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    1. Hawkey, CJ
      COX-1 and COX-2 inhibitors

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    2. Smiles, J; Walker, R
      Selective cyclo-oxygenase-2 inhibitor-induced oliguria: a postoperative complication

      INTERNAL MEDICINE JOURNAL
    3. Werner, U; Werner, D; Mundkowski, R; Gillich, M; Brune, K
      Selective and rapid liquid chromatography-mass spectrometry method for thequantification of rofecoxib in pharmacokinetic studies with humans

      JOURNAL OF CHROMATOGRAPHY B

    4. 2-(acetoxyphenyl)-(Z)-styryl sulfides as cyclooxygenase inhibitors

      EXPERT OPINION ON THERAPEUTIC PATENTS

    5. Upper gastrointestinal complications: The causes, consequences, and clinical outcomes

      AMERICAN JOURNAL OF MANAGED CARE
    6. Mazenko, RS; Skarbek, A; Woolf, EJ; Simpson, RC; Matuszewski, BK
      Sample preparation via solid phase extraction in the 96-well format for HPLC/UV detection-based biofluid assays. Application to the determination of a novel cyclooxygenase II inhibitor in human plasma and urine

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    7. Francois, D
      Spin doctors

      JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
    8. McKenna, F; Weaver, A; Fiechtner, JJ; Bello, AE; Fort, JG
      COX-2 specific inhibitors in the management of osteoarthritis of the knee:A placebo-controlled, randomized, double-blind study

      JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
    9. Chauret, N; Yergey, JA; Brideau, C; Friesen, RW; Mancini, J; Riendeau, D; Silva, J; Styhler, A; Trimble, LA; Nicoll-Griffith, DA
      In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663)

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    10. Lanas, A
      Nonsteroidal anti-inflammatory drugs, low-dose aspirin, and potential waysof reducing the risk of complications

      EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
    11. Huang, JJ; Taguchi, A; Hsu, HP; Andriole, GL; Kurz, A
      Preoperative oral rofecoxib does not decrease postoperative pain or morphine consumption in patients after radical prostatectomy: A prospective, randomized, double-blinded, placebo-controlled trial

      JOURNAL OF CLINICAL ANESTHESIA
    12. Simon, LS
      Cox-2 inhibitors - Are they nonsteroidal anti-inflammatory drugs with a better safety profile?

      GASTROENTEROLOGY CLINICS OF NORTH AMERICA
    13. Bell, GM; Schnitzer, TJ
      Cox-2 inhibitors and other nonsteroidal anti-inflammatory drugs in the treatment of pain in the elderly

      CLINICS IN GERIATRIC MEDICINE
    14. Radhakrishna, T; Rao, DS; Reddy, GO
      LC determination of rofecoxib in bulk and pharmaceutical formulations

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    15. Bannwarth, B
      COX-2 specific inhibitors: Are NSAIDs and the stomach become reconciled?

      GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
    16. Hochberg, MC
      What have we learned from the large outcomes trials of COX-2 selective inhibitors? The rheumatologist's perspective

      CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
    17. Appel, GB
      COX-2 inhibitors and the kidney

      CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
    18. Patrono, C
      Measurement of cyclooxygenase isozyme inhibition in humans: exploring the clinical relevance of biochemical selectivity

      CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
    19. Brune, K; Neubert, A
      Pharmacokinetic and pharmacodynamic aspects of the ideal COX-2 inhibitor: a pharmacologist's perspective

      CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
    20. Day, RO
      Pharmacokinetic and pharmacodynamic aspects of the ideal COX-2 inhibitor: a rheumatologist's perspective

      CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
    21. Kerr, RG; Al-Kawan, RH
      Osteoarthritis - A primary care approach for physicians in 2000 and beyond

      SAUDI MEDICAL JOURNAL
    22. Sorbera, LA; Castaner, RM; Silvestre, J; Castaner, J
      Etoricoxib - Analgesic drug, antiarthritic, cyclooxygenase-2 inhibitor

      DRUGS OF THE FUTURE
    23. Detora, LM; Krupa, D; Bolognese, J; Sperling, RS; Ehrich, EW
      Rofecoxib shows consistent efficacy in osteoarthritis clinical trials, regardless of specific patient demographic and disease factors

