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Potential of anticytokine therapies in central nervous system ischaemia
EXPERT OPINION ON BIOLOGICAL THERAPY
Metalloproteinases in biology and pathology of the nervous system
NATURE REVIEWS NEUROSCIENCE
Cytokines and acute neurodegeneration
NATURE REVIEWS NEUROSCIENCE
Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss
AUDIOLOGY AND NEURO-OTOLOGY
Mutation frequency is reduced in the cerebellum of Big Blue (R) mice overexpressing a human wild type SOD1 gene
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Neurodegenerative disorders and ischemic brain diseases
APOPTOSIS
Adenosine in the treatment of stroke: yes, maybe, or absolutely not?
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Vatanidipine hydrochloride: a new long-lasting antihypertensive agent
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Antioxidants for CNS ischaemia and trauma
EXPERT OPINION ON THERAPEUTIC PATENTS
Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection
CELL DEATH AND DIFFERENTIATION
Stroke treatment enters the Fas lane
CELL DEATH AND DIFFERENTIATION
Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke
CELL DEATH AND DIFFERENTIATION
Targeting the central nervous system inflammatory response in ischemic stroke
CURRENT OPINION IN NEUROLOGY
The ischaemic penumbra
CURRENT OPINION IN NEUROLOGY
Cerebral ischemia and inflammation
CURRENT OPINION IN NEUROLOGY
Pharmacological treatment of traumatic brain injury - A review of agents in development
CNS DRUGS
Neuroprotection for ischaemic stroke - An unattainable goal?
CNS DRUGS
Reducing bleeding complications after thrombolytic therapy for stroke - Clinical potential of metalloproteinase inhibitors and spin trap agents
CNS DRUGS
Inhibition of post-ischemic brain injury by clusterin overexpression
NATURE MEDICINE
ORP150 protects against hypoxia/ischemia-induced neuronal death
NATURE MEDICINE
The role of the complement cascade in ischemia/reperfusion injury: Implications for neuroprotection
MOLECULAR MEDICINE
Proinflammatory cytokine expression contributes to brain injury provoked by chronic monocyte activation
MOLECULAR MEDICINE
Presence of DNA fragmentation and lack of neuroprotective effect in DFP45 knockout mice subjected to traumatic brain injury
MOLECULAR MEDICINE
Regulation of blood-brain barrier permeability
MICROCIRCULATION
Comparison of the radical trapping ability of PBN, S-PBN and NXY-059
FREE RADICAL RESEARCH
Magnetization transfer MRI: Application to treatment of middle cerebral artery occlusion in rat
JOURNAL OF MAGNETIC RESONANCE IMAGING
Use of exponential diffusion imaging to determine the age of ischemic infarcts
JOURNAL OF NEUROIMAGING
Intracerebral microdialysis and its clinical application: A review
METHODS
Quercetin, coenzyme Q(10) and L-canavanine as protective agents against lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain
PHARMACOLOGICAL RESEARCH
Neuronal NOS inhibitor that reduces oxidative DNA lesions and neuronal sensitivity increases the expression of intact c-fos transcripts after brain injury
JOURNAL OF BIOMEDICAL SCIENCE
Nerve growth factor and transforming growth factor-beta serum levels in acute stroke patients - Possible involvement of neurotrophins in cerebrovascular disease
CEREBROVASCULAR DISEASES
Combination therapy stroke trial: Recombinant tissue-type plasminogen activator with/without lubeluzole
CEREBROVASCULAR DISEASES
Platelet glycoprotein IIb/IIIa blockade in acute ischemic stroke
CEREBROVASCULAR DISEASES
The effect of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure and platelet function in acute stroke
CEREBROVASCULAR DISEASES
Relevance of experimental ischemia in cats for stroke management: A comparative reevaluation
CEREBROVASCULAR DISEASES
Cerebral ischemia: From animal studies to clinical practice. Should the methods be reviewed?
CEREBROVASCULAR DISEASES
Thrombolysis in ischaemic stroke - Present and future: Role of combined therapy
CEREBROVASCULAR DISEASES
Current status and perspectives of neuroprotection in ischemic stroke treatment
CEREBROVASCULAR DISEASES
Differential recruitment of CD8+ macrophages during Wallerian degenerationin the peripheral and central nervous system
BRAIN PATHOLOGY
Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice
NEUROBIOLOGY OF DISEASE
Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury
NEUROBIOLOGY OF DISEASE
Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease
NEUROBIOLOGY OF DISEASE
Caspase-mediated suppression of glutamate (AMPA) receptor channel activityin hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: Implications for neurological side effects of cancer therapy and neurodegenerative disorders
NEUROBIOLOGY OF DISEASE
Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum
NEUROBIOLOGY OF DISEASE
Metabolic changes in the ischemic penumbra after carotid endarterectomy instroke patients by localized in vivo proton magnetic resonance spectroscopy (H-1-MRS)
CARDIOVASCULAR SURGERY
Adult bone marrow transplantation after stroke in adult rats
CELL TRANSPLANTATION
Association of immune responses and ischemic brain infarction in rat
NEUROREPORT
Neuroprotective effects of mild hyperthermia prior to focal ischemia in conscious rats
NEUROREPORT
Delta(9)-Tetrahydrocannabinol increases brain temperature and inverts circadian rhythms
NEUROREPORT
Delayed treatment with polynitroxyl albumin reduces infarct size after stroke in rats
NEUROREPORT
Rewarming eliminates the protective effect of cooling against delayed neuronal death
NEUROREPORT
Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain
NEUROREPORT
N-methyl-D-aspartate receptor-mediated increase of neurogenesis in adult rat dentate gyrus following stroke
EUROPEAN JOURNAL OF NEUROSCIENCE
