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La ricerca find articoli where soggetti phrase all words 'hammerhead ribozyme' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 528 riferimenti
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    1. Thomas, M; Clivio, P; Guillaume, D; Fourrey, JL
      Synthesis and photochemical behaviour of a T-T dimer containing an amide linkage

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    2. Kaukinen, U; Bielecki, L; Mikkola, S; Adamiak, RW; Lonnberg, H
      The cleavage of phosphodiester bonds within small RNA bulges in the presence and absence of metal ion catalysts

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    3. Lilley, DMJ
      Origins of RNA catalysis in the hairpin ribozyme

      CHEMBIOCHEM
    4. Sekine, M; Kurasawa, O; Shohda, K; Seio, K; Wada, T
      Essential factors for stabilization of the predominant C3 '-endo conformation in dinucleoside phosphotriester derivatives with cyclonucleotide bridgestructures at the downstream 3 '-position

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    5. Feng, Y; Kong, YY; Wang, Y; Qi, GR
      Inhibition of hepatitis B virus by hammerhead ribozyme targeted to the poly(A) signal sequence in cultured cells

      BIOLOGICAL CHEMISTRY
    6. Holbrook, SR; Holbrook, EL; Walukiewicz, HE
      Crystallization of RNA

      CELLULAR AND MOLECULAR LIFE SCIENCES
    7. Hughes, MD; Hussain, M; Nawaz, Q; Sayyed, P; Akhtar, S
      The cellular delivery of antisense oligonucleotides and ribozymes

      DRUG DISCOVERY TODAY
    8. Curtis, EA; Bartel, DP
      The hammerhead cleavage reaction in monovalent cations

      RNA-A PUBLICATION OF THE RNA SOCIETY
    9. Pan, WH; Devlin, HF; Kelley, C; Isom, HC; Clawson, GA
      A selection system for identifying accessible sites in target RNAs

      RNA-A PUBLICATION OF THE RNA SOCIETY
    10. Tereshko, V; Wallace, ST; Usman, N; Wincott, FE; Egli, M
      X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid

      RNA-A PUBLICATION OF THE RNA SOCIETY
    11. Sherlin, LD; Bullock, TL; Nissan, TA; Perona, JJ; Lariviere, FJ; Uhlenbeck, OC; Scaringe, SA
      Chemical and enzymatic synthesis of tRNAs for high-throughput crystallization

      RNA-A PUBLICATION OF THE RNA SOCIETY
    12. Nonekowski, ST; Garcia, GA
      tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: The role of U33 in U-G-U sequence recognition

      RNA-A PUBLICATION OF THE RNA SOCIETY
    13. Williams, DJ; Boots, JL; Hall, KB
      Thermodynamics of 2 '-ribose substitutions in UUCG tetraloops

      RNA-A PUBLICATION OF THE RNA SOCIETY
    14. Das, M; Harvey, I; Chu, LL; Sinha, M; Pelletier, J
      Full-length cDNAs: more than just reaching the ends

      PHYSIOLOGICAL GENOMICS
    15. Jenne, A; Hartig, JS; Piganeau, N; Tauer, A; Samarsky, DA; Green, MR; Davies, J; Famulok, M
      Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology

      NATURE BIOTECHNOLOGY
    16. Mikkelsen, NE; Johansson, K; Virtanen, A; Kirsebom, LA
      Aminoglycoside binding displaces a divalent metal ion in a tRNA-neomycin Bcomplex

      NATURE STRUCTURAL BIOLOGY
    17. Walter, NG
      Structural dynamics of catalytic RNA highlighted by fluorescence resonanceenergy transfer

      METHODS
    18. Klostermeier, D; Millar, DP
      RNA conformation and folding studied with fluorescence resonance energy transfer

      METHODS
    19. Switzer, C; Chaput, JC
      Probing structure and function with alternative nucleic acids bearing 2 ',5 '-linked, zwitterionic, and isocytosine center dot isoguanine components

      METHODS
    20. Yang, JZ; Ratovitski, T; Brady, JP; Solomon, MB; Wells, KD; Wall, RJ
      Expression of myostatin pro domain results in muscular transgenic mice

