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La ricerca find articoli where soggetti phrase all words 'pharmacodynamic' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 413 riferimenti
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    1. Wang, B; Ludden, TM; Cheung, EN; Schwab, GG; Roskos, LK
      Population pharmacokinetic-pharmacodynamic modeling of Filgrastim (r-metHuG-CSF) in healthy volunteers

      JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
    2. Laurin, J; Donati, F; Nekka, F; Varin, F
      Peripheral link model as an alternative for pharmacokinetic-pharmacodynamic modeling of drugs having a very short elimination half-life

      JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
    3. Stein, E
      Results of phase I/II clinical trials with ezetimibe, a novel selective cholesterol absorption inhibitor

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    4. Liao, CM; Lin, MC
      Acute toxicity modeling of rainbow trout and silver sea bream exposed to waterborne metals

      ENVIRONMENTAL TOXICOLOGY
    5. Olliaro, PL; Haynes, RK; Meunier, B; Yuthavong, Y
      Possible modes of action of the artemisinin-type compounds

      TRENDS IN PARASITOLOGY
    6. Quinones-Torrelo, C; Sagrado, S; Villanueva-Camanas, RM; Medina-Hernandez, MJ
      Retention pharmacokinetic and pharmacodynamic parameter relationships of antihistamine drugs using biopartitioning micellar chromatography

      JOURNAL OF CHROMATOGRAPHY B
    7. van Leeuwen, IMM; Zonneveld, C
      From exposure to effect: a comparison of modeling approaches to chemical carcinogenesis

      MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
    8. Wellington, K; Perry, CM
      Venlafaxine extended-release - A review of its use in the management of major depression

      CNS DRUGS
    9. MacGowan, A; Rogers, C; Bowker, K
      In vitro models, in vivo models, and pharmacokinetics: What can we learn from in vitro models?

      CLINICAL INFECTIOUS DISEASES
    10. Hocht, C; Opezzo, JAW; Gorzalczany, SB; Priano, RM; Bramuglia, GF; Taira, CA
      Pharmacokinetic and pharmacodynamic alterations of methyldopa in rats withaortic coarctation. A study using microdialysis

      PHARMACOLOGICAL RESEARCH
    11. Koutsoviti-Papadopoulou, M; Nikolaidis, E; Kounenis, G
      Biphenylacetic acid enhances the antagonistic action of fluoroquinolones on the GABA(A)-mediated responses of the isolated guinea-pig ileum

      PHARMACOLOGICAL RESEARCH
    12. Koutsoviti-Papadopoulou, M; Nikolaidis, E; Batzias, GC; Kounenis, G
      Synergistic and antagonistic pharmacodynamic interaction between ranitidine and cisapride: A study on the isolated rabbit intestine

      PHARMACOLOGICAL RESEARCH
    13. De Sarro, A; De Sarro, G
      Adverse reactions to fluoroquinolones. An overview on mechanistic aspects

      CURRENT MEDICINAL CHEMISTRY
    14. Sun, L; Lau, CE
      Arteriovenous serum cocaine concentration difference after intravenous bolus injection and constant-rate infusions: relation to pharmacodynamic estimates in rats

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    15. Aarons, L; Karlsson, MO; Mentre, F; Rombout, F; Steimer, JL; van Peer, A
      Role of modelling and simulation in Phase I drug development

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    16. Ohno, Y; Yamada, Y; Usui, T; Takahashi, K; Tsuchiya, F; Ohtani, H; Sato, H; Sawada, Y; Iga, T
      Pharmacokinetic and pharmacodynamic analysis of the antihypercalcemic effect of incadronate disodium in rats

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    17. Wu, G
      Sensitivity analysis of pharmacodynamic parameters in pharmacodynamic models

      EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
    18. Zuideveld, KP; Maas, HJ; Treijtel, N; Hulshof, J; Van der Graaf, PH; Peletier, LA; Danhof, M
      A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia

      AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
    19. Wikell, C; Kugelberg, FC; Hjorth, S; Apelqvist, G; Bengtsson, F
      Effect of halving the dose of venlafaxine to adjust for putative pharmacokinetic and pharmacodynamic changes in an animal model of chronic hepatic encephalopathy

      CLINICAL NEUROPHARMACOLOGY
    20. Blin, O; Simon, N; Jouve, E; Habib, M; Gayraud, D; Durand, A; Bruguerolle, B; Pisano, P
      Pharmacokinetic and pharmacodynamic analysis of sedative and amnesic effects of lorazepam in healthy volunteers

      CLINICAL NEUROPHARMACOLOGY
    21. Donnelly, R; Seale, JP
      Clinical pharmacokinetics of inhaled budesonide

      CLINICAL PHARMACOKINETICS
    22. Boulton, DW; Fawcett, JP
      The pharmacokinetics of levosalbutamol - What are the clinical implications?

      CLINICAL PHARMACOKINETICS
    23. Lotsch, J; Muth-Selbach, U; Tegeder, I; Brune, K; Geisslinger, G
      Simultaneous fitting of R- and S-ibuprofen plasma concentrations after oral administration of the racemate

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    24. Brynne, L; McNay, JL; Schaefer, HG; Swedberg, K; Wiltse, CG; Karlsson, MO
      Pharmacodynamic models for the cardiovascular effects of moxonidine in patients with congestive heart failure

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    25. Cullberg, M; Eriksson, UG; Larsson, M; Karlsson, MO
      Population modelling of the effect of inogatran, at thrombin inhibitor, onex vivo coagulation time (APTT) in healthy subjects and patients with coronary artery disease

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    26. Jungkunz, G; Kuss, HJ; Gsell, W
      Long-term effects of tricyclic antidepressants on norepinephrine kinetics in humans

      JOURNAL OF NEURAL TRANSMISSION
    27. White, RL
      What in vitro models of infection can and cannot do

      PHARMACOTHERAPY
    28. Thervet, E; Anglicheau, D; Legendre, C
      Pharmacology of mycophenolate mofetil: recent insights and clinical consequences

      NEPHROLOGIE
    29. Gobburu, JVS; Jusko, WJ
      Role of dosage regimen in controlling indirect pharmacodynamic responses

      ADVANCED DRUG DELIVERY REVIEWS
    30. Filler, G; Lepage, N; Delisle, B; Mai, I
      Effect of cyclosporine on mycophenolic acid area under the concentration-time curve in pediatric kidney transplant recipients

      THERAPEUTIC DRUG MONITORING
    31. Wyska, E; Jusko, WJ
      Approaches to pharmacokinetic/pharmacodynamic modeling during pregnancy

      SEMINARS IN PERINATOLOGY
    32. Bakker-Woudenberg, IAJM; Ten Kate, MT; Guo, L; Working, P; Mouton, JW
      Improved efficacy of ciprofloxacin administered in polyethylene glycol-coated liposomes for treatment of Klebsiella pneumoniae pneumonia in rats

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    33. Aviles, P; Pateman, A; Roman, RS; Guillen, MJ; De las Heras, FG; Gargallo-Viola, D
      Animal pharmacokinetics and interspecies scaling of sordarin derivatives following intravenous administration

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    34. Andersen, ME; Dennison, JE
      Mode of action and tissue dosimetry in current and future risk assessments

      SCIENCE OF THE TOTAL ENVIRONMENT
    35. Penttila, J; Helminen, A; Luomala, K; Scheinin, H
      Pharmacokinetic-pharmacodynamic model for the anticholinergic effect of glycopyrrolate

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    36. Cunha, BA
      Intravenous to oral antibiotic switch therapy

      DRUGS OF TODAY
    37. Kozusko, F; Chen, PH; Grant, SG; Day, BW; Panetta, JC
      A mathematical model of in vitro cancer cell growth and treatment with theantimitotic agent curacin A

      MATHEMATICAL BIOSCIENCES
    38. 't Hoen, PAC; Bijsterbosch, MK; Van Berkel, TJC; Vermeulen, NPE; Commandeur, JNM
      Midazolam is a phenobarbital-like cytochrome P450 inducer in rats

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    39. Desta, Z; Soukhova, N; Morocho, AM; Flockhart, DA
      Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: Major role of CYP3A

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    40. Gentilini, A; Rossoni-Gerosa, M; Frei, CW; Wymann, R; Morari, M; Zbinden, AM; Schnider, TW
      Modeling and closed-loop control of hypnosis by means of bispectral index (BIS) with isoflurane

      IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
    41. Fluker, M; Grifo, J; Leader, A; Levy, M; Meldrum, D; Muasher, SJ; Rinehart, J; Rosenwaks, Z; Scott, RT; Schoolcraft, W; Shapiro, DB
      Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation

      FERTILITY AND STERILITY
    42. Vis, P; Della Pasqua, O; Kruk, M; Martin, D; Mocaer, E; Danhof, M; Jochemsen, R
      Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-MT1A receptor agonist, using a behavioural model in rats

      EUROPEAN JOURNAL OF PHARMACOLOGY
    43. Wong, SHY
      Therapeutic drug monitoring for immunosuppressants

      CLINICA CHIMICA ACTA
    44. Wang, MD; Zhu, D; Backstrom, T; Wahlstrom, G
      The interaction between ethanol and pregnanolone at induction of anaesthesia investigated with a threshold method in male rats

      BRITISH JOURNAL OF PHARMACOLOGY
    45. Serkova, N; Jacobsen, W; Niemann, CU; Litt, L; Benet, LZ; Leibfritz, D; Christians, U
      Sirolimus, but not the structurally related RAD (everolimus), enhances thenegative effects of cyclosporine on mitochondrial metabolism in the rat brain

      BRITISH JOURNAL OF PHARMACOLOGY
    46. Bennett, J; Wakefield, J
      Errors-in-variables in joint population pharmacokinetic/pharmacodynamic modeling

      BIOMETRICS
    47. Schultz, P; Ibsen, M; Ostergaard, D; Skovgaard, LT
      Onset and duration of action of rocuronium - from tracheal intubation, through intense block to complete recovery

      ACTA ANAESTHESIOLOGICA SCANDINAVICA
    48. Simpao, A; Sun, L; Falk, JL; Lau, CE
      Spontaneous activity as a contingency-controlled behavior within an operant context: alprazolam concentration-effect relations after subcutaneous administration in rats

      PSYCHOPHARMACOLOGY
    49. Wang, Q; Simpao, A; Sun, L; Falk, JL; Lau, CE
      Contribution of the active metabolite, norcocaine, to cocaine's effects after intravenous and oral administration in rats: pharmacodynamics

      PSYCHOPHARMACOLOGY
    50. Budde, K; Glander, P; Bauer, S; Braun, K; Waiser, J; Fritsche, L; Mai, I; Roots, I; Neumayer, HH
      Pharmacodynamic monitoring of mycophenolate mofetil

      CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    51. Laizure, SC; Cyr, M
      Nefazodone: An update

      INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE
    52. Price, RN
      Artemisinin drugs: novel antimalarial agents

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    53. Hoffman, HL; Ernst, EJ; Klepser, ME
      Novel triazole antifungal agents

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    54. Balfour, JAB; Jarvis, B
      Venlafaxine extended-release - A review of its clinical potential in the management of generalised anxiety disorder

      CNS DRUGS
    55. Dooley, M; Lamb, HM
      Donepezil - A review of its use in Alzheimer's disease

      DRUGS & AGING
    56. Vandenberg, CM; Kazmi, Y; Jann, MW
      Cholinesterase inhibitors for the treatment of Alzheimer's disease in the elderly

      DRUGS & AGING
    57. Esposito, S; Noviello, S; Ianniello, F
      Bactericidal activity of moxifloxacin compared to grepafloxacin and clarithromycin against Streptococcus pneumoniae and Streptococcus pyogenes investigated using an in vitro pharmacodynamic model

      JOURNAL OF CHEMOTHERAPY
    58. Fuentes, F; Sevillano, D; Balcabao, IP; Gomez-Lus, ML; Prieto, J
      In vitro activity of clarithromycin against penicillin-susceptible and penicillin-resistant strains of Streptococcus pneumoniae in a pharmacodynamic simulation model

      JOURNAL OF CHEMOTHERAPY
    59. Cazzola, M; Di Perna, F; Boveri, B; Di Marco, F; Diamare, F; Centanni, S
      Interrelationship between the pharmacokinetics and pharmacodynamics of cefaclor advanced formulation in patients with acute exacerbations of chronic bronchitis

      JOURNAL OF CHEMOTHERAPY
    60. Gao, L; Ramzan, I; Baker, B
      Neuromuscular paralysis as pharmacodynamic probe to assess organ function during liver transplantation

      JOURNAL OF CLINICAL ANESTHESIA
    61. de Lange, ECM; Marchand, S; van den Berg, DJ; van der Sandt, ICJ; de Boer, AG; Delon, A; Bouquet, S; Couet, W
      In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    62. Suzuki, T; Shimizu, R; Suganuma, T; Nishino, J; Tomono, K; Hanano, M; Watanabe, J
      Pharmacokinetic/pharmacodynamic relationship of eptazocine, a narcotic-antagonist analgesic, in rats

