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    1. Danchin, N
      Recent advances in cardioprotection during myocardial revascularization procedures: benefit of a metabolic intervention

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    2. Karmazyn, M
      Therapeutic potential of Na-H exchange inhibitors for the treatment of heart failure

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    3. Zarse, M; Stellbrink, C; Athanatou, E; Robert, J; Schotten, U; Hanrath, P
      Verapamil prevents stretch-induced shortening of atrial effective refractory period in Langendorff-perfused rabbit heart

      JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
    4. Guzman-Perez, A; Wester, RT; Allen, MC; Brown, JA; Buchholz, AR; Cook, ER; Day, WW; Hamanaka, ES; Kennedy, SP; Knight, DR; Kowalczyk, PJ; Marala, RB; Mularski, CJ; Novomisle, WA; Ruggeri, RB; Tracey, WR; Hill, RJ
      Discovery of zoniporide: A potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    5. Zeymer, U; Suryapranata, H; Monassier, JP; Opolski, G; Davies, J; Rasmanis, G; Linssen, G; Tebbe, U; Schroder, R; Tiemann, R; Maching, T; Neuhaus, KL
      The Na+/H+ exchange inhibitor eniporide as an adjunct to early reperfusiontherapy for acute myocardial infarction - Results of the evaluation of thesafety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial

      JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
    6. Menown, IBA; Adgey, AAJ
      Cardioprotective therapy and sodium-hydrogen exchange inhibition: Current concepts and future goals

      JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
    7. Miura, T; Liu, YG; Goto, M; Tsuchida, A; Miki, T; Nakano, A; Nishino, YH; Ohnuma, Y; Shimamoto, K
      Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection byNa+-H+ exchange inhibition against ischemia/reperfusion injury

      JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
    8. Gross, GJ; Gumina, RJ
      Cardioprotective effects of Na+/H+ exchange inhibitors

      DRUGS OF THE FUTURE
    9. Symons, JD; Schaefer, S
      Na+/H+ exchange subtype 1 inhibition reduces endothelial dysfunction in vessels from stunned myocardium

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    10. Kusumoto, K; Haist, JV; Karmazyn, M
      Na+/H+ exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    11. Hotta, Y; Ishikawa, N; Ohashi, N; Matsui, K
      Effects of SM-20550, a selective Na+-H+ exchange inhibitor, on the ion transport of myocardial mitochondria

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    12. Yamamoto, S; Matsui, K; Itoh, N; Ohashi, N
      The effect of an Na+/H+ exchange inhibitor, SM-20550, on ischemia/reperfusion-induced endothelial dysfunction in isolated perfused rat hearts

      INTERNATIONAL JOURNAL OF TISSUE REACTIONS-EXPERIMENTAL AND CLINICAL ASPECTS
    13. Hotta, Y; Nakagawa, J; Ishikawa, N; Wakida, Y; Ando, H; Takeya, K; Ohashi, N; Matsui, K
      Protective effect of SM-20550, a selective Na+-H+ exchange inhibitor, on ischemia-reperfusion-injured hearts

      JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
    14. Kovar, A; Peters, T; Beier, N; Derendorf, H
      Pharmacokinetic/pharmacodynamic evaluation of the NHE inhibitor eniporide

      JOURNAL OF CLINICAL PHARMACOLOGY
    15. Knight, DR; Smith, AH; Flynn, DM; Macandrew, JT; Ellergy, SS; Kong, JX; Marala, RB; Wester, RT; Guzman-Perez, A; Hill, RJ; Magee, WP; Tracey, WR
      A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reducesischemic myocardial injury in vitro and in vivo

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    16. Ahmad, S; Doweyko, LM; Dugar, S; Grazier, N; Ngu, K; Wu, SC; Yost, KJ; Chen, BC; Gougoutas, JZ; DiMarco, JD; Lan, SJ; Gavin, BJ; Chen, AY; Dorso, CR; Serafino, R; Kirby, M; Atwal, KS
      Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1

      JOURNAL OF MEDICINAL CHEMISTRY
    17. Kawamoto, T; Kimura, H; Kusumoto, K; Fukumoto, S; Shiraishi, M; Watanabe, T; Sawada, H
      Potent and selective inhibition of the human Na+/H+ exchanger isoform NHE1by a novel aminoguanidine derivative T-162559

