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La ricerca find articoli where soggetti phrase all words 'horseradish peroxidase' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 4230 riferimenti
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    1. Bukowska, D
      Morphological evidence for secondary vestibular afferent connections to the dorsal cochlear nucleus in the rabbit

      CELLS TISSUES ORGANS
    2. Rai, GP; Sakai, S; Florez, AM; Mogollon, L; Hager, LP
      Directed evolution of chloroperoxidase for improved epoxidation and chlorination catalysis

      ADVANCED SYNTHESIS & CATALYSIS
    3. Ferapontova, EE; Grigorenko, VG; Egorov, AM; Borchers, T; Ruzgas, T; Gorton, L
      Direct electron transfer in the system gold electrode-recombinant horseradish peroxidases

      JOURNAL OF ELECTROANALYTICAL CHEMISTRY
    4. Long, DD; Marx, KA; Zhou, T
      Amperometric hydrogen peroxide sensor electrodes coated with electropolymerized tyrosine derivative and phenolic films

      JOURNAL OF ELECTROANALYTICAL CHEMISTRY
    5. Tatsuma, T; Ogawa, T; Sato, R; Oyama, R
      Peroxidase-incorporated sulfonated polyaniline-polycation complexes for electrochemical sensing of H2O2

      JOURNAL OF ELECTROANALYTICAL CHEMISTRY
    6. Kievit, O; Brudvig, GW
      Direct electrochemistry of photosystem I

      JOURNAL OF ELECTROANALYTICAL CHEMISTRY
    7. Matsuo, R; Yamauchi, Y; Kobashi, M; Funahashi, M; Mitoh, Y; Adachi, A
      Role of parabrachial nucleus in submandibular salivary secretion induced by bitter taste stimulation in rats

      AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
    8. Buck, HD; Caous, CA; Lindsey, CJ
      Projections of the paratrigeminal nucleus to the ambiguus, rostroventrolateral and lateral reticular nuclei, and the solitary tract

      AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
    9. Yavo, B; Brunetti, IL; da Fonseca, LM; Catalani, LH; Campa, A
      Selective activity of butyrylcholinesterase in serum by a chemiluminescentassay

      LUMINESCENCE
    10. Kuroda, N; Murasaki, N; Wada, M; Nakashima, K
      Application of an enhanced luminol chemiluminescence reaction using 4-[4,5-di(2-pyridyl)-1H-imidazol-2-yl]phenylboronic acid to photographic detection of horseradish peroxidase on a membrane

      LUMINESCENCE
    11. Galban, J; Andreu, Y; Sierra, JF; de Marcos, S; Castillo, JR
      Intrinsic fluorescence of enzymes and fluorescence of chemically modified enzymes for analytical purposes: a review

      LUMINESCENCE
    12. Miyahara, T; Tokita, Y; Nakatsuji, H
      SAC/SAC-CI study of the ground, excited, and ionized states of cytochromesP450CO

      JOURNAL OF PHYSICAL CHEMISTRY B
    13. Schweitzer-Stenner, R; Bigman, D
      Electronic and vibronic contributions to the band splitting in optical spectra of heme proteins

      JOURNAL OF PHYSICAL CHEMISTRY B
    14. Schaffer, WM; Bronnikova, TV; Olsen, LF
      Nonlinear dynamics of the peroxidase-oxidase reaction. II. Compatibility of an extended model with previously reported model-data correspondences

      JOURNAL OF PHYSICAL CHEMISTRY B
    15. Bronnikova, TV; Schaffer, WM; Olsen, LF
      Nonlinear dynamics of the peroxidase-oxidase reaction: I. Bistability and bursting oscillations at low enzyme concentrations

      JOURNAL OF PHYSICAL CHEMISTRY B
    16. Coen, JJF; Smith, AT; Candeias, LP; Oakes, J
      New insights into mechanisms of dye degradation by one-electron oxidation processes