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    63. Garrido, M; Gubbens-Stibbe, J; Tukker, E; Cox, E; von Frijtag, J; Kunzel, D; IJzerman, A; Danhof, M; van der Graaf, PH
      Pharmacokinetic-pharmacodynamic analysis of the EEG effect of alfentanil in rats following beta-funaltrexamine-induced mu-opioid receptor "knockdown"in vivo

      PHARMACEUTICAL RESEARCH
    64. Sheiner, LB; Steimer, JL
      Pharmacokinetic/pharmacodynamic modeling in drug development

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    65. Goh, BC; Fleming, GF; Janisch, L; Vogelzang, NJ; Stadler, WM; Ratain, MJ
      Development of a schedule-dependent population pharmacodynamic model for rhizoxin without quantitation of plasma concentrations

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    66. Millenbaugh, NJ; Wientjes, MG; Au, JLS
      A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    67. Williams, PJ; Ette, EI
      The role of population pharmacokinetics in drug development in light of the Food and Drug Administration's 'Guidance for Industry: Population pharmacokinetics'

      CLINICAL PHARMACOKINETICS
    68. van den Bongard, HJGD; Mathot, RAA; Beijnen, JH; Schellens, JHM
      Pharmacokinetically guided administration of chemotherapeutic agents

      CLINICAL PHARMACOKINETICS
    69. Rousseau, A; Marquet, P; Debord, J; Sabot, C; Lachatre, G
      Adaptive control methods for the dose individualisation of anticancer agents

      CLINICAL PHARMACOKINETICS
    70. Nolting, A; Abramowitz, W
      Lack of interaction between citalopram and the CYP3A4 substrate triazolam

      PHARMACOTHERAPY
    71. Ramirez, AMD; Delgadillo, GPH; Martinez, RV; Reval, MID; Lopez-Munoz, FJ
      Analgesic efficacy of the combination metamizol plus morphine after subchronic treatment in rats

      DRUG DEVELOPMENT RESEARCH
    72. Preskorn, SH; Greenblatt, DJ; Harvey, AT
      Lack of effect of sertraline on the pharmacokinetics of alprazolam

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    73. Hassan, PC; Sproule, BA; Naranjo, CA; Herrmann, N
      Dose-response evaluation of the interaction between sertraline and alprazolam in vivo

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    74. Borm, G; Mannaerts, B
      Treatment with the gonadotrophin-releasing hormone antagonist ganirelix inwomen undergoing ovarian stimulation with recombinant follicle stimulatinghormone is effective, safe and convenient: results of a controlled, randomized, multicentre trial

      HUMAN REPRODUCTION
    75. Simonsen, LE; Wahlby, U; Sandstrom, M; Freijs, A; Karlsson, MO
      Haematological toxicity following different dosing schedules of 5-fluorouracil and epirubicin in rats

      ANTICANCER RESEARCH
    76. Emilien, G; van Meurs, W; Maloteaux, JM
      The dose-response relationship in Phase I clinical trials and beyond: use,meaning, and assessment

      PHARMACOLOGY & THERAPEUTICS
    77. Comets, E; Pousset, F; Mentre, F; Diquet, B; Ankri, A; Mallet, A; Lechat, P
      Prediction of fluindione maintenance dosage hampered by large intraindividual variability

      THERAPEUTIC DRUG MONITORING
    78. Albrecht, W; Storck, M; Pfetsch, E; Martin, W; Abendroth, D
      Development and application of a high-performance liquid chromatography-based assay for determination of the activity of inosine 5 '-monophosphate dehydrogenase in whole blood and isolated mononuclear cells

      THERAPEUTIC DRUG MONITORING
    79. Jelliffe, R; Schumitzky, A; Van Guilder, M
      Population pharmacokinetics/pharmacodynamics modeling: Parametric and nonparametric methods

      THERAPEUTIC DRUG MONITORING
    80. Furberg, CD
      Class effects and evidence-based medicine

      CLINICAL CARDIOLOGY
    81. Gabrielsson, K; Jusko, WJ; Alari, L
      Modeling of dose-response-time data: Four examples of estimating the turnover parameters and generating kinetic functions from response profiles

      BIOPHARMACEUTICS & DRUG DISPOSITION
    82. Abdelaziz, MM; Khair, OA; Devalia, JL
      The potential of active metabolites of antihistamines in the management ofallergic disease

