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    1. Sastre, M; Steiner, H; Fuchs, K; Capell, A; Multhaup, G; Condron, MM; Teplow, DB; Haass, C
      Presenilin dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

      EMBO REPORTS
    2. Chen, FS; Yu, G; Arawaka, S; Nishimura, M; Kawarai, T; Yu, H; Tandon, A; Supala, A; Song, YQ; Rogaeva, E; Milman, P; Sato, C; Yu, C; Janus, C; Lee, J; Song, LX; Zhang, LL; Fraser, PE; St George-Hyslop, PH
      Nicastrin binds to membrane tethered Notch

      NATURE CELL BIOLOGY
    3. Petit, A; Bihel, F; da Costa, CA; Pourquie, O; Checler, F; Kraus, JL
      New protease inhibitors prevent gamma-secretase-mediated production of A beta 40/42 without affecting Notch cleavage

      NATURE CELL BIOLOGY
    4. Davidsson, P; Bogdanovic, N; Lannfelt, L; Blennow, K
      Reduced expression of amyloid precursor protein, presenilin-1 and rab3a incortical brain regions in Alzheimer's disease

      DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
    5. Huse, JT; Doms, RW
      Neurotoxic traffic: Uncovering the mechanics of amyloid production in Alzheimer's disease

      TRAFFIC
    6. Jankowsky, JL; Slunt, HH; Ratovitski, T; Jenkins, NA; Copeland, NG; Borchelt, DR
      Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

      BIOMOLECULAR ENGINEERING
    7. Jhee, S; Shiovitz, T; Crawford, AW; Cutler, NR
      beta-amyloid therapies in Alzheimer's disease

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    8. Dominguez, DI; De Strooper, B; Annaert, W
      Secretases as therapeutic targets for the treatment of Alzheimer's disease

      AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
    9. Calabrese, EJ
      Amyloid beta-peptide: Biphasic dose responses

      CRITICAL REVIEWS IN TOXICOLOGY
    10. Refolo, LM; Pappolla, MA; LaFrancois, J; Malester, B; Schmidt, SD; Thomas-Bryant, T; Tint, GS; Wang, R; Mercken, M; Petanceska, SS; Duff, KE
      A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenicmouse model of Alzheimer's disease

      NEUROBIOLOGY OF DISEASE
    11. Poduslo, JF; Curran, GL; Wengenack, TM; Malester, B; Duff, K
      Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease

      NEUROBIOLOGY OF DISEASE
    12. Leissring, MA; LaFerla, FM; Callamaras, N; Parker, I
      Subcellular mechanisms of presenilin-mediated enhancement of calcium signaling

      NEUROBIOLOGY OF DISEASE
    13. Eckert, A; Schindowski, K; Leutner, S; Luckhaus, C; Touchet, N; Czech, C; Muller, WE
      Alzheimer's disease-like alterations in peripheral cells from presenilin-1transgenic mice

      NEUROBIOLOGY OF DISEASE
    14. Russo, C; Salis, S; Dolcini, V; Venezia, V; Song, XH; Teller, JK; Schettini, G
      Identification of amino-terminally and phosphotyrosine-modified carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain

      NEUROBIOLOGY OF DISEASE
    15. De Jonghe, C; Esselens, C; Kumar-Singh, S; Craessaerts, K; Serneels, S; Checler, F; Annaert, W; Van Broeckhoven, C; De Strooper, B
      Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect A beta secretion and APP C-terminal fragment stability

      HUMAN MOLECULAR GENETICS
    16. Roberds, SL; Anderson, J; Basi, G; Bienkowski, MJ; Branstetter, DG; Chen, KS; Freedman, SB; Frigon, NL; Games, D; Hu, K; Johnson-Wood, K; Kappenman, KE; Kawabe, TT; Kola, I; Kuehn, R; Lee, M; Liu, WQ; Motter, R; Nichols, NF; Power, M; Robertson, DW; Schenk, D; Schoor, M; Shopp, GM; Shuck, ME; Sinha, S; Svensson, KA; Tatsuno, G; Tintrup, H; Wijsman, J; Wright, S; McConlogue, L
      BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

