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La ricerca find articoli where soggetti phrase all words 'placental' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 3178 riferimenti
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    1. Thompson, DA; McHenry, CL; Li, Y; Richards, JE; Othman, MI; Schwinger, E; Vollrath, D; Jacobson, SG; Gal, A
      Retinal dystrophy due to paternal isodisomy for chromosome 1 or chromosome2, with homoallelism for mutations in RPE65 or MERTK, respectively

      AMERICAN JOURNAL OF HUMAN GENETICS
    2. Maritz, GS; Cock, CA; Louey, S; Joyce, BJ; Albuquerque, CA; Harding, R
      Effects of fetal growth restriction on lung development before and after birth: A morphometric analysis

      PEDIATRIC PULMONOLOGY
    3. Galan, HL; Regnault, TRH; Le Cras, TD; Tyson, RW; Anthony, RV; Wilkening, RB; Abman, SH
      Cotyledon and binucleate cell nitric oxide synthase expression in an ovinemodel of fetal growth restriction

      JOURNAL OF APPLIED PHYSIOLOGY
    4. Assad, RS; Lee, FY; Hanley, FL
      Placental compliance during fetal extracorporeal circulation

      JOURNAL OF APPLIED PHYSIOLOGY
    5. Naftolin, F; Horvath, TL; Balthazart, J
      Estrogen synthetase (aromatase) immunohistochemistry reveals concordance between avian and rodent limbic systems and hypothalami

      EXPERIMENTAL BIOLOGY AND MEDICINE
    6. Matousek, J
      Ribonucleases and their antitumor activity

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
    7. Brown, CJ
      Equality of the sexes: Mammalian dosage compensation

      SEMINARS IN REPRODUCTIVE MEDICINE
    8. Robinson, WP; Beever, C; Brown, CJ; Stephenson, MD
      Skewed X inactivation and recurrent spontaneous abortion

      SEMINARS IN REPRODUCTIVE MEDICINE
    9. Limaye, LS; Kale, VP
      Cryopreservation of human hematopoietic cells with membrane stabilizers and bioantioxidants as additives in the conventional freezing medium

      JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
    10. Rice, AM; Wood, JA; Milross, CG; Collins, CJ; Case, J; Nordon, RE; Vowels, MR
      Prior cryopreservation of ex vivo-expanded cord blood cells is not detrimental to engraftment as measured in the NOD-SCID mouse model

      JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
    11. Read, JS; Tuomala, R; Kpamegan, E; Zorrilla, C; Landesman, S; Brown, G; Vajaranant, M; Hammill, H; Thompson, B
      Mode of delivery and postpartum morbidity among HIV-infected women: The Women and Infants Transmission Study

      JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
    12. Reed, W; Walters, M; Trachtenberg, E; Smith, R; Lubin, BH
      Sibling donor cord blood banking for children with sickle cell disease

      PEDIATRIC PATHOLOGY & MOLECULAR MEDICINE
    13. Mitchell, NJ
      The energetics of endotrophic development in the frog Geocrinia vitellina (Anura : Myobatrachinae)

      PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY
    14. Thompson, MB; Speake, BK; Russell, KJ; McCartney, RJ
      Nutrient uptake by embryos of the Australian viviparous lizard Eulamprus tympanum

      PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY
    15. Wallace, J; Bourke, D; Da Silva, P; Aitken, R
      Nutrient partitioning during adolescent pregnancy

      REPRODUCTION
    16. McMillen, IC; Adams, MB; Ross, JT; Coulter, CL; Simonetta, G; Owens, JA; Robinson, JS; Edwards, LJ
      Fetal growth restriction: adaptations and consequences

      REPRODUCTION
    17. Symonds, ME; Budge, H; Stephenson, T; McMillen, IC
      Fetal endocrinology and development - manipulation and adaptation to long-term nutritional and environmental challenges

      REPRODUCTION
    18. McLean, M; Smith, R
      Corticotrophin-releasing hormone and human parturition

      REPRODUCTION
    19. Oehninger, S
      Molecular basis of human sperm-zona pellucida interaction

      CELLS TISSUES ORGANS
    20. Clark, GF; Dell, A; Morris, HR; Patankar, MS; Easton, RL
      The species recognition system: A new corollary for the human fetoembryonic defense system hypothesis

      CELLS TISSUES ORGANS
    21. Bocci, G; Fasciani, A; Danesi, R; Viacava, P; Genazzani, AR; Del Tacca, M
      In-vitro evidence of autocrine secretion of vascular endothelial growth factor by endothelial cells from human placental blood vessels

