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Genetic aspects in acquired long QT syndrome - a piece in the puzzle
EUROPEAN HEART JOURNAL SUPPLEMENTS
Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes
EUROPEAN HEART JOURNAL SUPPLEMENTS
Potential mechanisms of adverse pulmonary and cardiovascular effects of particulate air pollution (PM10)
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
Genetic variations in five genes involved in the excitement of cardiomyocytes
JOURNAL OF HUMAN GENETICS
Multiple single-nucleotide polymorphisms (SNPs) in the Japanese populationin six candidate genes for long QT syndrome
JOURNAL OF HUMAN GENETICS
Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome
JOURNAL OF HUMAN GENETICS
Influence of transmural repolarization gradients on the electrophysiology and pharmacology of ventricular myocardium. Cellular basis for the Brugada and long-QT syndromes
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
Response of the QT interval to mental and physical stress in types LQT1 and LQT2 of the long QT syndrome
HEART
Peripheral channelopathies as targets for potassium channel openers
EXPERT OPINION ON INVESTIGATIONAL DRUGS
The long QT syndrome
EUROPACE
Acute canine model for drug-induced torsades de pointes in drug safety evaluation - Influences of anesthesia and validation with quinidine and astemizole
TOXICOLOGICAL SCIENCES
Lethal cardiac tachyarrhythmia in a patient with neonatal carnitine-acylcarnitine translocase deficiency
PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
Development and evaluation of high throughput functional assay methods forhERG potassium channel
JOURNAL OF BIOMOLECULAR SCREENING
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome
NATURE MEDICINE
Cocaine, ethanol, and cocaethylelae cardiotoxity in an animal model of cocaine and ethanol abuse
ACADEMIC EMERGENCY MEDICINE
Inherited sodium channelopathies: Novel therapeutic and proarrhythmic molecular mechanisms
TRENDS IN CARDIOVASCULAR MEDICINE
Possible bradycardic mode of death and successful pacemaker treatment in alarge family with features of long QT syndrome type 3 and Brugada syndrome
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
Ventricular tachycardia or conduction disease: What is the mechanism of death associated with SCN5A?
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
Sodium channel inactivation abnormalities associated with heart disease: Ionic remodeling and arrhythmogenic channelopathies
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
Evidence for a single nucleotide polymorphism in the KCNQ1 potassium channel that underlies susceptibility to life-threatening arrhythmias
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
Ion channels in disease
CURRENT OPINION IN PEDIATRICS
Pharmaco genetics: an opportunity for a safer and more efficient pharmacotherapy
JOURNAL OF INTERNAL MEDICINE
Dietary polyunsaturated fatty acid and antioxidant modulation of vascular dysfunction in the spontaneously hypertensive rat
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
Long QT syndrome.
ARCHIVES DE PEDIATRIE
Mortality in pediatric epilepsy
PEDIATRIC NEUROLOGY
Asthma and scuba diving - Absolute contraindication? in all asthma patients?
REVUE DES MALADIES RESPIRATOIRES
A founder mutation of the potassium channel KCNQ1 in long QT syndrome - Implications for estimation of disease prevalence and molecular diagnostics
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Interrelationship between cardiac structure and function and incidence of arrhythmia in peritoneal dialysis patients
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
Prolonged QT interval and sudden infant death - report of two cases
FORENSIC SCIENCE INTERNATIONAL
Clozapine and sudden death
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain
JOURNAL OF NEUROSCIENCE
Molecular autopsy of sudden unexplained death in the young
AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY
Morphological algebraic models of the TU-wave patterns/in idiopathic long QT syndrome
INTERNATIONAL JOURNAL OF CARDIOLOGY
Drug block of I-kappa r: Model systems and relevance to human arrhythmias
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Bradycardia-induced long QT syndrome caused by a de novo missense mutationin the S2-S3 inner loop of HERG
AMERICAN JOURNAL OF MEDICAL GENETICS
Cardiac arrhythmias in F-16 pilots during aerial combat maneuvers (ACMS): A descriptive study focused on G-level acceleration
AVIATION SPACE AND ENVIRONMENTAL MEDICINE
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome
CELL
Cardiovascular effects of air pollution: What to measure in ECG?
