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Physical stabilization of DNA-based therapeutics
DRUG DISCOVERY TODAY
Porous chitin matrices for tissue engineering: Fabrication and in vitro cytotoxic assessment
JOURNAL OF POLYMER RESEARCH-TAIWAN
Development of formulations that enhance physical stability of viral vectors for gene therapy
GENE THERAPY
Exergy analysis for the freezing stage of the freeze drying process
DRYING TECHNOLOGY
Lyophilized lecithin based oil-water microemulsions as a new and low toxicdelivery system for amphotericin B
PHARMACEUTICAL RESEARCH
Use of pure t-butanol as a solvent for freeze-drying: a case study
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Dry powder inhalation of liposomal Ketotifen fumarate: formulation and characterization
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Development of a lyophilized formulation for (R,R)-formoterol (L)-tartrate
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Storage and lyophilization effects of extracts of Cynara cardunculus on the degradation of ovine and caprine caseins
FOOD CHEMISTRY
Theoretical approaches to physical transformations of active pharmaceutical ingredients during manufacturing processes
ADVANCED DRUG DELIVERY REVIEWS
Factors affecting short-term and long-term stabilities of proteins
ADVANCED DRUG DELIVERY REVIEWS
Excipients activate peroxidases in specific but not in non-specific reactions in organic solvents
BIOTECHNOLOGY LETTERS
Double-blind, placebo-controlled food challenge with apple
ALLERGY
Comparison of different culture media and storage temperatures for the long-term preservation of Streptococcus pneumoniae in the tropics
BULLETIN OF THE WORLD HEALTH ORGANIZATION
Faecal elastase-1: Lyophilization of stool samples prevents false low results in diarrhoea
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Continuous measurement of drying rate of crystalline and amorphous systemsduring freeze-drying using an in situ microbalance technique
JOURNAL OF PHARMACEUTICAL SCIENCES
The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature-controlled shelf
JOURNAL OF PHARMACEUTICAL SCIENCES
Annealing to optimize the primary drying rate, reduce freezing-induced drying rate heterogeneity, and determine T-g ' in pharmaceutical lyophilization
JOURNAL OF PHARMACEUTICAL SCIENCES
A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody
JOURNAL OF PHARMACEUTICAL SCIENCES
Maintenance of nonviral vector particle size during the freezing step of the lyophilization process is insufficient for preservation of activity: Insight from other structural indicators
JOURNAL OF PHARMACEUTICAL SCIENCES
The effects of tween 20 and sucrose on the stability of anti-L-selectin during lyophilization and reconstitution
JOURNAL OF PHARMACEUTICAL SCIENCES
Modulation of antigenicity related to changes in antibody flexibility uponlyophilization
JOURNAL OF MOLECULAR BIOLOGY
Functional integrity and structural stability of freeze-dried ectomycorrhizal fungi established through viability assays
CANADIAN JOURNAL OF MICROBIOLOGY
Towards more active biocatalysts in organic media: Increasing the activityof salt-activated enzymes
BIOTECHNOLOGY AND BIOENGINEERING
Effect of crown ethers on structure, stability, activity, and enantioselectivity of subtilisin Carlsberg in organic solvents
BIOTECHNOLOGY AND BIOENGINEERING
Variations in the enantioselectivity of salt-activated subtilisin induced by lyophilization
BIOTECHNOLOGY AND BIOENGINEERING
Maintenance of quaternary structure in the frozen state stabilizes lactatedehydrogenase during freeze-drying
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Fourier transform infrared spectrometric analysis of protein conformation:Effect of sampling method and stress factors
ANALYTICAL BIOCHEMISTRY
Properties of human free apolipoprotein(a) and lipoprotein(a) after eitherfreezing or lyophilization in the presence and absence of cryopreservatives
ANALYTICAL BIOCHEMISTRY
Phase separation of polyelectrolytes and non-ionic polymers in frozen solutions
PCCP PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Retention of enzyme activity following freeze-drying the mycelium of ectomycorrhizal isolates: part II. Enzymes acting upon carbon compounds
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
Lyophilized platelets: continued development
TRANSFUSION SCIENCE
Lyophilization of Tc-99m-HYNIC labeled PEG-liposomes
JOURNAL OF LIPOSOME RESEARCH
Effects of lyophilization on the physical characteristics and chemical stability of amorphous quinapril hydrochloride
PHARMACEUTICAL RESEARCH
Formation and isolation of spherical fine protein microparticles through lyophilization of protein-poly(ethylene glycol) aqueous mixture
PHARMACEUTICAL RESEARCH
Freeze-concentration separates proteins and polymer excipients into different amorphous phases
PHARMACEUTICAL RESEARCH
The formation and mechanism of multimerization in a freeze-dried peptide
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Influence of different parameters on reconstitution of lyophilized SLN
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Optimization of the formulation and characterization of the physicochemical properties of the novel platelet-activating factor receptor antagonist E5880
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Possibility of wound dressing using poly(L-leucine)/poly(ethylene glycol)/poly(L-leucine) triblock copolymer
BIOMATERIALS
Prediction of the preservation of freeze-dried cucumber mosaic virus
BIOTECHNOLOGY LETTERS
The biochemistry of botulinum toxin type B
NEUROLOGY
The activity of the carbon metabolism enzymes in Chromatium minutissimum after long-term storage
MICROBIOLOGY
Comparative investigation of different methods of storage of lactic acid bacteria
MICROBIOLOGY
Lyophilization of cationic lipid-protamine-DNA (LPD) complexes
JOURNAL OF PHARMACEUTICAL SCIENCES
Stabilization and preservation of Lactobacillus acidophilus in saccharide matrices
CRYOBIOLOGY
Effect of polymer excipients on the enzyme activity of lyophilized bilirubin oxidase and beta-galactosidase formulations
CHEMICAL & PHARMACEUTICAL BULLETIN
Intracellular function in rehydrated lyophilized platelets
BRITISH JOURNAL OF HAEMATOLOGY
Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesis
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Physicochemical evaluation of a stability-driven approach to drug entrapment in regular and in surface-modified liposomes
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Synthesis, characterization and properties of PZT materials modified with Nd. Part I. Processing of precursor powders.