      HUMAN MOLECULAR GENETICS
    17. Presente, A; Andres, A; Nye, JS
      Requirement of Notch in adulthood for neurological function and longevity

      NEUROREPORT
    18. Lukiw, WJ; Gordon, WC; Rogaev, EI; Thompson, H; Bazan, NG
      Presenilin-2 (PS2) expression up-regulation in a model of retinopathy of prematurity and pathoangiogenesis

      NEUROREPORT
    19. Walter, J; Kaether, C; Steiner, H; Haass, C
      The cell biology of Alzheimer's disease: uncovering the secrets of secretases

      CURRENT OPINION IN NEUROBIOLOGY
    20. Fortini, ME
      Notch and Presenilin: a proteolytic mechanism emerges

      CURRENT OPINION IN CELL BIOLOGY
    21. Matsumoto, A; Itoh, K; Seki, T; Motozaki, K; Matsuyama, S
      Human brain carboxypeptidase B, which cleaves beta-amyloid peptides in vitro, is expressed in the endoplasmic reticulum of neurons

      EUROPEAN JOURNAL OF NEUROSCIENCE
    22. Demeester, N; Mertens, C; Caster, H; Goethals, M; Vandekerckhove, J; Rosseneu, M; Labeur, C
      Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides

      EUROPEAN JOURNAL OF NEUROSCIENCE
    23. Koizumi, K; Nakajima, M; Yuasa, S; Saga, Y; Sakai, T; Kuriyama, T; Shirasawa, T; Koseki, H
      The role of presenilin 1 during somite segmentation

      DEVELOPMENT
    24. Paganelli, AR; Ocana, OH; Prat, MI; Franco, PG; Lopez, SL; Morelli, L; Adamo, AM; Riccomagno, MM; Matsubara, E; Shoji, M; Affranchino, JL; Castano, EM; Carrasco, AE
      The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis

      MECHANISMS OF DEVELOPMENT
    25. Imaizumi, K; Miyoshi, K; Katayama, T; Yoneda, T; Taniguchi, M; Kudo, T; Tohyama, M
      The unfolded protein response and Alzheimer's disease

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    26. Bertram, L; Tanzi, RE
      Dancing in the dark? The status of late-onset Alzheimer's disease genetics

      JOURNAL OF MOLECULAR NEUROSCIENCE
    27. Hartmann, D; Tournoy, J; Saftig, P; Annaert, W; De Strooper, B
      Implication of APP secretases in notch signaling

      JOURNAL OF MOLECULAR NEUROSCIENCE
    28. Thinakaran, G
      Metabolism of presenilins

      JOURNAL OF MOLECULAR NEUROSCIENCE
    29. Steiner, H; Haass, C
      Nuclear signaling - A common function of presenilin substrates?

      JOURNAL OF MOLECULAR NEUROSCIENCE
    30. Mattson, MP; Chan, SL
      Dysregulation of cellular calcium homeostasis in Alzheimer's disease - Badgenes and bad habits

      JOURNAL OF MOLECULAR NEUROSCIENCE
    31. Schenk, D; Games, D; Seubert, P
      Potential treatment opportunities for Alzheimer's disease through inhibition of secretases and A beta immunization

      JOURNAL OF MOLECULAR NEUROSCIENCE
    32. Pinnix, I; Council, JE; Roseberry, B; Onstead, L; Mallender, W; Sucic, J; Sambamurti, K
      Convertases other than furin cleave beta-secretase to its mature form

      FASEB JOURNAL
    33. Russo, E
      Hot papers - Interpreting the signaling of notch - Comment

      SCIENTIST
    34. Ertekin-Taner, N; Graff-Radford, N; Younkin, LH; Eckman, C; Adamson, J; Schaid, DJ; Blangero, J; Hutton, M; Younkin, SG
      Heritability of plasma amyloid beta in typical late-onset Alzheimer's disease pedigrees

