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La ricerca find articoli where soggetti phrase all words 'amino acid substitutions' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 495 riferimenti
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    1. Wong, E; Sim, J; Sim, TS
      Construction of Streptomyces jumonjinensis isopenicillin N synthase doublemutants, Ser119Ala/Glu120Gly and Thr308Ala/Thr309Val, overcomes insoluble expression in Escherichia coli

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    2. Morrison, KL; Weiss, GA
      Combinatorial alanine-scanning

      CURRENT OPINION IN CHEMICAL BIOLOGY
    3. Yoshioka, K; Kobayashi, M; Orito, E; Watanabe, K; Yano, M; Sameshima, Y; Kusakabe, A; Hirofuji, H; Fuji, A; Kuriki, J; Arao, M; Murase, K; Mizokami, M; Kakumu, S
      Biochemical response to interferon therapy correlates with interferon sensitivity-determining region in hepatitis C virus genotype 1b infection

      JOURNAL OF VIRAL HEPATITIS
    4. Stratidaki, I; Skoulika, E; Kelefiotis, D; Matrella, E; Alexandrakis, G; Economou, A; Kouroumalis, E
      NS5A mutations predict biochemical but not virological response to interferon-alpha treatment of sporadic hepatitis C virus infection in European patients

      JOURNAL OF VIRAL HEPATITIS
    5. Hu, KQ; Vierling, JM; Redeker, AG
      Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection

      JOURNAL OF VIRAL HEPATITIS
    6. Gniadkowski, M
      Evolution and epidemiology of extended-spectrum beta-lactamases (ESBLs) and ESBL-producing microorganisms

      CLINICAL MICROBIOLOGY AND INFECTION
    7. Rogozin, IB; Kondrashov, FA; Glazko, GV
      Use of mutation spectra analysis software

      HUMAN MUTATION
    8. Christiansen, J; Dean, DR; Seefeldt, LC
      Mechanistic features of the Mo-containing nitrogenase

      ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY
    9. Harris, EH
      Chlamydomonas as a model organism

      ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY
    10. Miller, MP; Kumar, S
      Understanding human disease mutations through the use of interspecific genetic variation

      HUMAN MOLECULAR GENETICS
    11. Loladze, VV; Ermolenko, DN; Makhatadze, GI
      Heat capacity changes upon burial of polar and nonpolar groups in proteins

      PROTEIN SCIENCE
    12. Lee, C; Maeng, JS; Kocher, JP; Lee, B; Yu, MH
      Cavities of alpha(1)-antitrypsin that play structural and functional roles

      PROTEIN SCIENCE
    13. Materon, IC; Palzkill, T
      Identification of residues critical for metallo-beta-lactamase function bycodon randomization and selection

      PROTEIN SCIENCE
    14. Sobrino, F; Saiz, M; Jimenez-Clavero, MA; Nunez, JI; Rosas, MF
      Foot-and-mouth disease virus: a long known virus, but a current threat

      VETERINARY RESEARCH
    15. Watanabe, K; Yoshioka, K; Terazawa, Y; Kobayashi, M; Ishigami, M; Yano, M; Fuji, A; Hattori, M; Kakumu, S
      A patient with chronic hepatitis C who obtained sustained response by retreatment of interferon after decrease of viral load and mutation in interferon sensitivity determining region

      INTERNAL MEDICINE
    16. Bradford, PA
      Extended-spectrum beta-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat

      CLINICAL MICROBIOLOGY REVIEWS
    17. Li, Y; Rey-Cuille, MA; Hu, SL
      N-linked glycosylation in the V3 region of HIV type 1 surface antigen modulates coreceptor usage in viral infection

      AIDS RESEARCH AND HUMAN RETROVIRUSES
    18. Takacs, Z; Wilhelmsen, KC; Sorota, S
      Snake alpha-neurotoxin binding site on the Egyptian cobra (Naja haje) nicotinic acetylcholine receptor is conserved

      MOLECULAR BIOLOGY AND EVOLUTION
    19. Fares, MA; Moya, A; Escarmis, C; Baranowski, E; Domingo, E; Barrio, E
      Evidence for positive selection in the capsid protein-coding region of thefoot-and-mouth disease virus (FMDV) subjected to experimental passage regimens

