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1. Starke, D; Lischka, K; Pagels, P; Uhlmann, E; Kramer, W; Wess, G; Petzinger, E
   Bile acid-oligodeoxynucleotide conjugates: Synthesis and liver excretion in rats
   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
   
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2. Akita, H; Suzuki, H; Sugiyama, Y
   Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver
   PHARMACEUTICAL RESEARCH
   
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3. Eppens, EF; van Mil, SWC; de Vree, JM; Mok, KS; Juijn, JA; Elferink, RPJO; Berger, R; Houwen, RHJ; Klomp, LWJ
   FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte
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4. Huang, LY; Vore, M
   Multidrug resistance P-glycoprotein 2 is essential for the biliary excretion of indocyanine green
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5. Annaert, PP; Turncliff, RZ; Booth, CL; Thakker, DR; Brouwer, KLR
   P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes
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6. Chladek, J; Martinkova, J; Sispera, L; Chladkova, J; Cermanova, J
   No effect of phenobarbital pretreatment of rats on methotrexate pharmacokinetics in the isolated liver perfused in a single-pass way
   PHARMACOLOGY
   
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7. Funk, C; Ponelle, C; Scheuermann, G; Pantze, M
   Cholestatic potential of troglitazone as a possible factor contributing totroglitazone-induced hepatotoxicity: In vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat
   MOLECULAR PHARMACOLOGY
   
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8. Jansen, PLM
   Foreword: From classic bile physiology to cloned transporters
   SEMINARS IN LIVER DISEASE
   
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9. Dombrowski, F; Kubitz, R; Chittattu, A; Wettstein, M; Saha, N; Haussinger, D
   Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide
   BIOCHEMICAL JOURNAL
   
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10. Sabordo, L; Sallustio, BC; Evans, AM; Nation, RL
    Hepatic disposition of the acyl glucuronide 1-O-gemfibrozil-beta-D-glucuronide: Effects of clofibric acid, acetaminophen, and acetaminophen glucuronide
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    
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11. Kala, SV; Neely, MW; Kala, G; Prater, CI; Atwood, DW; Rice, JS; Lieberman, MW
    The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic
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12. Gregus, Z; Gyurasics, A
    Role of glutathione in the biliary excretion of the arsenical drugs trimelarsan and melarsoprol
    BIOCHEMICAL PHARMACOLOGY
    
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13. Nakamura, J; Yoshida, Y; Mera, K; Mukai, T; Nishida, K; Sasaki, H
    Continuous microinstillation of phenol red on liver surface for liver site-selective delivery
    BIOLOGICAL & PHARMACEUTICAL BULLETIN
    
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14. Hayes, JH; Soroka, CJ; Rios-Velez, L; Boyer, JL
    Hepatic sequestration and modulation of the canalicular transport of the organic cation, daunorubicin, in the rat
    HEPATOLOGY
    
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15. Paulusma, CC; van Geer, MA; Evers, R; Heijn, M; Ottenhoff, R; Borst, P; Elferink, RPJO
    Canalicular multispecific organic onion transporter multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
    BIOCHEMICAL JOURNAL
    
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16. Lund, M; Kang, L; Tygstrup, N; Wolkoff, AW; Ott, P
    Effects of LPS on transport of indocyanine green and alanine uptake in perfused rat liver
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    
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17. Sasabe, H; Kato, Y; Terasaki, T; Tsuji, A; Sugiyama, Y
    Differences in the hepatobiliary transport of two quinolone antibiotics, grepafloxacin and lomefloxacin, in the rat
    BIOPHARMACEUTICS & DRUG DISPOSITION
    
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18. Frijters, CMG; Tuijn, CJ; Ottenhoff, R; Zegers, BN; Groen, AK; Elferink, RPJO
    The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids
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19. GREGUS Z; GYURASICS A; KOSZORUS L
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    Environmental toxicology and pharmacology
    
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20. HEDMAN A; MEIJER DKF
    THE STEREOISOMERS QUININE AND QUINIDINE EXHIBIT A MARKED STEREOSELECTIVITY IN THE INHIBITION OF HEPATOBILIARY TRANSPORT OF CARDIAC-GLYCOSIDES
    Journal of hepatology
    
