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1. Takenaka, K; Yasuda, S; Miyazaki, S; Kurita, T; Sutani, Y; Morii, I; Daikoku, S; Kamakura, S; Nonogi, H
   Initial experience with nifekalant hydrochloride (MS-551), a novel class III antiarrhythmic agent, in patients with acute extensive infarction and severe ventricular dysfunction
   JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
   
   K. Takenaka et al., "Initial experience with nifekalant hydrochloride (MS-551), a novel class III antiarrhythmic agent, in patients with acute extensive infarction and severe ventricular dysfunction", JPN CIRC J, 65(1), 2001, pp. 60-62
2. Lu, ZB; Kamiya, K; Opthof, T; Yasui, K; Kodama, I
   Density and kinetics of I-Kr and I-Ks in guinea pig and rabbit ventricularmyocytes explain different efficacy of I-Ks blockade at high heart rate inguinea pig and rabbit - Implications for arrhythmogenesis in humans
   CIRCULATION
   
   Z.B. Lu et al., "Density and kinetics of I-Kr and I-Ks in guinea pig and rabbit ventricularmyocytes explain different efficacy of I-Ks blockade at high heart rate inguinea pig and rabbit - Implications for arrhythmogenesis in humans", CIRCULATION, 104(8), 2001, pp. 951-956
3. Pedersen, OD; Bagger, H; Keller, N; Marchant, B; Kober, L; Torp-Pedersen, C
   Efficacy of dofetilide in the treatment of atrial fibrillation-flutter in patients with reduced left ventricular function - A Danish Investigations of Arrhythmia and Mortality ON Dofetilide (DIAMOND) substudy
   CIRCULATION
   
   O.D. Pedersen et al., "Efficacy of dofetilide in the treatment of atrial fibrillation-flutter in patients with reduced left ventricular function - A Danish Investigations of Arrhythmia and Mortality ON Dofetilide (DIAMOND) substudy", CIRCULATION, 104(3), 2001, pp. 292-296
4. van Opstal, JM; Schoenmakers, M; Verduyn, SC; de Groot, SHM; Leunissen, JDM; van der Hulst, FF; Molenschot, MMC; Wellens, HJJ; Vos, MA
   Chronic amiodarone evokes no Torsade de Pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome
   CIRCULATION
   
   J.M. van Opstal et al., "Chronic amiodarone evokes no Torsade de Pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome", CIRCULATION, 104(22), 2001, pp. 2722-2727
5. Han, W; Chartier, D; Li, DS; Nattel, S
   Ionic remodeling of cardiac Purkinje cells by congestive heart failure
   CIRCULATION
   
   W. Han et al., "Ionic remodeling of cardiac Purkinje cells by congestive heart failure", CIRCULATION, 104(17), 2001, pp. 2095-2100
6. Glatter, KA; Dorostkar, PC; Yang, YF; Lee, RJ; Van Hare, GF; Keung, E; Modin, G; Scheinman, MM
   Electrophysiological effects of ibutilide in patients with accessory pathways
   CIRCULATION
   
   K.A. Glatter et al., "Electrophysiological effects of ibutilide in patients with accessory pathways", CIRCULATION, 104(16), 2001, pp. 1933-1939
7. Simon, T; Mary-Krause, M; Funck-Brentano, C; Jaillon, P
   Sex differences in the prognosis of congestive heart failure - Results from The Cardiac Insufficiency Bisoprolol Study (CIBIS II)
   CIRCULATION
   
   T. Simon et al., "Sex differences in the prognosis of congestive heart failure - Results from The Cardiac Insufficiency Bisoprolol Study (CIBIS II)", CIRCULATION, 103(3), 2001, pp. 375-380
8. Hondeghem, LM; Carlsson, L; Duker, G
   Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic
   CIRCULATION
   
   L.M. Hondeghem et al., "Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic", CIRCULATION, 103(15), 2001, pp. 2004-2013
9. Brendorp, B; Elming, H; Jun, L; Kober, L; Malik, M; Jensen, GB; Torp-Pedersen, C
   QTc interval as a guide to select those patients with congestive heart failure and reduced left ventricular systolic function who will benefit from antiarrhythmic treatment with dofetilide
   CIRCULATION
   
