolase
FIBRINOLYSIS & PROTEOLYSIS
Fibrinolytic parameters in young adults: the Floren-teen (Florence Teenager) Study
FIBRINOLYSIS & PROTEOLYSIS
Decreased synthesis of tissue plasminogen activator antigen in users of oral contraceptives
FIBRINOLYSIS & PROTEOLYSIS
Preserved tissue-type plasminogen activator release and endothelium-dependent vasodilation in postmenopausal women with NIDDM
JOURNAL OF DIABETES AND ITS COMPLICATIONS
Thrombolytic therapy with use of alteplase (rt-PA) in peripheral arterial occlusive disease: Review of the clinical literature
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
Fibrinolysis: an unfinished agenda
BLOOD COAGULATION & FIBRINOLYSIS
A residential study comparing the effects of diets rich in stearic acid, oleic acid, and linoleic acid on fasting blood lipids, hemostatic variables and platelets in young healthy men
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Exercise and endothelial function
CORONARY ARTERY DISEASE
Exercise and thrombosis
CORONARY ARTERY DISEASE
Influence of N-terminal peptide and oligosaccharide on the clearance of t-PA
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Fibrinolytic factors and atherothrombotic events: epidemiological evidence
ANNALS OF MEDICINE
Lack of t-PA use for acute ischemic stroke in a community hospital: High incidence of exclusion criteria
AMERICAN JOURNAL OF EMERGENCY MEDICINE
Renin-angiotensin-aldosterone system and fibrinolysis
MEDIZINISCHE KLINIK
Mechanism of enhancement by fucoidan and CNBr-fibrinogen digest of the activation of glu-plasminogen by tissue plasminogen activator
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
Fibrinogen Bellingham: A gamma-chain R275C substitution and a beta-promoter polymorphism in a thrombotic member of an asymptomatic family
AMERICAN JOURNAL OF HEMATOLOGY
Decreased tissue factor and tissue-plasminogen activator antigen in relapsed acute promyelocytic leukemia
AMERICAN JOURNAL OF HEMATOLOGY
Immunoassays for the quantitation of porcine PAI-1 antigen and activity inbiological fluid samples
THROMBOSIS AND HAEMOSTASIS
Fluid shear stress increases the intra-cellular storage pool of tissue-type plasminogen activator in intact human conduit vessels
THROMBOSIS AND HAEMOSTASIS
Enhanced tissue factor pathway activity and fibrin turnover in the alveolar compartment of patients with interstitial lung disease
THROMBOSIS AND HAEMOSTASIS
Cellular degradation of free and inhibitor-bound tissue-type plasminogen activator - Requirement for a co-receptor?
THROMBOSIS AND HAEMOSTASIS
Formation, inhibition and clearance of plasmin in vivo
HAEMOSTASIS
Serine protease inhibitors: Novel therapeutic targets for stroke?
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Ethanol-induced up-regulation of candidate plasminogen receptor annexin IIin cultured human endothelial cells
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
A study of the interaction between Helicobacter pylori and components of the human fibrinolytic system
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
The hepatic clearance of recombinant tissue-type plasminogen activator decreases after an inflammatory stimulus
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
Use of tissue-type plasminogen activator for acute ischemic stroke - The Cleveland area experience
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Antithrombotic regulation in human endothelial cells by fibrinolytic factors
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Effects of beta 2-glycoprotein I and monoclonal anticardiolipin antibodieson extrinsic fibrinolysis
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Determination, pharmacokinetics and protein binding of a novel tissue-typeplasminogen activator, pamiteplase in human plasma
XENOBIOTICA
The role of the t-PA I/D and PAI-1 4G/5G polymorphisms in African-Americanadults with a diagnosis of myocardial infarction or venous thromboembolism
THROMBOSIS RESEARCH
Effect of temperature and incubation time on D-dimer serum levels in healthy subjects
THROMBOSIS RESEARCH
Increase of efficacy of thrombolytic therapy in acute myocardial infarction by improvement of the characteristics of new fibrinolytic agents
WIENER KLINISCHE WOCHENSCHRIFT
The cytosolic hyaluronic acid level defines some clinical-biological properties of CD44v5-positive infiltrating ductal carcinomas of the breast
MEDICINA CLINICA
Binding of mutant tissue-type plasminogen activators to human endothelial cells and their extracellular matrix
LIFE SCIENCES
Biochemical properties of the fibrinogen component of a fibrin glue beforeand after severe dry heat treatment
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
Spatial regulation and activity modulation of plasmin by high affinity binding to the G domain of the alpha(3) subunit of laminin-5
JOURNAL OF BIOLOGICAL CHEMISTRY
Induction of endometrial plasminogen activator-inhibitor 1: a possible mechanism contributing to the effect of intrauterine levonorgestrel in the treatment of menorrhagia
FERTILITY AND STERILITY
Overexpression of a dominant negative CREB protein in HT-1080 cells selectively disrupts plasminogen activator inhibitor type 2 but not tissue-type plasminogen activator gene expression
FEBS LETTERS
Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects
DIABETES
Measurement of different forms of tissue plasminogen activator in plasma
CLINICAL CHEMISTRY
Fibrinolytic actions of intra-arterial angiotensin II and bradykinin in vivo in man
CARDIOVASCULAR RESEARCH
Antibodies to tissue-type plasminogen activator in plasma from patients with primary antiphospholipid syndrome
BRITISH JOURNAL OF HAEMATOLOGY
Vascular release of plasminogen activator inhibitor-1 impairs fibrinolysisduring acute arterial thrombosis in mice
BLOOD
Limitations to the amplification and stability of human tissue-type plasminogen activator expression by Chinese hamster ovary cells
BIOTECHNOLOGY AND BIOENGINEERING
Conversion of fibrinogen to fibrin: Mechanism of exposure of tPA- and plasminogen-binding sites
BIOCHEMISTRY
Regulation of plasmin activity by annexin II tetramer
BIOCHEMISTRY
Third-generation thrombolytic drugs
AMERICAN JOURNAL OF MEDICINE
Alterations in the fibrinolytic system components during acute myocardial infarction
ACTA CARDIOLOGICA
Fibrinolysis and thrombosis
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
Fibrinolysis in open abdominal aortic aneurysm surgery
FIBRINOLYSIS & PROTEOLYSIS
Endothelin-1 does not contribute to the release of tissue plasminogen activator in vivo in man
FIBRINOLYSIS & PROTEOLYSIS
Thrombolysis in acute myocardial infarction: analysis of studies comparingaccelerated t-PA and streptokinase
JOURNAL OF ACCIDENT & EMERGENCY MEDICINE
Candidates for thrombolytic treatment in acute ischaemic stroke - where are our patients in Hong Kong?
JOURNAL OF ACCIDENT & EMERGENCY MEDICINE
Treatment with hyperbaric oxygen affects endothelial cell fibrinolysis
EUROPEAN JOURNAL OF SURGERY
Storage of tissue-type plasminogen activator in Weibel-Palade bodies of human endothelial cells
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Idiopathic central serous chorioretinopathy: Promoting factors
ANNALS OF OPHTHALMOLOGY & GLAUCOMA
Role of annexin II tetramer in plasminogen activation
TRENDS IN CARDIOVASCULAR MEDICINE