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21. ROELOFSEN H; MULLER M; JANSEN PLM
    REGULATION OF ORGANIC ANION TRANSPORT IN THE LIVER
    The Yale journal of biology & medicine
    
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22. SANCHEZCAMPOS S; LOPEZACEBO R; GONZALEZ P; CULEBRAS JM; TUNON MJ; GONZALEZGALLEGO J
    CHOLESTASIS AND ALTERATIONS OF GLUTATHIONE METABOLISM INDUCED BY TACROLIMUS (FK506) IN THE RAT
    Transplantation
    
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23. HIROHASHI T; SUZUKI H; ITO K; OGAWA K; KUME K; SHIMIZU T; SUGIYAMA Y
    HEPATIC EXPRESSION OF MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN-LIKE PROTEINS MAINTAINED IN EISAI HYPERBILIRUBINEMIC RATS
    Molecular pharmacology
    
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24. SASABE H; TSUJI A; SUGIYAMA Y
    CARRIER-MEDIATED MECHANISM FOR THE BILIARY-EXCRETION OF THE QUINOLONEANTIBIOTIC GREPAFLOXACIN AND ITS GLUCURONIDE IN RATS
    The Journal of pharmacology and experimental therapeutics
    
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25. GENG WP; SCHWAB AJ; HORI T; GORESKY CA; PANG KS
    HEPATIC-UPTAKE OF BROMOSULFOPHTHALEIN-GLUTATHIONE IN PERFUSED EISAI HYPERBILIRUBINEMIC MUTANT RAT-LIVER - A MULTIPLE-INDICATOR DILUTION STUDY
    The Journal of pharmacology and experimental therapeutics
    
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26. ROELOFSEN H; SOROKA CJ; KEPPLER D; BOYER JL
    CYCLIC-AMP STIMULATES SORTING OF THE CANALICULAR ORGANIC ANION TRANSPORTER (MRP2 CMOAT) TO THE APICAL DOMAIN IN HEPATOCYTE COUPLETS/
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27. SMIT JW; DUIN E; STEEN H; OOSTING R; ROGGEVELD J; MEIJER DKF
    INTERACTIONS BETWEEN P-GLYCOPROTEIN SUBSTRATES AND OTHER CATIONIC DRUGS AT THE HEPATIC EXCRETORY LEVEL
    British Journal of Pharmacology
    
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28. GYURASICS A; PERJESI P; GREGUS Z
    ROLE OF GLUTATHIONE AND METHYLATION IN THE BILIARY-EXCRETION OF SELENIUM - THE PARADOXICAL EFFECT OF SULFOBROMOPHTHALEIN
    Biochemical pharmacology
    
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29. PAULUSMA CC; ELFERINK RPJO
    THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER AND CONJUGATED HYPERBILIRUBINEMIA IN RAT AND MAN
    Journal of molecular medicine
    
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30. DIJKSTRA M; KUIPERS F; VANDENBERG GJ; HAVINGA R; VONK RJ
    DIFFERENCES IN HEPATIC PROCESSING OF DIETARY AND INTRAVENOUSLY ADMINISTERED COPPER IN RATS
    Hepatology
    
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31. ITO K; SUZUKI H; HIROHASHI T; KUME K; SHIMIZU T; SUGIYAMA Y
    MOLECULAR-CLONING OF CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER DEFECTIVE IN EHBR
    American journal of physiology: Gastrointestinal and liver physiology
    
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32. ISHIKAWA T; LI ZS; LU YP; REA PA
    THE GS-X PUMP IN PLANT, YEAST, AND ANIMAL-CELLS - STRUCTURE, FUNCTION, AND GENE-EXPRESSION
    Bioscience reports
    