      JOURNAL OF RHEUMATOLOGY
    24. Acevedo, E; Castaneda, O; Ugaz, M; Beaulieu, AD; Pons-Estel, B; Caeiro, F; Casas, N; Garza-Elizondo, M; Irazoque, F; Hinojosa, W; Gutierrez-Urena, S; Vandormael, K; Rodgers, DB; Laurenzi, M
      Tolerability profiles of rofecoxib (Vioxx (R)) and Arthrotoc (R) - A comparison of six weeks treatment in patients with osteoarthritis

      SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
    25. Steinfeld, S; Poriau, S
      Patient and physician satisfaction with rofecoxib in osteoarthritis: Results of the EVA (experience with VIOXX in arthritis) survey

      CURRENT MEDICAL RESEARCH AND OPINION
    26. Dicker, AP; Williams, TL; Grant, DS
      Targeting angiogenic processes by combination rofecoxib and ionizing radiation

      AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
    27. Pall, M; Friden, BE; Brannstrom, M
      Induction of delayed follicular rupture in the human by the selective COX-2 inhibitor rofecoxib: a randomized double-blind study

      HUMAN REPRODUCTION
    28. Brater, DC; Harris, C; Redfern, JS; Gertz, BJ
      Renal effects of COX-2-selective inhibitors

      AMERICAN JOURNAL OF NEPHROLOGY
    29. Hachulla, E
      Specific inhibitors of Cox-2 and hemostasis the internists point of view

      REVUE DE MEDECINE INTERNE
    30. Salter, EA; Wierzbicki, A; Sperl, G; Thompson, WJ
      Molecular modeling study of COX-2 inhibition by diarylheterocycles and sulindac sulfide

      JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
    31. Laudanno, OM; Cesolari, JA; Esnarriaga, J; Rista, L; Piombo, G; Maglione, C; Aramberry, L; Sambrano, J; Godoy, A; Rocaspana, A
      Gastrointestinal damage induced by celecoxib and rofecoxib in rats

      DIGESTIVE DISEASES AND SCIENCES
    32. Weaver, AL
      Rofecoxib: Clinical pharmacology and clinical experience

      CLINICAL THERAPEUTICS
    33. Chang, DJ; Fricke, JR; Bird, SR; Bohidar, NR; Dobbins, TW; Geba, GP
      Rofecoxib versus codeine/acetaminophen in postoperative dental pain: A double-blind, randomized, placebo- and active comparator-controlled clinical trial

      CLINICAL THERAPEUTICS
    34. Zhao, SZ; Reynolds, MW; Lefkowith, J; Whelton, A; Arellano, FM
      A comparison of renal-related adverse drug reactions between rofecoxib andcelecoxib, based on the World Health Organization Uppsala Monitoring Centre safety database

      CLINICAL THERAPEUTICS
    35. Pellissier, JM; Straus, WL; Watson, DJ; Kong, SX; Harper, SE
      Economic evaluation of rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs for the treatment of osteoarthritis

      CLINICAL THERAPEUTICS
    36. Schnitzer, TJ
      Osteoarthritis management: The role of cyclooxygenase-2-selective inhibitors

      CLINICAL THERAPEUTICS
    37. Asero, R
      Tolerability of rofecoxib

      ALLERGY
    38. Hinrichs, R; Ritzkowsky, A; Hunzelmann, N; Krieg, T; Scharffetter-Kochanek, K
      Rofecoxib as an alternative in aspirin hypersensitivity

      ALLERGY
    39. Berges-Gimeno, MP; Camacho-Garrido, E; Garcia-Rodriguez, RM; Alfaya, T; Garcia, CM; Hinojosa, M
      Rofecoxib safe in NSAID hypersensitivity

      ALLERGY
    40. Mukherjee, D; Nissen, SE; Topol, EJ
      Risk of cardiovascular events associated with selective COX-2 inhibitors

      JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
    41. Konstam, MA; Demopoulos, LA
      Cardiovascular events and COX-2 inhibitors

      JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
    42. Bjarnason, I; Rainsford, KD
      Are cyclooxygenase 2 inhibitors free of gastrointestinal side effects?