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    21. Juneau, K; Podell, E; Harrington, DJ; Cech, TR
      Structural basis of the enhanced stability of a mutant ribozyme domain anda detailed view of RNA-solvent interactions

      STRUCTURE
    22. Araki, M; Hashima, M; Okuno, Y; Sugiura, Y
      Coupling between substrate binding and allosteric regulation in ribozyme catalysis

      BIOORGANIC & MEDICINAL CHEMISTRY
    23. Frauendorf, C; Jaschke, A
      Detection of small organic analytes by fluorescing molecular switches

      BIOORGANIC & MEDICINAL CHEMISTRY
    24. Ryu, DH; Rando, RR
      Aminoglycoside binding to human and bacterial A-site rRNA decoding region constructs

      BIOORGANIC & MEDICINAL CHEMISTRY
    25. Tok, JBH; Dunn, LJ; Jean, RCD
      Binding of dimeric aminoglycosides to the HIV-1 Rev responsive element (RRE) RNA construct

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    26. Butcher, SE
      Structure and function of the small ribozymes

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    27. Zhang, YJ; Wang, XP; Deng, JH; Salinas, RA; Oishi, N; Gao, SJ
      Suppression of oncogenic viral interferon regulatory factor (vIRF) of Kaposi's sarcoma-associated herpesvirus by ribozyme-mediated cleavage

      CANCER GENE THERAPY
    28. Iida, T; Kijima, H; Urata, Y; Goto, S; Ihara, Y; Oka, M; Kohno, S; Scanlon, KJ; Kondo, T
      Hammerhead ribozyme against gamma-glutamylcysteine synthetase sensitizes human colonic cancer cells to cisplatin by down-regulating both the glutathione synthesis and the expression of multidrug resistance proteins

      CANCER GENE THERAPY
    29. Tanaka, T; Inui, O; Dohi, N; Okada, N; Okada, H; Kikuchi, Y
      Is your ribozyme design really correct?: A proposal of simple single turnover competition assay to evaluate ribozymes

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    30. Perbandt, M; Vallazza, M; Lippmann, C; Betzel, C; Erdmann, VA
      Structure of an RNA duplex with an unusual G center dot C pair in wobble-like conformation at 1.6 angstrom resolution

      ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    31. Ennifar, E; Walter, P; Dumas, P
      An efficient method for solving RNA structures: MAD phasing by replacing magnesium with zinc

      ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    32. Lee, NS; Sun, BH; Williamson, R; Gunkel, N; Salvaterra, PM; Rossi, JJ
      Functional colocalization of ribozymes and target mRNAs in Drosophila oocytes

      FASEB JOURNAL
    33. Rooney, JW; Calame, KL
      TIF1 beta functions as a coactivator for C/EBP beta and is required for induced differentiation in the myelomonocytic cell line U937

      GENES & DEVELOPMENT
    34. Kumar, VB; Vyas, K; Franko, M; Choudhary, V; Buddhiraju, C; Alvarez, J; Morley, JE
      Molecular cloning, expression, and regulation of hippocampal amyloid precursor protein of senescence accelerated mouse (SAMP8)

      BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
    35. Flores, R
      A naked plant-specific RNA ten-fold smaller than the smallest known viral RNA: the viroid

      COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES
    36. Wright, L; Kearney, P
      Current status of ribozymes as gene therapy agents for cancer

      CANCER INVESTIGATION
    37. Miyagishi, M; Kuwabara, T; Taira, K
      Transport of intracellularly active ribozymes to the cytoplasm

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    38. Belmont, P; Constant, JF; Demeunynck, M
      Nucleic acid conformation diversity: from structure to function and regulation

      CHEMICAL SOCIETY REVIEWS
    39. Takagi, Y; Warashina, M; Stec, WJ; Yoshinari, K; Taira, K
      Recent advances in the elucidation of the mechanisms of action of ribozymes

      NUCLEIC ACIDS RESEARCH
    40. Kruger, M; Beger, C; Welch, PJ; Barber, JR; Wong-Staal, F
      C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification

