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La ricerca find articoli where soggetti phrase all words 'high-throughput screening' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 127 riferimenti
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    1. Kim, HJ; Lee, HH; Yoo, HD; Lee, JH; Hong, ST
      Development of a solid-phase binding assay and identification of nonpeptide ligands for the FynB Src homology 2 domain

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    2. Schwille, P; Heinze, KG
      Two-photon fluorescence cross-correlation spectroscopy

      CHEMPHYSCHEM
    3. Muller, M; Mathers, TW; Davis, AP
      A new screen for combinatorial catalysis; On-bead testing in agarose gel

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    4. Reetz, MT
      Combinatorial and evolution-based methods in the creation of enantioselective catalysts

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    5. Senkan, S
      Combinatorial heterogeneous catalysis - A new path in an old field

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    6. Rodemerck, U; Wolf, D; Buyevskaya, OV; Claus, P; Senkan, S; Baerns, M
      High-throughput synthesis and screening of catalytic materials - Case study on the search for a low-temperature catalyst for the oxidation of low-concentration propane

      CHEMICAL ENGINEERING JOURNAL
    7. Lentz, O; Qing-Shang, LI; Schwaneberg, U; Lutz-Wahl, S; Fischer, P; Schmid, RD
      Modification of the fatty acid specificity of cytochrome P450BM-3 from Bacillus megaterium by directed evolution: A validated assay

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    8. Jenne, A; Hartig, JS; Piganeau, N; Tauer, A; Samarsky, DA; Green, MR; Davies, J; Famulok, M
      Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology

      NATURE BIOTECHNOLOGY
    9. Bornscheuer, UT
      Directed evolution of enzymes for biocatalytic applications

      BIOCATALYSIS AND BIOTRANSFORMATION
    10. Mikami, K; Korenaga, T; Matsukawa, S; Ding, KL; Long, J
      Engineering chiral catalysts through asymmetric activation and super high throughput screening (SHTS)

      CHINESE JOURNAL OF CHEMISTRY
    11. Zhang, ML; Lorson, CL; Androphy, EJ; Zhou, J
      An in vivo reporter system for measuring increased inclusion of exon 7 in SMN2 mRNA: potential therapy of SMA

      GENE THERAPY
    12. Shaffer, KM; Lin, HJ; Maric, D; Pancrazio, JJ; Stenger, DA; Barker, JL; Ma, W
      The use of GABA(A) receptors expressed in neural precursor cells for cell-based assays

      BIOSENSORS & BIOELECTRONICS
    13. Volland, MAO; Adlhart, C; Kiener, CA; Chen, P; Hofmann, P
      Catalyst screening by electrospray ionization tandem mass spectrometry: Hofmann carbenes for olefin metathesis

      CHEMISTRY-A EUROPEAN JOURNAL
    14. Claus, P; Honicke, D; Zech, T
      Miniaturization of screening devices for the combinatorial development of heterogeneous catalysts

      CATALYSIS TODAY
    15. Snively, CM; Oskarsdottir, G; Lauterbach, J
      Chemically sensitive parallel analysis of combinatorial catalyst libraries

      CATALYSIS TODAY
    16. Reetz, MT; Kuhling, KM; Wilensek, S; Husmann, H; Hausig, UW; Hermes, M
      A GC-based method for high-throughput screening of enantio selective catalysts

      CATALYSIS TODAY
    17. Leach, AR; Green, DVS
      Computational chemistry in lead identification, library design and lead optimisation

      MOLECULAR SIMULATION
    18. Pinder, RM
      On the feasibility of designing new antidepressants

      HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
    19. Abt, M; Lim, Y; Sacks, J; Xie, M; Young, SS
      A sequential approach for identifying lead compounds in large chemical databases

      STATISTICAL SCIENCE
    20. Clark, EA; Fanguy, JC; Henry, CS
      High-throughput multi-analyte screening for renal disease using capillary electrophoresis