      GENETIC EPIDEMIOLOGY
    35. Vidal, R; Calero, M; Revesz, T; Plant, G; Ghiso, J; Frangione, B
      Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family

      GENE
    36. Smith, MJ; Kwok, JBJ; McLean, CA; Kril, JJ; Broe, GA; Nicholson, GA; Cappai, R; Hallupp, M; Cotton, RGH; Masters, CL; Schofield, PR; Brooks, WS
      Variable phenotype of Alzheimer's disease with spastic paraparesis

      ANNALS OF NEUROLOGY
    37. Vestling, M; Wiehager, B; Tanii, H; Cowburn, RF
      Akt activity in presenilin 1 wild-type and mutation transfected human SH-SY5Y neuroblastoma cells after serum deprivation and high glucose stress

      JOURNAL OF NEUROSCIENCE RESEARCH
    38. Popescu, BO; Cedazo-Minguez, A; Popescu, LM; Winblad, B; Cowburn, RF; Ankarcrona, M
      Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

      JOURNAL OF NEUROSCIENCE RESEARCH
    39. Dermaut, B; Roks, G; Theuns, J; Rademakers, R; Houwing-Duistermaat, JJ; Serneels, S; Hofman, A; Breteler, MMB; Cruts, M; Van Broeckhoven, C; van Duijn, CM
      Variable expression of presenilin 1 is not a major determinant of risk forlate-onset Alzheimer's Disease

      JOURNAL OF NEUROLOGY
    40. D'Andrea, MR; Nagele, RG; Wang, HY; Peterson, PA; Lee, DHS
      Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

      HISTOPATHOLOGY
    41. Layfield, R
      Does an inhibition of the uhiquitin/26S proteasome pathway of protein degradation underlie the pathogenesis of non-familial Alzheimer's disease?

      MEDICAL HYPOTHESES
    42. Matsuoka, Y; Picciano, M; La Francois, J; Duff, K
      Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse modelof Alzheimer's disease

      NEUROSCIENCE
    43. Kostyszyn, B; Cowburn, RF; Seiger, A; Kjaeldgaard, A; Sundstrom, E
      Expression of presenilin-1 and notch-1 receptor in human embryonic CNS

      NEUROSCIENCE
    44. Dowjat, WK; Wisniewski, H; Wisniewski, T
      Alzheimer's disease presenilin-1 expression modulates the assembly of neurofilaments

      NEUROSCIENCE
    45. Luetjens, CM; Lankiewicz, S; Bui, NT; Krohn, AJ; Poppe, M; Prehn, JHM
      Up-regulation of Bcl-xL in response to subtoxic beta-amyloid: Role in neuronal resistance against apoptotic and oxidative injury

      NEUROSCIENCE
    46. Mann, DMA; Takeuchi, A; Sato, S; Cairns, NJ; Lantos, PL; Rossor, MN; Haltia, M; Kalimo, H; Iwatsubo, T
      Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques

      NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
    47. Queralt, R; Ezquerra, M; Castellvi, M; Lleo, A; Blesa, R; Oliva, R
      Detection of the presenilin 1 gene mutation (M139T) in early-onset familial Alzheimer disease in Spain

      NEUROSCIENCE LETTERS
    48. Wiltfang, J; Esselmann, H; Maler, JM; Bleich, S; Huther, G; Kornhuber, J
      Molecular biology of Alzheimer's dementia and its clinical relevance to early diagnosis and new therapeutic strategies

      GERONTOLOGY
    49. Zhou, SF; Hayward, SD
      Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

      MOLECULAR AND CELLULAR BIOLOGY
    50. Pigino, G; Pelsman, A; Mori, H; Busciglio, J
      Presenilin-1 mutations reduce cytoskeletal association, deregulate neuritegrowth, and potentiate neuronal dystrophy and tau phosphorylation

