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La ricerca find articoli where soggetti phrase all words 'bone morphogenetic protein' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 1233 riferimenti
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    1. Spinella-Jaegle, S; Roman-Roman, S; Faucheu, C; Dunn, FW; Kawai, S; Gallea, S; Stiot, V; Blanchet, AM; Courtois, B; Baron, R; Rawadi, G
      Opposite effects of bone morphogenetic protein-2 and transforming growth factor-beta 1 on osteoblast differentiation

      BONE
    2. Tamura, S; Kataoka, H; Matsui, Y; Shionoya, Y; Ohno, K; Michi, KI; Takahashi, K; Yamaguchi, A
      The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/carrier complex on bone repair

      BONE
    3. Gallea, S; Lallemand, F; Atfi, A; Rawadi, G; Ramez, V; Spinella-Jaegle, S; Kawai, S; Faucheu, C; Huet, L; Baron, R; Roman-Roman, S
      Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2Cl2 cells

      BONE
    4. Musgrave, DS; Pruchnic, R; Wright, V; Bosch, P; Ghivizzani, SC; Robbins, PD; Huard, J
      The effect of bone morphogenetic protein-2 expression on the early fate ofskeletal muscle-derived cells

      BONE
    5. Schmidmaier, G; Wildemann, B; Bail, H; Lucke, M; Fuchs, T; Stemberger, A; Flyvbjerg, A; Haas, NP; Raschke, M
      Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-beta 1) from a biodegradable poly(D,L-lactide) coating of osteosynthetic implants accelerates fracture healing in rats

      BONE
    6. Horiuchi, H; Saito, N; Kinoshita, T; Wakabayashi, S; Tsutsumimoto, T; Takaoka, K
      Enhancement of bone morphogenetic protein-2-induced new bone formation in mice by the phosphodiesterase inhibitor pentoxifylline

      BONE
    7. Baron, MH
      Molecular regulation of embryonic hematopoiesis and vascular development: A novel pathway

      JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
    8. Peng, HR; Chen, ST; Wergedal, JE; Polo, JM; Yee, JK; Lau, KHW; Baylink, DJ
      Development of an MFG-based retroviral vector system for secretion of highlevels of functionally active human BMP4

      MOLECULAR THERAPY
    9. Moutsatsos, IK; Turgeman, G; Zhou, SH; Kurkalli, BG; Pelled, G; Tzur, L; Kelley, P; Stumm, N; Mi, S; Muller, R; Zilberman, Y; Gazit, D
      Exogenously regulated stem cell-mediated gene therapy for bone regeneration

      MOLECULAR THERAPY
    10. Stainier, DYR
      Zebrafish genetics and vertebrate heart formation

      NATURE REVIEWS GENETICS
    11. De Caestecker, M; Meyrick, B
      Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension

      RESPIRATORY RESEARCH
    12. Vincenti, MP; Brinckerhoff, CE
      Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1 beta

      ARTHRITIS RESEARCH
    13. Hamdy, FC; Thomas, BG
      New therapeutic concepts in prostate cancer

      BJU INTERNATIONAL
    14. Knaus, P; Sebald, W
      Cooperativity of binding epitopes and receptor chains in the BMP/TGF beta superfamily

      BIOLOGICAL CHEMISTRY
    15. Jin, Y; Tipoe, GL; Liong, EC; Lau, TYH; Fung, PCW; Leung, KM
      Overexpression of BMP-2/4,-5 and BMPR-IA associated with malignancy of oral epithelium

      ORAL ONCOLOGY
    16. Takeishi, H; Irie, K; Okuda, K; Ozawa, H; Yajima, T; Ejiri, S
      Molded bone augmentation by a combination of barrier membrane and recombinant human bone morphogenetic protein-2

      ORAL DISEASES
    17. Arihiro, K; Inai, K
      Expression of CD31, Met/hepatocyte growth factor receptor and bone morphogenetic protein in bone metastasis of osteosarcoma

      PATHOLOGY INTERNATIONAL
    18. Turgeman, G; Pittman, DD; Muller, R; Kurkalli, BG; Zhou, SH; Pelled, G; Peyser, A; Zilberman, Y; Moutsatsos, IK; Gazit, D
      Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapy

      JOURNAL OF GENE MEDICINE
    19. Weisser, J; Rahfoth, B; Timmermann, A; Aigner, T; Brauer, R; von der Mark, K
      Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose

      OSTEOARTHRITIS AND CARTILAGE
    20. Vortkamp, A
      Interaction of growth factors regulating chondrocyte differentiation in the developing embryo