      WESTERN JOURNAL OF MEDICINE
    43. Fosslien, E
      Review: Molecular pathology of cyclooxygenase-2 in cancer-induced angiogenesis

      ANNALS OF CLINICAL AND LABORATORY SCIENCE
    44. Stevenson, DD; Simon, RA
      Lack of cross-reactivity between rofecoxib and aspirin in aspirin-sensitive patients with asthma

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    45. Yergey, JA; Trimble, LA; Silva, J; Chauret, N; Li, C; Therien, M; Grimm, E; Nicoll-Griffith, DA
      In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization

      DRUG METABOLISM AND DISPOSITION
    46. Kammerl, MC; Nusing, RM; Seyberth, HW; Riegger, GAJ; Kurtz, A; Kramer, BK
      Inhibition of cyclooxygenase-2 attenuates urinary prostanoid excretion without affecting renal renin expression

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    47. Ouellet, M; Riendeau, D; Percival, MD
      A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    48. Riendeau, D; Percival, MD; Brideau, C; Charleson, S; Dube, D; Ethier, D; Falgueyret, JP; Friesen, RW; Gordon, R; Greig, G; Guay, J; Mancini, J; Ouellet, M; Wong, E; Xu, L; Boyce, S; Visco, D; Girard, Y; Prasit, P; Zamboni, R; Rodger, IW; Gresser, M; Ford-Hutchinson, AW; Young, RN; Chan, CC
      Etoricoxib (MK-0663): Preclinical profile and comparison with other agentsthat selectively inhibit cyclooxygenase-2

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    49. Patrono, C; Patrignani, P; Rodriguez, LAG
      Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs

      JOURNAL OF CLINICAL INVESTIGATION
    50. Stichtenoth, DO; Frolich, JC
      Therapy with preferential and specific COX-2 inhibitors

      INTERNIST
    51. Matheson, AJ; Figgitt, DP
      Rofecoxib - A review of its use in the management of osteoarthritis, acutepain and rheumatoid arthritis

      DRUGS
    52. Kanmerl, MC; Nusing, RM; Schweda, F; Endemann, D; Stubanus, M; Kees, F; Lackner, KJ; Fischereder, M; Kramer, BK
      Low sodium and furosemide-induced stimulation of the renin system in man is mediated by cyclooxygenase 2

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    53. Konstam, MA; Weir, MR; Reicin, A; Shapiro, D; Sperling, RS; Barr, E; Gertz, BJ
      Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib

      CIRCULATION
    54. Gupta, S; Crofford, LJ
      An update on specific COX-2 inhibitors: The COXIBs

      BULLETIN ON THE RHEUMATIC DISEASES
    55. Gretzer, B; Maricic, N; Respondek, M; Schuligoi, R; Peskar, BM
      Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge

      BRITISH JOURNAL OF PHARMACOLOGY
    56. Scott-Lennox, JA; McLaughlin-Miley, C; Lennox, RD; Bohling, AM; Cutler, BL; Yan, CQ; Jaffe, M
      Stratification of flare intensity identifies placebo responders in a treatment efficacy trial of patients with osteoarthritis

      ARTHRITIS AND RHEUMATISM
    57. Brandt, KD
      A critique of the 2000 update of the American College of Rheumatology recommendations for management of hip and knee osteoarthritis

      ARTHRITIS AND RHEUMATISM
    58. Brideau, C; Van Staden, C; Chan, CC
      In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats

      AMERICAN JOURNAL OF VETERINARY RESEARCH
    59. Pasero, C; McCaffery, M
      Selective COX-2 inhibitors

      AMERICAN JOURNAL OF NURSING
    60. Conti, F; Spinelli, FR; Ossandon, A; Valesini, G
      Selective cyclooxygenase-2 inhibition: Biological and clinical effects

      ISRAEL MEDICAL ASSOCIATION JOURNAL
    61. Sunshine, A
      A comparison of the newer COX-2 drugs and older nonnarcotic oral analgesics

      JOURNAL OF PAIN
    62. Payne, R
      Limitations of NSAIDs for pain management: Toxicity or lack of efficacy?

      JOURNAL OF PAIN
    63. Steinmeyer, J
      Pharmacological basis for the therapy of pain and inflammation with nonsteroidal anti-inflammatory drugs

      ARTHRITIS RESEARCH
    64. Chavez-Eng, CM; Constanzer, ML; Matuszewski, BK
      Determination of Rofecoxib (MK-0966), a cyclooxygenase-2 inhibitor, in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

      JOURNAL OF CHROMATOGRAPHY B
    65. Dajani, EZ; Klamut, MJ
      Novel therapeutic approaches to gastric and duodenal ulcers: an update

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    66. Carter, JS
      Inhibitors of cyclooxygenase-2: November 1999-April 2000

      EXPERT OPINION ON THERAPEUTIC PATENTS
    67. Schuna, AA; Megeff, C
      New drugs for the treatment of rheumatoid arthritis

      AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
    68. Everts, B; Wahrborg, P; Hedner, T
      COX-2-specific inhibitors - the emergence of a new class of analgesic and anti-inflammatory drugs

      CLINICAL RHEUMATOLOGY
    69. Ehrich, EW; Davies, GM; Watson, DJ; Bolognese, JA; Seidenberg, BC; Bellamy, N
      Minimal perceptible clinical improvement with the Western Ontario and McMaster universities osteoarthritis index questionnaire and global assessmentsin patients with osteoarthritis

      JOURNAL OF RHEUMATOLOGY
    70. Knott, L
      Treating osteoarthritis in practice - The TOP study

      CURRENT MEDICAL RESEARCH AND OPINION
    71. Chiolero, A; Wurzner, G; Burnier, M
      Specific inhibitors of type 2 cyclooxygenase less renal effects than classical non steroidal anti-inflammatory agents?

      NEPHROLOGIE
    72. Enrique, E; Cistero-Bahima, A; San Miguel-Moncin, MM; Alonso, R
      Rofecoxib should be tried in NSAID hypersensitivity

      ALLERGY
    73. Lichtenstein, DR; Wolfe, MM
      COX-2-Selective NSAIDs - New and improved?

      JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
    74. Depre, M; Ehrich, E; Van Hecken, A; De Lepeleire, I; Dallob, A; Wong, P; Porras, A; Gertz, BJ; De Schepper, PJ
      Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    75. Brooks, PM; Day, RO
      COX-2 inhibitors

      MEDICAL JOURNAL OF AUSTRALIA
    76. Sigthorsson, G; Crane, R; Simon, T; Hoover, M; Quan, H; Bolognese, J; Bjarnason, I
      COX-2 inhibition with rofecoxib does not increase intestinal permeability in healthy subjects: a double blind crossover study comparing rofecoxib with placebo and indomethacin

      GUT
    77. Hinz, B; Brune, K
      Specific COX-2 inhibitors. Basis and options of a pharmacotherapeutical concept

      ANAESTHESIST
    78. Noble, SL; King, DS; Olutade, JI
      Cyclooxygenase-2 enzyme inhibitors: Place in therapy

      AMERICAN FAMILY PHYSICIAN
    79. Woolf, E; Fu, I; Matuszewski, B
      Determination of rofecoxib, a cyclooxygenase-2 specific inhibitor, in human plasma using high-performance liquid chromatography with post-column photochemical derivatization and fluorescence detection

      JOURNAL OF CHROMATOGRAPHY B
    80. Cano, DL; Rodriguez, BG; Dominguez, YT; Delgado, PH; Esteban, JMH; Gutierrez, JMH
      The brand new selective COX-2 inhibitors NSAIDs.

      REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
    81. Kaplan-Machlis, B; Klostermeyer, BS
      The cyclooxygenase-2 inhibitors: Safety and effectiveness

      ANNALS OF PHARMACOTHERAPY
    82. Ehrich, EW; Schnitzer, TJ; McIlwain, H; Levy, R; Wolfe, F; Weisman, M; Zeng, Q; Morrison, B; Bolognese, J; Seidenberg, B; Gertz, BJ
      Effect of specific COX-2 inhibition in osteoarthritis of the knee: A 6 week double blind, placebo controlled pilot study of rofecoxib

      JOURNAL OF RHEUMATOLOGY
    83. Fung, HB; Kirschenbaum, HL
      Selective cyclooxygenase-2 inhibitors for the treatment of arthritis

      CLINICAL THERAPEUTICS
    84. Malmstrom, K; Daniels, S; Kotey, P; Seidenberg, BC; Desjardins, PJ
      Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, inpostoperative dental pain: A randomized, placebo- and active-comparator-controlled clinical trial

      CLINICAL THERAPEUTICS
    85. Schnitzer, TJ; Truitt, K; Fleischmann, R; Dalgin, P; Block, J; Zeng, Q; Bolognese, J; Seidenberg, B; Ehrich, EW
      The safety profile, tolerability, and effective dose range of rofecoxib inthe treatment of rheumatoid arthritis

      CLINICAL THERAPEUTICS
    86. Mitchell, JA; Warner, TD
      Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance toNSAID therapy

      BRITISH JOURNAL OF PHARMACOLOGY


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Documento generato il 02/06/20 alle ore 20:44:45