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    17. Kulys, J; Deussen, HJ; Krikstopaitis, K; Lolck, R; Schneider, P; Ziemys, A
      N-arylhydroxamic acids as novel oxidoreductase substrates

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    18. McClung, JR; Shall, MS; Goldberg, SJ
      Motoneurons of the lateral and medial rectus extraocular muscles in squirrel monkey and cat

      CELLS TISSUES ORGANS
    19. Ogino, H; Ishikawa, H
      Enzymes which are stable in the presence of organic solvents

      JOURNAL OF BIOSCIENCE AND BIOENGINEERING
    20. Takikawa, H; Sano, N; Takada, Y; Toda, A; Tanaka, H; Takamori, Y
      Effect of bile acids on biliary excretion of cyclosporin A in the rat

      HEPATOLOGY RESEARCH
    21. Azevedo, AM; Prazeres, DMF; Cabral, JMS; Fonseca, LP
      Stability of free and immobilised peroxidase in aqueous-organic solvents mixtures

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    22. Budde, CL; Beyer, A; Munir, IZ; Dordick, JS; Khmelnitsky, YL
      Enzymatic nitration of phenols

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    23. Piccolo, A; Conte, P; Cozzolino, A; Paci, M
      Combined effects of an oxidative enzyme and dissolved humic substances on C-13-labelled 2,4-D herbicide as revealed by high-resolution C-13 NMR spectroscopy

      JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    24. Harris, DL; Loew, GH
      Proximal ligand effects on electronic structure and spectra of compound I of peroxidases

      JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
    25. Terner, J; Gold, A; Weiss, R; Mandon, D; Trautwein, AX
      Symmetry states of metalloporphyrin pi-cation radicals, models for peroxidase compound I

      JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
    26. Levy, I; Shoseyov, O
      Expression, refolding and indirect immobilization of horseradish peroxidase (HRP) to cellulose via a phage-selected peptide and cellulose-binding domain (CBD)

      JOURNAL OF PEPTIDE SCIENCE
    27. Gutierrez-Correa, J; Fairlamb, AH; Stoppani, AOM
      Trypanosoma cruzi trypanothione reductase is inactivated by peroxidase-generated phenothiazine cationic radicals

      FREE RADICAL RESEARCH
    28. Miura, T; Muraoka, S; Fujimoto, Y
      Phenylbutazone radicals inactivate creatine kinase

      FREE RADICAL RESEARCH
    29. Qian, X; Bauer, RA; Xu, HS; Lloyd, RV
      In situ hybridization detection of calcitonin mRNA in routinely fixed, paraffin-embedded tissue sections: A comparison of different types of probes combined with tyramide signal amplification

      APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
    30. Medyantseva, EP; Khaldeeva, EV; Budnikov, GK
      Immunosensors in biology and medicine: Analytical capabilities, problems, and prospects

      JOURNAL OF ANALYTICAL CHEMISTRY
    31. Ibrahim, MS; Ali, HI; Taylor, KE; Biswas, N; Bewtra, JK
      Enzyme-catalyzed removal of phenol from refinery wastewater: Feasibility studies

      WATER ENVIRONMENT RESEARCH
    32. Taniai, T; Sukuragawa, A; Okutani, T
      Fluorometric determination of ethanol in liquor samples by flow-injection analysis using an immobilized enzyme-reactor column with packing prepared by coupling alcohol oxidase and peroxidase onto chitosan beads

      JOURNAL OF AOAC INTERNATIONAL
    33. Ueno, M; Sakamoto, H; Kanenishi, K; Onodera, M; Akiguchi, I; Hosokawa, M
      Ultrastructural and permeability features of microvessels in the periventricular area of senescence-accelerated mice (SAM)

      MICROSCOPY RESEARCH AND TECHNIQUE
    34. Messlinger, K; Ellrich, J
      Meningeal nociception: Electrophysiological studies related to headache and referred pain