      OSTEOARTHRITIS AND CARTILAGE
    21. Mummery, CL
      Transforming growth factor beta and mouse development

      MICROSCOPY RESEARCH AND TECHNIQUE
    22. Bainter, JJ; Boos, A; Kroll, KL
      Neural induction takes a transcriptional twist

      DEVELOPMENTAL DYNAMICS
    23. Flanders, KC; Kim, ES; Roberts, AB
      Immunohistochemical expression of Smads 1-6 in the 15-day gestation mouse embryo: Signaling by BMPs and TGF-beta s

      DEVELOPMENTAL DYNAMICS
    24. Varady, P; Li, JZ; Cunningham, M; Beres, EJ; Das, S; Engh, J; Alden, TD; Pittman, DD; Kerns, KM; Kallmes, DF; Helm, GA
      Morphologic analysis of BMP-9 gene therapy-induced osteogenesis

      HUMAN GENE THERAPY
    25. Shi, W; Zhao, JS; Anderson, KD; Warburton, D
      Gremlin negatively modulates BMP-4 induction of embryonic mouse lung branching morphogenesis

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    26. Martinez, G; Loveland, KL; Clark, AT; Dziadek, M; Bertram, JF
      Expression of bone morphogenetic protein receptors in the developing mousemetanephros

      EXPERIMENTAL NEPHROLOGY
    27. Kiecker, C; Niehrs, C
      The role of prechordal mesendoderm in neural patterning

      CURRENT OPINION IN NEUROBIOLOGY
    28. Standley, HJ; Zorn, AM; Gurdon, JB
      eFGF and its mode of action in the community effect during Xenopus myogenesis

      DEVELOPMENT
    29. Bauer, H; Lele, Z; Rauch, GJ; Geisler, R; Hammerschmidt, M
      The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo

      DEVELOPMENT
    30. Gomez-Skarmeta, JL; de la Calle-Mustienes, E; Modolell, J
      The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4

      DEVELOPMENT
    31. Ahn, K; Mishina, Y; Hanks, MC; Behringer, RR; Crenshaw, EB
      BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb

      DEVELOPMENT
    32. Pizette, S; Abate-Shen, C; Niswander, L
      BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb

      DEVELOPMENT
    33. Dibner, C; Elias, S; Frank, D
      XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos

      DEVELOPMENT
    34. Tremblay, KD; Dunn, NR; Robertson, EJ
      Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

      DEVELOPMENT
    35. Lee, MA; Heasman, J; Whitman, M
      Timing of endogenous activin-like signals and regional specification of the Xenopus embryo

      DEVELOPMENT
    36. Yao, J; Kessler, DS
      Goosecoid promotes head organizer activity by direct repression of Xwnt8 in Spemann's organizer

      DEVELOPMENT
    37. Yamamoto, TS; Takagi, C; Hyodo, AC; Ueno, N
      Suppression of head formation by Xmsx-1 through the inhibition of intracellular nodal signaling

      DEVELOPMENT
    38. Mead, PE; Deconinck, AE; Huber, TL; Orkin, SH; Zon, LI
      Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins

      DEVELOPMENT
    39. Ueno, A; Kitase, Y; Moriyama, K; Inoue, H
      MC3T3-E1-conditioned medium-induced mineralization by clonal rat dental pulp cells

      MATRIX BIOLOGY
    40. Uusitalo, H; Hiltunen, A; Kahari, VM; Aro, H; Vuorio, E; Ahonen, M
      Induction of periosteal callus formation by bone morphogenetic protein-2 employing adenovirus-mediated gene delivery

      MATRIX BIOLOGY
    41. Spivak, JM; Hasharoni, A
      Use of hydroxyapatite in spine surgery

      EUROPEAN SPINE JOURNAL
    42. Mey, J
      Retinoic acid as a regulator of cytokine signaling after nerve injury

      ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
    43. Bragg, AD; Moses, HL; Serra, R
      Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor beta and bone morphogenetic protein 4 on murine embryonic lung development

      MECHANISMS OF DEVELOPMENT
    44. Knochel, S; Dillinger, K; Koster, M; Knochel, W
      Structure and expression of Xenopus tropicalis BMP-2 and BMP-4 genes

      MECHANISMS OF DEVELOPMENT
    45. Patzke, H; Reissmann, E; Stanke, M; Bixby, JL; Ernsberger, U
      BMP growth factors and Phox2 transcription factors can induce synaptotagmin I and neurexin I during sympathetic neuron development

