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La ricerca find articoli where soggetti phrase all words 'green tea' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 701 riferimenti
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    1. Zvetkova, E; Wirleitner, B; Tram, NT; Schennach, H; Fuchs, D
      Aqueous extracts of Crinum latifolium (L.) and Camellia sinensis show immunomodulatory properties in human peripheral blood mononuclear cells

      INTERNATIONAL IMMUNOPHARMACOLOGY
    2. Osada, K; Takahashi, M; Hoshina, S; Nakamura, M; Nakamura, S; Sugano, M
      Tea catechins inhibit cholesterol oxidation accompanying oxidation of low density lipoprotein in vitro

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
    3. Yokoyama, S; Hirano, H; Wakimaru, N; Sarker, KP; Kuratsu, J
      Inhibitory effect of epigallocatechin-gallate on brain tumor cell lines invitro

      NEURO-ONCOLOGY
    4. Shashkin, PN; Wasner, HK; Ortmeyer, HK; Hansen, BC
      Prostaglandylinositol cyclic phosphate (cPIP): a novel second messenger ofinsulin action. Comparative analysis of two kinds of 'insulin mediators'

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    5. Wachira, F; Tanaka, J; Takeda, Y
      Genetic variation and differentiation in tea (Camellia sinensis) germplasmrevealed by RAPD and AFLP variation

      JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY
    6. Riemersma, RA; Rice-Evans, CA; Tyrrell, RM; Clifford, MN; Lean, MEJ
      Tea flavonoids and cardiovascular health

      QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS
    7. Yanishlieva, NV; Marinova, EM
      Stabilisation of edible oils with natural antioxidants

      EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
    8. Tang, SZ; Kerry, JP; Sheehan, D; Buckley, DJ
      A comparative study of tea catechins and alpha-tocopherol as antioxidants in cooked beef and chicken meat

      EUROPEAN FOOD RESEARCH AND TECHNOLOGY
    9. Gupta, S; Mukhtar, H
      Chemoprevention of skin cancer through natural agents

      SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY
    10. Ahmad, N; Mukhtar, H
      Cutaneous photochemoprotection by green tea: A brief review

      SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY
    11. Kim, J; Hwang, JS; Cho, YK; Han, YK; Jeon, YJ; Yang, KH
      Protective effects of (-)-epigallocatechin-3-gallate on UVA- and UVB-induced skin damage

      SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY
    12. Long, H; Zhu, YX; Cregor, M; Tian, FF; Coury, L; Kissinger, CB; Kissinger, PT
      Liquid chromatography with multi-channel electrochemical detection for thedetermination of epigallocatechin gallate in rat plasma utilizing an automated blood sampling device

      JOURNAL OF CHROMATOGRAPHY B
    13. Mulder, TPJ; van Platerink, CJ; Schuyl, PJW; van Amelsvoort, JMM
      Analysis of theaflavins in biological fluids using liquid chromatography-electrospray mass spectrometry

      JOURNAL OF CHROMATOGRAPHY B
    14. Weisburger, JH
      Antimutagenesis and anticarcinogenesis, from the past to the future

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    15. Mure, K; Rossman, TG
      Reduction of spontaneous mutagenesis in mismatch repair-deficient and proficient cells by dietary antioxidants

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    16. Jiang, T; Glickman, BW; de Boer, JG
      Protective effect of green tea against benzo[a]pyrene-induced mutations inthe liver of Big Blue((R)) transgenic mice

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    17. Trosko, JE; Chang, CC
      Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    18. Fujiki, H; Suganuma, M; Okabe, S; Sueoka, E; Sueoka, N; Fujimoto, N; Goto, Y; Matsuyama, S; Imai, K; Nakachi, K
      Cancer prevention with green tea and monitoring by a new biomarker, hnRNP B1

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    19. Ferguson, LR
      Role of plant polyphenols in genomic stability

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    20. Ohe, T; Marutani, K; Nakase, S
      Catechins are not major components responsible for anti-genotoxic effects of tea extracts against nitroarenes

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    21. Brown, B; Avalos, J; Lee, C; Doolittle, D
      The effect of tobacco smoke, nicotine, and cotinine on the mutagenicity of4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    22. Long, H; Zhu, YX; Huang, YH; Coury, LA; Kissinger, PT
      Identification and determination of polyphenols in tea by liquid chromatography with multichannel electrochemical detection