      JOURNAL OF NEUROSCIENCE
    51. Fitzjohn, SM; Morton, RA; Kuenzi, F; Rosahl, TW; Shearman, M; Lewis, H; Smith, D; Reynolds, DS; Davies, CH; Collingridge, GL; Seabrook, GR
      Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant formof amyloid precursor protein

      JOURNAL OF NEUROSCIENCE
    52. Mattson, MP; Chan, SL; Camandola, S
      Presenilin mutations and calcium signaling defects in the nervous and immune systems

      BIOESSAYS
    53. Frisen, J; Lendahl, U
      Oh no, Notch again!

      BIOESSAYS
    54. Lucas, JL; Hernandez, F; Gomez-Ramos, P; Moran, MA; Hen, R; Avila, J
      Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3 beta conditional transgenic mice

      EMBO JOURNAL
    55. Ishii, K; Lippa, C; Tomiyama, T; Miyatake, F; Ozawa, K; Tamaoka, A; Hasegawa, T; Fraser, PE; Shoji, S; Nee, LE; Pollen, DA; St George-Hyslop, PH; Ii, K; Ohtake, T; Kalaria, RN; Rossor, MN; Lantos, PL; Cairns, NJ; Farrer, LA; Mori, H
      Distinguishable effects of Presenilin-1 and APP717 mutations on amyloid plaque deposition

      NEUROBIOLOGY OF AGING
    56. Gordon, MN; King, DL; Diamond, DM; Jantzen, PT; Boyett, KV; Hope, CE; Hatcher, JM; DiCarlo, G; Gottschall, WPE; Morgan, D; Arendash, GW
      Correlation between cognitive deficits and A beta deposits in transgenic APP+PS1 mice

      NEUROBIOLOGY OF AGING
    57. Dirami, G; Ravindranath, N; Achi, MV; Dym, M
      Expression of Notch pathway components in spermatogonia and Sertoli cells of neonatal mice

      JOURNAL OF ANDROLOGY
    58. Jack, C; Berezovska, O; Wolfe, MS; Hyman, BT
      Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons

      MOLECULAR BRAIN RESEARCH
    59. Chapman, PF; Falinska, AM; Knevett, SG; Ramsay, MF
      Genes, models and Alzheimer's disease

      TRENDS IN GENETICS
    60. Janson, CG; McPhee, SWJ; Leone, P; Freese, A; During, MJ
      Viral-based gene transfer to the mammalian CNS for functional genomic studies

      TRENDS IN NEUROSCIENCES
    61. Sisodia, SS; Annaert, W; Kim, SH; De Strooper, B
      gamma-secretase: Never more enigmatic

      TRENDS IN NEUROSCIENCES
    62. Fishman, CE; Cummins, DJ; Bales, KR; DeLong, CA; Esterman, MA; Hanson, JC; White, SL; Paul, SM; Jordan, WH
      Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease

      JOURNAL OF NEUROSCIENCE METHODS
    63. Law, A; Gauthier, S; Quirion, R
      Say NO to Alzheimer's disease: the putative links between nitric oxide anddementia of the Alzheimer's type

      BRAIN RESEARCH REVIEWS
    64. Sorbi, S; Forleo, P; Tedde, A; Cellini, E; Ciantelli, M; Bagnoli, S; Nacmias, B
      Genetic risk factors in familial Alzheimer's disease

      MECHANISMS OF AGEING AND DEVELOPMENT
    65. Esler, WP; Wolfe, MS
      Biomedicine - A portrait of Alzheimer secretases - New features and familiar faces

      SCIENCE
    66. Lewis, J; Dickson, DW; Lin, WL; Chisholm, L; Corral, A; Jones, G; Yen, SH; Sahara, N; Skipper, L; Yager, D; Eckman, C; Hardy, J; Hutton, M; McGowan, E
      Enhanced neurofibrillary degeneration in transgenic mice expressing mutanttau and APP

      SCIENCE
    67. Cao, XW; Sudhof, TC
      A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60

      SCIENCE
    68. Iwata, N; Tsubuki, S; Takaki, Y; Shirotani, K; Lu, B; Gerard, NP; Gerard, C; Hama, E; Lee, HJ; Saido, TC
      Metabolic regulation of brain A beta by neprilysin

      SCIENCE
    69. Hannequin, D; Campion, D
      Dominant forms of Alzheimer's disease: from genotype to phenotype.