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    21. Papac, DI; Shahrokh, Z
      Mass spectrometry innovations in drug discovery and development

      PHARMACEUTICAL RESEARCH
    22. Roy, D; Ducher, F; Laumain, A; Legendre, JY
      Determination of the aqueous solubility of drugs using a convenient 96-well plate-based assay

      DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
    23. Galietta, LVJ; Jayaraman, S; Verkman, AS
      Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    24. Marsh, AE; Mullins, AL; Lakritz, J
      In vitro quantitative analysis of H-3-uracil incorporation by Sarcocytis neurona to determine efficacy of anti-protozoal agents

      VETERINARY PARASITOLOGY
    25. Delagrave, S; Murphy, DJ; Pruss, JLR; Maffia, AM; Marrs, BL; Bylina, EJ; Coleman, WJ; Grek, CL; Dilworth, MR; Yang, MM; Youvan, DC
      Application of a very high-throughput digital imaging screen to evolve theenzyme galactose oxidase

      PROTEIN ENGINEERING
    26. Luciani, N; De Rocquigny, H; Turcaud, S; Romieu, A; Roques, BP
      Highly sensitive and selective fluorescence assays for rapid screening of endothelin-converting enzyme inhibitors

      BIOCHEMICAL JOURNAL
    27. Steff, AM; Fortin, M; Arguin, C; Hugo, P
      Detection of a decrease in green fluorescent protein fluorescence for the monitoring of cell death: An assay amenable to high-throughput screening technologies

      CYTOMETRY
    28. Agrafiotis, DK; Lobanov, VS
      Multidimensional scaling of combinatorial libraries without explicit enumeration

      JOURNAL OF COMPUTATIONAL CHEMISTRY
    29. Crameri, R
      High throughput screening: a rapid way to recombinant allergens

      ALLERGY
    30. Dahmen, S; Brase, S
      Combinatorial methods for the discovery and optimisation of homogeneous catalysts

      SYNTHESIS-STUTTGART
    31. Kariv, I; Cao, H; Oldenburg, KR
      Development of a high throughput equilibrium dialysis method

      JOURNAL OF PHARMACEUTICAL SCIENCES
    32. Reymond, JL
      Exploring biocatalysis using catalytic antibodies

      CHIMIA
    33. Johnsson, A; Byrne, P; de Bruin, R; Weiner, D; Wong, J; Los, G
      Identification of gene clusters differentially expressed during the cellular injury responses (CIR) to cisplatin

      BRITISH JOURNAL OF CANCER
    34. Knaust, RKC; Nordlund, P
      Screening for soluble expression of recombinant proteins in a 96-well format

      ANALYTICAL BIOCHEMISTRY
    35. Farrelly, E; Amaral, MC; Marshall, L; Huang, SG
      A high-throughput assay for mitochondrial membrane potential in permeabilized yeast cells

      ANALYTICAL BIOCHEMISTRY
    36. Zhang, LT; Schwartz, G; O'Donnell, M; Harrison, RK
      Development of a novel helicase assay using electrochemiluminescence

      ANALYTICAL BIOCHEMISTRY
    37. Ninkovic, M; Riester, D; Wirsching, F; Dietrich, R; Schwienhorst, A
      Fluorogenic assay for penicillin G acylase activity

      ANALYTICAL BIOCHEMISTRY
    38. Zheng, W; Carroll, SS; Inglese, J; Graves, R; Howells, L; Strulovici, B
      Miniaturization of a hepatitis C virus RNA polymerase assay using a-102 degrees C cooled CCD camera-based imaging system

      ANALYTICAL BIOCHEMISTRY
    39. Deo, SK; Daunert, S
      Green fluorescent protein mutant as label in homogeneous assays for biomolecules

      ANALYTICAL BIOCHEMISTRY
    40. Rathbone, DL; Ge, Y
      Selectivity of response in fluorescent polymers imprinted with N-1-benzylidene pyridine-2-carboxamidrazones

