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    1. Giavazzi, R; Taraboletti, G
      Preclinical development of metalloproteasis inhibitors in cancer therapy

      CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
    2. Ziswiler, R; Daniel, C; Franz, E; Marti, HP
      Renal matrix metalloproteinase activity is unaffected by experimental ischemia-reperfusion injury and matrix metalloproteinase inhibition does not alter outcome of renal function

      EXPERIMENTAL NEPHROLOGY
    3. Glasspool, RM; Twelves, CJ
      Matrix metalloproteinase inhibitors: past lessons and future prospects in breast cancer

      BREAST
    4. Pross, M; Lippert, H; Mantke, R; Kruger, S; Gunther, T; Marusch, F; Halangk, W; Schulz, HU
      A proteinase inhibitor decreases tumor growth in a laparoscopic rat model

      SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES
    5. Ohta, M; Konno, H; Tanaka, T; Baba, M; Kamiya, K; Oba, K; Kaneko, T; Syouji, T; Igarashi, A; Nakamura, S
      Effect of combination therapy with matrix metalloproteinase inhibitor MMI-166 and mitomycin C on the growth and liver metastasis of human colon cancer

      JAPANESE JOURNAL OF CANCER RESEARCH
    6. Alves, F; Borchers, U; Padge, B; Augustin, H; Nebendahl, K; Kloppel, G; Tietze, LF
      Inhibitory effect of a matrix metalloproteinase inhibitor on growth and spread of human pancreatic ductal adenocarcinoma evaluated in an orthotopic severe combined immunodeficient (SCID) mouse model

      CANCER LETTERS
    7. Verdolini, R; Amerio, P; Goteri, G; Bugatti, L; Lucarini, G; Mannello, B; Filosa, G; Offidani, A; Brancorsini, D; Biagini, G; Giangiacomi, M
      Cutaneous carcinomas and preinvasive neoplastic lesions. Role of MMP-2 andMMP-9 metalloproteinases in neoplastic invasion and their relationship with proliferative activity and p53 expression

      JOURNAL OF CUTANEOUS PATHOLOGY
    8. Pang, S; Chubb, AJ; Schwager, SLU; Ehlers, MRW; Sturrock, ED; Hooper, NM
      Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding

      BIOCHEMICAL JOURNAL
    9. Holst-Hansen, C; Low, JA; Stephens, RW; Johnson, MD; Carmeliet, P; Frandsen, TL; Brunner, N; Dickson, RB
      Increased stromal expression of murine urokinase plasminogen activator in a human breast cancer xenograft model following treatment with the matrix metalloprotease inhibitor, batimastat

      BREAST CANCER RESEARCH AND TREATMENT
    10. Mungall, BA; Pollitt, CC
      In situ zymography: topographical considerations

      JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS
    11. Jantova, S; Urbancikova, M; Maliar, T; Mikulasova, M; Rauko, P; Cipak, L; Kubikova, J; Stankovsky, S; Spirkova, K
      Biological activity of some 4-anilinoquinazolines: cytotoxic, genotoxic and antiprotease effects, induction of necrosis and changes of actin cytoskeleton

      NEOPLASMA
    12. Corbel, M; Caulet-Maugendre, S; Germain, N; Molet, S; Lagente, V; Boichot, E
      Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat

      JOURNAL OF PATHOLOGY
    13. Lee, PPH; Hwang, JJ; Mead, L; Ip, MM
      Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development

      JOURNAL OF CELLULAR PHYSIOLOGY
    14. Matsushita, A; Onda, M; Uchida, E; Maekawa, R; Yoshioka, T
      Antitumor effect of a new selective matrix metalloproteinase inhibitor, MMI-166, on experimental pancreatic cancer

      INTERNATIONAL JOURNAL OF CANCER
    15. Duivenvoorden, WCM; Hirte, HW; Singh, G
      Quantification of matrix metalloproteinase activity in plasma of patients enrolled in a BAY 12-9566 phase I study

      INTERNATIONAL JOURNAL OF CANCER
    16. Corbel, M; Lanchou, JM; Germain, N; Malledant, Y; Boichot, E; Lagente, V
      Modulation of airway remodeling-associated mediators by the antifibrotic compound, pirfenidone, and the matrix metalloproteinase inhibitor, batimastat, during acute lung injury in mice