      REVUE NEUROLOGIQUE
    70. Janus, C; Westaway, D
      Transgenic mouse models of Alzheimer's disease

      PHYSIOLOGY & BEHAVIOR
    71. Rogaeva, EA; Fafel, KC; Song, YQ; Medeiros, H; Sato, C; Liang, Y; Richard, E; Rogaev, EI; Frommelt, P; Sadovnick, AD; Meschino, W; Rockwood, K; Boss, MA; Mayeux, R; St George-Hyslop, P
      Screening for PS1 mutations in a referral-based series of AD cases - 21 Novel mutations

      NEUROLOGY
    72. De Strooper, B; Konig, G
      Alzheimer's disease - An inflammatory drug prospect

      NATURE
    73. Weggen, S; Eriksen, JL; Das, P; Sagi, SA; Wang, R; Pietrzik, CU; Findlay, KA; Smith, TW; Murphy, MP; Butler, T; Kang, DE; Marquez-Sterling, N; Golde, TE; Koo, EH
      A subset of NSAIDs lower amyloidogenic A beta 42 independently of cyclooxygenase activity

      NATURE
    74. Kitazume, S; Tachida, Y; Oka, R; Shirotani, K; Saido, TC; Hashimoto, Y
      Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    75. Levitan, D; Lee, J; Song, LX; Manning, R; Wong, G; Parker, E; Zhang, LL
      PS1N-and C-terminal fragments form a complex that functions in APP processing and Notch signaling

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    76. Hartmann, D
      From Alzheimer's disease to skin tumors: The catenin connection

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    77. Monsonego, A; Maron, R; Zota, V; Selkoe, DJ; Weiner, HL
      Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: Implications for the pathogenesis and treatment of Alzheimer's disease

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    78. Hadland, BK; Manley, NR; Su, DM; Longmore, GD; Moore, CL; Wolfe, MS; Schroeter, EH; Kopan, R
      gamma-secretase inhibitors repress thymocyte development

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    79. Fassbender, K; Simons, M; Bergmann, C; Stroick, M; Lutjohann, D; Keller, P; Runz, H; Kuhl, S; Bertsch, T; von Bergmannn, K; Hennerici, M; Beyreuther, K; Hartmann, T
      Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides A beta 42 and A beta 40 in vitro and in vivo

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    80. Kametani, F; Tanaka, K; Usami, M; Maruyama, K; Mori, H
      Human wild presenilin-1 mimics the effect of the mutant presenilin-1 on the processing of Alzheimer's amyloid precursor protein in PC12D cells

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    81. Baskin, F; Rosenberg, RN; Iyer, L; Schellenberg, GD; Hynan, L; Nee, LE
      Platelet APP isoform ratios in asymptomatic young adults expressing an AD-related presenilin-1 mutation

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    82. Tomidokoro, Y; Harigaya, Y; Matsubara, E; Ikeda, M; Kawarabayashi, T; Shirao, T; Ishiguro, K; Okamoto, K; Younkin, SG; Shoji, M
      Brain A beta amyloidosis in APPsw mice induces accumulation of presenilin-I and tau

      JOURNAL OF PATHOLOGY
    83. Le, R; Cruz, L; Urbanc, B; Knowles, RB; Hsiao-Ashe, K; Duff, K; Irizarry, MC; Stanley, HE; Hyman, BT
      Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: Implications for neural system disruption

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    84. Verkkoniemi, A; Kalimo, H; Paetau, A; Somer, M; Iwatsubo, T; Hardy, J; Haltia, M
      Variant Alzheimer disease with spastic paraparesis: Neuropathological phenotype