      NUCLEIC ACIDS RESEARCH
    41. Rist, MJ; Marino, JP
      Association of an RNA kissing complex analyzed using 2-aminopurine fluorescence

      NUCLEIC ACIDS RESEARCH
    42. Hubinger, G; Schmid, M; Linortner, S; Manegold, A; Bergmann, L; Maurer, U
      Ribozyme-mediated cleavage of wt1 transcripts suppresses growth of leukemia cells

      EXPERIMENTAL HEMATOLOGY
    43. Muller, UF; Lambert, L; Goringer, HU
      Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21

      EMBO JOURNAL
    44. Lafontaine, DA; Norman, DG; Lilley, DMJ
      Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction

      EMBO JOURNAL
    45. Shih, IH; Been, MD
      Energetic contribution of non-essential 5 ' sequence to catalysis in a hepatitis delta virus ribozyme

      EMBO JOURNAL
    46. Wyszko, E; Barciszewska, MZ; Bald, R; Erdmann, VA; Barciszewski, J
      The specific hydrolysis of HIV-1 TAR RNA element with the anti-TAR hammerhead ribozyme: structural and functional implications

      INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
    47. David, L; Lambert, D; Gendron, P; Major, F
      Leadzyme

      RIBONUCLEASES, PT A
    48. Michienzi, A; Rossi, JJ
      Intracellular applications of ribozymes

      RIBONUCLEASES, PT A
    49. Gonzalez, RL; Tinoco, I
      Identification and characterization of metal ion binding sites in RNA

      NUCLEAR MAGNETIC RESONANCE OF BIOLOGICA MACROMOLECULES, PT A
    50. Gallo, M; Monteagudo, E; Cicero, DO; Torres, HN; Iribarren, AM
      2 '-C-methyluridine phosphoramidite: a new building block for the preparation of RNA analogues carrying the 2 '-hydroxyl group

      TETRAHEDRON
    51. Warashina, M; Kuwabara, T; Kato, Y; Sano, M; Taira, K
      RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    52. Orlando, C; Gelmini, S; Selli, C; Pazzagli, M
      Telomerase in urological malignancy

      JOURNAL OF UROLOGY
    53. Sood, VD; Collins, RA
      Functional equivalence of the uridine turn and the hairpin as building blocks of tertiary structure in the Neurospora VS ribozyme

      JOURNAL OF MOLECULAR BIOLOGY
    54. Lafontaine, DA; Wilson, TJ; Norman, DG; Lilley, DMJ
      The A730 loop is an important component of the active site of the VS ribozyme

      JOURNAL OF MOLECULAR BIOLOGY
    55. Scott, WG
      Ribozyme catalysis via orbital steering

      JOURNAL OF MOLECULAR BIOLOGY
    56. Wang, DY; Sen, D
      A novel mode of regulation of an RNA-cleaving DNAzyme by effectors that bind to both enzyme and substrate

      JOURNAL OF MOLECULAR BIOLOGY
    57. Flinders, J; Dieckmann, T
      A pH controlled conformational switch in the cleavage site of the VS ribozyme substrate RNA

      JOURNAL OF MOLECULAR BIOLOGY
    58. Pinard, R; Lambert, D; Heckman, JE; Esteban, JA; Gundlach, CW; Hampel, KJ; Glick, GD; Walter, NG; Major, F; Burke, JM
      The hairpin ribozyme substrate binding-domain: A highly constrained D-shaped conformation

      JOURNAL OF MOLECULAR BIOLOGY
    59. Zuleeg, T; Hartmann, RK; Kreutzer, R; Limmer, S
      NMR spectroscopic evidence for Mn2+(Mg2+) binding to a precursor-tRNA microhelix near the potential RNase P cleavage site

      JOURNAL OF MOLECULAR BIOLOGY
    60. Kato, Y; Kuwabara, T; Warashina, M; Toda, H; Taira, K
      Relationships between the activities in vitro and in vivo of various kindsof ribozyme and their intracellular localization in mammalian cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    61. Grobe, O; Arlt, A; Ungefroren, H; Krupp, G; Folsch, UR; Schmidt, WE; Schafer, H
      Functional disruption of IEX-1 expression by concatemeric hammerhead ribozymes alters growth properties of 293 cells