      MOLECULAR BIOLOGY AND EVOLUTION
    20. Wu, PF; Chang, LS
      Expression of A chain and B chain of beta-bungarotoxin from Taiwan banded krait: The functional implication of the interchain disulfide bond between A chain and B chain

      JOURNAL OF PROTEIN CHEMISTRY
    21. Asahina, Y; Izumi, N; Uchihara, M; Noguchi, O; Tsuchiya, K; Hamano, K; Kanazawa, N; Itakura, J; Miyake, S; Sakai, T
      A potent antiviral effect on hepatitis C viral dynamics in serum and peripheral blood mononuclear cells during combination therapy with high-dose daily interferon alfa plus ribavirin and intravenous twice-daily treatment with interferon beta

      HEPATOLOGY
    22. Nishiguchi, S; Ueda, T; Itoh, T; Enomoto, M; Tanaka, M; Tatsumi, N; Fukuda, K; Tamori, A; Habu, D; Takeda, T; Otani, S; Shiomi, S
      Method to detect substitutions in the interferon-sensitivity-determining region of hepatitis C virus 1b for prediction of response to interferon therapy

      HEPATOLOGY
    23. Funahashi, J; Takano, K; Yutani, K
      Are the parameters of various stabilization factors estimated from mutant human lysozymes compatible with other proteins?

      PROTEIN ENGINEERING
    24. Machingo, Q; Mazourek, M; Cameron, V
      Second-site, intragenic alterations in the gene encoding subunit II of cytochrome c oxidase from yeast can suppress two different missense mutations

      CURRENT GENETICS
    25. Thomas, NA; Bardy, SL; Jarrell, KF
      The archaeal flagellum: a different kind of prokaryotic motility structure

      FEMS MICROBIOLOGY REVIEWS
    26. Haydon, DT; Samuel, AR; Knowles, NJ
      The generation and persistence of genetic variation in foot-and-mouth disease virus

      PREVENTIVE VETERINARY MEDICINE
    27. Puig-Basagoiti, F; Saiz, JC; Forns, X; Ampurdanes, S; Gimenez-Barcons, M; Franco, S; Sanchez-Fueyo, A; Costa, J; Sanchez-Tapias, JM; Rodes, J
      Influence of the genetic heterogeneity of the ISDR and PePHD regions of hepatitis C virus on the response to interferon therapy in chronic hepatitis C

      JOURNAL OF MEDICAL VIROLOGY
    28. Witherell, GW; Beineke, P
      Statistical analysis of combined substitutions in nonstructural 5A region of hepatitis C virus and interferon response

      JOURNAL OF MEDICAL VIROLOGY
    29. Fink, T; Zachar, V; Ebbesen, P
      Biological characterization of three novel variants of IFN-alpha 13 produced by human placental trophoblast

      PLACENTA
    30. Lusida, MI; Nagano-Fujii, M; Nidom, CA; Soetjipto; Handajani, R; Fujita, T; Oka, K; Hotta, H
      Correlation between mutations in the interferon sensitivity-determining region of NS5A protein and viral load of hepatitis C virus subtypes 1b, 1c, and 2a

      JOURNAL OF CLINICAL MICROBIOLOGY
    31. Georgiou, G
      Analysis of large libraries of protein mutants using flow cytometry

      ADVANCES IN PROTEIN CHEMISTRY, VOL 55
    32. Rowan, EG
      What does beta-bungarotoxin do at the neuromuscular junction?

      TOXICON
    33. Brocchieri, L
      Phylogenetic inferences from molecular sequences: Review and critique

      THEORETICAL POPULATION BIOLOGY
    34. Menon, ST; Han, M; Sakmar, TP
      Rhodopsin: Structural basis of molecular physiology

      PHYSIOLOGICAL REVIEWS
    35. Milligan, G; Kellett, E; Dacquet, C; Dubreuil, V; Jacoby, E; Millan, MJ; Lavielle, G; Spedding, M
      S 14506: novel receptor coupling at 5-HT1A receptors

      NEUROPHARMACOLOGY
    36. Nei, M; Xu, P; Glazko, G
      Estimation of divergence times from multiprotein sequences for a few mammalian species and several distantly related organisms