      EUROPEAN JOURNAL OF PHARMACOLOGY
    17. Di Sebastiano, P; di Mola, FF; Artese, L; Rossi, C; Mascetta, G; Pernthaler, H; Innocenti, P
      Beneficial effects of Batimastat (BB-94), a matrix metalloproteinase inhibitor, in rat experimental colitis

      DIGESTION
    18. Aslam, N; Marino, CR
      Malignant ascites - New concepts in pathophysiology, diagnosis, and management

      ARCHIVES OF INTERNAL MEDICINE
    19. Johnston, MR; Mullen, JBM; Pagura, ME; Howard, RB
      Validation of an orthotopic model of human lung cancer with regional and systemic metastases

      ANNALS OF THORACIC SURGERY
    20. Duffy, MJ; Maguire, TM; Hill, A; McDermott, E; O'Higgins, N
      Metalloproteinases: role in breast carcinogenesis, invasion and metastasis

      BREAST CANCER RESEARCH
    21. Thomas, AL; Steward, WP
      Marimastat: the clinical development of a matrix metalloproteinase inhibitor

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    22. Hernandez-Pando, R; Orozco, H; Arriaga, K; Pavon, L; Rook, G
      Treatment with BB-94, a broad spectrum inhibitor of zinc-dependent metalloproteinases, causes deviation of the cytokine profile towards Type-2 in experimental pulmonary tuberculosis in Balb/c mice

      INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
    23. Nemunaitis, J; Cox, J; Hays, S; Meyer, W; Kebart, R; Ognoskie, N; Courtney, A; Yu, Y; Rasmussen, H; Tong, A
      Prognostic role of K-ras in patients with progressive colon cancer who received treatment with Marimastat (BB2516)

      CANCER INVESTIGATION
    24. Lacroix, M; Marie, PJ; Body, JJ
      Protein production by osteoblasts: modulation by breast cancer cell-derived factors

      BREAST CANCER RESEARCH AND TREATMENT
    25. Sporer, B; Koedel, U; Paul, R; Kohleisen, B; Erfle, V; Fontana, A; Pfister, HW
      Human immunodeficiency virus type-1 Nef protein induces blood-brain barrier disruption in the rat: role of matrix metalloproteinase-9

      JOURNAL OF NEUROIMMUNOLOGY
    26. Lee, PPH; Hwang, JJ; Murphy, G; Ip, MM
      Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells

      ENDOCRINOLOGY
    27. Heath, EI; Grochow, LB
      Clinical potential of matrix metalloprotease inhibitors in cancer therapy

      DRUGS
    28. Song, WM; Jackson, K; McGuire, PG
      Degradation of type IV collagen by matrix metalloproteinases is an important step in the epithelial-mesenchymal transformation of the endocardial cushions

      DEVELOPMENTAL BIOLOGY
    29. Haq, M; Shafii, A; Zervos, EE; Rosemurgy, AS
      Addition of matrix metalloproteinase inhibition to conventional cytotoxic therapy reduces tumor implantation and prolongs survival in a murine model of human pancreatic cancer

      CANCER RESEARCH
    30. Scott, KA; Holdsworth, H; Balkwill, FR; Dias, S
      Exploiting changes in the tumour microenvironment with sequential cytokineand matrix metalloprotease inhibitor treatment in a murine breast cancer model

      BRITISH JOURNAL OF CANCER
    31. Escalante, T; Franceschi, A; Rucavado, A; Gutierrez, JM
      Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper

      BIOCHEMICAL PHARMACOLOGY
    32. Wang, H; Keiser, JA
      Hepatocyte growth factor enhances MMP activity in human endothelial cells

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    33. Jimenez, RE; Hartwig, W; Antoniu, BA; Compton, CC; Warshaw, AL; Fernandez-del Castillo, C
      Effect of matrix metalloproteinase inhibition on pancreatic cancer invasion and metastasis - An additive strategy for cancer control

      ANNALS OF SURGERY
    34. Lana, SE; Ogilvie, GK; Hansen, RA; Powers, BE; Dernell, WS; Withrow, SJ
      Identification In of matrix metalloproteinases in canine neoplastic tissue

      AMERICAN JOURNAL OF VETERINARY RESEARCH
    35. Del Bigio, MR; Seyoum, G
      Effect of matrix metalloproteinase inhibitors on rat embryo development invitro

      CELLS TISSUES ORGANS
    36. Price, A; Shi, QA; Morris, D; Wilcox, ME; Brasher, PMA; Rewcastle, NB; Shalinsky, D; Zou, H; Appelt, K; Johnston, RN; Yong, VW; Edwards, D; Forsyth, P
      Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340