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    23. Ohnishi, ST; Ohnishi, T; Ogunmola, GB
      Green tea extract and aged garlic extract inhibit anion transport and sickle cell dehydration in vitro

      BLOOD CELLS MOLECULES AND DISEASES
    24. Dog, TL; Riley, D; Carter, T
      Traditional and alternative therapies for breast cancer

      ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
    25. Ahmad, N; Adhami, VM; Afaq, F; Feyes, DK; Mukhtar, H
      Resveratrol causes WAF-l/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells

      CLINICAL CANCER RESEARCH
    26. Esimone, CO; Adikwu, MU; Nwafor, SV; Okolo, CO
      Potential use of tea extract as a complementary mouthwash: Comparative evaluation of two commercial samples

      JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
    27. Yoshioka, H; Ohashi, Y; Akaboshi, M; Senba, Y; Yoshioka, H
      A novel method of measuring hydroxyl radical-scavenging activity of antioxidants using gamma-irradiation

      FREE RADICAL RESEARCH
    28. Zhong, LJ; Goldberg, MS; Gao, YT; Hanley, JA; Parent, ME; Jin, F
      A population-based case-control study of lung cancer and green tea consumption among women living in Shanghai, China

      EPIDEMIOLOGY
    29. Crouvezier, S; Powell, B; Keir, D; Yaqoob, P
      The effects of phenolic components of tea on the production of pro- and anti-inflammatory cytokines by human leukocytes in vitro

      CYTOKINE
    30. Katiyar, SK; Elmets, CA
      Green tea polyphenolic antioxidants and skin photoprotection (Review)

      INTERNATIONAL JOURNAL OF ONCOLOGY
    31. Zhu, AZ; Wang, XY; Guo, ZQ
      Study of tea polyphenol as a reversal agent for carcinoma cell lines' multidrug resistance (study of TP as a MDR reversal agent)

      NUCLEAR MEDICINE AND BIOLOGY
    32. Cavalier, JF; Burton, M; Dussart, F; Marchand, C; Rees, JF; Marchand-Brynaert, J
      Catechol derivatives of aminopyrazine and cell protection against UVB-induced mortality

      BIOORGANIC & MEDICINAL CHEMISTRY
    33. Tang, S; Kerry, JP; Sheehan, D; Buckley, DJ; Morrissey, PA
      Antioxidative effect of added tea catechins on susceptibility of cooked red meat, poultry and fish patties to lipid oxidation

      FOOD RESEARCH INTERNATIONAL
    34. Nagano, J; Kono, S; Preston, DL; Mabuchi, K
      A prospective study of green tea consumption and cancer incidence, Hiroshima and Nagasaki (Japan)

      CANCER CAUSES & CONTROL
    35. Dufresne, CJ; Farnworth, ER
      A review of latest research findings on the health promotion properties oftea

      JOURNAL OF NUTRITIONAL BIOCHEMISTRY
    36. Arts, ICW; Hollman, PCH; Feskens, EJM; de Mesquita, HBB; Kromhout, D
      Catechin intake and associated dietary and lifestyle factors in a representative sample of Dutch men and women

      EUROPEAN JOURNAL OF CLINICAL NUTRITION
    37. Hodgson, JM; Puddey, IB; Mori, TA; Burke, V; Baker, RI; Beilin, LJ
      Effects of regular ingestion of black tea on haemostasis and cell adhesionmolecules in humans

      EUROPEAN JOURNAL OF CLINICAL NUTRITION
    38. Tang, SZ; Sheehan, D; Buckley, DJ; Morrissey, PA; Kerry, JP
      Anti-oxidant activity of added tea catechins on lipid oxidation of raw minced red meat, poultry and fish muscle

      INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
    39. Gee, JM; Johnson, IT
      Polyphenolic compounds: Interactions with the gut and implications for human health

      CURRENT MEDICINAL CHEMISTRY
    40. Gao, JT; Tang, HR; Zhao, BL
      Toxicologic damage of gas phase cigarette smoke on cells and the protective effect of green tea polyphenols