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    37. Sideraki, V; Huang, WZ; Palzkill, T; Gilbert, HF
      A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfolding and aggregation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    38. Song, JM; Melera, PW
      Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein thataffects drug resistance and cooperates with TM6 to mediate [I-125]iodoarylazidoprazosin labeling

      MOLECULAR PHARMACOLOGY
    39. Si, ZH; Cayabyab, M; Sodroski, J
      Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys

      JOURNAL OF VIROLOGY
    40. Gonsky, J; Bacharach, E; Goff, SP
      Identification of residues of the Moloney murine leukemia virus nucleocapsid critical for viral DNA synthesis in vivo

      JOURNAL OF VIROLOGY
    41. Tang, SX; Murakami, T; Agresta, BE; Campbell, S; Freed, EO; Levin, JG
      Human immunodeficiency virus type 1 N-terminal capsid mutants that exhibitaberrant core morphology and are blocked in initiation of reverse transcription in infected cells

      JOURNAL OF VIROLOGY
    42. Sergel, TA; McGinnes, LW; Morrison, TG
      Mutations in the fusion peptide and adjacent heptad repeat inhibit foldingor activity of the Newcastle disease virus fusion protein

      JOURNAL OF VIROLOGY
    43. Polyak, SJ; Khabar, KSA; Paschal, DM; Ezelle, HJ; Duverlie, G; Barber, GN; Levy, DE; Mukaida, N; Gretch, DR
      Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response

      JOURNAL OF VIROLOGY
    44. Pace, CN; Horn, G; Hebert, EJ; Bechert, J; Shaw, K; Urbanikova, L; Scholtz, JM; Sevcik, J
      Tyrosine hydrogen bonds make a large contribution to protein stability

      JOURNAL OF MOLECULAR BIOLOGY
    45. Armon, A; Graur, D; Ben-Tal, N
      ConSurf: An algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information

      JOURNAL OF MOLECULAR BIOLOGY
    46. Lee, DL; Lavigne, P; Hodges, RS
      Are trigger sequences essential in the folding of two-stranded alpha-helical coiled-coils?

      JOURNAL OF MOLECULAR BIOLOGY
    47. Watanabe, H; Enomoto, N; Nagayama, K; Izumi, N; Marumo, F; Sato, C; Watanabe, M
      Number and position of mutations in the interferon (IFN) sensitivity-determining region of the gene for nonstructural protein 5A correlate with IFN efficacy in hepatitis C virus genotype 1b infection

      JOURNAL OF INFECTIOUS DISEASES
    48. Tangri, S; Ishioka, GY; Huang, XQ; Sidney, J; Southwood, S; Fikes, S; Sette, A
      Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide

      JOURNAL OF EXPERIMENTAL MEDICINE
    49. Roelofs, J; Loovers, HM; Van Haastert, PJM
      GTP gamma S regulation of a 12-transmembrane guanylyl cyclase is retained after mutation to an adenylyl cyclase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    50. Aramli, LA; Teschke, CM
      Alleviation of a defect in protein folding by increasing the rate of subunit assembly

      JOURNAL OF BIOLOGICAL CHEMISTRY
    51. Rimseliene, R; Janulaitis, A
      Mutational analysis of two putative catalytic motifs of the type IV restriction endonuclease Eco57I

      JOURNAL OF BIOLOGICAL CHEMISTRY
    52. Yasugi, M; Amino, M; Suzuki, T; Oshima, T; Yamagishi, A
      Cold adaptation of the thermophilic enzyme 3-isopropylmalate dehydrogenase

      JOURNAL OF BIOCHEMISTRY
    53. Givens, JR; McGovern, CL; Dombroski, AJ
      Formation of intermediate transcription initiation complexes at pfliD and pflgM by sigma(28) RNA polymerase

      JOURNAL OF BACTERIOLOGY
    54. Haydon, DT; Bastos, AD; Knowles, NJ; Samuel, AR
      Evidence for positive selection in foot-and-mouth disease virus capsid genes from field isolates

      GENETICS
    55. Andres, A; Kosoy, A; Garriga, P; Manyosa, J
      Mutations at position 125 in transmembrane helix III of rhodopsin affect the structure and signalling of the receptor