      EUROPEAN JOURNAL OF PHARMACOLOGY
    18. Karmazyn, M; Sostaric, JV; Gan, XT
      The myocardial Na+/H+ exchanger - A potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation ofpostinfarction heart failure

      DRUGS
    19. Gazmuri, RJ; Ayoub, IM; Hoffner, E; Kolarova, JD
      Successful ventricular defibrillation by the selective sodium-hydrogen exchanger isoform-1 inhibitor cariporide

      CIRCULATION
    20. Allen, DG; Xiao, XH
      Na+ entry during ischemia, reperfusion and preconditioning

      CARDIOVASCULAR RESEARCH
    21. Hoshino, K; Avkiran, M
      Effects of moderate hypothermia on sarcolemmal Na+/H+ exchanger activity and its inhibition by cariporide in cardiac ventricular myocytes

      BRITISH JOURNAL OF PHARMACOLOGY
    22. Redlin, M; Werner, J; Habazettl, H; Griethe, W; Kuppe, H; Pries, AR
      Cariporide (HOE 642) attenuates leukocyte activation in ischemia and reperfusion

      ANESTHESIA AND ANALGESIA
    23. Baumgarth, M; Gericke, R
      A concise and efficient synthesis of [2-methyl-5-methylsulfonyl-4-(pyrrol-1-yl)benzoyl]guanidinium methanesulfonate (eniporide)

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    24. Karmazyn, M
      Pharmacology and clinical assessment of cariporide for the treatment coronary artery diseases

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    25. Bonnet, U; Bingmann, D; Wiemann, M
      Intracellular pH modulates spontaneous and epileptiform bioelectric activity of hippocampal CA3-neurones

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    26. Hale, SL; Kloner, RA
      Effect of combined K-ATP channel activation and Na+/H+ exchange inhibitionon infarct size in rabbits

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    27. Yoshida, H; Karmazyn, M
      Na+/H+ exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    28. Otani, H; Uchiyama, T; Yamamura, T; Nakao, Y; Hattori, R; Ninomiya, H; Kido, M; Kawaguchi, H; Osako, M; Imamura, H
      Effects of the Na+/H+ exchange inhibitor cariporide (HOE 642) on cardiac function and cardiomyocyte cell death in rat ischaemic-reperfused heart

      CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
    29. Yellon, DM; Baxter, GF
      Sodium-hydrogen exchange in myocardial reperfusion injury

      LANCET
    30. Sharma, A; Singh, M
      Na+/H+ exchanger: An emerging therapeutic target in cardiovascular disorders

      DRUGS OF TODAY
    31. Aihara, K; Hisa, H; Sato, T; Yoneyama, F; Sasamori, J; Yamaguchi, F; Yoneyama, S; Mizuno, Y; Takahashi, A; Nagai, A; Kimura, T; Kogi, K; Satoh, S
      Cardioprotective effect of TY-12533, a novel Na+/H+ exchange inhibitor, onischemia/reperfusion injury

      EUROPEAN JOURNAL OF PHARMACOLOGY
    32. Jandeleit-Dahm, K; Hannan, KM; Farrelly, CA; Allen, TJ; Rumble, JR; Gilbert, RE; Cooper, ME; Little, PJ
      Diabetes-induced vascular hypertrophy is accompanied by activation of Na+-H+ exchange and prevented by Na+-H+ exchange inhibition

      CIRCULATION RESEARCH
    33. Theroux, P; Chaitman, BR; Danchin, N; Erhardt, L; Meinertz, T; Schroeder, JS; Tognoni, G; White, HD; Willerson, JT; Jessel, A
      Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations - Main results of the GUARDIAN trial

      CIRCULATION
    34. Theroux, P
      Myocardial cell protection - A challenging time for action and a challenging time for clinical research

      CIRCULATION
    35. Rupprecht, HJ; vom Dahl, J; Terres, W; Seyfarth, KM; Richardt, G; Schultheiss, HP; Buerke, M; Sheehan, FH; Drexler, H
      Cardioprotective effects of the Na+/H+ exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA

      CIRCULATION
    36. Hashimoto, K; Sugiyama, A; Xue, YX; Aye, NN; Yamada, C; Chino, D
      Antiarrhythmic effects of Na+/H+ exchange inhibitors