AFINIDAD
Physicochemical differences in dehydrated Saccharomyces boulardii yeast asa function of the dehydration process
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
Effect of different surface active agents on the crystallinity of lyophilized diltiazem hydrochloride
STP PHARMA SCIENCES
Thermal properties and processing of (sulfobutylether)(7m)-beta-cyclodextrin as a freeze-drying excipient in pharmaceutical formulations
STP PHARMA SCIENCES
X-ray crystal structures of a severely desiccated protein
PROTEIN SCIENCE
Freeze-drying vegetative mycelium of Laccaria fraterna and its subsequent regeneration
BIOTECHNOLOGY TECHNIQUES
Formulation, stability, and delivery of live attenuated vaccines for humanuse
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS
Estimation of the effect of product shrinkage on the drying times, heat input and condenser load of the primary and secondary drying stages of the lyophilization process in vials
DRYING TECHNOLOGY
Development of a mathematical model for the water distribution in freeze-dried solids
PHARMACEUTICAL RESEARCH
Various methods of conserving yeast on the test bench
MONATSSCHRIFT FUR BRAUWISSENSCHAFT
Development of a lyophilized kit formulation for labeling of DNA probes with Tc-99m
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Short term stability of freeze-dried, lyoprotected liposomes
JOURNAL OF CONTROLLED RELEASE
Protein stabilising effect of polyethyleneimine
JOURNAL OF BIOTECHNOLOGY
Porous chitosan scaffolds for tissue engineering
BIOMATERIALS
Increase of catalytic activity of alpha-chymotrypsin in organic solvent byco-lyophilization with cyclodextrins
BIOTECHNOLOGY LETTERS
Entomopathogenic fungal (hyphomycetes) collection: Assessment of conidial viability
PESQUISA AGROPECUARIA BRASILEIRA
Increased extraction efficiency of acetonitrile/water mixtures for explosives determination in plant tissues
CHEMOSPHERE
Preservation of tropical wood-inhabiting basidiomycetes
MYCOLOGIA
Effect of heat shock or cold shock treatment on the resistance of Lactococcus lactis to freezing and lyophilization
CRYOBIOLOGY
Fourier-transform infrared spectroscopy study of dehydrated lipases from Candida antarctica B and Pseudomonas cepacia
BIOTECHNOLOGY AND BIOENGINEERING
Protein formulation and lyophilization cycle design: Prevention of damage due to freeze-concentration induced phase separation
BIOTECHNOLOGY AND BIOENGINEERING
Optimizing the salt-induced activation of enzymes in organic solvents: Effects of lyophilization time and water content
BIOTECHNOLOGY AND BIOENGINEERING
Application of a thermodynamic model to the prediction of phase separations in freeze-concentrated formulations for protein lyophilization
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Susceptibility of rhDNase I to glycation in the dry-powder state
ANALYTICAL CHEMISTRY
Lyophilized Streptomyces aureofaciens spores
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
STORAGE OF FUNGI USING STERILE DISTILLED WATER OR LYOPHILIZATION - COMPARISON AFTER 12 YEARS
Mycoses
THE REDISPERSIBILITY AND PHYSICOCHEMICAL PROPERTIES OF FREEZE-DRIED COLLOIDAL MICROGELS
Colloids and surfaces. A, Physicochemical and engineering aspects