ENVIRONMENTAL HEALTH PERSPECTIVES
Air pollution and blood markers of cardiovascular risk
ENVIRONMENTAL HEALTH PERSPECTIVES
Genotype and severity of long QT syndrome
DRUG METABOLISM AND DISPOSITION
Role of alpha 1-blockade in congenital long QT syndrome - Investigation byexercise stress test
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
Correlations between electrophysiological heart parameters, blood gas composition and hemodynamic parameters in patients with chronic obstructive bronchitis
TERAPEVTICHESKII ARKHIV
Dominant negative guard cell K+ channel mutants reduce inward-rectifying K+ currents and light-induced stomatal opening in arabidopsis
PLANT PHYSIOLOGY
Molecular cloning and expression of cERG, the ether a go-go-related gene from canine myocardium
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Inhibition of human ether-a-go-go potassium channels by cocaine
MOLECULAR PHARMACOLOGY
Functional characterization of the C-terminus of the human ether-a-go-go-related gene K+ channel (HERG)
JOURNAL OF PHYSIOLOGY-LONDON
Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade
JOURNAL OF PHYSIOLOGY-LONDON
Actions of pyrethroid insecticides on sodium currents, action potentials, and contractile rhythm in isolated mammalian ventricular myocytes and perfused hearts
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Hypophosphatemia and hypomagnesemia induced by cooling in patients with severe head injury
JOURNAL OF NEUROSURGERY
Defective ion channel function in the long QT syndrome: Multiple unexpected mechanisms
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Mutation detection in long QT syndrome: a comprehensive set of primers andPCR conditions
JOURNAL OF MEDICAL GENETICS
HERG K+ channels activation during beta(1) integrin-mediated adhesion to fibronectin induces an up-regulation of alpha(v)beta(3) integrin in the preosteoclastic leukemia cell line FLG 29.1
JOURNAL OF BIOLOGICAL CHEMISTRY
Location and orientation of minK within the I-Ks potassium channel complex
JOURNAL OF BIOLOGICAL CHEMISTRY
Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2
JOURNAL OF BIOLOGICAL CHEMISTRY
An amino acid residue whose change by mutation affects drug binding to theHERG channel
FEBS LETTERS
Principles in pharmacogenetics
EPILEPSIA
Familial aggregation of QT-interval variability in a general population: results from the NHLBI Family Heart Study
CLINICAL GENETICS
Homozygous SCN5A mutation in long-QT syndrome with functional two-to-one atrioventricular block
CIRCULATION RESEARCH
Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis
CIRCULATION RESEARCH
Do all voltage-gated potassium channels use MiRPs?
CIRCULATION RESEARCH
Long-QT syndrome-associated missense mutations in the pore helix of the HERG potassium channel
CIRCULATION
Clinical implications for affected parents and siblings of probands with long-QT syndrome
CIRCULATION
Divergent expression of delayed rectifier K+ channel subunits during mouseheart development
CARDIOVASCULAR RESEARCH
Multiple interactions determine cellular electrical processes in the multicellular tissue
CARDIOVASCULAR RESEARCH
Pharmacogenetics and drug-induced arrhythmias
CARDIOVASCULAR RESEARCH
Inhibition of HERG potassium channel current by the Class 1a antiarrhythmic agent disopyramide
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Genotype and severity of long QT syndrome
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels
ANESTHESIOLOGY
Molecular biology and the prolonged QT syndromes
AMERICAN JOURNAL OF MEDICINE
Genetic susceptibility to adverse drug reactions
TRENDS IN PHARMACOLOGICAL SCIENCES
HERG K+ channels: friend and foe
TRENDS IN PHARMACOLOGICAL SCIENCES
Medical consequences of alcohol abuse
ALCOHOL RESEARCH & HEALTH
Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population
JOURNAL OF HUMAN GENETICS
Impact of recent molecular studies on evaluation of ventricular arrhythmias
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
Computational modelling of biological systems: tools and visions
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
Antiarrhythmics - from cell to clinic: past, present, and future
HEART
Suppression of cesium-induced ventricular tachyarrhythmias by atrial natriuretic peptide in rabbits
JOURNAL OF CARDIAC FAILURE
Long QT syndrome: Cellular basis and arrhythmia mechanism in LQT2
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
Spondylometaphyseal dysplasia Sedaghatian type associated with lethal arrhythmia and normal intrauterine growth in three siblings
CLINICAL DYSMORPHOLOGY
Cyclic AMP regulates the HERG K+ channel by dual pathways
CURRENT BIOLOGY
Neurological diseases caused by ion-channel mutations
CURRENT OPINION IN NEUROBIOLOGY
Are some idiopathic epilepsies disorders of ion channels?: A working hypothesis
EPILEPSY RESEARCH
From ionic currents to molecular mechanisms: The structure and function ofvoltage-gated sodium channels
NEURON
Molecular diagnosis and treatment of cardiovascular diseases
CANADIAN JOURNAL OF CARDIOLOGY
The distinct HERG missense mutation L564P causes long QT syndrome in one French Canadian family
CANADIAN JOURNAL OF CARDIOLOGY
Potassium transport: molecular and pathological aspects
M S-MEDECINE SCIENCES
The Long QT Syndromes: Genetic basis and clinical implications
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Homozygosity for a HERG potassium channel mutation causes a severe form oflong-QT syndrome: Identification of an apparent founder mutation in the Finns
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Novel characteristics of a misprocessed mutant HERG channel linked to hereditary long QT syndrome
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3
HUMAN GENETICS
Familial and acquired long QT syndrome and the cardiac rapid delayed rectifier potassium current
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Molecular genetics of arrhythmias - a new paradigm
ZEITSCHRIFT FUR KARDIOLOGIE
Electrophysiological characteristics of antiarrhythmic potential of acrophyllidine, a furoquinoline alkaloid isolated from Acronychia halophylla
DRUG DEVELOPMENT RESEARCH
Do glia have heart? Expression and functional role for ether-a-go-go currents in hippocampal astrocytes
JOURNAL OF NEUROSCIENCE
Molecular biology of arrhythmic syndromes
CURRENT OPINION IN CARDIOLOGY
Current concepts in long QT syndrome
PEDIATRIC CARDIOLOGY