      CLINICAL CANCER RESEARCH
    37. Erba, E; Ronzoni, S; Bassano, L; Giavazzi, R; D'Incalci, M
      The metalloproteinase inhibitor batimastat (BB-94) causes cell cycle phaseperturbations in ovarian cancer cells

      ANNALS OF ONCOLOGY
    38. Kido, A; Tsutsumi, M; Iki, K; Motoyama, M; Takahama, M; Tsujiuchi, T; Morishita, T; Tatsumi, K; Tamai, S; Konishi, Y
      Inhibition of spontaneous rat osteosarcoma lung metastasis by 3S-[4-(N-hydroxyamino)-2R-isobutylsuccinyl]amino-1-methoxy-3,4-dihydrocarbostyril, a novel matrix metalloproteinase inhibitor

      JAPANESE JOURNAL OF CANCER RESEARCH
    39. Brown, PD
      Clinical studies with matrix metalloproteinase inhibitors

      APMIS
    40. Bigatel, DA; Elmore, JR; Carey, DJ; Cizmeci-Smith, G; Franklin, DP; Youkey, JR
      The matrix metalloproteinase inhibitor BB-94 limits expansion of experimental abdominal aortic aneurysms

      JOURNAL OF VASCULAR SURGERY
    41. Aparicio, T; Lehy, T
      Matrix metalloproteinases in digestive pathology.

      GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
    42. Steward, WP
      Marimastat (BB2516): Current status of development

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    43. Wylie, S; MacDonald, IC; Varghese, HJ; Schmidt, EE; Morris, VL; Groom, AC; Chambers, AF
      The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis inliver metastases of B16F1 melanoma cells

      CLINICAL & EXPERIMENTAL METASTASIS
    44. Rao, VH; Singh, RK; Finnell, RH; Dave, BJ; Beuhler, BA; Sanger, WG; Schaefer, GB
      Matrix metalloproteinases and their inhibitors in tumor invasion and metastasis

      PROCEEDINGS OF THE INDIAN ACADEMY OF SCIENCES-CHEMICAL SCIENCES
    45. Della Porta, P; Soeltl, R; Krell, HW; Collins, K; O'Donoghue, M; Schmitt, M; Kruger, A
      Combined treatment with serine protease inhibitor aprotinin and matrix metalloproteinase inhibitor batimastat (BB-94) does not prevent invasion of human esophageal and ovarian carcinoma cells in vivo

      ANTICANCER RESEARCH
    46. Aparicio, T; Kermorgant, S; Dessirier, V; Lewin, MJM; Lehy, T
      Matrix metalloproteinase inhibition prevents colon cancer peritoneal carcinomatosis development and prolongs survival in rats

      CARCINOGENESIS
    47. Krug, LM; Grant, SC; Miller, VA; Ng, KK; Kris, MG
      Strategies to eradicate minimal residual disease in small cell lung cancer: High-dose chemotherapy with autologous bone marrow transplantation, matrix metalloproteinase inhibitors, and BEC2 plus BCG vaccination

      SEMINARS IN ONCOLOGY
    48. Tonn, JC; Kerkau, S; Hanke, A; Bouterfa, H; Mueller, JG; Wagner, S; Vince, GH; Roosen, K
      Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro

      INTERNATIONAL JOURNAL OF CANCER
    49. Griffioen, AW; Damen, CA; Mayo, KH; Barendsz-Janson, AF; Martinotti, S; Blijham, GH; Groenewegen, G
      Angiogenesis inhibitors overcome tumor induced endothelial cell anergy

      INTERNATIONAL JOURNAL OF CANCER
    50. Makela, M; Larjava, H; Pirila, E; Maisi, P; Salo, T; Sorsa, T; Uitto, VJ
      Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes

      EXPERIMENTAL CELL RESEARCH
    51. Watson, SA; Morris, TM; Collins, HM; Bawden, LJ; Hawkins, K; Bone, EA
      Inhibition of tumour growth by marimastat in a human xenograft model of gastric cancer: relationship with levels of circulating CEA

      BRITISH JOURNAL OF CANCER
    52. Baker, AH; George, SJ; Zaltsman, AB; Murphy, G; Newby, AC
      Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3

      BRITISH JOURNAL OF CANCER
    53. Das, A; McLamore, A; Song, WM; McGuire, PG
      Retinal neovascularization is suppressed with a matrix metalloproteinase inhibitor