Phospholipase A(2) mediates ischemic injury in the hippocampus: a regionaldifference of neuronal vulnerability
EUROPEAN JOURNAL OF NEUROSCIENCE
MR angiographic investigation of transient focal cerebral ischemia in rat
NMR IN BIOMEDICINE
The effects of microscopic tissue parameters on the diffusion weighted magnetic resonance imaging experiment
NMR IN BIOMEDICINE
Mismatch between lactate and the apparent diffusion coefficient of water in progressive focal ischemia
NMR IN BIOMEDICINE
Hypoxia and hypoxia-inducible factor modulated gene expression in brain: involvement in neuroprotection and cell death
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
The effects of citicoline and/or MK-801 on survival, neurological and behavioral outcome of mice exposed to transient hyperglycemia and oligemic hypoxia
EUROPEAN NEUROPSYCHOPHARMACOLOGY
Nitric oxide synthase inhibitors cause motor deficits in mice
EUROPEAN NEUROPSYCHOPHARMACOLOGY
Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
IL-1 receptor antagonist prevents apoptosis and caspase-3 activation afterspinal cord injury
JOURNAL OF NEUROTRAUMA
Extracellular superoxide dismutase overexpression improves behavioral outcome from closed head injury in the mouse
JOURNAL OF NEUROTRAUMA
Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotectivefollowing traumatic brain injury in rats
JOURNAL OF NEUROTRAUMA
Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398
JOURNAL OF NEUROTRAUMA
Role of nitric oxide in the secondary expansion of a cortical brain lesionfrom cold injury
JOURNAL OF NEUROTRAUMA
Altered cellular metabolism following traumatic brain injury: A magnetic resonance spectroscopy study
JOURNAL OF NEUROTRAUMA
A new model for diffuse brain injury by rotational acceleration: II. Effects on extracellular glutamate, intracranial pressure, and neuronal apoptosis
JOURNAL OF NEUROTRAUMA
Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume
JOURNAL OF NEUROTRAUMA
The novel calpain inhibitor SJA6017 improves functional outcome after delayed administration in a mouse model of diffuse brain injury
JOURNAL OF NEUROTRAUMA
Acidosis promotes the permeability transition in energized mitochondria: Implications for reperfusion injury
JOURNAL OF NEUROTRAUMA
Improved recovery after spinal cord injury in neuronal nitric oxide synthase-deficient mice but not in TNF-alpha-deficient mice
JOURNAL OF NEUROTRAUMA
Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia
JOURNAL OF MOLECULAR NEUROSCIENCE
Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury
GLIA
Rat liver injury following normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor
FASEB JOURNAL
Oxidative stress in brain during experimental bacterial meningitis: Differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment
FREE RADICAL BIOLOGY AND MEDICINE
Neuroprotective adaptations in hibernation: Therapeutic implications for ischemia-reperfusion, traumatic brain injury and neurodegenerative diseases
FREE RADICAL BIOLOGY AND MEDICINE
Free radical spin trap alpha-phenyl-N-tert-butyl-nitron inhibits caspase-3activation and reduces brain damage following a severe forebrain ischemic injury
FREE RADICAL BIOLOGY AND MEDICINE
Neuroprotective effect of hexasulfobutylated C-60 on rats subjected to focal cerebral ischemia
FREE RADICAL BIOLOGY AND MEDICINE
Retinoic acid reduces apoptosis and oxidative stress by preservation of SOD protein level
FREE RADICAL BIOLOGY AND MEDICINE
Tumour necrosis factor-alpha is increased in the cerebrospinal fluid and serum of ischaemic stroke patients and correlates with the volume of evolving brain infarct
BIOMEDICINE & PHARMACOTHERAPY
Hypomagnesemic disorders
CRITICAL CARE CLINICS
Rapid three-dimensional diffusion MRI facilitates the study of acute stroke in mice
MAGNETIC RESONANCE IN MEDICINE
Changes in apparent diffusion coefficients of metabolites in rat brain after middle cerebral artery occlusion measured by proton magnetic resonance spectroscopy
MAGNETIC RESONANCE IN MEDICINE
Comparison of diffusion, blood oxygenation, and blood volume changes during global ischemia in rats
MAGNETIC RESONANCE IN MEDICINE
Localizing acute stroke-related EEG changes: Assessing the effects of spatial undersampling
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
Naloxone: A potential false localizing sign
AMERICAN JOURNAL OF EMERGENCY MEDICINE
Magnetic resonance prediction of outcome after thrombolytic treatment
MAGNETIC RESONANCE IMAGING
Apoptotic change and NOS activity in the experimental animal diffuse axonal injury model
YONSEI MEDICAL JOURNAL
Relationship between c-fos gene expression and delayed neuronal death in rat neonatal hippocampus following hypoxic-ischemic insult
CHINESE MEDICAL JOURNAL
Microarray analysis of hippocampal gene expression in global cerebral ischemia
ANNALS OF NEUROLOGY
Adenosine A(2A) receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage
ANNALS OF NEUROLOGY
Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders
ANNALS OF NEUROLOGY
Sequence-selective DNA binding drugs mithramycin A and chromomycin A(3) are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons
ANNALS OF NEUROLOGY
Transient focal cerebral ischemia down-regulates glutamate transporters GLT-1 and EAAC1 expression in rat brain
NEUROCHEMICAL RESEARCH
Phosphorylation of Bcl-2 and Bax proteins during hypoxia in newborn piglets
NEUROCHEMICAL RESEARCH
Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Reduction in infarct size by local estrogen does not prevent autonomic dysfunction after stroke
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
Ascorbate dynamics and oxygen consumption during arousal from hibernation in Arctic ground squirrels
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
Dual effect of HBO on cerebral infarction in MCAO rats
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY