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La ricerca find articoli where soggetti phrase all words 'd4T' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 64 riferimenti
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    1. Chapman, H; Kernan, M; Prisbe, E; Rohloff, J; Sparacino, M; Terhorst, T; Yu, R
      Practical synthesis, separation, and stereochemical assignment of the PMPApro-drug GS-7340

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

    2. Novel antiviral agents: phosphoramidates or mono/di/tri-phosphate esters of carbocyclic adenosine analogues

      EXPERT OPINION ON THERAPEUTIC PATENTS
    3. Ross, L; Henry, K; Paar, D; Salvato, P; Shaefer, M; Fisher, R; Liao, QM; St Clair, M
      Thymidine-analog and multi-nucleoside resistance mutations are observed inboth zidovudine-naive and zidovudine-experienced subjects with viremia after treatment with stavudine-containing regimens

      JOURNAL OF HUMAN VIROLOGY
    4. Ballatore, C; McGuigan, C; De Clercq, E; Balzarini, J
      Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    5. Zhang, LP; Price, R; Aweeka, F; Bellibas, SE; Sheiner, LB
      Making the most of sparse clinical data by using a predictive-model-based analysis, illustrated with a stavudine pharmacokinetic study

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    6. Kline, MW; Brundage, RC; Fletcher, CV; Schwarzwald, H; Calles, NR; Buss, NE; Snell, P; Delora, P; Eason, M; Jorga, K; Craig, C; Duff, F
      Combination therapy with saquinavir soft gelatin capsules in children withhuman immunodeficiency virus infection

      PEDIATRIC INFECTIOUS DISEASE JOURNAL
    7. Kaul, S; Kline, MW; Church, JA; Dunkle, LM
      Determination of dosing guidelines for stavudine (2 ',3 '-didehydro-3 '-deoxythymidine) in children with human immunodeficiency virus infection

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    8. Brossette, T; Klein, E; Creminon, C; Grassi, J; Mioskowski, C; Lebeau, L
      Synthesis of haptens for the development of immunoassays for the monitoring of intracellular anti-HIV nucleosides and nucleotides

      TETRAHEDRON
    9. Saez-Llorens, X; Nelson, RP; Emmanuel, P; Wiznia, A; Mitchell, C; Church, JA; Sleasman, J; Van Dyke, R; Richardson, CG; Cutrell, A; Spreen, W; Hetherington, S
      A randomized, double-blind study of triple nucleoside therapy of abacavir,lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children

      PEDIATRICS
    10. Allender, CJ; Brain, KR; Ballatore, C; Cahard, D; Siddiqui, A; McGuigan, C
      Separation of individual antiviral nucleotide prodrugs from synthetic mixtures using cross-reactivity of a molecularly imprinted stationary phase

      ANALYTICA CHIMICA ACTA
    11. Khandazhinskaya, AL; Shirokova, EA; Karpenko, IL; Zakirova, NF; Tarussova, NB; Krayevsky, AA
      P-(alkyl)-nucleoside 5 '-hydrogenphosphonates as depot forms of antiviral nucleotide analogues

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    12. McCarthy, WF; Gable, J; Lawrence, J; Thompson, M
      A retrospective study to determine if hydroxyurea augmentation of antiretroviral drug regimens that contain ddI and/or d4T increases the risk of developing peripheral neuropathy in HIV-1 infected individuals

      PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
    13. Siddiqui, A; McGuigan, C; Ballatore, C; Srinivasan, S; De Clercq, E; Balzarini, J
      Enhancing the aqueous solubility of d4T-based phosphoramidate prodrugs

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    14. Ewing, DF; Len, C; Mackenzie, G; Ronco, G; Villa, P
      Facile separation of chiral 1,3-dihydrobenzo[c]furan derivatives using a D-xylose moiety as a protecting group

