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A novel mechanism of antibiotic resistance: study of the complex state of peptides with bacterial Staphylococcus aureus ribosomes
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE II FASCICULE C-CHIMIE
ABT-773: a new ketolide antibiotic
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Telithromycin: a new ketolide antimicrobial for treatment of respiratory tract infections
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Uptake and intracellular activity of ketolide HMR 3647 in human phagocyticand non-phagocytic cells
CLINICAL MICROBIOLOGY AND INFECTION
Safeguarding future antimicrobial options: strategies to minimize resistance
CLINICAL MICROBIOLOGY AND INFECTION
Pharmacodynamic and pharmacokinetic considerations in antimicrobial selection: focus on telithromycin
CLINICAL MICROBIOLOGY AND INFECTION
Immunomodulation by macrolide antibiotics
JOURNAL OF CHEMOTHERAPY
Macrolides: structures and microbial targets
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
In vitro activity of ABT-773 versus macrolides and quinolones against resistant respiratory tract pathogens
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
In vitro activity of pristinamycine against Streptococcus pneumoniae.
PATHOLOGIE BIOLOGIE
Antibacterial activity of telithromycin (HMR 3647) in relation to in vitrosimulated human plasma kinetics
Journal of antimicrobial chemotherapy
In vitro activity of midecamycin diacetate against Mycoplasma pneumoniae and Chlamydia pneumoniae
Journal of antimicrobial chemotherapy
HMR 3647 human-like treatment of experimental pneumonia due to penicillin-resistant and erythromycin-resistant Streptococcus pneumoniae
Journal of antimicrobial chemotherapy
In vitro activity of telithromycin against Spanish Streptococcus pneumoniae isolates with characterized macrolide resistance mechanisms
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Uptake, transport, and delivery of antimicrobial agents by human polymorphonuclear neutrophils
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Postantibiotic effects of ABT-773 and amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S-pyogenes
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
In vitro activity of ABT-773 against Legionella pneumophila, its pharmacokinetics in guinea pigs, and its use to treat guinea pigs with L. pneumophila pneumonia
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Cellular uptake of two fluoroketolides, HMR 3562 and HMR 3787, by human polymorphonuclear neutrophils in vitro
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Pharmacodynamics of telithromycin in vitro against respiratory tract pathogens
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Telithromycin
DRUGS
Inhibitory and bactericidal effects of telithromycin (HMR 3647, RU 56647) and five comparative antibiotics, used singly and in combination, against vancomycin-resistant and vancomycin-susceptible enterococci
CHEMOTHERAPY
Dissociation-equilibrium constant and bound conformation for weak antibiotic binding interaction with different bacterial ribosomes
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
Recent developments in the area of macrolide antibiotics
EXPERT OPINION ON THERAPEUTIC PATENTS
Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides
GENE
Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against Gram-positive clinical isolates in Japan
Journal of antimicrobial chemotherapy
Antibacterial effect of telithromycin (HMR 3647) and comparative antibiotics against intracellular Legionella pneumophila
Journal of antimicrobial chemotherapy
Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates
Journal of antimicrobial chemotherapy
Activities of antimicrobial agents against intracellular pneumococci
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin, and pristinamycin in Streptococcus pneumoniae
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Bactericidal activities of antibiotics against intracellular Francisella tularensis
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
What's new in the antibiotic pipeline
CURRENT OPINION IN MICROBIOLOGY
Macrolide and ketolide antibiotic separation by reversed phase high performance liquid chromatography
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Superiority of 11,12 carbonate macrolide antibiotics as inhibitors of translation and 50S ribosomal subunit formation in Staphylococcus aureus cells
CURRENT MICROBIOLOGY
In-vitro activity of HMR 3647 against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and beta-haemolytic streptococci
Journal of antimicrobial chemotherapy
The bactericidal activities of HMR 3004, HMR 3647 and erythromycin againstGram-positive bacilli and development of resistance
Journal of antimicrobial chemotherapy
Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Activity of HMR 3647 compared to those of six compounds against 235 strains of Enterococcus faecalis
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
RECENT DEVELOPMENTS WITH MACROLIDE ANTIBIOTICS
Expert opinion on therapeutic patents
IN-VITRO ACTIVITY OF HMR-3647 AGAINST ANAEROBIC-BACTERIA
Journal of chemotherapy
In-vitro antimicrobial activity of HMR 3004 (RU 64004) against erythromycin A-sensitive and -resistant Corynebacterium spp. isolated from clinical specimens
Journal of antimicrobial chemotherapy
ACTIVITY OF HMR-3647 COMPARED TO THOSE OF 5 AGENTS AGAINST HAEMOPHILUS-INFLUENZAE AND MORAXELLA-CATARRHALIS BY MIC DETERMINATION AND TIME-KILL ASSAY
Antimicrobial agents and chemotherapy
Immunomodulating effects of HMR 3004 on pulmonary inflammation caused by heat-killed Streptococcus pneumoniae in mice
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
A GENE-CLUSTER FOR MACROLIDE ANTIBIOTIC BIOSYNTHESIS IN STREPTOMYCES-VENEZUELAE - ARCHITECTURE OF METABOLIC DIVERSITY
Proceedings of the National Academy of Sciences of the United Statesof America
ANTIBACTERIAL AGENTS
Medecine et maladies infectieuses