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33. YAMAZAKI M; AKIYAMA S; NIINUMA K; NISHIGAKI R; SUGIYAMA Y
    BILIARY-EXCRETION OF PRAVASTATIN IN RATS - CONTRIBUTION OF THE EXCRETION PATHWAY MEDIATED BY CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER (CMOAT)
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34. KITAURA K; TAKIKAWA H; YAMANAKA M
    EFFECTS OF ORGANIC-ANIONS AND BILE-ACID CONJUGATES ON BILIARY-EXCRETION OF LTC4 IN THE RAT
    Prostaglandins
    
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35. GAN YJ; CHODOSH J; MORGAN A; SIXBEY JW
    EPITHELIAL-CELL POLARIZATION IS A DETERMINANT IN THE INFECTIOUS OUTCOME OF IMMUNOGLOBULIN A-MEDIATED ENTRY BY EPSTEIN-BARR-VIRUS
    Journal of virology
    
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36. NIINUMA K; TAKENAKA O; HORIE T; KOBAYASHI K; KATO Y; SUZUKI H; SUGIYAMA Y
    KINETIC-ANALYSIS OF THE PRIMARY ACTIVE-TRANSPORT OF CONJUGATED METABOLITES ACROSS THE BILE CANALICULAR MEMBRANE - COMPARATIVE-STUDY OF S-(2,4-DINITROPHENYL)-GLUTATHIONE AND HYL-2-METHYLAMINO-4-(3-PYRIDYLMETHYL)BENZOTHIAZOLE GLUCURONIDE
    The Journal of pharmacology and experimental therapeutics
    
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37. CHU XY; KATO Y; NIINUMA K; SUDO K; HAKUSUI H; SUGIYAMA Y
    MULTISPECIFIC ORGANIC ANION TRANSPORTER IS RESPONSIBLE FOR THE BILIARY-EXCRETION OF THE CAMPTOTHECIN DERIVATIVE IRINOTECAN AND ITS METABOLITES IN RATS
    The Journal of pharmacology and experimental therapeutics
    
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38. ISHIZUKA H; KONNO K; NAGANUMA H; SASAHARA K; KAWAHARA Y; NIINUMA K; SUZUKI H; SUGIYAMA Y
    TEMOCAPRILAT, A NOVEL ANGIOTENSIN-CONVERTING ENZYME-INHIBITOR, IS EXCRETED IN BILE VIA AN ATP-DEPENDENT ACTIVE TRANSPORTER (CMOAT) THAT IS DEFICIENT IN EISAI HYPERBILIRUBINEMIC MUTANT RATS (EHBR)
    The Journal of pharmacology and experimental therapeutics
    
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39. ROELOFSEN H; VOS TA; SCHIPPERS IJ; KUIPERS F; KONING H; MOSHAGE H; JANSEN PLM; MULLER M
    INCREASED LEVELS OF THE MULTIDRUG-RESISTANCE PROTEIN IN LATERAL MEMBRANES OF PROLIFERATING HEPATOCYTE-DERIVED CELLS
    Gastroenterology
    
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40. MASUDA M; IIZUKA Y; YAMAZAKI M; NISHIGAKI R; KATO Y; NIINUMA K; SUZUKI H; SUGIYAMA Y
    METHOTREXATE IS EXCRETED INTO THE BILE BY CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN RATS
    Cancer research
    
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41. CHU XY; KATO Y; SUGIYAMA Y
    MULTIPLICITY OF BILIARY-EXCRETION MECHANISMS FOR IRINOTECAN, CPT-11, AND ITS METABOLITES IN RATS
    Cancer research
    
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42. TAKIKAWA H; SANO N; TADOKORO K; YAMANAKA M
    BILIARY-EXCRETION OF ESTRONE METABOLITES IN THE RAT
    HEPATOLOGY RESEARCH
    
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43. TAKIKAWA H; SANO N; FUKUMURA S; UEGAKI S; YAMANAKA M
    IMPAIRED BILIARY-EXCRETION OF ORGANIC-ANIONS AND CATIONS IN BILE DUCT-LIGATED RAT
    HEPATOLOGY RESEARCH
    
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44. CHAN OH; STEWART BH
    PHYSICOCHEMICAL AND DRUG-DELIVERY CONSIDERATIONS FOR ORAL-DRUG BIOAVAILABILITY
    Drug discovery today
    