      RESEARCH ON CHEMICAL INTERMEDIATES
    41. Isozaki, T; Tamura, H
      Epigallocatechin gallate (EGCG) inhibits the sulfation of 1-naphthol in a human colon carcinoma cell line, Caco-2

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    42. Suzuki, K; Yahara, S; Hashimoto, F; Uyeda, M
      Inhibitory activities of (-)-epigallocatechin-3-O-gallate against topoisomerases I and II

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    43. Okabe, S; Fujimoto, N; Sueoka, N; Suganuma, M; Fujiki, H
      Modulation of gene expression by (-)-epigallocatechin gallate in PC-9 cells using a cDNA expression array

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    44. Yamanaka, K; Mizoi, M; Kato, K; Hasegawa, A; Nakano, M; Okada, S
      Oral administration of dimethylarsinic acid, a main metabolite of inorganic arsenic, in mice promotes skin tumorigenesis initiated by dimethylbenz(a)anthracene with or without ultraviolet B as a promoter

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    45. Okabe, S; Suganuma, M; Imayoshi, Y; Taniguchi, S; Yoshida, T; Fujiki, H
      New TNF-alpha releasing inhibitors, geraniin and corilagin, in leaves of Acer nikoense, Megusurino-ki

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    46. Yoshioka, H; Senba, Y; Saito, K; Kimura, T; Hayakawa, F
      Spin-trapping study on the hydroxyl radical formed from a tea catechin-Cu(II) system

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    47. He, P; Noda, Y; Sugiyama, K
      Suppression of lipopolysaccharide-induced liver injury by various types oftea and coffee in D-Galactosamine-sensitized rats

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    48. Sugiyama, K; Noda, Y; He, P
      Suppressive effect of caffeine on hepatitis and apoptosis induced by tumornecrosis factor-alpha but not by the anti-Fas antibody, in mice

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    49. Kunishiro, K; Tai, A; Yamamoto, I
      Effects of Rooibos tea extract on antigen-specific antibody production andcytokine generation in vitro and in vivo

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    50. Katsuno, Y; Koyama, Y; Saeki, K; Sazuka, M; Ookawa, K; Isemura, M
      Apoptosis-inducing activity of a Driselase digest fraction of green tea residue

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    51. Matsuura, H; Hokura, A; Katsuki, F; Itoh, A; Haraguchi, H
      Multielement determination and speciation of major-to-trace elements in black tea leaves by ICP-AES and ICP-MS with the aid of size exclusion chromatography

      ANALYTICAL SCIENCES
    52. Hong, JT; Kim, EJ; Ahn, KS; Jung, KM; Yun, YP; Park, YK; Lee, SH
      Inhibitory effect of glycolic acid on ultraviolet-induced skin tumorigenesis in SKH-1 hairless mice and its mechanism of action

      MOLECULAR CARCINOGENESIS
    53. Trosko, JE
      Commentary: Is the concept of "tumor promotion" a useful paradigm?

      MOLECULAR CARCINOGENESIS
    54. Li, CA; Meng, XF; Winnik, B; Lee, MJ; Lu, H; Sheng, SQ; Buckley, B; Yang, CS
      Analysis of urinary metabolites of tea catechins by liquid chromatography/electrospray ionization mass spectrometry

      CHEMICAL RESEARCH IN TOXICOLOGY
    55. Chung, JY; Park, JO; Phyu, H; Dong, ZG; Yang, CS
      Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3 '-digallate

      FASEB JOURNAL
    56. Brakenhielm, E; Cao, RH; Cao, YH
      Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes

      FASEB JOURNAL
    57. Chang, CJ; Chiu, KL; Chen, YL; Yang, PW
      Effect of ethanol content on carbon dioxide extraction of polyphenols fromtea

      JOURNAL OF FOOD COMPOSITION AND ANALYSIS
    58. Katiyar, SK; Mukhtar, H
      Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress

      JOURNAL OF LEUKOCYTE BIOLOGY
    59. Liu, JD; Chen, SH; Lin, CL; Tsai, SH; Liang, YC
      Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice

      JOURNAL OF CELLULAR BIOCHEMISTRY
    60. Kavanagh, KT; Hafer, LJ; Kim, DW; Mann, KK; Sherr, DH; Rogers, AE; Sonenshein, GE
      Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture

      JOURNAL OF CELLULAR BIOCHEMISTRY
    61. Kelly, MR; Geigerman, CM; Loo, G
      Epigallocatechin gallate protects U937 cells against nitric oxide-induced cell cycle arrest and apoptosis

      JOURNAL OF CELLULAR BIOCHEMISTRY
    62. Vaidyanathan, JB; Walle, T
      Transport and metabolism of the tea flavonoid (-)-epicatechin by the humanintestinal cell line Caco-2

      PHARMACEUTICAL RESEARCH
    63. Sadzuka, Y; Sugiyama, T; Suzuki, T; Sonobe, T
      Enhancement of the activity of doxorubicin by inhibition of glutamate transporter

      TOXICOLOGY LETTERS
    64. Sugiyama, T; Sadzuka, Y; Tanaka, K; Sonobe, T
      Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin

      TOXICOLOGY LETTERS
    65. Valerio, LG; Kepa, JK; Pickwell, GV; Quattrochi, LC
      Induction of human NAD(P)H : quinone oxidoreductase (NQO1) gene expressionby the flavonol quercetin

      TOXICOLOGY LETTERS

    66. (-)-Epigallocatechin gallate - Oncolytic - Chemopreventive

      DRUGS OF THE FUTURE
    67. Lin, JK; Tsai, SH; Lin-Shiau, SY
      Antiinflammatory and antitumor effects of flavonoids and flavanoids

      DRUGS OF THE FUTURE
    68. Ruch, RJ; Trosko, JE
      Gap-junction communication in chemical carcinogenesis

      DRUG METABOLISM REVIEWS
    69. Tang, SZ; Kerry, JP; Sheehan, D; Buckley, DJ; Morrissey, PA
      Antioxidative effect of dietary tea catechins on lipid oxidation of long-term frozen stored chicken meat

      MEAT SCIENCE
    70. Record, IR; Lane, JM
      Simulated intestinal digestion of green and black teas

      FOOD CHEMISTRY
    71. Zhu, NQ; Wang, MF; Wei, GJ; Lin, JK; Yang, CS; Ho, CT
      Identification of reaction products of (-)-epigallocatechin, (-)-epigallocatechin gallate and pyrogallol with 2,2-diphenyl-1-picrylhydrazyl radical

      FOOD CHEMISTRY
    72. Inal, ME; Kahraman, A; Koken, T
      Beneficial effects of quercetin on oxidative stress induced by ultravioletA

      CLINICAL AND EXPERIMENTAL DERMATOLOGY
    73. McCarty, MF
      Insulin secretion as a determinant of pancreatic cancer risk

      MEDICAL HYPOTHESES
    74. Wong, R; Sagar, CM; Sagar, SM
      Integration of Chinese medicine into supportive cancer care: A modern rolefor an ancient tradition

      CANCER TREATMENT REVIEWS
    75. Suzuki, Y; Isemura, M
      Inhibitory effect of epigallocatechin gallate on adhesion of murine melanoma cells to laminin

      CANCER LETTERS
    76. Uesato, S; Kitagawa, Y; Kamishimoto, M; Kumagai, A; Hori, H; Nagasawa, H
      Inhibition of green tea catechins against the growth of cancerous human colon and hepatic epithelial cells

      CANCER LETTERS
    77. Hirose, M; Hoshiya, T; Mizoguchi, Y; Nakamura, A; Akagi, K; Shirai, T
      Green tea catechins enhance tumor development in the colon without effectsin the lung or thyroid after pretreatment with 1,2-dimethylhydrazine or 2,2 '-dihydroxy-di-n-propylnitrosamine in male F344 rats

      CANCER LETTERS
    78. Inoue, M; Tajima, K; Mizutani, M; Iwata, H; Iwase, T; Miura, S; Hirose, K; Hamajima, N; Tominaga, S
      Regular consumption of green tea and the risk of breast cancer recurrence:follow-up study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC), Japan

      CANCER LETTERS
    79. Kennedy, DO; Kojima, A; Yano, Y; Hasuma, T; Otani, S; Matsui-Yuasa, I
      Growth inhibitory effect of green tea extract in Ehrlich ascites tumor cells involves cytochrome c release and caspase activation