      TETRAHEDRON-ASYMMETRY
    15. Kawaguchi, T; Kusumi, M; Hasegawa, T; Nagata, T; Saneyoshi, M; Nakano, M; Hamada, A
      Roles of hydrophobicity, protein binding and the probenecid-sensitive transport system in the cerebrospinal fluid delivery of nucleoside analogues with anti-viral activity

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    16. Schneider, B; Sarfati, R; Deville-Bonne, D; Veron, M
      Role of nucleoside diphosphate kinase in the activation of anti-HIV nucleoside analogs

      JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
    17. Grasela, DM; Stoltz, RR; Barry, M; Bone, M; Mangold, B; O'Grady, P; Raymond, R; Haworth, SJ
      Pharmacokinetics of single-dose oral stavudine in subjects with renal impairment and in subjects requiring hemodialysis

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    18. Fletcher, CV; Brundage, RC; Remmel, RP; Page, LM; Weller, D; Calles, NR; Simon, C; Kline, MW
      Pharmacologic characteristics of indinavir, didanosine, and stavudine in human immunodeficiency virus-infected children receiving combination therapy

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    19. Viso, A; Poopeiko, N; Castillon, S
      Stereoselective synthesis of nucleosides from 1-thio and 1-seleno glycosides through consecutive 1,2-migration and glycosylation under Mitsunobu conditions

      TETRAHEDRON LETTERS
    20. Palumbo, PE
      Antiretroviral therapy of HIV infection in children

      PEDIATRIC CLINICS OF NORTH AMERICA
    21. van Rossum, AMC; Niesters, HGM; Geelen, SPM; Scherpbier, HJ; Hartwig, NG; Weemaes, CMR; Veerman, AJP; Suur, MH; de Graeff-Meeder, ER; Slicker, WAT; Hop, WCJ; Osterhaus, ADME; Burger, DM; de Groot, R
      Clinical and virologic response to combination treatment with indinavir, zidovudine, and lamivudine in children with human immunodeficiency virus-1 infection: A multicenter study in The Netherlands

      JOURNAL OF PEDIATRICS
    22. Jan, ST; Zhu, Z; Tai, HL; Shih, MJ; Venkatachalam, TK; Uckun, FM
      AZT-5 '-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agent

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    23. Ballatore, C; McGuigan, C; De Clercq, E; Balzarini, J
      An in situ pig liver esterase assay as a useful predictive tool for the likely in vitro anti viral activity of phosphoramidate pro-drugs.

      NUCLEOSIDES & NUCLEOTIDES
    24. Egron, D; Perigaud, C; Gosselin, G; Aubertin, AM; Imbach, JL
      Synthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3 '-azido-2 ',3 '-dideoxythymidine

      NUCLEOSIDES & NUCLEOTIDES
    25. Ewing, DF; Fahmi, NE; Len, C; Mackenzie, G; Ronco, G; Villa, P; Shaw, G
      Nucleoside analogues with a novel glycone based on the benzo[c]furan core

      NUCLEOSIDES & NUCLEOTIDES
    26. Cardona, VMF; Ayi, AI; Aubertin, AM; Guedj, R
      Synthesis and anti-HIV activity of some novel arylphosphate and H-phosphonate derivatives of 3 '-azido-2 ',3 '-dideoxythymidine and 2 ',3 '-didehydro-2 ',3 '-dideoxythymidine

      ANTIVIRAL RESEARCH
    27. Elion, R; Kaul, S; Knupp, C; Adler, M; Cross, AP; Dunkle, LM; Kelleher, T
      The safety profile and antiviral activity of the combination of stavudine,didanosine, and nelfinavir in patients with HIV infection

      CLINICAL THERAPEUTICS
    28. Balzarini, J; Naesens, L; Aquaro, S; Knispel, T; Perno, CF; De Clercq, E; Meier, C
      Intracellular metabolism of CycloSaligenyl 3 '-azido-2 ',3 '-dideoxythymidine monophosphate, a prodrug of 3 '-azido-2 ',3 '-dideoxythymidine (zidovudine)