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    37. Scholz, W
      The Na+/H+ exchange inhibitor cariporide: preclinical profile and approachto clinical development

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    38. Harris, C; Fliegel, L
      Amiloride and the Na+/H+ exchanger protein: Mechanism and significance of inhibition of the Na+/H+ exchanger (Review)

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    39. Karmazyn, M
      Mechanisms of protection of the ischemic and reperfused myocardium by sodium-hydrogen exchange inhibition

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    40. Sugiyama, A; Aye, NN; Sawada, N; Hashimoto, K
      Cariporide, a highly selective Na+/H+ exchange inhibitor, suppresses the reperfusion-induced lethal arrhythmias and "overshoot" phenomenon of creatine phosphate in situ rat heart

      JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
    41. Hartmann, M; Decking, UKM
      Blocking Na+-H+ exchange by cariporide reduces Na+-overload in ischemia and is cardioprotective

      JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
    42. Karmazyn, M; Gan, XHT; Humphreys, RA; Yoshida, H; Kusumoto, K
      The myocardial Na+-H+ exchange - Structure, regulation, and its role in heart disease

      CIRCULATION RESEARCH
    43. Aye, NN; Komori, S; Hashimoto, K
      Effects and interaction, of cariporide and preconditioning on cardiac arrhythmias and infarction in rat in vivo

      BRITISH JOURNAL OF PHARMACOLOGY
    44. LINZ W; ALBUS U; CRAUSE P; JUNG W; WEICHERT A; SCHOLKENS BA; SCHOLZ W
      DOSE-DEPENDENT REDUCTION OF MYOCARDIAL INFARCT MASS IN RABBITS BY THENHE-1 INHIBITOR CARIPORIDE (HOE-642)

      Clinical and experimental hypertension
    45. Symons, JD; Correa, SD; Schaefer, S
      Na-H exchange inhibition with cariporide limits functional impairment caused by repetitive ischemia

      JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
    46. DHEIN S; KRUSEMANN K; ENGELMANN F; GOTTWALD M
      EFFECTS OF THE TYPE-1 NA+ H+-EXCHANGE INHIBITOR CARIPORIDE (HOE-642) ON CARDIAC TISSUE/

      Naunyn-Schmiedeberg's archives of pharmacology
    47. MYERS ML; FARHANGKHOEE P; KARMAZYN M
      HYDROGEN-PEROXIDE INDUCED IMPAIRMENT OF POSTISCHEMIC VENTRICULAR-FUNCTION IS PREVENTED BY THE SODIUM-HYDROGEN EXCHANGE INHIBITOR HOE-642 (CARIPORIDE)

      Cardiovascular Research
    48. CHAKRABARTI S; HOQUE ANE; KARMAZYN M
      A RAPID ISCHEMIA-INDUCED APOPTOSIS IN ISOLATED RAT HEARTS AND ITS ATTENUATION BY THE SODIUM-HYDROGEN EXCHANGE INHIBITOR HOE-642 (CARIPORIDE)

      Journal of Molecular and Cellular Cardiology
    49. AYE NN; XUE YX; HASHIMOTO K
      ANTIARRHYTHMIC EFFECTS OF CARIPORIDE, A NOVEL NA-H+ EXCHANGE INHIBITOR, ON REPERFUSION VENTRICULAR ARRHYTHMIAS IN RAT HEARTS()

      European journal of pharmacology
    50. HOQUE ANE; KARMAZYN M
      EFFECT OF SODIUM-HYDROGEN EXCHANGE INHIBITION ON FUNCTIONAL AND METABOLIC IMPAIRMENT PRODUCED BY OXIDATIVE STRESS IN THE ISOLATED RAT-HEART

      Canadian journal of physiology and pharmacology
    51. WEICHERT A; FABER S; JANSEN HW; SCHOLZ W; LANG HJ
      SYNTHESIS OF THE HIGHLY SELECTIVE NA+ H+ EXCHANGE INHIBITORS CARIPORIDE MESILATE AND (3-METHANESULFONYL-4-PIPERIDINO-BENZOYL) GUANIDINE METHANESULFONATE/

      Arzneimittel-Forschung


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/02/20 alle ore 14:51:28