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The platelet function dose-response to abciximab during percutaneous coronary revascularization is variable
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Anticoagulant and antiplatelet drugs
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
A comparison of total hospital costs for percutaneous coronary intervention patients receiving abciximab versus tirofiban
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Severe thrombocytopenia possibly related to readministration of eptifibatide
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
A comparative study of light transmission aggregometry and automated bedside platelet function assays in patients undergoing percutaneous coronary intervention and receiving abciximab, eptifibatide, or tirofiban
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
The hunting of the Src
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Platelet antibodies and diagnosis of immune-mediated thrombocytopenia
INFUSION THERAPY AND TRANSFUSION MEDICINE-INFUSIONSTHERAPIE UND TRANSFUSIONSMEDIZIN
Demystified ... Adhesion molecule deficiencies
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
Pharmacodynamics and safety of lefradafiban, an oral platelet glycoproteinIIb/IIIa receptor antagonist, in patients with stable coronary artery disease undergoing elective angioplasty
HEART
Therapeutic potential of GP IIb/IIIa receptor antagonists in acute myocardial infarction
EXPERT OPINION ON INVESTIGATIONAL DRUGS
The anti-GPIIb-IIIa
TRANSFUSION CLINIQUE ET BIOLOGIQUE
Chemokines on the rise - MCP-1 and restenosis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Disaggregation of in vitro preformed platelet-rich clots by abciximab increases fibrin exposure and promotes fibrinolysis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Comparative antiplatelet efficacy of a novel, nonpeptide GPIIb/IIIa antagonist (XV454) and abciximab (c7E3) in flow models of thrombosis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Plasma and platelet von Willebrand factor abnormalities in patients with uremia: Lack of correlation with uremic bleeding
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
The effect of a novel glycoprotein IIb/IIIa antagonist, SR 121566A, on platelet aggregation and activation in rhesus monkeys
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
Future directions in antithrombotic therapy: Emphasis on venous thromboembolism
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
Molecular mechanisms of drug-induced thrombocytopenia
CURRENT OPINION IN HEMATOLOGY
New recommendations from the 1999 American College of Cardiology/American Heart Association acute myocardial infarction guidelines
ANNALS OF PHARMACOTHERAPY
Pharmacological control of platelet function
PHARMACOLOGICAL RESEARCH
Platelet glycoprotein IIb/IIIa blockade in acute ischemic stroke
CEREBROVASCULAR DISEASES
Future perspectives for optimizing oral antiplatelet therapy
CEREBROVASCULAR DISEASES
Radiolabeled peptide ligands for imaging thrombi and emboli
NUCLEAR MEDICINE AND BIOLOGY
Binding of a fibrinogen mimetic stabilizes integrin alpha IIb beta 3's open conformation
PROTEIN SCIENCE
2-acylimino-3H-thiazoline derivatives: A novel template for platelet GPIIb/IIIa receptor antagonists
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Platelet activation by sustained exposure to low-dose plasmin
BLOOD COAGULATION & FIBRINOLYSIS
Integrin tyrosine phosphorylation in platelet signaling
CURRENT OPINION IN CELL BIOLOGY
Quantification by flow cytometry of the efficacy of and interindividual variation of platelet inhibition induced by treatment with tirofiban and abciximab
CORONARY ARTERY DISEASE
Impact of abciximab and coronary stenting on outcomes and costs of percutaneous coronary interventions in a community hospital
CORONARY ARTERY DISEASE
Differential effects of citrate versus PPACK anticoagulation on measured platelet inhibition by abciximab, eptifibatide and tirofiban
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Elevation in serum troponin I predicts the benefit of tirofiban
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Pharmacokinetics and pharmacodynamics of low-molecular-weight heparins andglycoprotein IIb/IIIa receptor antagonists in renal failure
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Antiplatelet effect of 2-chloro-3-(4-acetophenyl)-amino-1,4-naphthoquinone(NQ301): A possible mechanism through inhibition of intracellular Ca2+ mobilization
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Activated platelets and endothelial cell interaction with neutrophils under flow conditions
INTERNAL MEDICINE
Antiplatelet mechanism of 2-chloro-3-(4-hexylphenyl)amino-1,4-naphthoquinone (NQ304), an antithrombotic agent
PHARMACOLOGY & TOXICOLOGY
Platelet activation markers and soluble adhesion molecules in patients with systemic lupus erythematosus
AUTOIMMUNITY
A common deletion at chromosomal region 17q21 in sporadic prostate tumors distal to BRCA1