      MECHANISMS OF DEVELOPMENT
    46. Mowbray, C; Hammerschmidt, M; Whitfield, TT
      Expression of BMP signalling pathway members in the developing zebrafish inner ear and lateral line

      MECHANISMS OF DEVELOPMENT
    47. Pathi, S; Pagan-Westphal, S; Baker, DP; Garber, EA; Rayhorn, P; Bumcrot, D; Tabin, CJ; Pepinsky, RB; Williams, KP
      Comparative biological responses to human Sonic, Indian, and Desert hedgehog

      MECHANISMS OF DEVELOPMENT
    48. Gamse, JT; Sive, H
      Early anteroposterior division of the presumptive neurectoderm in Xenopus

      MECHANISMS OF DEVELOPMENT
    49. Kruzynska-Frejtag, A; Machnicki, M; Rogers, R; Markwald, RR; Conway, SJ
      Periostin (an osteoblast-specific factor) is expressed within the embryonic mouse heart during valve formation

      MECHANISMS OF DEVELOPMENT
    50. Colnot, CI; Helms, JA
      A molecular analysis of matrix remodeling and angiogenesis during long bone development

      MECHANISMS OF DEVELOPMENT
    51. Payne, TL; Postlethwait, JH; Yelick, PC
      Functional characterization and genetic mapping of alk8

      MECHANISMS OF DEVELOPMENT
    52. Grotewold, L; Plum, M; Dildrop, R; Peters, T; Ruther, U
      Bambi is coexpressed with Bmp-4 during mouse embryogenesis

      MECHANISMS OF DEVELOPMENT
    53. Kusumi, T; Nishi, T; Tanaka, M; Tsuchida, S; Kudo, H
      A murine osteosarcoma cell line with a potential to develop ossification upon transplantation

      JAPANESE JOURNAL OF CANCER RESEARCH
    54. White, PM; Morrison, SJ; Orimoto, K; Kubu, CJ; Verdi, JM; Anderson, DJ
      Neural crest stem cells undergo cell-intrinsic developmental changes in sensitivity to instructive differentiation signals

      NEURON
    55. Bilodeau, ML; Greulich, JD; Hullinger, RL; Bertolotto, C; Ballotti, R; Andrisani, OM
      BMP-2 stimulates tyrosinase gene expression and melanogenesis in differentiated melanocytes

      PIGMENT CELL RESEARCH
    56. Botchkarev, VA; Botchkareva, NV; Nakamura, M; Huber, O; Funa, K; Lauster, R; Paus, R; Gilchrest, BA
      Noggin is required for induction of the hair follicle growth phase in postnatal skin

      FASEB JOURNAL
    57. Schneider, VA; Mercola, M
      Wnt antagonism initiates cardiogenesis in Xenopus laevis

      GENES & DEVELOPMENT
    58. Marvin, MJ; Di Rocco, G; Gardiner, A; Bush, SM; Lassar, AB
      Inhibition of Wnt activity induces heart formation from posterior mesoderm

      GENES & DEVELOPMENT
    59. Panchision, DM; Pickel, JM; Studer, L; Lee, SH; Turner, PA; Hazel, TG; McKay, RDG
      Sequential actions of BMP receptors control neural precursor cell production and fate

      GENES & DEVELOPMENT
    60. Rossi, JM; Dunn, NR; Hogan, BLM; Zaret, KS
      Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

      GENES & DEVELOPMENT
    61. Kato, Y; Boskey, K; Spevak, L; Dallas, M; Hori, M; Bonewald, LF
      Establishment of an osteoid preosteocyte-like cell MLO-A5 that spontaneously mineralizes in culture

      JOURNAL OF BONE AND MINERAL RESEARCH
    62. Li, HK; Bartold, PM; Young, WG; Xiao, Y; Waters, MJ
      Growth hormone induces bone morphogenetic proteins and bone-related proteins in the developing rat periodontium

      JOURNAL OF BONE AND MINERAL RESEARCH
    63. Yoshimura, Y; Nomura, S; Kawasaki, S; Tsutsumimoto, T; Shimizu, T; Takaoka, K
      Colocalization of noggin and bone morphogenetic protein-4 during fracture healing

      JOURNAL OF BONE AND MINERAL RESEARCH
    64. Tamada, H; Kitazawa, R; Gohji, K; Kitazawa, S
      Epigenetic regulation of human bone morphogenetic protein 6 gene expression in prostate cancer