      MOLECULAR PHARMACOLOGY
    29. TURRIZIANI O; SIMEONI E; DIANZANI F; ANTONELLI G
      ANTI-HIV ANTIVIRAL ACTIVITY OF STAVUDINE IN A THYMIDINE KINASE-DEFICIENT CELLULAR-LINE

      Antiviral therapy
    30. EGRON D; LEFEBVRE I; PERIGAUD C; BELTRAN T; POMPON A; GOSSELIN G; AUBERTIN AM; IMBACH JL
      ANTI-HIV PRONUCLEOTIDES - DECOMPOSITION PATHWAYS AND CORRELATION WITHBIOLOGICAL-ACTIVITIES

      Bioorganic & medicinal chemistry letters
    31. MCGUIGAN C; CAHARD D; BALLATORE C; SIDDIQUI A; DECLERCQ E; BALZARINI J
      LACTATE CANNOT SUBSTITUTE FOR ALANINE IN D4T-BASED ANTI-HIV NUCLEOTIDE PRODRUGS - DESPITE EFFICIENT ESTERASE-MEDIATED HYDROLYSIS

      Bioorganic & medicinal chemistry letters
    32. Venkatachalam, TK; Tai, HL; Vig, R; Chen, CL; Jan, ST; Uckun, FM
      Enhancing effects of a mono-bromo substitution at the para position of thephenyl moiety on the metabolism and anti-HIV activity of D4T-phenyl methoxyalaninyl phosphate derivatives

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    33. VIG R; VENKATACHALAM TK; JAN ST; UCKUN FM
      ARYL PHOSPHATE DERIVATIVES OF 3'-DEOXYTHYMIDINE ARE NOT POTENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENTS

      Antiviral chemistry & chemotherapy
    34. VIG R; VENKATACHALAM TK; UCKUN FM
      D4T-5'-[P-BROMOPHENYL METHOXYALANINYL PHOSPHATE] AS A POTENT AND NONTOXIC ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENT

      Antiviral chemistry & chemotherapy
    35. RENOUDGRAPPIN M; FOSSEY C; FONTAINE G; LADUREE D; AUBERTIN AM; KIRN A
      IMIDAZO[1,5-B]PYRIDAZINE-D4T CONJUGATES - SYNTHESIS AND ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS EVALUATION

      Antiviral chemistry & chemotherapy
    36. MCGUIGAN C; TSANG HW; SUTTON PW; DECLERCQ E; BALZARINI J
      SYNTHESIS AND ANTI-HIV ACTIVITY OF SOME NOVEL CHAIN-EXTENDED PHOSPHORAMIDATE DERIVATIVES OF D4T (STAVUDINE) - ESTERASE HYDROLYSIS AS A RAPID PREDICTIVE TEST FOR ANTIVIRAL POTENCY

      Antiviral chemistry & chemotherapy
    37. McGuigan, C; Sutton, PW; Cahard, D; Turner, K; O'Leary, G; Wang, Y; Gumbleton, M; De Clercq, E; Balzarini, J
      Synthesis, anti-human immunodeficiency virus activity and esterase lability of some novel carboxylic ester-modified phosphoramidate derivatives of stavudine (d4T)

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    38. RAO SN
      CONFORMATIONAL STUDIES ON NUCLEOSIDES WITH FURANOSE RING MODIFICATIONS - 1

      Nucleosides & nucleotides
    39. MEASURES PT; MORT KA; COOPER DL; ALLAN NL
      A QUANTUM MOLECULAR SIMILARITY APPROACH TO ANTI-HIV ACTIVITY

      Journal of molecular structure. Theochem
    40. KAUL S; CHRISTOFALO B; RAYMOND RH; STEWART MB; MACLEOD CM
      EFFECT OF FOOD ON THE BIOAVAILABILITY OF STAVUDINE IN SUBJECTS WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

      Antimicrobial agents and chemotherapy
    41. WEINBERG RS; CHUSID ED; GALPERIN Y; THOMSON JC; CHEUNG T; SACKS HS
      EFFECT OF ANTIVIRAL DRUGS AND HEMATOPOIETIC GROWTH-FACTORS ON IN-VITRO ERYTHROPOIESIS