      MICROSCOPY RESEARCH AND TECHNIQUE
    35. Distler, C; Hoffmann, KP
      Cortical input to the nucleus of the optic tract and dorsal terminal nucleus (NOT-DTN) in macaques: a retrograde tracing study

      CEREBRAL CORTEX
    36. Hamasaki, T; Goto, S; Nishikawa, S; Ushio, Y
      Early-generated preplate neurons in the developing telencephalon: Inward migration into the developing striatum

      CEREBRAL CORTEX
    37. Gole, A; Dash, C; Soman, C; Sainkar, SR; Rao, M; Sastry, M
      On the preparation, characterization, and enzymatic activity of fungal protease-gold colloid bioconjugates

      BIOCONJUGATE CHEMISTRY
    38. Schumacher, JT; Hecht, HJ; Dengler, U; Reichelt, J; Bilitewski, U
      Direct electron transfer observed for peroxidase to screen-printed graphite electrodes

      ELECTROANALYSIS
    39. Wang, BQ; Li, B; Cheng, GJ; Dong, SJ
      Acid-stable amperometric soybean peroxidase biosensor based on a self-gelatinizable grafting copolymer of polyvinyl alcohol and 4-vinylpyridine

      ELECTROANALYSIS
    40. Rosatto, SS; Neto, GD; Kubota, LT
      Effect of DNA on the peroxidase based biosensor for phenol determination in waste waters

      ELECTROANALYSIS
    41. Yabuki, S; Mizutani, F; Hirata, Y
      Glucose-sensing electrode based on glucose oxidase-attached polyion complex membrane containing peroxidase and ferrocene

      ELECTROANALYSIS
    42. Imabayashi, S; Kong, YT; Watanabe, M
      Amperometric biosensor for polyphenol based on horseradish peroxidase immobilized on gold electrodes

      ELECTROANALYSIS
    43. Gaspar, S; Zimmermann, H; Gazaryan, I; Csoregi, E; Schuhmann, W
      Hydrogen peroxide biosensors based on direct electron transfer from plant peroxidases immobilized on self-assembled thiol-monolayer modified gold electrodes

      ELECTROANALYSIS
    44. Zhang, YL; Jin, SZ; Zhang, CX; Shen, HX
      Studies on electrocatalytical kinetic behavior of horseradish peroxidase and assay for hydrogen peroxide at salt bridge supported bilayer lipid membrane

      ELECTROANALYSIS
    45. Chen, X; Wang, BQ; Dong, SJ
      Amperometric biosensor for hydrogen peroxide based on sol-gel/hydrogel composite thin film

      ELECTROANALYSIS
    46. Ferri, T; Maida, S; Poscia, A; Santucci, R
      A glucose biosensor based on electro-enzyme catalyzed oxidation of glucoseusing a HRP-GOD layered assembly

      ELECTROANALYSIS
    47. Azevedo, AM; Fonseca, LP; Graham, D; Cabral, JMS; Prazeres, DMF
      Behaviour of horseradish peroxidase in AOT reversed micelles

      BIOCATALYSIS AND BIOTRANSFORMATION
    48. Tarasevich, MR; Bogdanovskaya, VA; Fridman, VA; Kuznetsova, LN
      Kinetics and mechanism of the H2O2 electroreduction on the peroxidase-promoted electrodes

      RUSSIAN JOURNAL OF ELECTROCHEMISTRY
    49. Edwards, AM; Silva, E
      Effect of visible light on selected enzymes, vitamins and amino acids

      JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
    50. Arnaldos, TL; Ferrer, MA; Munoz, R; Calderon, AA
      Purification and stability of a basic peroxidase from strawberry callus culture

      PLANT PHYSIOLOGY AND BIOCHEMISTRY
    51. Zhao, XL; Smartt, CT; Li, JY; Christensen, BM
      Aedes aegypti peroxidase gene characterization and developmental expression

      INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
    52. Mazarakis, ND; Azzouz, M; Rohll, JB; Ellard, FM; Wilkes, FJ; Olsen, AL; Carter, EE; Barber, RD; Baban, DF; Kingsman, SM; Kingsman, AJ; O'Malley, K; Mitrophanous, KA
      Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery

      HUMAN MOLECULAR GENETICS
    53. Mariotti, M; Gritti, I; Mancia, M
      The synchronising influence of Substantia Innominata on the thalamus of the cat

      JOURNAL OF SLEEP RESEARCH
    54. Henriksen, A; Mirza, O; Indiani, C; Teilum, K; Smulevich, G; Welinder, KG; Gajhede, M
      Structure of soybean seed coat peroxidase: A plant peroxidase with unusualstability and haem-apoprotein interactions

      PROTEIN SCIENCE
    55. Arnao, MB; Cano, A; Alcolea, JF; Acosta, M
      Estimation of free radical-quenching activity of leaf pigment extracts

      PHYTOCHEMICAL ANALYSIS
    56. Bolm, C; Beckmann, O; Kuhn, T; Palazzi, C; Adam, W; Rao, PB; Saha-Moller, CR
      Influence of hydroperoxides on the enantioselectivity of metal-catalyzed asymmetric Baeyer-Villiger oxidation and epoxidation with chiral ligands

      TETRAHEDRON-ASYMMETRY
    57. Ferapontova, EE; Grigorenko, VG; Egorov, AM; Borchers, T; Ruzgas, T; Gorton, L
      Mediatorless biosensor for H2O2 based on recombinant forms of horseradish peroxidase directly adsorbed on polycrystalline gold

      BIOSENSORS & BIOELECTRONICS
    58. Wu, ZY; Wang, BQ; Cheng, ZL; Yang, XR; Dong, SJ; Wang, EK
      A facile approach to immobilize protein for biosensor: self-assembled supported bilayer lipid membranes on glassy carbon electrode

      BIOSENSORS & BIOELECTRONICS
    59. Kuznetsov, BA; Shumakovich, GP; Koroleva, OV; Yaropolov, AI
      On applicability of laccase as label in the mediated and mediatorless electroimmunoassay: effect of distance on the direct electron transfer between laccase and electrode

      BIOSENSORS & BIOELECTRONICS
    60. Chen, XH; Xie, H; Kong, JL; Deng, JQ
      Characterization for didodecyldimethylammonium bromide liquid crystal filmentrapping catalase with enhanced direct electron transfer rate

      BIOSENSORS & BIOELECTRONICS
    61. Guillaume, A; Pelisson, D
      Gaze shifts evoked by electrical stimulation of the superior colliculus inthe head-unrestrained cat. II. Effect of muscimol inactivation of the caudal fastigial nucleus

      EUROPEAN JOURNAL OF NEUROSCIENCE
    62. Ni, ZG; Gao, DM; Bouali-Benazzouz, R; Benabid, AL; Benazzouz, A
      Effect of microiontophoretic application of dopamine on subthalamic nucleus neuronal activity in normal rats and in rats with unilateral lesion of the nigrostriatal pathway

      EUROPEAN JOURNAL OF NEUROSCIENCE
    63. Haj-Dahmane, S
      D-2-like dopamine receptor activation excites rat dorsal raphe 5-HT neurons in vitro

      EUROPEAN JOURNAL OF NEUROSCIENCE
    64. Tham, TN; Lazarini, F; Franceschini, IA; Lachapelle, F; Amara, A; Dubois-Dalcq, M
      Developmental pattern of expression of the alpha chemokine stromal cell-derived factor 1 in the rat central nervous system

      EUROPEAN JOURNAL OF NEUROSCIENCE
    65. Haase, A; Stern, M; Wachtler, K; Bicker, G
      A tissue-specific marker of Ecdysozoa

      DEVELOPMENT GENES AND EVOLUTION
    66. Yeh, HC; Wang, JS; Su, YO; Lin, WY
      Stopped-flow kinetic study of the H2O2 oxidation of substrates catalyzed by microperoxidase-8