      JOURNAL OF BONE AND MINERAL RESEARCH
    65. Kawaguchi, J; Kii, I; Sugiyama, Y; Takeshita, S; Kudo, A
      The transition of cadherin expression in osteoblast differentiation from mesenchymal cells: Consistent expression of cadherin-11 in osteoblast lineage

      JOURNAL OF BONE AND MINERAL RESEARCH
    66. Locklin, RM; Riggs, BL; Hicok, KC; Horton, HF; Byrne, MC; Khosla, S
      Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology

      JOURNAL OF BONE AND MINERAL RESEARCH
    67. Nifuji, A; Miura, N; Kato, N; Kellermann, O; Noda, M
      Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells

      JOURNAL OF BONE AND MINERAL RESEARCH
    68. Tamura, Y; Takeuchi, Y; Suzawa, M; Fukumoto, S; Kato, M; Miyazono, K; Fujita, T
      Focal adhesion kinase activity is required for bone morphogenetic protein - Smad1 signaling and osteoblastic differentiation in murine MC3T3-E1 cells

      JOURNAL OF BONE AND MINERAL RESEARCH
    69. Uusitalo, H; Hiltunen, A; Ahonen, M; Gao, TJ; Lefebvre, V; Harley, V; Kahari, VM; Vuorio, E
      Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transferduring murine fracture healing

      JOURNAL OF BONE AND MINERAL RESEARCH
    70. Ikegame, M; Ishibashi, O; Yoshizawa, T; Shimomura, J; Komori, T; Ozawa, H; Kawashima, H
      Tensile stress induces bone morphogenetic protein 4 in preosteoblastic andfibroblastic cells, which later differentiate into osteoblasts leading to osteogenesis in the mouse calvariae in organ culture

      JOURNAL OF BONE AND MINERAL RESEARCH
    71. McCracken, M; Lemons, JE; Zinn, K
      Analysis of Ti-6Al-4V implants placed with fibroblast growth factor 1 in rat tibiae

      INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
    72. Durand, C; Charlemagne, J; Fellah, J
      The origin of hematopoietic stem cells in amphibians

      M S-MEDECINE SCIENCES
    73. Watkins, BA; Li, Y; Seifert, MF
      Nutraceutical fatty acids as biochemical and molecular modulators of skeletal biology

      JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
    74. Xiao, ZS; Liu, SG; Hinson, TK; Quarles, LD
      Characterization of the upstream mouse Cbfa1/Runx2 promoter

      JOURNAL OF CELLULAR BIOCHEMISTRY
    75. Olmsted, EA; Blum, JS; Rill, D; Yotnda, P; Gugala, Z; Lindsey, RW; Davis, AR
      Adenovirus-mediated BMP2 expression in human bone marrow stromal cells

      JOURNAL OF CELLULAR BIOCHEMISTRY
    76. Kitaoka, E; Satomura, K; Hayashi, E; Yamanouchi, K; Tobiume, S; Kume, K; Obinata, M; Nagayama, M
      Establishment and characterization of chondrocyte cell lines from the costal cartilage of SV40 large T antigen transgenic mice

      JOURNAL OF CELLULAR BIOCHEMISTRY
    77. Hanada, K; Solchaga, LA; Caplan, AI; Hering, TM; Goldberg, VM; Yoo, JU; Johnstone, B
      BMP-2 induction and TGF-beta 1 modulation of rat periosteal cell chondrogenesis

      JOURNAL OF CELLULAR BIOCHEMISTRY
    78. Debiais, F; Lemonnier, J; Hay, E; Delannoy, P; Caverzasio, J; Marie, PJ
      Fibroblast growth factor-2 (FGF-2) increases N-cadherin expression throughprotein kinase C and Src-kinase pathways in human calvaria osteoblasts

      JOURNAL OF CELLULAR BIOCHEMISTRY
    79. Prince, M; Banerjee, C; Javed, A; Green, J; Lian, JB; Stein, GS; Bodine, PVN; Komm, BS
      Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markersduring the growth and differentiation of human osteoblasts

      JOURNAL OF CELLULAR BIOCHEMISTRY
    80. Yokota, S; Sonohara, S; Yoshida, M; Murai, M; Shimokawa, S; Fujimoto, R; Fukushima, S; Kokubo, S; Nozaki, K; Takahashi, K; Uchida, T; Yokohama, S; Sonobe, T
      A new recombinant human bone morphogenetic protein-2 carrier for bone regeneration