   B. Brendorp et al., "QTc interval as a guide to select those patients with congestive heart failure and reduced left ventricular systolic function who will benefit from antiarrhythmic treatment with dofetilide", CIRCULATION, 103(10), 2001, pp. 1422-1427
10. Greene, M; Newman, D; Geist, M; Paquette, M; Heng, D; Dorian, P
    Is electrical storm in ICD patients the sign of a dying heart? Outcome of patients with clusters of ventricular tachyarrhythmias
    EUROPACE
    
    M. Greene et al., "Is electrical storm in ICD patients the sign of a dying heart? Outcome of patients with clusters of ventricular tachyarrhythmias", EUROPACE, 2(3), 2000, pp. 263-269
11. Wyndham, CRC
    Atrial fibrillation - The most common arrhythmia
    TEXAS HEART INSTITUTE JOURNAL
    
    C.R.C. Wyndham, "Atrial fibrillation - The most common arrhythmia", TEX HEART I, 27(3), 2000, pp. 257-267
12. Geelen, P; O'Hara, GE; Plante, S; Philippon, F; Gilbert, M; Turgeon, J
    Ischemia-induced action potential shortening is blunted by d-sotalol in a pig model of reversible myocardial ischemia
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
    
    P. Geelen et al., "Ischemia-induced action potential shortening is blunted by d-sotalol in a pig model of reversible myocardial ischemia", J CARDIO PH, 35(4), 2000, pp. 638-645
13. Chaudhry, GM; Haffajee, CI
    Antiarrhythmic agents and proarrhythmia
    CRITICAL CARE MEDICINE
    
    G.M. Chaudhry e C.I. Haffajee, "Antiarrhythmic agents and proarrhythmia", CRIT CARE M, 28(10), 2000, pp. N158-N164
14. Abriel, H; Wehrens, XHT; Benhorin, J; Kerem, B; Kass, RS
    Molecular pharmacology of the sodium channel mutation D1790G linked to thelong-QT syndrome
    CIRCULATION
    
    H. Abriel et al., "Molecular pharmacology of the sodium channel mutation D1790G linked to thelong-QT syndrome", CIRCULATION, 102(8), 2000, pp. 921-925
15. Nademanee, K; Taylor, R; Bailey, WE; Rieders, DE; Kosar, EM
    Treating electrical storm - Sympathetic blockade versus advanced cardiac life support-guided therapy
    CIRCULATION
    
    K. Nademanee et al., "Treating electrical storm - Sympathetic blockade versus advanced cardiac life support-guided therapy", CIRCULATION, 102(7), 2000, pp. 742-747
16. Kuck, KH; Cappato, R; Siebels, J; Ruppel, R
    Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest - The Cardiac Arrest Study Hamburg (CASH)
    CIRCULATION
    
    K.H. Kuck et al., "Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest - The Cardiac Arrest Study Hamburg (CASH)", CIRCULATION, 102(7), 2000, pp. 748-754
17. Mounsey, JP; DiMarco, JP
    Dofetilide
    CIRCULATION
    
    J.P. Mounsey e J.P. DiMarco, "Dofetilide", CIRCULATION, 102(21), 2000, pp. 2665-2670
18. Singh, S; Zoble, RG; Yellen, L; Brodsky, MA; Feld, GK; Berk, M; Billing, CB
    Efficacy and safety of oral dofetilide in converting to and maintaining sinus rhythm in patients with chronic atrial fibrillation or atrial flutter -The Symptomatic Atrial Fibrillation Investigative Research on Dofetilide (SAFIRE-D) study
    CIRCULATION
    
    S. Singh et al., "Efficacy and safety of oral dofetilide in converting to and maintaining sinus rhythm in patients with chronic atrial fibrillation or atrial flutter -The Symptomatic Atrial Fibrillation Investigative Research on Dofetilide (SAFIRE-D) study", CIRCULATION, 102(19), 2000, pp. 2385-2390
19. Cabo, C; Schmitt, H; Wit, AL
    New mechanism of antiarrhythmic drug action - Increasing L-type calcium current prevents reentrant ventricular tachycardia in the infarcted canine heart
    CIRCULATION
    