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    85. Takao, M; Ghetti, B; Murrell, JR; Unverzagt, FW; Giaccone, G; Tagliavini, F; Bugiani, O; Piccardo, P; Hulette, CM; Crain, BJ; Farlow, MR; Heyman, A
      Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    86. Le, TV; Crook, R; Hardy, J; Dickson, DW
      Cotton wool plaques in non-familial late-onset Alzheimer disease

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    87. Smith, IF; Boyle, JP; Vaughan, PFT; Pearson, HA; Peers, C
      Effects of chronic hypoxia on Ca2+ stores and capacitative Ca2+ entry in human neuroblastoma (SH-SY5Y) cells

      JOURNAL OF NEUROCHEMISTRY
    88. Dumanchin-Njock, C; da Costa, CA; Mercken, L; Pradier, L; Checler, F
      The caspase-derived C-terminal fragment of beta APP induces caspase-independent toxicity and triggers selective increase of A beta 42 in mammalian cells

      JOURNAL OF NEUROCHEMISTRY
    89. Cupers, P; Orlans, I; Craessaerts, K; Annaert, W; De Strooper, B
      The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

      JOURNAL OF NEUROCHEMISTRY
    90. Nakajima, M; Miura, M; Aosaki, T; Shirasawa, T
      Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro

      JOURNAL OF NEUROCHEMISTRY
    91. Wolfe, MS
      Presenilin and gamma-secretase: structure meets function

      JOURNAL OF NEUROCHEMISTRY
    92. Counts, SE; Lah, JJ; Levey, AI
      The regulation of presenilin-1 by nerve growth factor

      JOURNAL OF NEUROCHEMISTRY
    93. Skovronsky, DM; Fath, S; Lee, VMY; Milla, ME
      Neuronal localization of the TNF alpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques

      JOURNAL OF NEUROBIOLOGY
    94. Lambert, JC; Mann, DMA; Harris, JM; Chartier-Harlin, MC; Cumming, A; Coates, J; Lemmon, H; StClair, D; Iwatsubo, T; Lendon, C
      The-48 C/T polymorphism in the presenilin 1 promoter is associated with anincreased risk of developing Alzheimer's disease and an increased A beta load in brain

      JOURNAL OF MEDICAL GENETICS
    95. Vezina, J; Grossmuller, F; Muller, K
      Influence of a transiently transfected gene on apoptosis, measurements guided by cotransfected GFP

      JOURNAL OF IMMUNOLOGICAL METHODS
    96. Tomita, M; Sugi, K; Ozawa, K; Tsong, TY; Yoshimura, T
      Targeting antigen-specific receptors on B lymphocytes to generate high yields of specific monoclonal antibodies directed against biologically active lower antigenic peptides within presenilin 1

      JOURNAL OF IMMUNOLOGICAL METHODS
    97. Dingwall, C
      Spotlight on BACE: The secretases as targets for treatment in Alzheimer disease

      JOURNAL OF CLINICAL INVESTIGATION
    98. Cupers, P; Bentahir, M; Craessaerts, K; Orlans, I; Vanderstichele, H; Saftig, P; De Strooper, B; Annaert, W
      The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein

      JOURNAL OF CELL BIOLOGY
    99. Kim, JW; Chang, TS; Lee, JE; Huh, SH; Yeon, SW; Yang, WS; Joe, CO; Mook-Jung, I; Tanzi, RE; Kim, TW; Choi, EJ
      Negative regulation of the SAPK/JNK signaling pathway by presenilin 1

      JOURNAL OF CELL BIOLOGY
    100. Soriano, S; Kang, DE; Fu, MF; Pestell, R; Chevallier, N; Zheng, H; Koo, EH
      Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein andNotch processing

      JOURNAL OF CELL BIOLOGY


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Documento generato il 19/01/21 alle ore 01:10:39