      ANALYTICA CHIMICA ACTA
    41. Selzer, PM; Brutsche, S; Wiesner, P; Schmid, P; Mullner, H
      Target-based drug discovery for the development of novel antiinfectives

      INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
    42. Mikami, K; Terada, M; Korenaga, T; Matsumoto, Y; Ueki, M; Angelaud, R
      Asymmetric activation

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    43. Bobzin, SC; Yang, ST; Kasten, TP
      Application of liquid chromatography-nuclear magnetic resonance spectroscopy to the identification of natural products

      JOURNAL OF CHROMATOGRAPHY B
    44. Tao, JS; Schimmel, P
      Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    45. Haner, RL; Llanos, W; Mueller, L
      Small volume flow probe for automated direct-injection NMR analysis: Design and performance

      JOURNAL OF MAGNETIC RESONANCE
    46. Emili, AQ; Cagney, G
      Large-scale functional analysis using peptide or protein arrays

      NATURE BIOTECHNOLOGY
    47. Stack, JH; Whitney, M; Rodems, SM; Pollok, BA
      A ubiquitin-based tagging system for controlled modulation of protein stability

      NATURE BIOTECHNOLOGY
    48. Hyde-DeRuyscher, R; Paige, LA; Christensen, DJ; Hyde-DeRuyscher, N; Lim, A; Fredericks, ZL; Kranz, J; Gallant, P; Zhang, J; Rocklage, SM; Fowlkes, DM; Wendler, PA; Hamilton, PT
      Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries

      CHEMISTRY & BIOLOGY
    49. Crespi, CL; Stresser, DM
      Fluorometric screening for metabolism-based drug-drug interactions

      JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
    50. Rodemerck, U; Ignaszewski, P; Lucas, M; Claus, P; Baerns, M
      Parallel synthesis and fast screening of heterogeneous catalysts

      TOPICS IN CATALYSIS
    51. Reetz, MT; Jaeger, KE
      Enantioselective enzymes for organic synthesis created by directed evolution

      CHEMISTRY-A EUROPEAN JOURNAL
    52. Carlon, RP; Jourdain, N; Reymond, JL
      Fluorogenic polypropionate fragments for detecting stereoselective aldolases

      CHEMISTRY-A EUROPEAN JOURNAL
    53. Venhorst, J; Onderwater, RCA; Meerman, JHN; Vermeulen, NPE; Commandeur, JNM
      Evaluation of a novel high-throughput assay for cytochrome P450 2D6 using 7-methoxy-4-(aminomethyl)-coumarin

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    54. Reetz, MT; Kuhling, KM; Hinrichs, H; Deege, A
      Circular dichroism as a detection method in the screening of enantioselective catalysts

      CHIRALITY
    55. Angelaud, R; Matsumoto, Y; Korenaga, T; Kudo, K; Senda, M; Mikami, K
      Optical rotation per refractive index unit, or enantiomeric (e) factor, for screening enantioselective catalysts through asymmetric activation or carbohydrates

      CHIRALITY
    56. Omata, K; Ishiguro, G; Yamada, M
      High-throughput screening of heterogeneous catalyst under pressurized conditions - Optimization of Cu-Mn oxide catalyst for methanol synthesis

      SEKIYU GAKKAISHI-JOURNAL OF THE JAPAN PETROLEUM INSTITUTE
    57. Li, BR; Chang, TF; Larson, A; Ding, JQ
      Identification of mRNAs expressed in tumor-infiltrating lymphocytes by a strategy for rapid and high throughput screening

      GENE
    58. Ohlstein, EH; Ruffolo, RR; Elliott, JD
      Drug discovery in the next millennium

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    59. Liyanage, MS; Xanthopoulos, KG
      Human DNA sequence polymorphisms: New opportunities for drug discovery andcustomized patient care

      DRUG DEVELOPMENT RESEARCH
    60. Versteeg, HH; Nijhuis, E; van den Brink, GR; Evertzen, M; Pynaert, GN; van Deventer, SJH; Coffer, PJ; Peppelenbosch, MP
      A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein

      BIOCHEMICAL JOURNAL
    61. Ye, QZ; Nan, FJ; Hu, LY; Qian, Z; Qian, J
      High-throughput screening for human collagenase 1 inhibitors

      ACTA PHARMACOLOGICA SINICA
    62. Park, SY; Park, SH; Lee, IS; Kong, JY
      Establishment of a high-throughput screening system for caspase-3 inhibitors

      ARCHIVES OF PHARMACAL RESEARCH
    63. Gift, EA; Weaver, JC
      Simultaneous quantitative determination of electroporative molecular uptake and subsequent cell survival using gel microdrops and flow cytometry

      CYTOMETRY
    64. Koehler, RT; Villar, HO
      Design of screening libraries biased for pharmaceutical discovery

      JOURNAL OF COMPUTATIONAL CHEMISTRY
    65. Cotenescu, MG; La Clair, JJ
      Screening hydrolysis over two-phases

      JOURNAL OF BIOTECHNOLOGY
    66. Tomasselli, AG; Heinrikson, RL
      Targeting the HIV-protease in AIDS therapy: a current clinical perspective

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    67. Alaoui-Ismaili, MH; Gervais, C; Brunette, S; Gouin, G; Hamel, M; Rando, RF; Bedard, J
      A novel high throughput screening assay for HCVNS3 helicase activity

      ANTIVIRAL RESEARCH
    68. Lin, K; Ricciardi, RP
      A rapid plate assay for the screening of inhibitors against herpesvirus DNA polymerases and processivity factors

      JOURNAL OF VIROLOGICAL METHODS
    69. Campbell, SF
      Science, art and drug discovery: a personal perspective

      CLINICAL SCIENCE
    70. Oh, HS; Lee, YH
      A target-site-specific screening system for antifungal compounds on appressorium formation in Magnaporthe grisea

      PHYTOPATHOLOGY
    71. Valko, K; Du, CM; Bevan, CD; Reynolds, DP; Abraham, MH
      Rapid-gradient HPLC method for measuring drug interactions with immobilized artificial membrane: Comparison with other lipophilicity measures

      JOURNAL OF PHARMACEUTICAL SCIENCES
    72. Daugherty, PS; Iverson, BL; Georgiou, G
      Flow cytometric screening of cell-based libraries

      JOURNAL OF IMMUNOLOGICAL METHODS
    73. Gutierrez, JA
      Genomics: from novel genes to new therapeutics in parasitology

      INTERNATIONAL JOURNAL FOR PARASITOLOGY
    74. Blackwell, JA; Tang, L; Xiang, D
      High throughput screening of drug impurity profiles using gradients in normal phase chromatography

      CHROMATOGRAPHIA
    75. Hinderling, C; Adlhart, C; Chen, P
      Thales Technologies AG - Mechanism-based high-throughput screening of catalysts

      CHIMIA
    76. Johnsson, A; Zeelenberg, I; Min, Y; Hilinski, J; Berry, C; Howell, SB; Los, G
      Identification of genes differentially expressed in association with acquired cisplatin resistance

      BRITISH JOURNAL OF CANCER
    77. Blume, AJ; Beasley, J; Goldstein, NI
      The use of peptides in diogenesis: A novel approach to drug discovery and phenomics

      BIOPOLYMERS
    78. Wenschuh, H; Volkmer-Engert, R; Schmidt, M; Schulz, M; Schneider-Mergener, J; Reineke, U
      Coherent membrane supports for parallel microsynthesis and screening of bioactive peptides

      BIOPOLYMERS
    79. George, SE; Schaeffer, MT; Cully, D; Beer, MS; McAllister, G
      A high-throughput glow-type aequorin assay for measuring receptor-mediatedchanges in intracellular calcium levels