      MOLECULAR HUMAN REPRODUCTION
    22. Dhara, S; Lalitkumar, PGL; Sengupta, J; Ghosh, D
      Immunohistochemical localization of insulin-like growth factors I and II at the primary implantation site in the Rhesus monkey

      MOLECULAR HUMAN REPRODUCTION
    23. Helske, S; Vuorela, P; Carpen, O; Hornig, C; Weich, H; Halmesmaki, E
      Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies

      MOLECULAR HUMAN REPRODUCTION
    24. Lash, G; MacPherson, A; Liu, D; Smith, D; Charnock-Jones, S; Baker, P
      Abnormal fetal growth is not associated with altered chorionic villous expression of vascular endothelial growth factor mRNA

      MOLECULAR HUMAN REPRODUCTION
    25. Islami, D; Chardonnens, D; Campana, A; Bischof, P
      Comparison of the effects of GnRH-I and GnRH-II on HCG synthesis and secretion by first trimester trophoblast

      MOLECULAR HUMAN REPRODUCTION
    26. Okoko, JB; Wesumperuma, HL; Hart, CA
      The influence of prematurity and low birthweight on transplacental antibody transfer in a rural West African population

      TROPICAL MEDICINE & INTERNATIONAL HEALTH
    27. Shulman, CE; Marshall, T; Dorman, EK; Bulmer, JN; Cutts, F; Peshu, N; Marsh, K
      Malaria in pregnancy: adverse effects on haemoglobin levels and birthweight in primigravidae and multigravidae

      TROPICAL MEDICINE & INTERNATIONAL HEALTH
    28. Faiz, AS; Demissie, K; Ananth, CV; Rhoads, GG
      Risk of abruptio placentae by region of birth and residence among African-American women in the USA

      ETHNICITY & HEALTH
    29. Cook, JL; Keith, BA; White, NM; Randall, CL
      Physiological concentrations of nicotine do not affect prostacyclin, thromboxane or PGE production from perfused human umbilical veins

      ADDICTION BIOLOGY
    30. Fadok, VA; Xue, D; Henson, P
      If phosphatidylserine is the death knell, a new phosphatidylserine-specific receptor is the bellringer

      CELL DEATH AND DIFFERENTIATION
    31. Gluckman, E; Rocha, V; Chevret, S
      Results of unrelated umbilical cord blood hematopoietic stem cell transplant

      TRANSFUSION CLINIQUE ET BIOLOGIQUE
    32. Setzer, RW; Lau, C; Mole, ML; Copeland, MF; Rogers, JM; Kavlock, RJ
      Toward a biologically based dose-response model for developmental toxicityof 5-fluorouracil in the rat: A mathematical construct

      TOXICOLOGICAL SCIENCES
    33. Achyuthan, KE; Achyuthan, AM
      Comparative enzymology, biochemistry and pathophysiology of human exo-alpha-sialidases (neuraminidases)

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
    34. Thompson, MB; Speake, BK; Russell, KJ; McCartney, RJ
      Utilisation of lipids, protein, ions and energy during embryonic development of Australian oviparous skinks in the genus Lampropholis

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
    35. Aronow, BJ; Richardson, BD; Handwerger, S
      Microarray analysis of trophoblast differentiation: gene expression reprogramming in key gene function categories

      PHYSIOLOGICAL GENOMICS
    36. Lange, K
      Regulation of glucose uptake in differentiated cells

      FRONTIERS IN BIOSCIENCE
    37. Magee, JF
      Investigation of stillbirth

      PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
    38. Klein, AK; Patel, DD; Gooding, ME; Sempowski, GD; Chen, BJ; Liu, CX; Kurtzberg, J; Haynes, BF; Chao, NJ
      T-cell recovery in adults and children following umbilical cord blood transplantation

      BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
    39. Barker, JN; Martin, PL; Coad, JE; DeFor, T; Trigg, ME; Kurtzberg, J; Weisdorf, DJ; Wagner, JE
      Low incidence of Epstein-Barr virus-associated posttransplantation lymphoproliferative disorders in 272 unrelated-donor umbilical cord blood transplant recipients

      BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
    40. Dame, L; Sugarman, J
      Blood money: Ethical and legal implications of treating cord blood as property

      JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
    41. Munzer, SR; Smith, FO
      Limited property rights in umbilical cord blood for transplantation and research

      JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
    42. Laml, T; Hartmann, BW; Ruecklinger, E; Preyer, O; Soeregi, G; Wagenbichler, P
      Maternal serum leptin concentrations do not correlate with cord blood leptin concentrations in normal pregnancy

      JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
    43. Leung, EHL; Leung, PCK; Auersperg, N
      Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen

      IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
    44. Ramirez-Bergeron, DL; Simon, MC
      Hypoxia-inducible factor and the development of stem cells of the cardiovascular system

      STEM CELLS
    45. Rossmanith, T; Schroder, B; Bug, G; Muller, P; Klenner, T; Knaus, R; Hoelzer, D; Ottmann, OG
      Interleukin 3 improves the ex vivo expansion of primitive human cord bloodprogenitor cells and maintains the engraftment potential of SCID repopulating cells

      STEM CELLS
    46. Russo, J; Hu, YF; Silva, IDCG; Russo, IH
      Cancer risk related to mammary gland structure and development

      MICROSCOPY RESEARCH AND TECHNIQUE
    47. Ulven, SM; Gundersen, TE; Sakhi, AK; Glover, JC; Blomhoff, R
      Quantitative axial profiles of retinoic acid in the embryonic mouse spinalcord: 9-cis retinoic acid only detected after all-trans-retinoic acid levels are super-elevated experimentally

      DEVELOPMENTAL DYNAMICS
    48. Keller-Wood, M; Wood, CE
      Pituitary-adrenal physiology during pregnancy

      ENDOCRINOLOGIST
    49. Balaram, P; John, M; Enose, S; Symaladevi, PK
      Demonstration of TGF-alpha-EGFR and EGF-EGFR autocrine loops and their relation to proliferation in complete hydatidiform moles (CHM)

      INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
    50. Horowitz, IR; Cho, C; Song, M; Flowers, LC; Santanam, N; Parthasarathy, S; Ramachandran, S
      Increased glycodelin levels in gynecological malignancies

      INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
    51. Markert, UR; Chaouat, G
      Biological activity of the suppressor cells inducer factor secreted by theJeg-3 choriocarcinoma cell line

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    52. Freeman, JL; Rhyne, PW; Dean, DO; Beard, GA; Doellgast, GJ
      Isolation of antibody to human placental alkaline phosphatase (PLAP) from extracts of human placentae

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    53. Peyman, JA
      Mammalian expression cloning of two human trophoblast suppressors of majorhistocompatibility complex genes

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    54. Zenclussen, AC; Gentile, T; Kortebani, G; Mazzolli, A; Margni, R
      Asymmetric antibodies and pregnancy

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    55. Grasso, G; Massai, L; Migliaccio, P; Picciolini, E; Muscettola, M
      Plasma antiviral activity and interferon-gamma production by superantigen-stimulated lymphocytes during normal human pregnancy

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    56. Hambartsoumian, E; Srivastava, RK; Seibel, MM
      Differential expression and regulation of inducible nitric oxide synthase (iNOS) mRNA in human trophoblasts in vitro

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    57. Patten, KF; Mathur, SB; Roudebush, WE
      Immunologic detection of placental lactogen during pregnancy in a mouse model: A preliminary report

      AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
    58. Gartner, CA; Thompson, SJ; Rettie, AE; Nelson, SD
      Human aromatase in high yield and purity by perfusion chromatography and its characterization by difference spectroscopy and mass spectrometry

      PROTEIN EXPRESSION AND PURIFICATION
    59. Leibovich, H; Raver, N; Herman, A; Gregoraszczuk, EL; Gootwine, E; Gertler, A
      Large-scale preparation of recombinant ovine prolactin and determination of its in vitro and in vivo activity

      PROTEIN EXPRESSION AND PURIFICATION
    60. Marino, VJ; Sterin-Prync, AE; Carbonetto, CH; Roguin, LP
      Conformational and sequential epitopes on the human granulocyte-colony stimulating factor molecule (hg-CSF) and their role in binding to human placenta receptors

      CYTOKINE
    61. Seppala, M; Koistinen, H; Koistinen, R
      Glycodelins

      TRENDS IN ENDOCRINOLOGY AND METABOLISM
    62. Hoppe, CC; Walters, MC
      Bone marrow transplantation in sickle cell anemia

      CURRENT OPINION IN ONCOLOGY
    63. Szafranska, B; Miura, R; Ghosh, D; Ezashi, T; Xie, SC; Roberts, RM; Green, JA
      Gene for porcine pregnancy-associated glycoprotein 2 (poPAG2): Its structural organization and analysis of its promoter

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    64. Kwon, JY; McAndrew, BJ; Penman, DJ
      Cloning of brain aromatase gene and expression of brain and ovarian aromatase genes during sexual differentiation in genetic male and female Nile tilapia Oreochromis niloticus

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    65. Dutta, B; Ain, R; Seshagiri, PB; Karande, AA
      Differential influence of recombinant non-glycosylated and glycosylated glycodelin on human sperm function: comparative studies with hamster spermatozoa

      REPRODUCTION FERTILITY AND DEVELOPMENT
    66. Yamamasu, S; Nakai, Y; Nishio, J; Hyun, Y; Honda, KI; Hirai, K; Ishiko, O; Ogita, S
      Conservative management of placental polyp with oral administration of methotrexate

      ONCOLOGY REPORTS
    67. Harpold, TL; Wang, MY; McComb, JG; Monforte, HL; Levy, ML; Reinisch, JF
      Maternal lung adenocarcinoma metastatic to the scalp of a fetus - Case report

      PEDIATRIC NEUROSURGERY
    68. Sanz, R; Lorda-Sanchez, I; Fernandez-Moya, JM; Cifuentes-Sulzberger, S; de Alba, MR; Gonzalez-Gonzalez, MC; Ibanez, MA; Robledo, M; Ayuso, C; Ramos, C
      Chromosomal mosaicism for isochromosome 11q confined to CVS direct preparations

      FETAL DIAGNOSIS AND THERAPY
    69. Miller, RI; Stephan, MJ; Hume, RF; Walker, WO; Kelly, P; Calhoun, BC; Hoeldtke, NJ; Hayden, JE; Martin, LS
      Extreme elevation of maternal serum alpha-fetoprotein associated with mosaic trisomy 8 in a liveborn

      FETAL DIAGNOSIS AND THERAPY
    70. Stipoljev, F; Latin, V; Kos, M; Miskovic, B; Kurjak, A
      Correlation of confined placental mosaicism with fetal intrauterine growthretardation - A case control study of placentas at delivery

      FETAL DIAGNOSIS AND THERAPY
    71. Nikkels, PGJ; van Gemert, MJC; Briet, JW
      Late onset of discordant growth in a monochorionic twin pregnancy: Vascular anastomoses determine fetal growth pattern and not placental sharing

      FETAL DIAGNOSIS AND THERAPY
    72. Kojima, K; Suzuki, Y; Makino, A; Murakami, I; Suzumori, K
      A case of massive subchorionic thrombohematoma diagnosed by ultrasonography and magnetic resonance imaging

      FETAL DIAGNOSIS AND THERAPY
    73. Randal, M; Kossiakoff, AA
      The structure and activity of a monomeric interferon-gamma :alpha-chain receptor signaling complex

      STRUCTURE
    74. Bussolati, O; Dall'Asta, V; Franchi-Gazzola, R; Sala, R; Rotoli, BM; Visigalli, R; Casado, J; Lopez-Fontanals, M; Pastor-Anglada, M; Gazzola, GC
      The role of system A for neutral amino acid transport in the regulation ofcell volume

      MOLECULAR MEMBRANE BIOLOGY
    75. Makikallio, K; Tekay, A; Jouppila, P
      Effects of bleeding on uteroplacental, umbilicoplacental and yolk-sac hemodynamics in early pregnancy

      ULTRASOUND IN OBSTETRICS & GYNECOLOGY
    76. Oppenheimer, L; Holmes, P; Simpson, N; Dabrowski, A
      Diagnosis of low-lying placenta: can migration in the third trimester predict outcome?

      ULTRASOUND IN OBSTETRICS & GYNECOLOGY
    77. Ghourab, S
      Third-trimester transvaginal ultrasonography in placenta previa: does the shape of the lower placental edge predict clinical outcome?

      ULTRASOUND IN OBSTETRICS & GYNECOLOGY
    78. Hafner, F; Schuchter, K; Van Leeuwen, M; Metzenbauer, M; Dillinger-Paller, B; Phillip, K
      Three-dimensional sonographic volumetry of the placenta and the fetus between weeks 15 and 17 of gestation

      ULTRASOUND IN OBSTETRICS & GYNECOLOGY
    79. Duley, L; Henderson-Smart, D; Knight, M; King, J
      Antiplatelet drugs for prevention of pre-eclampsia and its consequences: systematic review

      BRITISH MEDICAL JOURNAL
    80. Liao, QK; Kong, PA; Gao, J; Li, FY; Qian, ZM
      Expression of ferritin receptor in placental microvilli membrane in pregnant women with different iron status at mid-term gestation

      EUROPEAN JOURNAL OF CLINICAL NUTRITION
    81. Firan, M; Bawdon, R; Radu, C; Ober, RJ; Eaken, D; Antohe, F; Ghetie, V; Ward, ES
      The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

      INTERNATIONAL IMMUNOLOGY
    82. Thomas, JL; Mason, JI; Blanco, G; Veisaga, ML
      The engineered, cytosolic form of human type I 3 beta-hydroxysteroid dehydrogenase/isomerase: purification, characterization and crystallization

      JOURNAL OF MOLECULAR ENDOCRINOLOGY
    83. Botella-Estrada, R; Malet, G; Revert, F; Dasi, F; Crespo, A; Sanmartin, O; Guillen, C; Alino, SF
      Antitumor effect of B16 melanoma cells genetically modified with the angiogenesis inhibitor RNasin

      CANCER GENE THERAPY
    84. van Oel, CJ; Baare, WFC; Pol, HEH; Haag, J; Balazs, J; Dingemans, A; Kahn, RS; Sitskoorn, MM
      Differentiating between low and high susceptibility to schizophrenia in twins: the significance of dermatoglyphic indices in relation to other determinants of brain development

      SCHIZOPHRENIA RESEARCH
    85. Numazawa, M; Satoh, S; Nagaoka, M; Honjo, H; Osawa, Y
      Identification of 16 alpha,19-dihydroxyandrostenedione in the serum of pregnant women by gas chromatography-mass spectrometry

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    86. Numazawa, M; Yoshimura, A; Nagaoka, M
      Gas chromatography-mass spectrometric determination of activity of human placental aromatase using 16 alpha-hydroxyandrostenedione as a substrate

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    87. Numazawa, M; Yamada, K; Nagaoka, M
      19-oxygenation of C-19-steroids with an A, B-ring enone structure, competitive inhibitors of estrogen biosynthesis, with human placental aromatase

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    88. Thein, E; Sevilmis, G; Muenzing, S; Hammer, C; Messmer, K
      Evaluation of a system for the perfusion of isolated, rodent organs

      XENOTRANSPLANTATION
    89. Granger, JP; Alexander, BT; Bennett, WA; Khalil, RA
      Pathophysiology of pregnancy-induced hypertension

      AMERICAN JOURNAL OF HYPERTENSION
    90. Byrne, HM; Chaplain, MAJ; Pettet, GJ; McElwain, DLS
      An analysis of a mathematical model of trophoblast invasion

      APPLIED MATHEMATICS LETTERS
    91. Ohashi, M; Ihira, M; Suzuki, K; Suga, S; Asano, Y; Yoshikawa, T; Saito, Y; Sakui, H
      Transfer of human herpesvirus 6 and 7 antibodies from mothers to their offspring

      PEDIATRIC INFECTIOUS DISEASE JOURNAL
    92. Addis, A; Moretti, ME; Syed, FA; Einarson, TR; Koren, G
      Fetal effects of cocaine: an updated meta-analysis

      REPRODUCTIVE TOXICOLOGY
    93. Doerge, DR; Churchwell, MI; Chang, HC; Newbold, RR; Delclos, KB
      Placental transfer of the soy isoflavone genistein following dietary and gavage administration to Sprague Dawley rats

      REPRODUCTIVE TOXICOLOGY
    94. Iuorno, MJ; Nestler, JE
      Insulin-lowering drugs in polycystic ovary syndrome

      OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA
    95. Yu, LC; Wall, DA; Sandler, E; Chan, KW; Grayson, G; Kletzel, M
      Unrelated cord blood transplant experience by the pediatric blood and marrow transplant consortium

      PEDIATRIC HEMATOLOGY AND ONCOLOGY
    96. Tuxen, MK
      Tumor marker CA125 in ovarian cancer

      JOURNAL OF TUMOR MARKER ONCOLOGY
    97. van Tuinen, M; Hedges, SB
      Calibration of avian molecular clocks

      MOLECULAR BIOLOGY AND EVOLUTION
    98. Fuchs, H; Tauber, R; Gessner, R
      Determination of optimal non-denaturing elution conditions from affinity columns by a solid-phase screen

      BIOTECHNIQUES
    99. Midrio, P; Zadra, N; Grismondi, G; Suma, V; Pitton, MA; Salvadori, S; Gamba, P
      EXIT procedure in a twin gestation and review of the literature

      AMERICAN JOURNAL OF PERINATOLOGY
    100. Gaunt, G; Ramin, K
      Immunological tolerance of the human fetus

      AMERICAN JOURNAL OF PERINATOLOGY


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/11/20 alle ore 03:15:02