      The Mount Sinai journal of medicine
    42. THOMAS SA; SEGAL MB
      THE TRANSPORT OF THE ANTI-HIV DRUG, 2',3'-DIDEHYDRO-3'DEOXYTHYMIDINE (D4T), ACROSS THE BLOOD-BRAIN AND BLOOD CEREBROSPINAL-FLUID BARRIERS

      British Journal of Pharmacology
    43. MCGUIGAN C; VELAZQUEZ S; DECLERCQ E; BALZARINI J
      SYNTHESIS AND EVALUATION OF 5-HALO 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES AND THEIR BLOCKED PHOSPHORAMIDATES AS POTENTIAL ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENTS - AN EXAMPLE OF KINASE BYPASS

      Antiviral chemistry & chemotherapy
    44. MANOUILOV KK; XU ZS; MANOUILOVA LS; BOUDINOT FD; SCHINAZI RF; CHU CK
      LYMPHATIC TARGETING OF ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS NUCLEOSIDES - PHARMACOKINETICS OF 3'-DEOXY-2',3'-DIDEHYDROTHYMIDINE AFTER INTRAVENOUS AND ORAL-ADMINISTRATION OF DIPALMITOYLPHOSPHATIDYL PRODRUG TO MICE

      Antiviral chemistry & chemotherapy
    45. MEIER C; LOREY M; DECLERCQ E; BALZARINI J
      ,3'-DIDEOXY-2',3'-DIDEHYDROYTHYMIDINEMONOPHOSPHATE (CYCLOSAL-D4TMP) -A NEW PRO-NUCLEOTIDE APPROACH

      Nucleosides & nucleotides
    46. YANG Z; BRUNDAGE RC; BARBHAIYA RH; SAWCHUK RJ
      MICRODIALYSIS STUDIES OF THE DISTRIBUTION OF STAVUDINE INTO THE CENTRAL-NERVOUS-SYSTEM IN THE FREELY-MOVING RAT

      Pharmaceutical research
    47. RANA KZ; DUDLEY MN
      CLINICAL PHARMACOKINETICS OF STAVUDINE

      Clinical pharmacokinetics
    48. DRAKE RR; MCMASTERS R; KRISA S; HUME SD; RECHTIN TM; SAYLORS RL; CHIANG YW; GOVINDARAJAN R; MUNSHI NC
      METABOLISM AND ACTIVITIES OF 3'-AZIDO-2',3'-DIDEOXYTHYMIDINE AND 2',3'-DIDEHYDRO-2',3'-DIDEOXYTHYMIDINE IN HERPESVIRUS THYMIDINE KINASE TRANSDUCED T-LYMPHOCYTES

      Antiviral research
    49. PRAGNACHARYULU PVP; ABUSHANAB E
      STEREOSPECIFIC SYNTHESIS OF 2'-DEOXY PYRIMIDINE AND 5,6-DIHYDRO 5-HYDROXY THYMIDINE NUCLEOSIDES

      Tetrahedron letters
    50. SPRUANCE SL; PAVIA AT; MELLORS JW; MURPHY R; GATHE J; STOOL E; JEMSEK JG; DELLAMONICA P; CROSS A; DUNKLE L
      CLINICAL EFFICACY OF MONOTHERAPY WITH STAVUDINE COMPARED WITH ZIDOVUDINE IN HIV-INFECTED, ZIDOVUDINE-EXPERIENCED PATIENTS - A RANDOMIZED, DOUBLE-BLIND, CONTROLLED TRIAL

      Annals of internal medicine
    51. DOBKIN JF
      3RD RETROVIRUS CONFERENCE - MAGIC