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45. YAMAZAKI M; SUZUKI H; SUGIYAMA Y
    RECENT ADVANCES IN CARRIER-MEDIATED HEPATIC-UPTAKE AND BILIARY-EXCRETION OF XENOBIOTICS
    Pharmaceutical research
    
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46. SHIMAMURA H; SUZUKI H; TAGAYA O; HORIE T; SUGIYAMA Y
    BILIARY-EXCRETION OF GLYCYRRHIZIN IN RATS - KINETIC BASIS FOR MULTIPLICITY IN BILE CANALICULAR TRANSPORT OF ORGANIC-ANIONS
    Pharmaceutical research
    
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47. TAKIKAWA H; YAMAZAKI R; SANO N; YAMANAKA M
    BILIARY-EXCRETION OF ESTRADIOL-17-BETA-GLUCURONIDE IN THE RAT
    Hepatology
    
    H. Takikawa et al., "BILIARY-EXCRETION OF ESTRADIOL-17-BETA-GLUCURONIDE IN THE RAT", Hepatology, 23(3), 1996, pp. 607-613
48. GROOTHUIS GMM; MEIJER DKF
    DRUG TRAFFIC IN THE HEPATOBILIARY SYSTEM
    Journal of hepatology
    
    G.M.M. Groothuis e D.K.F. Meijer, "DRUG TRAFFIC IN THE HEPATOBILIARY SYSTEM", Journal of hepatology, 24, 1996, pp. 3-28
49. TAKIKAWA H; SANO N; YAMANAKA M
    EFFECTS OF URSODEOXYCHOLATE AND ITS CONJUGATES ON BILIARY GLUTATHIONEEXCRETION IN RATS
    Digestive diseases and sciences
    
    H. Takikawa et al., "EFFECTS OF URSODEOXYCHOLATE AND ITS CONJUGATES ON BILIARY GLUTATHIONEEXCRETION IN RATS", Digestive diseases and sciences, 41(10), 1996, pp. 1953-1958
50. YAMAZAKI M; KOBAYASHI K; SUGIYAMA Y
    PRIMARY ACTIVE-TRANSPORT OF PRAVASTATIN ACROSS THE LIVER CANALICULAR MEMBRANE IN NORMAL AND MUTANT EISAI HYPERBILIRUBINEMIC RATS
    Biopharmaceutics & drug disposition
    
    M. Yamazaki et al., "PRIMARY ACTIVE-TRANSPORT OF PRAVASTATIN ACROSS THE LIVER CANALICULAR MEMBRANE IN NORMAL AND MUTANT EISAI HYPERBILIRUBINEMIC RATS", Biopharmaceutics & drug disposition, 17(8), 1996, pp. 645-659
51. YAMAZAKI M; KOBAYASHI K; SUGIYAMA Y
    PRIMARY ACTIVE-TRANSPORT OF PRAVASTATIN ACROSS THE LIVER CANALICULAR MEMBRANE IN NORMAL AND MUTANT EISAI HYPERBILIRUBINEMIC RATS
    Biopharmaceutics & drug disposition
    
    M. Yamazaki et al., "PRIMARY ACTIVE-TRANSPORT OF PRAVASTATIN ACROSS THE LIVER CANALICULAR MEMBRANE IN NORMAL AND MUTANT EISAI HYPERBILIRUBINEMIC RATS", Biopharmaceutics & drug disposition, 17(7), 1996, pp. 607-621
52. DUMONT M; DHONT C; FELDMANN G; ROGIER E; MOREAU A; JANSEN PLM; ERLINGER S
    EFFECT OF DIETHYLMALEATE ON BILE SECRETION AND ULTRASTRUCTURAL APPEARANCE OF HEPATOCYTES IN NORMAL RATS AND MUTANT RATS WITH DEFECTIVE ORGANIC ANION SECRETION
    Liver
    
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53. TAKIKAWA H; FUJIYOSHI M; SANO N; YAMANAKA M
    EFFECTS OF ORGANIC-ANIONS ON BILIARY GLUTATHIONE EXCRETION IN RATS
    Pharmacology
    