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    56. Takano, K; Funahashi, J; Yutani, K
      The stability and folding process of amyloidogenic mutant human lysozymes

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    57. Kononova, SV; Khokhlova, OV; Zolov, SN; Nesmeyanova, MA
      Effect of export-specific cytoplasmic chaperone, protein SecB, on secretion of Escherichia coli alkaline phosphatase

      BIOCHEMISTRY-MOSCOW
    58. Chen, JM; Stites, WE
      Energetics of side chain packing in staphylococcal nuclease assessed by systematic double mutant cycles

      BIOCHEMISTRY
    59. Gursky, O
      Solution conformation of human apolipoprotein C-1 inferred from proline mutagenesis: Far- and near-UV CD study

      BIOCHEMISTRY
    60. Bracci, L; Lozzi, L; Lelli, B; Pini, A; Neri, P
      Mimotopes of the nicotinic receptor binding site selected by a combinatorial peptide library

      BIOCHEMISTRY
    61. Dupureur, CM; Dominguez, MA
      The PD ... (D/E)XK motif in restriction enzymes: A link between function and conformation

      BIOCHEMISTRY
    62. Rankinen, T; Perusse, L; Borecki, I; Chagnon, YC; Gagnon, J; Leon, AS; Skinner, JS; Wilmore, JH; Rao, DC; Bouchard, C
      The Na+-K+-ATPase alpha 2 gene and trainability of cardiorespiratory endurance: the HERITAGE Family Study

      JOURNAL OF APPLIED PHYSIOLOGY
    63. Takatori, M; Sugata, F; Okuse, C; Iwabuchi, S; Iino, S
      Mutations in the non-structural protein 5A gene in patients with chronic hepatitis C virus 1b infection during repeated interferon treatment

      HEPATOLOGY RESEARCH
    64. Seto, NOL; Evans, SV
      Specificity in protein-carbohydrate recognition

      CURRENT ORGANIC CHEMISTRY
    65. Gotte, M; Wainberg, MA
      Biochemical mechanisms involved in overcoming HIV resistance to nucleosideinhibitors of reverse transcriptase

      DRUG RESISTANCE UPDATES
    66. Taylor, DR; Shi, ST; Lai, MMC
      Hepatitis C virus and interferon resistance

      MICROBES AND INFECTION
    67. Ikuta, K; Suzuki, S; Horikoshi, H; Mukai, T; Luftig, RB
      Positive and negative aspects of the human immunodeficiency virus protease: Development of inhibitors versus its role in AIDS pathogenesis

      MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
    68. Grishin, NV; Wolf, YI; Koonin, EV
      From complete genomes to measures of substitution rate variability within and between proteins

      GENOME RESEARCH
    69. Aizaki, H; Saito, S; Ogino, T; Miyajima, N; Harada, T; Matsuura, Y; Miyamura, T; Kohase, M
      Suppression of interferon-induced antiviral activity in cells expressing hepatitis C virus proteins

      JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
    70. Xia, XH
      Phylogenetic relationship among horseshoe crab species: Effect of substitution models on phylogenetic analyses

      SYSTEMATIC BIOLOGY
    71. Shimotohno, K
      Hepatitis C virus and its pathogenesis

      SEMINARS IN CANCER BIOLOGY
    72. Willis, MA; Bishop, B; Regan, L; Brunger, AT
      Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core

      STRUCTURE
    73. Morschhauser, J; Kohler, G; Ziebuhr, W; Blum-Oehler, G; Dobrindt, U; Hacker, J
      Evolution of microbial pathogens

      PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
    74. Wirsching, S; Michel, S; Morschhauser, J
      Targeted gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates

      MOLECULAR MICROBIOLOGY
    75. Horn, F; van der Wenden, EM; Oliveira, L; IJzerman, AP; Vriend, G
      Receptors coupling to G proteins: Is there a signal behind the sequence?