      ARCHIVES OF OPHTHALMOLOGY
    54. NEMUNAITIS J; POOLE C; PRIMROSE J; ROSEMURGY A; MALFETANO J; BROWN P; BERRINGTON A; CORNISH A; LYNCH K; RASMUSSEN H; KERR D; COX D; MILLAR A
      COMBINED ANALYSIS OF STUDIES OF THE EFFECTS OF THE MATRIX METALLOPROTEINASE INHIBITOR MARIMASTAT ON SERUM TUMOR-MARKERS IN ADVANCED CANCER - SELECTION OF A BIOLOGICALLY-ACTIVE AND TOLERABLE DOSE FOR LONGER-TERM STUDIES

      Clinical cancer research
    55. NEMUNAITIS J; POOLE C; PRIMROSE J; ROSEMURGY A; MALFETANO J; BROWN P; BERRINGTON A; CORNISH A; LYNCH K; RASMUSSEN H; KERR D; COX D; MILLAR A
      COMBINED ANALYSIS OF STUDIES OF THE EFFECTS OF THE MATRIX METALLOPROTEINASE INHIBITOR MARIMASTAT ON SERUM TUMOR-MARKERS IN ADVANCED CANCER - SELECTION OF A BIOLOGICALLY-ACTIVE AND TOLERABLE DOSE FOR LONGER-TERM STUDIES

      Clinical cancer research
    56. EPPS DE; POORMAN RA; PETZOLD GL; STUCHLY CW; LABORDE AL; VANDRIE JH
      THE CONSTITUENT TRYPTOPHANS AND BISANS AS FLUORESCENT-PROBES OF THE ACTIVE-SITE AND OF A SECONDARY BINDING-SITE OF STROMELYSIN-1 (MMP3)

      Journal of protein chemistry
    57. KNOX JD; BRETTON L; LYNCH T; BOWDEN GT; NAGLE RB
      SYNTHETIC MATRIX METALLOPROTEINASE INHIBITOR, BB-94, INHIBITS THE INVASION OF NEOPLASTIC HUMAN PROSTATE CELLS IN A MOUSE MODEL

      The Prostate
    58. Kelly, T; Yan, Y; Osborne, RL; Athota, AB; Rozypal, TL; Colclasure, JC; Chu, WS
      Proteolysis of extracellular matrix by invadopodia facilitates human breast cancer cell invasion and is mediated by matrix metalloproteinases

      CLINICAL & EXPERIMENTAL METASTASIS
    59. Desoize, B; Gimonet, D; Jardiller, JC
      Cell culture as spheroids: An approach to multicellular resistance

      ANTICANCER RESEARCH
    60. BU W; TANG ZY; SUN FX; YE SL; LIU KD; XUE Q; CHEN J; GAO DM
      EFFECTS OF MATRIX METALLOPROTEINASE INHIBITOR BB-94 ON LIVER-CANCER GROWTH AND METASTASIS IN A PATIENT-LIKE ORTHOTOPIC MODEL LCI-D20

      Hepato-gastroenterology
    61. Brown, PD
      Matrix metalloproteinase inhibitors

      BREAST CANCER RESEARCH AND TREATMENT
    62. ZETTER BR
      ANGIOGENESIS AND TUMOR-METASTASIS

      Annual review of medicine
    63. MURRAY GI; DUNCAN ME; ONEIL P; MCKAY JA; MELVIN WT; FOTHERGILL JE
      MATRIX METALLOPROTEINASE-1 IS ASSOCIATED WITH POOR-PROGNOSIS IN ESOPHAGEAL CANCER

      Journal of pathology
    64. GRESS TM; MENKE A; BACHEM M; MULLERPILLASCH F; ELLENRIEDER V; WEIDENBACH H; WAGNER M; ADLER G
      ROLE OF EXTRACELLULAR-MATRIX IN PANCREATIC DISEASES

      Digestion
    65. LOMBARD MA; WALLACE TL; KUBICEK MF; PETZOLD GL; MITCHELL MA; HENDGES SK; WILKS JW
      SYNTHETIC MATRIX METALLOPROTEINASE INHIBITORS AND TISSUE INHIBITOR OFMETALLOPROTEINASE (TIMP)-2, BUT NOT TIMP-1, INHIBIT SHEDDING OF TUMOR-NECROSIS-FACTOR-ALPHA RECEPTORS IN A HUMAN COLON ADENOCARCINOMA (COLO205) CELL-LINE