      CANCER LETTERS
    80. Ishihara, N; Chu, DC; Akachi, S; Juneja, LR
      Improvement of intestinal microflora balance and prevention of digestive and respiratory organ diseases in calves by green tea extracts

      LIVESTOCK PRODUCTION SCIENCE
    81. Hu, C; Kitts, DD
      Evaluation of antioxidant activity of epigallocatechin gallate in biphasicmodel systems in vitro

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    82. Shukla, Y; Taneja, P
      Antimutagenic effect of black tea extract using 'rodent dominant lethal mutation assay'

      TOXICOLOGY
    83. Hosaka, S; Kawa, S; Aoki, Y; Tanaka, E; Yoshizawa, K; Karasawa, Y; Hosaka, N
      Hepatocarcinogenesis inhibition by caffeine in ACI rats treated with 2-acetylaminofluorene

      FOOD AND CHEMICAL TOXICOLOGY
    84. Embola, CW; Weisburger, MC; Weisburger, JH
      Green tea and the metabolism of 2-amino-3-methylimidazo [4,5-f]quinoline in F344 rats

      FOOD AND CHEMICAL TOXICOLOGY
    85. Kim, JH; Kim, SI; Song, KS
      Prolyl endopeptidase inhibitors from green tea

      ARCHIVES OF PHARMACAL RESEARCH
    86. Sakagami, H; Arakawa, H; Maeda, M; Satoh, K; Kadofuku, T; Fukuchi, K; Gomi, K
      Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants

      ANTICANCER RESEARCH
    87. Yang, CS; Landau, JM; Huang, MT; Newmark, HL
      Inhibition of carcinogenesis by dietary polyphenolic compounds

      ANNUAL REVIEW OF NUTRITION
    88. Chhabra, SK; Yang, CS
      Tea and prostate cancer

      EPIDEMIOLOGIC REVIEWS
    89. Bhatia, N; Agarwal, C; Agarwal, R
      Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells

      NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
    90. Kang, WS; Chung, KH; Chung, JH; Lee, JY; Park, JB; Zhang, YH; Yoo, HS; Yun, YP
      Antiplatelet activity of green tea catechins is mediated by inhibition of cytoplasmic calcium increase

      JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
    91. Meng, XF; Lee, MJ; Li, C; Sheng, SQ; Zhu, NQ; Sang, SM; Ho, CT; Yang, CS
      Formation and identification of 4 '-O-methyl-(-)-epigallocatechin in humans

      DRUG METABOLISM AND DISPOSITION
    92. Walczak, J; Wood, H; Wilding, G; Williams, T; Bishop, CW; Carducci, M
      Prostate cancer prevention strategies using antiproliferative or differentiating agents

      UROLOGY
    93. Long, LH; Halliwell, B
      Antioxidant and prooxidant abilities of foods and beverages

      FLAVONOIDS AND OTHER POLYPHENOLS
    94. Robb, CS; Brown, PR
      Catechins in tea: Chemistry and analysis

      ADVANCES IN CHROMATOGRAPHY, VOL 41
    95. Zhu, M; Chen, Y; Li, RC
      Pharmacokinetics and system linearity of tea catechins in rat

      XENOBIOTICA
    96. Cuendet, M; Potterat, O; Hostettmann, K
      Flavonoids and phenylpropanoid derivatives from Campanula barbata

      PHYTOCHEMISTRY
    97. Imai, H; Osawa, K; Yasuda, H; Hamashima, H; Arai, T; Sasatsu, M
      Inhibition by the essential oils of peppermint and spearmint of the growthof pathogenic bacteria

      MICROBIOS
    98. Gupta, S; Chaudhuri, T; Ganguly, DK; Giri, AK
      Anticlastogenic effects of black tea (World blend) and its two active polyphenols theaflavins and thearubigins in vivo in Swiss albino mice

      LIFE SCIENCES
    99. Chung, LY; Cheung, TC; Kong, SK; Fung, KP; Choy, YM; Chan, ZY; Kwok, TT
      Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells

      LIFE SCIENCES
    100. Hollman, PCH
      Evidence for health benefits of plant phenols: local or systemic effects?

      JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE


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Documento generato il 18/01/21 alle ore 22:04:29