    C. Cabo et al., "New mechanism of antiarrhythmic drug action - Increasing L-type calcium current prevents reentrant ventricular tachycardia in the infarcted canine heart", CIRCULATION, 102(19), 2000, pp. 2417-2425
20. Brugada, R; Brugada, J; Antzelevitch, C; Kirsch, GE; Potenza, D; Towbin, JA; Brugada, P
    Sodium channel blockers identify risk for sudden death in patients with ST-Segment elevation and right bundle branch block but structurally normal hearts
    CIRCULATION
    
    R. Brugada et al., "Sodium channel blockers identify risk for sudden death in patients with ST-Segment elevation and right bundle branch block but structurally normal hearts", CIRCULATION, 101(5), 2000, pp. 510-515
21. Rouet, R; Picard, S; Libersa, C; Ghadanfar, M; Alabaster, C; Gerard, JL
    Electrophysiological effects of dofetilide in an in vitro model of "borderzone" between normal and ischemic/reperfused myocardium
    CIRCULATION
    
    R. Rouet et al., "Electrophysiological effects of dofetilide in an in vitro model of "borderzone" between normal and ischemic/reperfused myocardium", CIRCULATION, 101(1), 2000, pp. 86-93
22. Galante, A; Pietroiusti, A; Cavazzini, C; Magrini, A; Bergamaschi, A; Sciarra, L; Chartouni, G; Legramante, JM; Carta, S
    Incidence and risk factors associated with cardiac arrhythmias during rehabilitation after coronary artery bypass surgery
    ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
    
    A. Galante et al., "Incidence and risk factors associated with cardiac arrhythmias during rehabilitation after coronary artery bypass surgery", ARCH PHYS M, 81(7), 2000, pp. 947-952
23. O'Callaghan, PA; Camm, AJ
    Treatment of arrhythmias in heart failure
    EUROPEAN JOURNAL OF HEART FAILURE
    
    P.A. O'Callaghan e A.J. Camm, "Treatment of arrhythmias in heart failure", EUR J HE FA, 1(2), 1999, pp. 133-137
24. Friedman, HS; Rodney, E; Sinha, B; Sharafkhaneh, A; Watanasuwan, N; Win, M; Mallipeddi, D; Sinha, A; Hussain, A; Dai, CP
    Verapamil prolongs atrial fibrillation by evoking an intense sympathetic neurohumoral effect
    JOURNAL OF INVESTIGATIVE MEDICINE
    
    H.S. Friedman et al., "Verapamil prolongs atrial fibrillation by evoking an intense sympathetic neurohumoral effect", J INVES MED, 47(6), 1999, pp. 293-303
25. Davis, DR; Beatch, GN; Dickenson, DR; Tang, ASL
    Dofetilide enhances shock-induced extension of refractoriness and lowers defibrillation threshold
    CANADIAN JOURNAL OF CARDIOLOGY
    
    D.R. Davis et al., "Dofetilide enhances shock-induced extension of refractoriness and lowers defibrillation threshold", CAN J CARD, 15(2), 1999, pp. 193-200
26. Alings, M; Wilde, A
    "Brugada" syndrome - Clinical data and suggested pathophysiological mechanism
    CIRCULATION
    
    M. Alings e A. Wilde, ""Brugada" syndrome - Clinical data and suggested pathophysiological mechanism", CIRCULATION, 99(5), 1999, pp. 666-673
27. Fromm, MF; Kim, RB; Stein, CM; Wilkinson, GR; Roden, DM
    Inhibition of P-glycoprotein-mediated drug transport - A unifying mechanism to explain the interaction between digoxin and quinidine
    CIRCULATION
    
    M.F. Fromm et al., "Inhibition of P-glycoprotein-mediated drug transport - A unifying mechanism to explain the interaction between digoxin and quinidine", CIRCULATION, 99(4), 1999, pp. 552-557
28. Levy, S; Maarek, M; Coumel, P; Guize, L; Lekieffre, J; Medvedowsky, JL; Sebaoun, A
    Characterization of different subsets of atrial fibrillation in general practice in France - The ALFA study
    CIRCULATION
    
