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Plasticity in skeletal cardiac, and smooth muscle - Invited review: Pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation
JOURNAL OF APPLIED PHYSIOLOGY
Molecular medicine in the 21st century
INTERNAL MEDICINE JOURNAL
How will the human genome project change cardiovascular medicine?
HEART
The heart of genomics
NATURE MEDICINE
The role of troponin abnormalities as a cause for stunned myocardium
CORONARY ARTERY DISEASE
Low sequence variation in the gene encoding the human beta-myosin heavy chain
GENOMICS
COOH-terminal truncated human cardiac MyBP-C alters myosin filament organization
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES
Regional septal dysfunction in a three-dimensional computational model of focal myofiber disarray
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Utility of genetic approaches to common cardiovascular diseases
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Characterisation of postnatal growth of the murine heart
ANATOMY AND EMBRYOLOGY
Assignment of myotrophin to human chromosome band 7q33 -> q35 by in situ hybridization
CYTOGENETICS AND CELL GENETICS
Genetically modified animal models in cardiovascular research
REVISTA ESPANOLA DE CARDIOLOGIA
Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression
MOLECULAR AND CELLULAR BIOLOGY
Genetics of the Drosophila flight muscle myofibril: a window into the biology of complex systems
BIOESSAYS
Linkage of left ventricular contractility to chromosome 11 in humans - TheHyperGEN study
HYPERTENSION
Cardiac troponin T Arg92Trp mutation and progression from hypertrophic to dilated cardiomyopathy
CLINICAL CARDIOLOGY
Vertebrate tropomyosin: distribution, properties and function
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
Cardiomyopathies: from genetics to the prospect of treatment
LANCET
The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms
CELL
Impact of cardiac transplantation on molecular pathology of ET-1, VEGF-C, and mitochondrial metabolism and morphology in dilated versus ischemic cardiomyopathic patients
TRANSPLANTATION
Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Cardiac troponin T mutations: correlation between the type of mutation andthe nature of myofilament dysfunction in transgenic mice
JOURNAL OF PHYSIOLOGY-LONDON
Gene mutation in cardiac myosin binding protein C
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Phenotypic deficits in mice expressing a myosin binding protein C lacking the titin and myosin binding domains
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Manipulating the contractile apparatus: Genetically defined animal models of cardiovascular disease
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Beta-myosin heavy chain gene mutations and hypertrophic cardiomyopathy in Austrian children
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Alterations at the intercalated disk associated with the absence of muscleLIM protein
JOURNAL OF CELL BIOLOGY
Hypercontractile properties of cardiac muscle fibers in a knock-in mouse model of cardiac myosin-binding protein-C
JOURNAL OF BIOLOGICAL CHEMISTRY
Examining the in vivo role of the amino terminus of the essential myosin light chain
JOURNAL OF BIOLOGICAL CHEMISTRY
Effects of a cardiomyopathy-causing troponin T mutation on thin filament function and structure
JOURNAL OF BIOLOGICAL CHEMISTRY
Purkinje fibers of the avian heart express a myogenic transcription factorprogram distinct from cardiac and skeletal muscle
DEVELOPMENTAL BIOLOGY
Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant myosin-binding protein C gene
CIRCULATION
Ablation of serotonin 5-HT2B receptors in mice leads to abnormal cardiac structure and function
CIRCULATION
Sudden cardiac death, genes, and arrhythmogenesis - Consideration of new population and mechanistic approaches from a national heart, lung, and bloodinstitute workshop, part I
CIRCULATION
PKA-dependent phosphorylation of cardiac myosin binding protein C in transgenic mice
CARDIOVASCULAR RESEARCH
Opportunities for sudden death prevention: Directions for new clinical andbasic research
CARDIOVASCULAR RESEARCH
Mitochondrial pathology in cardiac failure
CARDIOVASCULAR RESEARCH
Disease-causing mutations in cardiac troponin T: Identification of a critical tropomyosin-binding region
BIOPHYSICAL JOURNAL
Independent movement of the regulatory and catalytic domains of myosin heads revealed by phosphorescence anisotropy
BIOCHEMISTRY
Construction of a human cardiovascular cDNA microarray: Portrait of the failing heart
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
From the sarcomere to the nucleus: Role of genetics and signaling in structural heart disease
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS
Cardiology in the 21st century
EUROPEAN HEART JOURNAL SUPPLEMENTS
Decoding calcium signals involved in cardiac growth and function
NATURE MEDICINE
Molecular genetics of cardiomyopathies
JOURNAL OF NUCLEAR CARDIOLOGY
Inactivation of myosin heavy chain genes in the mouse: Diverse and unexpected phenotypes
MICROSCOPY RESEARCH AND TECHNIQUE
Control of cardiac myosin heavy chain gene expression
MICROSCOPY RESEARCH AND TECHNIQUE
Molecular screening by polymerase chain reaction detects panleukopenia virus DNA in formalin-fixed hearts from cats with idiopathic cardiomyopathy and myocarditis
CARDIOVASCULAR PATHOLOGY