      ANALYTICAL BIOCHEMISTRY
    80. Kuzmic, P; Elrod, KC; Cregar, LM; Sideris, S; Rai, R; Janc, JW
      High-throughput screening of enzyme inhibitors: Simultaneous determinationof tight-binding inhibition constants and enzyme concentration

      ANALYTICAL BIOCHEMISTRY
    81. Macarron, R; Mensah, L; Cid, C; Carranza, C; Benson, N; Pope, AJ; Diez, E
      A homogeneous method to measure aminoacyl-tRNA synthetase aminoacylation activity using scintillation proximity assay technology

      ANALYTICAL BIOCHEMISTRY
    82. Kuzmic, P; Sideris, S; Cregar, LM; Elrod, KC; Rice, KD; Janc, JW
      High-throughput screening of enzyme inhibitors: Automatic determination oflight-binding inhibition constants

      ANALYTICAL BIOCHEMISTRY
    83. Datti, A; Donovan, RS; Korczak, B; Dennis, JW
      A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors

      ANALYTICAL BIOCHEMISTRY
    84. Senkan, SM; Ozturk, S
      Discovery and optimization of heterogeneous catalysts by using combinatorial chemistry

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    85. Senkan, S; Krantz, K; Ozturk, S; Zengin, V; Onal, I
      High-throughput testing of heterogeneous catalyst libraries using array microreactors and mass spectrometry

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    86. Hoffmann, C; Wolf, A; Schuth, F
      Parallel synthesis and testing of catalysts under nearly conventional testing conditions

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    87. Jandeleit, B; Schaefer, DJ; Powers, TS; Turner, HW; Weinberg, WH
      Combinatorial materials science and catalysis

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    88. Reetz, MT; Becker, MH; Klein, HW; Stockigt, D
      A method for high-throughput screening of enantioselective catalysts

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    89. Henke, E; Bornscheuer, UT
      Directed evolution of an esterase from Psueudomonas fluorescens. Random mutagenesis by error-prone PCR or a mutator strain and identification of mutants showing enhanced enantioselectivity by a resorufin-based fluorescence assay

      BIOLOGICAL CHEMISTRY
    90. Strege, MA
      High-performance liquid chromatographic electrospray ionization mass spectrometric analyses for the integration of natural products with modern high-throughput screening

      JOURNAL OF CHROMATOGRAPHY B
    91. De Angelis, DA
      Why FRET over genomics?

      PHYSIOLOGICAL GENOMICS
    92. Stockwell, BR; Haggarty, SJ; Schreiber, SL
      High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications

      CHEMISTRY & BIOLOGY
    93. Mattheakis, LC; Olivan, SE; Dias, JM; Northrop, JP
      Expression of Cre recombinase as a reporter of signal transduction in mammalian cells

      CHEMISTRY & BIOLOGY
    94. Joo, H; Arisawa, A; Lin, ZL; Arnold, FH
      A high-throughput digital imaging screen for the discovery and directed evolution of oxygenases

      CHEMISTRY & BIOLOGY
    95. Ziegelbauer, K; Grusdat, G; Schade, A; Paffhausen, W
      High throughput assay to detect compounds that enhance the proton permeability of Candida albicans membranes

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    96. Knegtel, RMA; Wagener, M
      Efficacy and selectivity in flexible database docking

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    97. Jayaraman, S; Teitler, L; Skalski, B; Verkman, AS
      Long-wavelength iodide-sensitive fluorescent indicators for measurement offunctional CFTR expression in cells

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    98. Reymond, JL
      Catalytic antibodies for organic synthesis

      BIOCATALYSIS - FROM DISCOVERY TO APPLICATION
    99. Donovan, RS; Datti, A; Baek, MG; Wu, QQ; Sas, IJ; Korczak, B; Berger, EG; Roy, R; Dennis, JW
      A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research

      GLYCOCONJUGATE JOURNAL
    100. Quinn, RJ
      High-throughput screening in natural product drug discovery in Australia utilising Australia's biodiversity

      DRUG DEVELOPMENT RESEARCH


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/08/20 alle ore 10:51:47