      FEBS LETTERS
    62. Hertweck, M; Mueller, MW
      Mapping divalent metal ion binding sites in a group II intron by Mn2+- andZn2+-induced site-specific RNA cleavage

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    63. Chio, CC; Wang, YS; Chen, YL; Lin, SJ; Yang, BC
      Down-regulation of Fas-L in glioma cells by ribozyme reduces cell apoptosis, tumour-infiltrating cells, and liver damage but accelerates tumour formation in nude mice

      BRITISH JOURNAL OF CANCER
    64. Wilson, TJ; Zhao, ZY; Maxwell, K; Kontogiannis, L; Lilley, DMJ
      Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme

      BIOCHEMISTRY
    65. Flynn-Charlebois, A; Lee, N; Suga, H
      A single metal ion plays structural and chemical roles in an aminoacyl-transferase ribozyme

      BIOCHEMISTRY
    66. Lee, N; Suga, H
      Essential roles of innersphere metal ions for the formation of the glutamine binding site in a bifunctional ribozyme

      BIOCHEMISTRY
    67. Greenbaum, NL; Mundoma, C; Peterman, DR
      Probing of metal-binding domains of RNA hairpin loops by laser-induced lanthanide(III) luminescence

      BIOCHEMISTRY
    68. Qin, H; Sosnick, TR; Pan, T
      Modular construction of a tertiary RNA structure: The specificity domain of the Bacillus subtilis RNase P RNA

      BIOCHEMISTRY
    69. Vaidya, A; Suga, H
      Diverse roles of metal ions in acyl-transferase ribozymes

      BIOCHEMISTRY
    70. Diamond, JM; Turner, DH; Mathews, DH
      Thermodynamics of three-way multibranch loops in RNA

      BIOCHEMISTRY
    71. Dolzhanskaya, N; Conti, J; Schwenk, V; Merz, G; Denman, RB
      Self-cleaving-ribozyme-mediated reduction of beta APP in human rhabdomyosarcoma cells

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    72. Edwards, TE; Okonogi, TM; Robinson, BH; Sigurdsson, ST
      Site-specific incorporation of nitroxide spin-labels into internal sites of the TAR RNA; structure-dependent dynamics of RNA by EPR spectroscopy

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    73. Tanabe, T; Takata, I; Kuwabara, T; Warashina, M; Kawasaki, H; Tani, K; Ohta, S; Asano, S; Taira, K
      Maxizymes, novel allosterically controllable ribozymes, can be designed tocleave various substrates

      BIOMACROMOLECULES
    74. Scherr, M; Reed, M; Huang, CF; Riggs, AD; Rossi, JJ
      Oligonucleotide scanning of native mRNAs in extracts predicts intracellular ribozyme efficiency: Ribozyme-mediated reduction of the murine DNA methyltransferase

      MOLECULAR THERAPY
    75. Burlina, F; Favre, A; Fourrey, JL; Thomas, M
      Replacement of the cleavable phosphodiester bond of a hammerhead ribozyme substrate by an amide linkage

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    76. Sucheck, SJ; Greenberg, WA; Tolbert, TJ; Wong, CH
      Design of small molecules that recognize RNA: Development of aminoglycosides as potential antitumor agents that target oncogenic RNA sequences

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    77. Yim, SH; Park, I; Ahn, JK; Kang, CW
      Translational suppression by hammerhead ribozymes and inactive variants inS-cerevisiae

      BIOMOLECULAR ENGINEERING
    78. Lilley, DMJ; Wilson, TJ
      Fluorescence resonance energy transfer as a structural tool for nucleic acids

      CURRENT OPINION IN CHEMICAL BIOLOGY
    79. Hanna, R; Doudna, JA
      Metal ions in ribozyme folding and catalysis

      CURRENT OPINION IN CHEMICAL BIOLOGY
    80. Dorai, T; Gehani, N; Katz, A
      Therapeutic potential of curcumin in human prostate cancer - I. curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells

      PROSTATE CANCER AND PROSTATIC DISEASES
    81. Shan, SO; Herschlag, D
      An unconventional origin of metal-ion rescue and inhibition in the Tetrahymena group I ribozyme reaction

