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IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production
NATURE IMMUNOLOGY
Menstrual cycle-specific inhibition of endometrial stromal cell proliferation by oncostatin M
MOLECULAR HUMAN REPRODUCTION
Leptin: brains and bones
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Reactive oxygen species regulate heat-shock protein 70 via the JAK/STAT pathway
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3
CYTOKINE
Interleukin-6 family cytokines: signaling and effects in human airway smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Increased binding of IFN regulating factor 1 mediates the synergistic induction of CIITA by IFN-gamma and tumor necrosis factor-alpha in human thyroid carcinoma cells
INTERNATIONAL IMMUNOLOGY
Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation
ONCOGENE
Transposon mutagenesis of Campylobacter jejuni identifies a bipartite energy taxis system required for motility
MOLECULAR MICROBIOLOGY
Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines
DEVELOPMENT
Possible participation of a JAK2 signaling pathway in recombinant rat interleukin-5-induced prolongation of rat eosinophil survival
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Control of nitrogen and carbon metabolism in cyanobacteria
JOURNAL OF APPLIED PHYCOLOGY
Inhibitory effects of anti-inflammatory drugs on interleukin-6 bioactivity
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Molecular cloning of horse Hsp90 cDNA and its comparative analysis with other vertebrate Hsp90 sequences
JOURNAL OF VETERINARY MEDICAL SCIENCE
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
FASEB JOURNAL
Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein
FREE RADICAL BIOLOGY AND MEDICINE
Tumor necrosis factor alpha-induced osteoclastogenesis requires tumor necrosis factor receptor-associated factor 6
JOURNAL OF BONE AND MINERAL RESEARCH
Genomic organization of the gene for mouse PIAS gamma and analysis of its promoter
GENE
Expression of mRNAs for ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and their receptors (CNTFR alpha,LIFR beta, IL-6R alpha, and gp130) in human peripheral neuropathies
NEUROCHEMICAL RESEARCH
Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
The central pyrogenic action of interleukin-6 is related to nuclear translocation of STAT3 in the anteroventral preoptic area of the rat brain
JOURNAL OF THERMAL BIOLOGY
How circulating cytokines trigger the neural circuits that control the hypothalamic-pituitary-adrenal axis
PSYCHONEUROENDOCRINOLOGY
Sp1 is required for prolactin activation of the interferon regulatory factor-1 gene
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Differential phosphorylation of Janus kinase 2, Stat5A and Stat5B in response to growth hormone in primary rat adipocytes
MOLECULAR AND CELLULAR ENDOCRINOLOGY
DNA damage signalling and NF-kappa B: implications for survival and death in mammalian cells
BIOCHEMICAL SOCIETY TRANSACTIONS
Advanced glycation end product-induced proliferation in NRK-49F cells is dependent on the JAK2/STAT5 pathway and cyclin D1
AMERICAN JOURNAL OF KIDNEY DISEASES
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene activation in the liver
MOLECULAR AND CELLULAR BIOLOGY
LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1
BIOCHEMICAL JOURNAL
Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins
BIOCHEMICAL JOURNAL
The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokine
EMBO JOURNAL
Interleukin-6 inhibits radiation induced apoptosis in pancreatic cancer cells
ANTICANCER RESEARCH
Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
The soluble IL-6 receptors: Serum levels and biological function
CELLULAR AND MOLECULAR BIOLOGY
Mediators of inflammation and acute phase response in the liver
CELLULAR AND MOLECULAR BIOLOGY
IL-11: Insights in asthma from overexpression transgenic modeling
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Role of T-bet in commitment of T(H)1 cells before IL-12-dependent selection
SCIENCE
Identification of the domain in the human interleukin-11 receptor that mediates ligand binding
JOURNAL OF MOLECULAR BIOLOGY
Myocardial ischemia activates the JAK-STAT pathway through angiotensin II signaling in in vivo myocardium of rats
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Interleukin-6-resistant melanoma cells exhibit reduced activation of STAT3and lack of inhibition of cyclin E-associated kinase activity
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Activation of eotaxin-3/CCL26 gene expression in human dermal fibroblasts is mediated by STAT6
JOURNAL OF IMMUNOLOGY
Unexpected characteristics of the IFN-gamma reporters in nontransformed T cells
JOURNAL OF IMMUNOLOGY
A mandatory role for STAT4 in IL-12 induction of mouse T cell CCR5
JOURNAL OF IMMUNOLOGY
STAT6 mediates eotaxin-1 expression in IL-4 or TNF-alpha-induced fibroblasts
JOURNAL OF IMMUNOLOGY
Soluble interleukin-6 receptor activates the human papillomavirus type 18 long control region in SW756 cervical carcinoma cells in a STAT3-dependent manner
JOURNAL OF GENERAL VIROLOGY
Novel cell type-specific antiviral mechanism of interferon gamma action inmacrophages
JOURNAL OF EXPERIMENTAL MEDICINE
Interleukin 12 p40 production by barrier epithelial cells during airway inflammation
JOURNAL OF EXPERIMENTAL MEDICINE
Molecular cloning and characterisation of a novel membrane receptor gene from the lobster Jasus edwardsii
JOURNAL OF EXPERIMENTAL BIOLOGY
Interaction of interleukin-6 on human granulosa cell steroid secretion
JOURNAL OF ENDOCRINOLOGY
Neurohormonal regulation of myocardial cell apoptosis during the development of heart failure
JOURNAL OF CELLULAR PHYSIOLOGY