GENOMICS
Integrins and signal transduction: illustration with the alpha(IIb)beta(3)integrin in platelets
M S-MEDECINE SCIENCES
Intra-arterial thrombin injection of an ascending aortic pseudoaneurysm complicated by transient ischemic attack and rescued with systemic abciximab
JOURNAL OF VASCULAR SURGERY
Long-term mortality benefit with abciximab in patients undergoing percutaneous coronary intervention
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Antiplatelet effects of abciximab, tirofiban and eptifibatide in patients undergoing coronary stenting
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Administration of abciximab to patients receiving tirofiban or eptifibatide: Effect on platelet function
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Role of platelet surface receptor abnormalities in the bleeding and thrombotic diathesis of uremic patients on hemodialysis and peritoneal dialysis
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
In vitro measurement of platelet glycoprotein IIb/IIIa receptor blockade by abciximab: interindividual variation and increased platelet secretion
HAEMATOLOGICA
Response of neonatal platelets to nitric oxide in vitro
INTENSIVE CARE MEDICINE
Risk stratification in acute coronary syndrome
HERZ
Pathophysiology of platelet activation and pharmacology of GPIIb/IIIa antagonists
HERZ
Thiosulfinates inhibit platelet aggregation and microparticle shedding at a calpain-dependent step
THROMBOSIS AND HAEMOSTASIS
Alterations of platelet aggregation kinetics with ultraviolet laser emission: The "stunned platelet" phenomenon
THROMBOSIS AND HAEMOSTASIS
Distinct domains of alpha IIb beta 3 support different aspects of outside-in signal transduction and platelet activation induced by LSARLAF, an alphaIIb beta 3 interacting peptide
THROMBOSIS AND HAEMOSTASIS
A barbourin-albumin fusion protein that is slowly cleared in vivo retains the ability to inhibit platelet aggregation in vitro
THROMBOSIS AND HAEMOSTASIS
Cytoskeletal proteins and platelet signaling
THROMBOSIS AND HAEMOSTASIS
All in the family: Primary megakaryocytes for studies of platelet alpha IIb beta(3) signaling
THROMBOSIS AND HAEMOSTASIS
Integrin activation
THROMBOSIS AND HAEMOSTASIS
Anti-GPIIb/IIIa drugs: Current strategies and future directions
THROMBOSIS AND HAEMOSTASIS
7E3 F(ab ')(2), an effective antagonist of rat alpha IIb beta 3 and alpha v beta 3, blocks in vivo thrombus formation and in vitro angiogenesis
THROMBOSIS AND HAEMOSTASIS
Platelet function inhibitors in the year 2000
THROMBOSIS AND HAEMOSTASIS
Genetic and pharmacological analyses of involvement of Src-family, Syk andBtk tyrosine kinases in platelet shape change - Src-kinases mediate integrin alpha(IIb)beta(3) inside-out signaling during shape change
THROMBOSIS AND HAEMOSTASIS
CD63 associates with the alpha(IIb)beta(3) integrin-CD9 complex on the surface of activated platelets
THROMBOSIS AND HAEMOSTASIS
Pharmacodynamic characterization of the interaction between abciximab or tirofiban with unfractionated or a low molecular weight heparin in healthy subjects
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Platelet CD62 expression and PDCFAB secretion in patients undergoing PTCA and treatment with abciximab
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Dynamic aspects of platelet adhesion under flow
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Clinical, biochemical, and molecular aspects of Glanzmann's thrombastheniain humans and dogs
VETERINARY PATHOLOGY
Variable response to the biological inhibition of platelets by abciximab in patients subjected to percutaneous coronary angioplasty
REVISTA ESPANOLA DE CARDIOLOGIA
The treatment of coronary heart disease: An update - Part 4: Acute ischaemic coronary syndromes
CURRENT MEDICAL RESEARCH AND OPINION
Risk stratification in non-ST segment elevation acute coronary syndromes with special focus on recent guidelines
PHARMACOTHERAPY
Update on strategies to improve thrombolysis for acute myocardial infarction
PHARMACOTHERAPY
Small peptide GP IIb/IIIa receptor inhibitors as upstream therapy in non-ST-segment elevation acute coronary syndromes: results of the PURSUIT, PRISM, PRISM-PLUS, TACTICS, and PARAGON trials
CURRENT OPINION IN CARDIOLOGY
Defining the role of abciximab for acute coronary syndromes: lessons from CADILLAC, ADMIRAL, GUSTO IV, GUSTO v, and TARGET
CURRENT OPINION IN CARDIOLOGY
Positional importance of Pro(53) adjacent to the Arg(49)-Gly(50)-Asp(51) sequence of rhodostomin in binding to integrin alpha IIb beta 3
BIOCHEMICAL JOURNAL
Potential role of a new anti-beta 3 integrin antibody in the development of intimal hyperplasia after vascular surgery: an in vitro smooth muscle cell model
HISTOLOGY AND HISTOPATHOLOGY
Orbofiban: An orally active GPIIB/IIIa platelet receptor antagonist
MEDICINAL RESEARCH REVIEWS
Fluorescence spectroscopic analysis of circulating platelet activation during coronary angioplasty
LASERS IN SURGERY AND MEDICINE
ESPRIT in context: pharmacology matters!