    S. Levy et al., "Characterization of different subsets of atrial fibrillation in general practice in France - The ALFA study", CIRCULATION, 99(23), 1999, pp. 3028-3035
29. Murgatroyd, FD; Gibson, SM; Xie, BY; O'Nunain, S; Poloniecki, JD; Ward, DE; Malik, M; Camm, AJ
    Double-blind placebo-controlled trial of digoxin in symptomatic paroxysmalatrial fibrillation
    CIRCULATION
    
    F.D. Murgatroyd et al., "Double-blind placebo-controlled trial of digoxin in symptomatic paroxysmalatrial fibrillation", CIRCULATION, 99(21), 1999, pp. 2765-2770
30. Boutitie, F; Boissel, JP; Connolly, SJ; Camm, AJ; Cairns, JA; Julian, DG; Gent, M; Janse, NJ; Dorian, P; Frangin, G
    Amiodarone interaction with beta-blockers - Analysis of the merged EMIAT (European Myocardial Infarct Amiodarone Trial) and CAMIAT (Canadian Amiodarone Myocardial Infarction Trial) databases
    CIRCULATION
    
    F. Boutitie et al., "Amiodarone interaction with beta-blockers - Analysis of the merged EMIAT (European Myocardial Infarct Amiodarone Trial) and CAMIAT (Canadian Amiodarone Myocardial Infarction Trial) databases", CIRCULATION, 99(17), 1999, pp. 2268-2275
31. Anderson, JL; Hallstrom, AP; Epstein, AE; Pinski, SL; Rosenberg, Y; Nora, MO; Chilson, D; Cannom, DS; Moore, R
    Design and results of the Antiarrhythmics Vs Implantable Defibrillators (AVID) Registry
    CIRCULATION
    
    J.L. Anderson et al., "Design and results of the Antiarrhythmics Vs Implantable Defibrillators (AVID) Registry", CIRCULATION, 99(13), 1999, pp. 1692-1699
32. Marshall, HJ; Harris, ZI; Griffith, MJ; Holder, RL; Gammage, MD
    Prospective randomized study of ablation and pacing versus medical therapyfor paroxysmal atrial fibrillation - Effects of pacing mode and mode-switch algorithm
    CIRCULATION
    
    H.J. Marshall et al., "Prospective randomized study of ablation and pacing versus medical therapyfor paroxysmal atrial fibrillation - Effects of pacing mode and mode-switch algorithm", CIRCULATION, 99(12), 1999, pp. 1587-1592
33. Ide, T; Tsutsui, H; Kinugawa, S; Utsumi, H; Takeshita, A
    Amiodarone protects cardiac myocytes against oxidative injury by its free radical scavenging action
    CIRCULATION
    
    T. Ide et al., "Amiodarone protects cardiac myocytes against oxidative injury by its free radical scavenging action", CIRCULATION, 100(7), 1999, pp. 690-692
34. VanderLugt, JT; Mattioni, T; Denker, S; Torchiana, D; Ahern, T; Wakefield, LK; Perry, KT; Kowey, PR
    Efficacy and safety of ibutilide fumarate for the conversion of atrial arrhythmias after cardiac surgery
    CIRCULATION
    
    J.T. VanderLugt et al., "Efficacy and safety of ibutilide fumarate for the conversion of atrial arrhythmias after cardiac surgery", CIRCULATION, 100(4), 1999, pp. 369-375
35. Bauer, A; Becker, R; Freigang, KD; Senges, JC; Voss, F; Hansen, A; Muller, M; Lang, HJ; Gerlach, U; Busch, A; Kraft, P; Kubler, W; Schols, W
    Rate- and site-dependent effects of propafenone, dofetilide and the new I-Ks-blocking agent chromanol 293b on individual muscle layers of the intact canine heart
    CIRCULATION
    