OPTIMAL-CONTROL OF THE PRIMARY AND SECONDARY DRYING STAGES OF BULK SOLUTION FREEZE-DRYING IN TRAYS
Drying technology
STABILIZATION OF LACTATE-DEHYDROGENASE FOLLOWING FREEZE-THAWING AND VACUUM-DRYING IN THE PRESENCE OF TREHALOSE AND BORATE
Pharmaceutical research
FRACTAL AND REACTIVE DIMENSIONS OF SOME URSODEOXYCHOLIC ACID SALTS
International journal of pharmaceutics
WATER SORPTION BEHAVIOR OF LYOPHILIZED PROTEIN-SUGAR SYSTEMS AND IMPLICATIONS FOR SOLID-STATE INTERACTIONS
International journal of pharmaceutics
THE EFFECT OF LYOPHILIZED SOIL EXTRACTS O N GERMINATION, LENGTH OF HYPOCOTYL AND ROOT OF TRIFOLIUM-PRATENSE, CV VESNA AND FESTUCA-ARUNDINACEA, CV KORA
Rostlinna vyroba
HIGH-TEMPERATURE CONJUGATION OF PROTEINS WITH CARBOHYDRATES
Glycoconjugate journal
DRUG RETENTION AND STABILITY OF SOLID LIPID NANOPARTICLES CONTAINING AZIDOTHYMIDINE PALMITATE AFTER AUTOCLAVING, STORAGE AND LYOPHILIZATION
Journal of microencapsulation
INFLUENCE OF SEDIMENT PRESERVATION ON TOTAL MERCURY AND METHYLMERCURYANALYSES
Water, air and soil pollution
RETENTION OF THE VIABILITY AND PHYSIOLOGICAL-PROPERTIES OF BIFIDOBACTERIA DURING STORAGE BY CRYOPRESERVATION AND LYOPHILIZATION
Microbiology (New York)
CHARACTERIZATION OF STARKING APPLE POLYPHENOLOXIDASE
Journal of the Science of Food and Agriculture
MODELING OF THE PRIMARY AND SECONDARY DRYING STAGES OF THE FREEZE-DRYING OF PHARMACEUTICAL PRODUCTS IN VIALS - NUMERICAL RESULTS OBTAINED FROM THE SOLUTION OF A DYNAMIC AND SPATIALLY MULTIDIMENSIONAL LYOPHILIZATION MODEL FOR DIFFERENT OPERATIONAL POLICIES
Biotechnology and bioengineering
TESTING FOR DIFFUSION LIMITATIONS IN SALT-ACTIVATED ENZYME CATALYSTS OPERATING IN ORGANIC-SOLVENTS
Biotechnology and bioengineering
ON ENZYMATIC-ACTIVITY IN ORGANIC-SOLVENTS AS A FUNCTION OF ENZYME HISTORY
Biotechnology and bioengineering
DEVELOPMENT OF REFERENCE AND TEST MATERIALS FOR ORGANIC CONTAMINANTS IN WATER
Analyst
STABILITY OF THIOTEPA (LYOPHILIZED) IN 0.9-PERCENT SODIUM-CHLORIDE INJECTION
American journal of health-system pharmacy
MATHEMATICAL-MODELING OF THE PRIMARY AND SECONDARY DRYING STAGES OF BULK SOLUTION FREEZE-DRYING IN TRAYS - PARAMETER-ESTIMATION AND MODEL DISCRIMINATION BY COMPARISON OF THEORETICAL RESULTS WITH EXPERIMENTAL-DATA
Drying technology
RATIONAL DESIGN OF STABLE LYOPHILIZED PROTEIN FORMULATIONS - SOME PRACTICAL ADVICE
Pharmaceutical research
EFFECT OF GLASS-TRANSITION TEMPERATURE ON THE STABILITY OF LYOPHILIZED FORMULATIONS CONTAINING A CHIMERIC THERAPEUTIC MONOCLONAL-ANTIBODY
Pharmaceutical research
DEVELOPMENT OF A NOVEL BIOACTIVE FORMULATION OF VASOACTIVE-INTESTINAL-PEPTIDE IN STERICALLY STABILIZED LIPOSOMES
Pharmaceutical research
REAL-TIME IN-SITU MONITORING OF LYSOZYME DURING LYOPHILIZATION USING INFRARED-SPECTROSCOPY - DEHYDRATION STRESS IN THE PRESENCE OF SUCROSE
Pharmaceutical research
STABILIZATION OF FULLY ACTIVE CHYMOPAPAIN BY LYOPHILIZATION
International journal of pharmaceutics
MOISTURE ABSORPTION AND DESORPTION OF DIFFERENT RUBBER LYOPHILIZATIONCLOSURES
International journal of pharmaceutics
FREEZE-DRYING OF DRUG-FREE AND DRUG-LOADED SOLID LIPID NANOPARTICLES (SLN)
International journal of pharmaceutics