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    81. Okuda, S; Myoui, A; Nakase, T; Wada, E; Yonenobu, K; Yoshikawa, H
      Ossification of the ligamentum flavum associated with osteoblastoma: a report of three cases

      SKELETAL RADIOLOGY
    82. Piscione, TD; Phan, T; Rosenblum, ND
      BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and-independent pathways

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    83. Minamide, A; Kawakami, M; Hashizume, H; Sakata, R; Tamaki, T
      Evaluation of carriers of bone morphogenetic protein for spinal fusion

      SPINE
    84. Magin, MN; Delling, G
      Improved lumbar vertebral interbody fusion using rhOP-1 - A comparison of autogenous bone graft, bovine hydroxylapatite (Bio-Oss), and BMP-7 (rhOP-1)in sheep

      SPINE
    85. Erulkar, JS; Grauer, JN; Patel, TC; Panjabi, MM
      Flexibility analysis of posterolateral fusions in a New Zealand white rabbit model

      SPINE
    86. Li, HS; Zou, XN; Bunger, C
      Gene therapy and spinal disorders

      INTERNATIONAL ORTHOPAEDICS
    87. Zwijsen, A; van Grunsven, LA; Bosman, EA; Collart, C; Nelles, L; Umans, L; Van de Putte, T; Wuytens, G; Huylebroeck, D; Verschueren, K
      Transforming growth factor beta signalling in vitro and in vivo: activin ligand-receptor interaction, Smad5 in vasculogenesis, and repression of target genes by the delta EF1/ZEB-related SIP1 in the vertebrate embryo

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    88. King, GN; Hughes, FJ
      Bone morphogenetic protein-2 stimulates cell recruitment and cementogenesis during early wound healing

      JOURNAL OF CLINICAL PERIODONTOLOGY
    89. Talwar, R; Di Silvio, L; Hughes, FJ; King, GN
      Effects of carrier release kinetics on bone morphogenetic protein-2-induced periodontal regeneration in vivo

      JOURNAL OF CLINICAL PERIODONTOLOGY
    90. Abdelwahid, E; Rice, D; Pelliniemi, LJ; Jokinen, E
      Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart

      CELL AND TISSUE RESEARCH
    91. Houldsworth, J; Reuter, VE; Bosl, GJ; Chaganti, RSK
      ID gene expression varies with lineage during differentiation of pluripotential male germ cell tumor cell lines

      CELL AND TISSUE RESEARCH
    92. Ishizuya-Oka, A; Ueda, S; Amano, T; Shimizu, K; Suzuki, K; Ueno, N; Yoshizato, K
      Thyroid-hormone-dependent and fibroblast-specific expression of BMP-4 correlates with adult epithelial development during amphibian intestinal remodeling

      CELL AND TISSUE RESEARCH
    93. Hannouche, D; Petite, H; Sedel, L
      Current trends in the enhancement of fracture healing

      JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
    94. Mayr-Wohlfart, U; Kessler, S; Puhl, W; Gunther, KP; Knochel, W
      BMP-4 of Xenopus laevis stimulates differentiation of human primary osteoblast-like cells

      JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
    95. Baron, MH
      Induction of embryonic hematopoietic and endothelial stem/progenitor cellsby hedgehog-mediated signals

      DIFFERENTIATION
    96. Kohyama, J; Abe, H; Shimazaki, T; Koizumi, A; Nakashima, K; Gojo, S; Taga, T; Okano, H; Hata, J; Umezawa, A
      Brain from bone: Efficient "meta-differentiation" of marrow stroma-derivedmature osteoblasts to neurons with Noggin or a demethylating agent

      DIFFERENTIATION
    97. Asakura, A; Komaki, M; Rudnicki, MA
      Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation

      DIFFERENTIATION
    98. Carlberg, AL; Pucci, B; Rallapalli, R; Tuan, RS; Hall, DJ
      Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of BMP-2

      DIFFERENTIATION
    99. Tateyama, S; Uchida, K; Hidaka, T; Hirao, M; Yamaguchi, R
      Expression of bone morphogenetic protein-6 (BMP-6) in myoepithelial cells in canine mammary gland tumors

      VETERINARY PATHOLOGY
    100. Nicoll, SB; Wedrychowska, A; Smith, NR; Bhatnagar, RS
      Modulation of proteoglycan and collagen profiles in human dermal fibroblasts by high density micromass culture and treatment with lactic acid suggests change to a chondrogenic phenotype

      CONNECTIVE TISSUE RESEARCH


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Documento generato il 07/08/20 alle ore 07:20:36