      Cancer research
    66. KOSHIBA T; HOSOTANI R; WADA M; MIYAMOTO Y; FUJIMOTO K; LEE JU; DOI R; ARII S; IMAMURA M
      INVOLVEMENT OF MATRIX METALLOPROTEINASE-2 ACTIVITY IN INVASION AND METASTASIS OF PANCREATIC-CARCINOMA

      Cancer
    67. WATSON SA; TIERNEY G
      MATRIX METALLOPROTEINASE INHIBITORS - A REVIEW

      Biodrugs
    68. YU AE; HEWITT RE; CONNOR EW; STETLERSTEVENSON WG
      MATRIX METALLOPROTEINASES - NOVEL TARGETS FOR DIRECTED CANCER-THERAPY

      Drugs & aging
    69. SKELLY MM; TROY A; DUFFY MJ; MULCAHY HE; DUGGAN C; CONNELL TG; ODONOGHUE DP; SHEAHAN K
      UROKINASE-TYPE PLASMINOGEN-ACTIVATOR IN COLORECTAL-CANCER - RELATIONSHIP WITH CLINICOPATHOLOGICAL FEATURES AND PATIENT OUTCOME

      Clinical cancer research
    70. BURKE F; EAST N; UPTON C; PATEL K; BALKWILL FR
      INTERFERON-GAMMA INDUCES CELL-CYCLE ARREST AND APOPTOSIS IN A MODEL OF OVARIAN-CANCER - ENHANCEMENT OF EFFECT BY BATIMASTAT

      European journal of cancer
    71. SANTOS O; MCDERMOTT CD; DANIELS RG; APPELT K
      RODENT PHARMACOKINETIC AND ANTITUMOR EFFICACY STUDIES WITH A SERIES OF SYNTHETIC INHIBITORS OF MATRIX METALLOPROTEINASES

      Clinical & experimental metastasis
    72. DENIS LJ; VERWEIJ J
      MATRIX METALLOPROTEINASE INHIBITORS - PRESENT ACHIEVEMENTS AND FUTURE-PROSPECTS

      Investigational new drugs
    73. RASMUSSEN HS; MCCANN PP
      MATRIX METALLOPROTEINASE INHIBITION AS A NOVEL ANTICANCER STRATEGY - A REVIEW WITH SPECIAL FOCUS ON BATIMASTAT AND MARIMASTAT

      Pharmacology & therapeutics
    74. JACKSON RC
      CONTRIBUTIONS OF PROTEIN STRUCTURE-BASED DRUG DESIGN TO CANCER-CHEMOTHERAPY

      Seminars in oncology
    75. ZERVOS EE; NORMAN JG; GOWER WR; FRANZ MG; ROSEMURGY AS
      MATRIX METALLOPROTEINASE INHIBITION ATTENUATES HUMAN PANCREATIC-CANCER GROWTH IN-VITRO AND DECREASES MORTALITY AND TUMORIGENESIS IN-VIVO

      The Journal of surgical research
    76. CHRISTIE G; BARTON A; BOLOGNESE B; BUCKLE DR; COOK RM; HANSBURY MJ; HARPER GP; MARSHALL LA; MCCORD ME; MOULDER K; MURDOCK PR; SEAL SM; SPACKMAN VM; WESTON BJ; MAYER RJ
      IGE SECRETION IS ATTENUATED BY AN INHIBITOR OF PROTEOLYTIC PROCESSINGOF CD23 (FC-EPSILON-RII)

      European Journal of Immunology
    77. EVANS JD; GHANEH P; KAWESHA A; NEOPTOLEMOS JP
      ROLE OF MATRIX METALLOPROTEINASES AND THEIR INHIBITORS IN PANCREATIC-CANCER

      Digestion
    78. VOEST EE
      INHIBITORS OF ANGIOGENESIS IN A CLINICAL PERSPECTIVE

      Anti-cancer drugs
    79. ROTH BJ
      NEW THERAPEUTIC AGENTS FOR HORMONE-REFRACTORY PROSTATE-CANCER

      Seminars in oncology
    80. WATSON SA; MORRIS TM; PARSONS SL; STEELE RJC; BROWN PD
      THERAPEUTIC EFFECT OF THE MATRIX METALLOPROTEINASE INHIBITOR, BATIMASTAT, IN A HUMAN COLORECTAL-CANCER ASCITES MODEL

      British Journal of Cancer


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Documento generato il 25/05/20 alle ore 04:39:50