      RNA-A PUBLICATION OF THE RNA SOCIETY
    82. Dale, T; Smith, R; Serra, MJ
      A test of the model to predict unusually stable RNA hairpin loop stability

      RNA-A PUBLICATION OF THE RNA SOCIETY
    83. Vitiello, D; Pecchia, DB; Burke, JM
      Intracellular ribozyme-catalyzed trans-cleavage of RNA monitored by fluorescence resonance energy transfer

      RNA-A PUBLICATION OF THE RNA SOCIETY
    84. Michiels, PJA; Schouten, CHJ; Hilbers, CW; Heus, HA
      Structure of the ribozyme substrate hairpin of Neurospora VS RNA: A close look at the cleavage site

      RNA-A PUBLICATION OF THE RNA SOCIETY
    85. Minasov, G; Matulic-Adamic, J; Wilds, CJ; Haeberli, P; Usman, N; Beigelman, L; Egli, M
      Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines

      RNA-A PUBLICATION OF THE RNA SOCIETY
    86. Andersen, AA; Collins, RA
      Rearrangement of a stable RNA secondary structure during VS ribozyme catalysis

      MOLECULAR CELL
    87. Murray, JB; Szoke, H; Szoke, A; Scott, WG
      Capture and visualization of a catalytic RNA enzyme-product complex using crystal lattice trapping and X-ray holographic reconstruction

      MOLECULAR CELL
    88. Lazowski, KW; Kaczmarek, L
      Highly sensitive detection of hybridization of oligonucleotides to specific sequences of nucleic acids by application of fluorescence resonance energy transfer

      ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT
    89. Jen, KY; Gewirtz, AM
      Suppression of gene expression by targeted disruption of messenger RNA: Available options and current strategies

      STEM CELLS
    90. Jovine, L; Hainzl, T; Oubridge, C; Scott, WG; Li, J; Sixma, TK; Wonacott, A; Skarzynski, T; Nagai, K
      Crystal structure of the Ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA

      STRUCTURE WITH FOLDING & DESIGN
    91. Westhof, E; Fritsch, V
      RNA folding: beyond Watson-Crick pairs

      STRUCTURE WITH FOLDING & DESIGN
    92. Warashina, M; Kuwabara, T; Taira, K
      Working at the cutting edge: the creation of allosteric ribozymes

      STRUCTURE
    93. Alefelder, S; Sigurdsson, ST
      Interstrand disulfide cross-linking of internal sugar residues in duplex RNA

      BIOORGANIC & MEDICINAL CHEMISTRY
    94. Han, SC; Wu, ZJ; Yang, HY; Wang, R; Yie, Y; Xie, LH; Tien, P
      Ribozyme-mediated resistance to rice dwarf virus and the transgene silencing in the progeny of transgenic rice plants

      TRANSGENIC RESEARCH
    95. Jaikaran, DCJ; MacMillan, AM
      Template-directed interference footprinting for RNA based on inosine-specific cleavage

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    96. Tok, JBH; Huffman, GR
      Enhanced binding of aminoglycoside dimers to a "dimerized" A-site 16S rRNAconstruct

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    97. Warashina, M; Takagi, Y; Stec, WJ; Taira, K
      Differences among mechanisms of ribozyme-catalyzed reactions

      CURRENT OPINION IN BIOTECHNOLOGY
    98. Wilson, WD; Li, K
      Targeting RNA with small molecules

      CURRENT MEDICINAL CHEMISTRY
    99. Mariani, L; Citti, L; Nevischi, S; Eckstein, F; Rainaldi, G
      Ribozyme and free alkylated base: a dual approach for sensitizing Mex(+) cells to the alkylating antineoplastic drug

      CANCER GENE THERAPY
    100. Cheng, J; Luo, JY; Zhang, XY; Hu, JL; Hui, HX; Wang, CJ; Stern, A
      Inhibition of cell proliferation in HCC-9204 hepatoma cells by a c-myc specific ribozyme

      CANCER GENE THERAPY


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Documento generato il 12/08/20 alle ore 06:21:41