      Complications in surgery
    52. MCGUIGAN C; SALGADO A; YARNOLD C; HARRIES TY; DECLERCQ E; BALZARINI J
      NOVEL NUCLEOSIDE PHOSPHORAMIDATES AS INHIBITORS OF HIV - STUDIES ON THE STEREOCHEMICAL REQUIREMENTS OF THE PHOSPHORAMIDATE AMINO-ACID

      Antiviral chemistry & chemotherapy
    53. MCGUIGAN C; CAHARD D; SALGADO A; DECLERCQ E; BALZARINI J
      PHOSPHORAMIDATES AS POTENT PRODRUGS OF ANTI-HIV NUCLEOTIDES - STUDIESIN THE AMINO REGION

      Antiviral chemistry & chemotherapy
    54. NAVE JF; NEISES B; ESCHBACH A
      STUDY OF ANALOGS OF THYMIDINE-5'-MONOPHOSPHATE AND THYMIDINE AS SUBSTRATES OR INHIBITORS OF CHICK-EMBRYO LIVER THYMIDYLATE KINASE

      Nucleosides & nucleotides
    55. MEIER C
      EOS-5'-O-YL-4H-1,3,2-BENZODIOXAPHOSPHININ-2-OXIDES - A NEW CONCEPT FOR LIPOPHILIC, POTENTIAL PRODRUGS OF BIOLOGICALLY-ACTIVE NUCLEOSIDE MONOPHOSPHATES

      Angewandte Chemie, International Edition in English
    56. DISCORDIA RP
      SYNTHESIS OF 1'-[C-14]-STAVUDINE(R) (D4T)

      Journal of labelled compounds & radiopharmaceuticals
    57. SUJINO K; YOSHIDA T; SUGIMURA H
      FACILE SYNTHESIS OF 2',3'-UNSATURATED NUCLEOSIDES FROM 2-DEOXYRIBOSE

      Tetrahedron letters
    58. AHLUWALIA GS; GAG WY; MITSUYA H; JOHNS DG
      2',3'-DIDEHYDRO-3'-DEOXYTHYMIDINE - REGULATION OF ITS METABOLIC-ACTIVATION BY MODULATORS OF THYMIDINE-5'-TRIPHOSPHATE BIOSYNTHESIS

      Molecular pharmacology
    59. CLIVE DLJ; WICKENS PL; SGARBI PWM
      SYNTHESIS OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES BY REACTION OF 5'-PROTECTED NUCLEOSIDE 2',3'-DIMESYLATES WITH TELLURIDE DIANION - A GENERAL-ROUTE FROM CIS VICINAL DIOLS TO OLEFINS

      Journal of organic chemistry
    60. LEA AP; FAULDS D
      STAVUDINE - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES AND CLINICAL POTENTIAL IN HIV-INFECTION

      Drugs
    61. KAUL S; MUMMANENI V; BARBHAIYA RH
      DOSE PROPORTIONALITY OF STAVUDINE IN HIV-SEROPOSITIVE ASYMPTOMATIC SUBJECTS - APPLICATION TO BIOEQUIVALENCE ASSESSMENT OF VARIOUS CAPSULE FORMULATIONS

      Biopharmaceutics & drug disposition
    62. SIDWELL RW; WARREN RP; OKLEBERRY K; BURGER RA; MORREY JD
      EFFECT OF THE COMBINATION OF INTERFERON-ALPHA AND STAVUDINE ON FRIEND-VIRUS INFECTIONS IN (B10.A X A.BY)F-1 MICE

      The Journal of infectious diseases
    63. ABRAHAM TW; WAGNER CR
      A PHOSPHORAMIDITE-BASED SYNTHESIS OF PHOSPHORAMIDATE AMINO-ACID DIESTERS OF ANTIVIRAL NUCLEOSIDES

      Nucleosides & nucleotides
    64. BAWDON RE; KAUL S; SOBHI S
      THE EX-VIVO TRANSFER OF THE ANTI-HIV NUCLEOSIDE COMPOUND D4T IN THE HUMAN PLACENTA

      Gynecologic and obstetric investigation


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Documento generato il 26/05/20 alle ore 09:07:19