A genetic approach to detect muscle protein interactions in vivo
TRENDS IN CARDIOVASCULAR MEDICINE
Invasive cardiac electrophysiology in the mouse: Techniques and applications
TRENDS IN CARDIOVASCULAR MEDICINE
Cardiac electrophysiology in genetically engineered mice
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
To the heart of myofibril assembly
TRENDS IN CELL BIOLOGY
In vivo induction of cardiac Purkinje fiber differentiation by coexpression of preproendothelin-1 and endothelin converting enzyme-1
DEVELOPMENT
Physiological consequences of tropomyosin mutations associated with cardiac and skeletal myopathies
JOURNAL OF MOLECULAR MEDICINE-JMM
Echocardiographic features of genetic diseases: Part 1. Cardiomyopathy
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
A perspective: The new millennium dawns on a new paradigm for cardiology -Molecular genetics
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
The human beta-myosin heavy chain gene: Sequence diversity and functional characteristics of the protein
JOURNAL OF CELLULAR BIOCHEMISTRY
Analysis of organ physiology in transgenic mice
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Regional dysfunction correlates with myofiber disarray in transgenic mice with ventricular expression of ras
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
The "final common pathway" hypothesis and inherited cardiovascular disease- The role of cytoskeletal proteins in dilated cardiomyopathy
HERZ
Genetics and dilated cardiomyopathy: limitations of candidate gene strategies
EUROPEAN HEART JOURNAL
Genetic aspects of arrhythmias
AMERICAN JOURNAL OF MEDICAL GENETICS
Human skeletal myosin heavy chain genes are tightly linked in the order embryonic-IIa-IId/x-IIb-perinatal-extraocular
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
Functional diversity between orthologous myosins with minimal sequence diversity
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
Remodeling the cardiac sarcomere using transgenesis
ANNUAL REVIEW OF PHYSIOLOGY
Transgenic mouse model of stunned myocardium
SCIENCE
Regulation of contraction in striated muscle
PHYSIOLOGICAL REVIEWS
Autosomal dominant myopathy: Missense mutation (Glu-706 -> Lys) in the myosin heavy chain IIa gene
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Myocardial extracellular matrix and its changes in heart diseases
KARDIOLOGIYA
Effect of hypertrophic cardiomyopathy mutations in human cardiac muscle alpha-tropomyosin (Asp175Asn and Glu180Gly) on the regulatory properties of human cardiac troponin determined by in vitro motility assay
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Homozygotes for a R869G mutation in the beta-myosin heavy chain gene have a severe form of familial hypertrophic cardiomyopathy
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Deletion in the cardiac troponin I gene in a family from northern Sweden with hypertrophic cardiomyopathy
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Expression of HCM causing mutations: lessons learnt from genotype-phenotype studies of the South African founder MYH7 A797T mutation
JOURNAL OF MEDICAL GENETICS
Making matters worse for a broken heart
JOURNAL OF CLINICAL INVESTIGATION
Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B-depleted mice
JOURNAL OF CLINICAL INVESTIGATION
A functional knock-out of titin results in defective myofibril assembly
JOURNAL OF CELL SCIENCE
Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils
JOURNAL OF BIOCHEMISTRY
Functional consequences of the deletion mutation Delta Glu160 in human cardiac troponin T
JOURNAL OF BIOCHEMISTRY
The genomics of cardiovascular disorders - Therapeutic implications
DRUGS
Selective downregulation of VEGF-A(165), VEGF-R-1, and decreased capillarydensity in patients with dilative but not ischemic cardiomyopathy
CIRCULATION RESEARCH
Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy
CIRCULATION RESEARCH
Myosin heavy chain isoform expression in the failing and nonfailing human heart
CIRCULATION RESEARCH
Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy - Ca2+ regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein
CIRCULATION RESEARCH
Myosin binding protein C, a potential regulator of cardiac contractility
CIRCULATION RESEARCH
Myosin binding protein C, a phosphorylation-dependent force regulator in muscle that controls the attachment of myosin heads by its interaction with myosin S2
CIRCULATION RESEARCH
Myocardial diseases
CIRCULATION
Genetics of cardiovascular disease
CIRCULATION
Genetic manipulation of the rabbit heart via transgenesis
CIRCULATION
Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias
CARDIOVASCULAR RESEARCH
Phenotypic variation of familial hypertrophic: cardiomyopathy caused by the Phe110 -> IIe mutation in cardiac troponin T
CARDIOLOGY
A conserved negatively charged amino acid modulates function in human nonmuscle myosin IIA
BIOCHEMISTRY
Cardiogenetics in year 2000.
ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX
Role of molecular biology in identifying individuals at risk for sudden cardiac death
AMERICAN JOURNAL OF CARDIOLOGY
Genetic aspects of heart failure
EUROPEAN JOURNAL OF HEART FAILURE
Assessment of atrioventricular nodal physiology in the mouse
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
Marked variation in the cardiomyopathy associated with Friedreich's ataxia
HEART
Inherited disorders of sarcomeric proteins
CURRENT OPINION IN NEUROLOGY