      ALLERGY
    83. Samama, MM; Gerotziafas, GT
      Comparative pharmacokinetics of LMWHs

      SEMINARS IN THROMBOSIS AND HEMOSTASIS
    84. Hochhaus, G; Barrett, JS; Derendorf, H
      Evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20th century

      JOURNAL OF CLINICAL PHARMACOLOGY
    85. Derendorf, H; Lesko, LJ; Chaikin, P; Colburn, WA; Lee, P; Miller, R; Powell, R; Rhodes, G; Stanski, D; Venitz, J
      Pharmacokinetic/pharmacodynamic modeling in drug research and development

      JOURNAL OF CLINICAL PHARMACOLOGY
    86. Chaikin, P; Rhodes, GR; Bruno, R; Rohatagi, S; Natarajan, C
      Pharmacokinetics/pharmacodynamics in drug development: An industrial perspective

      JOURNAL OF CLINICAL PHARMACOLOGY
    87. Pukrittayakamee, S; Chantra, A; Simpson, JA; Vanijanonta, S; Clemens, R; Looareesuwan, S; White, NJ
      Therapeutic responses to different antimalarial drugs in vivax malaria

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    88. Ernst, EJ; Klepser, ME; Pfaller, MA
      Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    89. Hershberger, E; Rybak, MJ
      Activities of trovafloxacin, gatifloxacin, clinafloxacin, sparfloxacin, levofloxacin, and ciprofloxacin against penicillin-resistant Streptococcus pneumoniae in an in vitro infection model

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    90. Thomas, RS; Conolly, RB; Gustafson, DL; Long, ME; Benjamin, SA; Yang, RSH
      A physiologically based pharmacodynamic analysis of hepatic foci within a medium-term liver bioassay using pentachlorobenzene as a promoter and diethylnitrosamine as an initiator

      TOXICOLOGY AND APPLIED PHARMACOLOGY
    91. Derendorf, H; Hochhaus, G; Krishnaswami, S; Meibohm, B; Mollmann, H
      Optimized therapeutic ratio of inhaled corticosteroids using retrometabolism

      PHARMAZIE
    92. Schmaldienst, S; Traunmuller, F; Burgmann, H; Rosenkranz, AR; Thalhammer-Scherrer, R; Horl, WH; Thalhammer, F
      Multiple-dose pharmacokinetics of cefepime in long-term hemodialysis with high-flux membranes

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    93. Hoshen, MB; Na-Bangchang, K; Stein, WD; Ginsburg, H
      Mathematical modelling of the chemotherapy of Plasmodium falciparum malaria with artesunate: postulation of 'dormancy', a partial cytostatic effect of the drug, and its implication for treatment regimens

      PARASITOLOGY
    94. Dupuis, A; Caillaud, A; Pariat, C; Courtois, P; Couet, W; Bouquet, S
      Comparative cerebrospinal fluid diffusion of imipenem and meropenem in rats

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    95. Sun, L; Lau, CE
      Intravenous and oral clozapine pharmacokinetics, pharmacodynamics, and concentration-effect relations: acute tolerance

      EUROPEAN JOURNAL OF PHARMACOLOGY
    96. Deckers, CLP; Czuczwar, SJ; Hekster, YA; Keyser, A; Kubova, H; Meinardi, H; Patsalos, PN; Renier, WO; Van Rijn, CM
      Selection of antiepileptic drug polytherapy based on mechanisms of action:The evidence reviewed

      EPILEPSIA
    97. Gilbert, DL; Sallee, FR; Sine, L; Sethuraman, G
      Behavioral and hormonal effects of low-dose pergolide in children and adolescents with Gilles de la Tourette's syndrome

      CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
    98. Iliadis, A; Barbolosi, D
      Optimizing drug regimens in cancer chemotherapy by an efficacy-toxicity mathematical model

      COMPUTERS AND BIOMEDICAL RESEARCH
    99. Millan, O; Oppenheimer, F; Brunet, M; Vilardell, J; Rojo, I; Vives, J; Martorell, J
      Assessment of mycophenolic acid-induced immunosuppression: A new approach

      CLINICAL CHEMISTRY
    100. James, IT
      Are commercial immunoassay kits satisfactory for measuring pharmacodynamicand surrogate endpoints?

      CHROMATOGRAPHIA


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Documento generato il 04/06/20 alle ore 12:55:17