    A. Bauer et al., "Rate- and site-dependent effects of propafenone, dofetilide and the new I-Ks-blocking agent chromanol 293b on individual muscle layers of the intact canine heart", CIRCULATION, 100(21), 1999, pp. 2184-2190
36. Fareh, S; Benardeau, A; Thibault, B; Nattel, S
    The T-Type Ca2+ channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs
    CIRCULATION
    
    S. Fareh et al., "The T-Type Ca2+ channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs", CIRCULATION, 100(21), 1999, pp. 2191-2197
37. Lynch, JJ; Houle, MS; Stump, GL; Wallace, AA; Gilberto, DB; Jahansouz, H; Smith, GR; Tebben, AJ; Liverton, NJ; Selnick, HG; Claremon, DA; Billman, GE
    Antiarrhythmic efficacy of selective blockade of the cardiac slowly activating delayed rectifier current, I-Ks, in canine models of malignant ischemic ventricular arrhythmia
    CIRCULATION
    
    J.J. Lynch et al., "Antiarrhythmic efficacy of selective blockade of the cardiac slowly activating delayed rectifier current, I-Ks, in canine models of malignant ischemic ventricular arrhythmia", CIRCULATION, 100(18), 1999, pp. 1917-1922
38. Kim, YH; Xie, FG; Yashima, M; Wu, TJ; Valderrabano, M; Lee, MH; Ohara, T; Voroshilovsky, O; Doshi, RN; Fishbein, MC; Qu, ZL; Garfinkel, A; Weiss, JN; Karagueuzian, HS; Chen, PS
    Role of papillary muscle in the generation and maintenance of reentry during ventricular tachycardia and fibrillation in isolated swine right ventricle
    CIRCULATION
    
    Y.H. Kim et al., "Role of papillary muscle in the generation and maintenance of reentry during ventricular tachycardia and fibrillation in isolated swine right ventricle", CIRCULATION, 100(13), 1999, pp. 1450-1459
39. Li, DS; Fareh, S; Leung, TK; Nattel, S
    Promotion of atrial fibrillation by heart failure in dogs - Atrial remodeling of a different sort
    CIRCULATION
    
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40. Lacroix, D; Extramiana, F; Delfaut, P; Adamantidis, M; Grandmougin, D; Klug, D; Kacet, S; Dupuis, B
    Factors affecting epicardial dispersion of repolarization: a mapping studyin the isolated porcine heart
    CARDIOVASCULAR RESEARCH
    
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41. PRITCHETT ELC
    EVOLUTION AND REVOLUTION IN DRUG LABELING - REGULATION OF ANTIARRHYTHMIC DRUGS BY THE FOOD-AND-DRUG-ADMINISTRATION 1962-1996
    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
    
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42. YU WC; CHEN SA; TAI CT; WEN ZC; FENG AN; DING YA; CHANG MS
    EFFECTS OF PROCAINAMIDE AND DL-SOTALOL ON THE CHANGES OF ATRIAL ELECTROPHYSIOLOGY INDUCED BY HIGH-CURRENT STIMULATION
    PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
    
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43. YU WC; CHEN SA; LEE SH; TAI CT; FENG AN; KUO BIT; DING YA; CHANG MS
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    Circulation
    
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44. TAI CT; CHEN SA; FENG AN; YU WC; CHEN YJ; CHANG MS
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    Circulation
    
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45. MYERBURG RJ; MITRANI R; INTERIAN A; CASTELLANOS A
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    Circulation
    
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46. ABDULLA R; YOUNG S; BARNES SD
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47. DONGER C; DENJOY I; BERTHET M; NEYROUD N; CRUAUD C; BENNACEUR M; CHIVORET G; SCHWARTZ K; COUMEL P; GUICHENEY P
    KVLQT1 C-TERMINAL MISSENSE MUTATION CAUSES A FORME-FRUSTE LONG-QT SYNDROME
    Circulation
    
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48. SIM I; MCDONALD KM; LAVORI PW; NORBUTAS CM; HLATKY MA
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    Circulation
    
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49. BRIGNOLE M; GIANFRANCHI L; MENOZZI C; ALBONI P; MUSSO G; BONGIORNI MG; GASPARINI M; RAVIELE A; LOLLI G; PAPARELLA N; ACQUARONE S
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