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    67. Watanabe, Y
      Alternatives to the oxoferryl porphyrin cation radical as the proposed reactive intermediate of cytochrome P450: two-electron oxidized Fe(III) porphyrin derivatives

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    68. Ghosh, A; Steene, E
      High-valent transition metal centers and noninnocent ligands in metalloporphyrins and related molecules: a broad overview based on quantum chemical calculations

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    69. Hiner, ANP; Hernandez-Ruiz, J; Rodriguez-Lopez, JN; Arnao, MB; Varon, R; Garcia-Canovas, F; Acosta, M
      The inactivation of horseradish peroxidase isoenzyme A2 by hydrogen peroxide: an example of partial resistance due to the formation of a stable enzyme intermediate

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    70. Herold, S; Rehmann, FJK
      Kinetic and mechanistic studies of the reactions of nitrogen monoxide and nitrite with ferryl myoglobin

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    71. Wright, PJ; English, AM
      Buffer-anion-dependent Ca2+ leaching from horseradish peroxidase at low pH

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    72. Egawa, T; Proshlyakov, DA; Miki, H; Makino, R; Ogura, T; Kitagawa, T; Ishimura, Y
      Effects of a thiolate axial ligand on the pi ->pi* electronic states of oxoferryl porphyrins: a study of the optical and resonance Raman spectra of compounds I and II of chloroperoxidase

      JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
    73. Erro, ME; Lanciego, JL; Arribas, J; Gimenez-Amaya, JM
      Striatal input from the ventrobasal complex of the rat thalamus

      HISTOCHEMISTRY AND CELL BIOLOGY
    74. Alibardi, L
      Fine structure and neurotransmitter cytochemistry of neurons in the rat ventral cochlear nucleus projecting to the ipsilateral dorsal cochlear nucleus

      ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
    75. Yadav, JS; Nanda, S; Rao, AB
      Soybean lipoxygenase and horseradish peroxidase catalysed asymmetric oxidation-reduction sequence for the synthesis of chiral (Z,E) diene-diols

      SYNLETT
    76. Lobnik, A; Cajlakovic, M
      Sol-gel based optical sensor for continuous determination of dissolved hydrogen peroxide

      SENSORS AND ACTUATORS B-CHEMICAL
    77. Pandey, PC; Upadhyay, S; Tiwari, I; Tripathi, VS
      An ormosil-based peroxide biosensor - a comparative study on direct electron transport from horseradish peroxidase

      SENSORS AND ACTUATORS B-CHEMICAL
    78. Li, BX; Zhang, ZJ; Jin, Y
      Chemiluminescence flow biosensor for hydrogen peroxide with immobilized reagents

      SENSORS AND ACTUATORS B-CHEMICAL
    79. Perez, EF; Neto, GD; Kubota, LT
      Bi-enzymatic amperometric biosensor for oxalate

      SENSORS AND ACTUATORS B-CHEMICAL
    80. Hilgetag, CC; Grant, S
      Uniformity and specificity of long-range corticocortical connections in the visual cortex of the cat

      NEUROCOMPUTING
    81. Akita, M; Tsutsumi, D; Kobayashi, M; Kise, H
      Structural change and catalytic activity of horseradish peroxidase in oxidative polymerization of phenol

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    82. Kusaba-Nakayama, M; Ki, M; Kawada, E; Sato, M; Ikeda, I; Mochizuki, T; Imaizumi, K
      Intestinal absorbability of wheat allergens, subunits of a wheat alpha-amylase inhibitor, expressed by bacteria

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    83. Misaki, R; Kimura, Y; Fujiyama, K; Seki, T
      Glycoproteins secreted from suspension-cultured tobacco BY2 cells have distinct glycan structures from intracellular glycoproteins

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    84. Hassouna, E; Yamamoto, M; Imagawa, T; Uehara, M
      Distribution of reticulocerebellar neurons in chicken reticular formation

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    85. Gooding, JJ; Erokhin, P; Losic, D; Yang, WR; Policarpio, V; Liu, JQ; Ho, FM; Situmorang, M; Hibbert, DB; Shapter, JG
      Parameters important in fabricating enzyme electrodes using self-assembledmonolayers of alkanethiols

      ANALYTICAL SCIENCES
    86. McHaffie, JG; Thomson, CM; Stein, BE
      Corticotectal and corticostriatal projections from the frontal eye fields of the cat: an anatomical examination using WGA-HRP

      SOMATOSENSORY AND MOTOR RESEARCH
    87. Duhrsen, U; Martinez, T; Vohwinkel, G; Ergun, S; Sun, L; McMahon, G; Durig, J; Hossfeld, DK; Fielder, W
      Effects of vascular endothelial and platelet-derived growth factor receptor inhibitors on long-term cultures from normal human bone marrow

      GROWTH FACTORS
    88. Chen, XY; Feng-Chen, KC; Chen, L; Stark, DM; Wolpaw, JR
      Short-term and medium-term effects of spinal cord tract transections on soleus H-reflex in freely moving rats

      JOURNAL OF NEUROTRAUMA
    89. Gill, I
      Bio-doped nanocomposite polymers: Sol-gel bioencapsulates

      CHEMISTRY OF MATERIALS
    90. Mody, N; Parhami, F; Sarafian, TA; Demer, LL
      Oxidative stress modulates osteoblastic differentiation of vascular and bone cells

      FREE RADICAL BIOLOGY AND MEDICINE
    91. van Reyk, DM; King, NJC; Dinauer, MC; Hunt, NH
      The intracellular oxidation of 2 ',7 '-dichlorofluorescin in murine T lymphocytes

      FREE RADICAL BIOLOGY AND MEDICINE
    92. Reuse, MH; Reuss, S
      Nitric oxide synthase neurons in the rodent spinal cord: distribution, relation to Substance P fibers, and effects of dorsal rhizotomy

      JOURNAL OF CHEMICAL NEUROANATOMY
    93. Zhang, LF; Moritani, M; Honma, S; Yoshida, A; Shigenaga, Y
      Quantitative ultrastructure of slowly adapting lingual afferent terminals in the principal and oral nuclei in the cat

      SYNAPSE
    94. Ni, ZG; Bouali-Benazzouz, R; Gao, DM; Benabid, AL; Benazzouz, A
      Intrasubthalamic injection of 6-hydroxydopamine induces changes in the firing rate and pattern of subthalamic nucleus neurons in the rat

      SYNAPSE
    95. Rosell, A; Gimenez-Amaya, JM
      Double retrograde tracer study of the corticostriatal projections to the cat caudate nucleus

      SYNAPSE
    96. Eppel, GA; Osicka, TM; Pratt, LM; Jablonski, P; Howden, B; Glasgow, EF; Comper, WD
      The return of glomerular filtered albumin to the rat renal vein - The albumin retrieval pathway

      RENAL FAILURE
    97. Ciarimboli, G; Bokenkamp, A; Schurek, HJ; Fels, LM; Kilian, I; Maess, B; Stolte, H
      The "fixed" charge of glomerular capillary wall as determinant of permselectivity

      RENAL FAILURE
    98. Demers, N; Agostinelli, E; Averill-Bates, DA; Fortier, G
      Immobilization of native and poly(ethylene glycol)-treated ('PEGylated') bovine serum amine oxidase into a biocompatible hydrogel

      BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
    99. Gole, A; Dash, C; Ramakrishnan, V; Sainkar, SR; Mandale, AB; Rao, M; Sastry, M
      Pepsin-gold colloid conjugates: Preparation, characterization, and enzymatic activity

      LANGMUIR
    100. Smith, CE; Atchabahian, A; Mackinnon, SE; Hunter, DA
      Development of the blood-nerve barrier in neonatal rats

      MICROSURGERY


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Documento generato il 25/02/20 alle ore 14:56:42