    H. Takikawa et al., "EFFECTS OF ORGANIC-ANIONS ON BILIARY GLUTATHIONE EXCRETION IN RATS", Pharmacology, 53(2), 1996, pp. 114-122
54. DIJKSTRA M; HAVINGA R; VONK RJ; KUIPERS F
    BILE SECRETION OF CADMIUM, SILVER, ZINC AND COPPER IN THE RAT - INVOLVEMENT OF VARIOUS TRANSPORT-SYSTEMS
    Life sciences
    
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55. YAMADA T; NIINUMA K; LEMAIRE M; TERASAKI T; SUGIYAMA Y
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56. SCHWAB D; THOM H; HEINZE J; KURZ G
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57. STEINMETZ I; SCHIFFMANN P; BRENNEKE B
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58. TAKENAKA O; HORIE T; KOBAYASHI K; SUZUKI H; SUGIYAMA Y
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59. ROELOFSEN H; BAKKER CTM; SCHOEMAKER B; HEIJN M; JANSEN PLM; ELFERINK RPJO
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60. ROELOFSEN H; SCHOEMAKER B; BAKKER C; OTTENHOFF R; JANSEN PLM; ELFERINK RPJO
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61. WATANABE T; SUZUKI H; SAWADA Y; NAITO M; TSURUO T; INABA M; HANANO M; SUGIYAMA Y
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62. YASUI H; YAMAOKA K; NAKAGAWA T
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63. TAKENAKA O; HORIE T; SUZUKI H; SUGIYAMA Y
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64. DIETRICH A; DIEMINGER W; MACNELLY S; GEROK W; KURZ G
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65. DIETRICH A; DIEMINGER W; FUCHTE K; STOLL GH; SCHLITZ E; GEROK W; KURZ G
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66. BERK PD; NOYER C
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67. HOSHINO M; HAYAKAWA T; HIRANO A; KAMIYA Y; OHIWA T; TANAKA A; KUMAI T; INAGAKI T; MIYAJI M; TAKEUCHI T
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68. STEEN H; MEREMA M; MEIJER DKF
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69. ROMA MG; PENALVA GL; AGUERO RM; GARAY EAR
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70. ELFERINK RPJO; JANSEN PLM
    THE ROLE OF THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN THE DISPOSAL OF ENDOBIOTICS AND XENOBIOTICS
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71. ELFERINK RPJO; JANSEN PLM
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72. HYLAND L; HOU S; COLECLOUGH C; TAKIMOTO T; DOHERTY PC
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73. SHIMAMURA H; SUZUKI H; HANANO M; SUZUKI A; TAGAYA O; HORIE T; SUGIYAMA Y
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74. SATHIRAKUL K; SUZUKI H; YAMADA T; HANANO M; SUGIYAMA Y
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75. ROELOFSEN H; VANDERVEERE CN; OTTENHOFF R; SCHOEMAKER B; JANSEN PLM; ELFERINK RPJO
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    Gastroenterology
    
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76. BENZICK AE; REDDY SL; GUPTA S; ROGERS LK; SMITH CV
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77. KAUR B; AHUJA SP
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78. BARTOSZ G; SIES H; AKERBOOM TPM
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79. SMIT JJM; SCHINKEL AH; ELFERINK RPJO; GROEN AK; WAGENAAR E; VANDEEMTER L; MOL CAAM; OTTENHOFF R; VANDERLUGT NMT; VANROON MA; VANDERVALK MA; OFFERHAUS GJA; BERNS AJM; BORST P
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80. SCHRAMM U; FRICKER G; BUSCHER HP; GEROK W; KURZ G
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81. FERNANDEZCHECA JC; OOKHTENS M; KAPLOWITZ N
    SELECTIVE INDUCTION BY PHENOBARBITAL OF THE ELECTROGENIC TRANSPORT OFGLUTATHIONE AND ORGANIC-ANIONS IN RAT-LIVER CANALICULAR MEMBRANE-VESICLES
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