EUROPEAN HEART JOURNAL
Outcome after combined reperfusion therapy for acute myocardial infarction, combining pre-hospital thrombolysis with immediate percutaneous coronary intervention and stent
EUROPEAN HEART JOURNAL
Targeting drug delivery to radiation-induced neoantigens in tumor microvasculature
JOURNAL OF CONTROLLED RELEASE
Costs and effects of combining stenting and abciximab (ReoPro (R)) in daily practice
INTERNATIONAL JOURNAL OF CARDIOLOGY
alpha IIb's cytoplasmic domain is not required for ligand-induced clustering of integrin alpha IIb beta 3
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Binding mechanism of RGD and its mimetics to receptor GPIIb/IIIa. A theoretical study
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
Frequent co-amplification of two different regions on 17q in aneuploid breast carcinomas
CANCER GENETICS AND CYTOGENETICS
Glycoprotein IIb/IIIa inhibitors and low-molecular-weight heparins: A combined role in coronary interventions?
CLINICAL CARDIOLOGY
Antiplatelet activity of green tea catechins is mediated by inhibition of cytoplasmic calcium increase
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Eptifibatide and abciximab exhibit equivalent antiplatelet efficacy in an experimental model of stenting in both healthy volunteers and patients withcoronary artery disease
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Platelet glycoprotein IIb/IIIa-receptor inhibitors in patients with acute coronary syndromes or undergoing percutaneous coronary interventions: A review
CLINICAL THERAPEUTICS
Open-label phase I clinical study to assess the safety of intravenous eptifibatide in patients undergoing internal carotid artery angioplasty and stent placement
NEUROSURGERY
Risk of stroke associated with abciximab among patients undergoing percutaneous coronary intervention
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endotheliumin Escherichia coli endotoxin-induced shock
CRITICAL CARE MEDICINE
IIb/IIIa or not IIb/IIIa, that is adhesion
CRITICAL CARE MEDICINE
Novel platelet inhibitors
ANNUAL REVIEW OF MEDICINE
Monoclonal antibody therapy
ADVANCES IN PROTEIN CHEMISTRY, VOL 56
Synergistic outside-in regulation of platelet activation by GPIIb/IIIa ligand-induced conformation and oligomerization
THROMBOSIS RESEARCH
Methods and models to evaluate shear-dependent and surface reactivity-dependent antithrombotic efficacy
THROMBOSIS RESEARCH
Antiplatelet and antithrombotic activity of RWJ-53308, a novel orally active glycoprotein IIb/IIIa antagonist
THROMBOSIS RESEARCH
Reactivity of human platelets with immobilized fibrinogen is dictated by the chemical character of the surface
THROMBOSIS RESEARCH
Comparison of the effect of different platelet GPIIb/IIa antagonists on the dynamics of platelet/fibrin-mediated clot strength induced using thromboelastography
THROMBOSIS RESEARCH
Activation of caspase-3/caspase-3-like activity in rat cardiomyocytes by an RGD peptide, but not the GPIIb/IIIa antagonist lotrafiban
THROMBOSIS RESEARCH
Intrinsic activating properties of GP IIb/IIIa blockers
THROMBOSIS RESEARCH
Percutaneous coronary revascularisation in women
THROMBOSIS RESEARCH
GP IIB/IIIA blockers with and without thrombolytic agent in prehospital treatment of acute myocardial infarction
THROMBOSIS RESEARCH
Oral glycoprotein Ilb/IIa antagonists for unstable angina - Is there stilla chance for the oral substances?
THROMBOSIS RESEARCH