The Stat1 binding motif of the interferon-gamma receptor is sufficient to mediate Stat5 activation and its repression by SOCS3
JOURNAL OF BIOLOGICAL CHEMISTRY
Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3 beta - Impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression
JOURNAL OF BIOLOGICAL CHEMISTRY
Mapping of a region within the N terminus of Jak1 involved in cytokine receptor interaction
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of distinct roles for a dileucine and a tyrosine internalization motif in the interleukin (IL)-13 binding component IL-13 receptor alpha 2 chain
JOURNAL OF BIOLOGICAL CHEMISTRY
gp130 plays a critical role in pressure overload-induced cardiac hypertrophy
JOURNAL OF BIOLOGICAL CHEMISTRY
Conversion of threonine 757 to valine enhances stat5a transactivation potential
JOURNAL OF BIOLOGICAL CHEMISTRY
Interleukin-6-induced tethering of STAT3 to the LAP/C/EBP beta promoter suggests a new mechanism of transcriptional regulation by STAT3
JOURNAL OF BIOLOGICAL CHEMISTRY
Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase - Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress
JOURNAL OF BIOLOGICAL CHEMISTRY
The IL-6 receptor antagonist SANT-7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells
INTERNATIONAL JOURNAL OF CANCER
All-trans-retinoic acid and polyriboinosinic: polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity
IMMUNOLOGY
Activation of the JAK/STAT pathway by ceramide in cultured human fibroblasts
FEBS LETTERS
A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130
FEBS LETTERS
Insulin modulates leptin-induced STAT3 activation in rat hypothalamus
FEBS LETTERS
Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation
FEBS LETTERS
Cross-talk between IL-6 and TGF-beta signaling in hepatoma cells
FEBS LETTERS
Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells
FEBS LETTERS
Soluble interleukin-6 receptor a inhibits the cytokine-induced fractalkine/CX3CL1 expression in human vascular endothelial cells in culture
EXPERIMENTAL CELL RESEARCH
Differential requirement of CD28 for IL-12 receptor expression and function in CD4(+) and CD8(+) T cells
EUROPEAN JOURNAL OF IMMUNOLOGY
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
EUROPEAN JOURNAL OF BIOCHEMISTRY
Temporal relationship between the sexually dimorphic spontaneous GH secretory profiles and hepatic STAT5 activity
ENDOCRINOLOGY
Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism
CLINICAL BIOCHEMISTRY
Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571
BLOOD
STAT3 is constitutively activated in Hodgkin cell lines
BLOOD
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus
BLOOD
Replacing factor-dependency with that for lysozyme: Affordable culture of IL-6-dependent hybridoma by transfecting artificial cell surface receptor
BIOTECHNOLOGY AND BIOENGINEERING
In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130
BIOCHEMISTRY
Association of MUC-1 and PSGL-1 with low-density microdomain in T-lymphocytes: A preliminary note
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Inactivation of NF-kappa B involved in osteoblast development through interleukin-6
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
The direct effect of IL-12 on tumor cells: IL-12 acts directly on tumor cells to activate NF-kappa B and enhance IFN-gamma-mediated STAT1 phosphorylation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
X-linked vacuolated myopathy - TNF-alpha and IFN-gamma expression in muscle fibers with MHC class I on sarcolemma
AMERICAN JOURNAL OF PATHOLOGY
Dendritic cell regulation of T(H)1-T(H)2 development
NATURE IMMUNOLOGY
Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse STAT2
NATURE IMMUNOLOGY
Oncostatin M is produced during pregnancy by decidual cells and stimulatesthe release of HCG
MOLECULAR HUMAN REPRODUCTION
Increased T-lymphocyte interleukin-6 binding in patients with multiple sclerosis
EUROPEAN JOURNAL OF NEUROLOGY
Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1
CELL DEATH AND DIFFERENTIATION
Relationship between circulating interleukin-10 (IL-10) with interleukin-6(IL-6) type cytokines (IL-6, interleukin-11 (IL-11), oncostatin M (OSM)) and soluble interleukin-6 receptor (sIL-6R) in patients with multiple myeloma
EUROPEAN CYTOKINE NETWORK
G-CSF receptor expression in ovarian cancer
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Quiescence of CD34-negative haematopoietic stem cells is mediated by downregulation of cyclin B and no STAT activation
CYTOKINE
Analysis of soluble interleukin 6 receptor in cerebrospinal fluid in inflammatory and non-inflammatory conditions
CYTOKINE
Constitutive expression of IL-6-like cytokines in normal bone marrow: Implications for pathophysiology of myeloma
CYTOKINE
Proliferation of immature myeloma cells by interleukin-6 is associated with CD45 expression in human multiple myeloma
LEUKEMIA & LYMPHOMA
Structural and functional studies on the leukemia inhibitory factor receptor (LIF-R): Gene and soluble form of LIF-R, and cytoplasmic domain of LIF-Rrequired for differentiation and growth arrest of myeloid leukemic cells
LEUKEMIA & LYMPHOMA
Leptin receptor and leukemia
LEUKEMIA & LYMPHOMA
AP-1 and STAT mediate hyperoxia-induced gene transcription of heme oxygenase-1
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Interleukin-6-induced tyrosine phosphorylation of phospholipase C-gamma 1 in PC12 cells
MOLECULES AND CELLS
Association of STATs with relatives and friends
TRENDS IN CELL BIOLOGY
Interleukin-6 inhibits neurotransmitter release and the spread of excitation in the rat cerebral cortex
EUROPEAN JOURNAL OF NEUROSCIENCE
Preface: STAT signaling
ONCOGENE
Complex roles of Stat1 in regulating gene expression
ONCOGENE