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    76. Pal, D; Chakrabarti, P
      Conformational similarity indices between different residues in proteins and alpha-helix propensities

      JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
    77. Isaka, Y; Miki, S; Kawauchi, S; Suyama, A; Sugimoto, H; Adachi, A; Hayami, M; Yoshie, O; Fujiwara, T; Sato, A
      Isolation and characterization of simian immunodeficiency virus variants that are resistant to nonnucleoside reverse transcriptase inhibitors

      ARCHIVES OF VIROLOGY
    78. Berg, T; Marques, AM; Hohne, M; Wiedenmann, B; Hopf, U; Schreier, E
      Mutations in the E2-PePHD and NS5A region of hepatitis C virus type 1 and the dynamics of hepatitis C viremia decline during interferon alfa treatment

      HEPATOLOGY
    79. Pawlotsky, JM
      Hepatitis C virus resistance to antiviral therapy

      HEPATOLOGY
    80. Wallberg, AE; Neely, KE; Hassan, AH; Gustafsson, JA; Workman, JL; Wright, APH
      Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau 1 activation domain

      MOLECULAR AND CELLULAR BIOLOGY
    81. Mas, A; Parera, M; Briones, C; Soriano, V; Martinez, MA; Domingo, E; Menendez-Arias, L
      Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance

      EMBO JOURNAL
    82. Skerker, JM; Shapiro, L
      Identification and cell cycle control of a novel pilus system in Caulobacter crescentus

      EMBO JOURNAL
    83. Provoda, CJ; Lee, KD
      Bacterial pore-forming hemolysins and their use in the cytosolic delivery of macromolecules

      ADVANCED DRUG DELIVERY REVIEWS
    84. Sheridan, PP; Panasik, N; Coombs, JM; Brenchley, JE
      Approaches for deciphering the structural basis of low temperature enzyme activity

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    85. Gomes, P; Giralt, E; Andreu, D
      Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants

      MOLECULAR IMMUNOLOGY
    86. Maekawa, S; Enomoto, N; Kurosaki, M; Nagayama, K; Marumo, F; Sato, C
      Genetic changes in the interferon sensitivity determining region of hepatitis C virus during the natural course of chronic hepatitis C

      JOURNAL OF MEDICAL VIROLOGY
    87. Devenish, RJ; Prescott, M; Boyle, GM; Nagley, P
      The oligomycin axis of mitochondrial ATP synthase: OSCP and the proton channel

      JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
    88. Korth, MJ; Katze, MG
      Evading the interferon response: Hepatitis C virus and the interferon-induced protein kinase, PKR

      HEPATITIS C VIRUSES
    89. Blazquez, J; Morosini, MI; Negri, MC; Baquero, F
      Selection of naturally occurring extended-spectrum TEM beta-lactamase variants by fluctuating beta-lactam pressure

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    90. Neuwirth, C; Labia, R; Siebor, E; Pechinot, A; Madec, S; Chaibi, EB; Kazmierczak, A
      Characterization of TEM-56, a novel beta-lactamase produced by a Klebsiella pneumoniae clinical isolate

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    91. Kakeya, H; Miyazaki, Y; Miyazaki, H; Nyswaner, K; Grimberg, B; Bennett, JE
      Genetic analysis of azole resistance in the Darlington strain of Candida albicans

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    92. Kunkel, TA; Bebenek, R
      DNA replication fidelity

      ANNUAL REVIEW OF BIOCHEMISTRY
    93. Serrano, L
      The relationship between sequence and structure in elementary folding units

      ADVANCES IN PROTEIN CHEMISTRY, VOL 53
    94. Ng, JCK; Liu, SJ; Perry, KL
      Cucumber mosaic virus mutants with altered physical properties and defective in aphid vector transmission

      VIROLOGY
    95. Feller, JA; Smallwood, S; Skiadopoulos, MH; Murphy, BR; Moyer, SA
      Comparison of identical temperature-sensitive mutations in the L polymerase proteins of Sendai and parainfluenza3 viruses

      VIROLOGY
    96. Yasuda, J; Hunter, E
      Role of matrix protein in the type D retrovirus replication cycle: Importance of the arginine residue at position 55

      VIROLOGY
    97. Choi, IR; Stenger, DC; French, R
      Multiple interactions among proteins encoded by the mite-transmitted wheatstreak mosaic tritimovirus

      VIROLOGY
    98. Hughes, AL; Green, JA; Garbayo, JM; Roberts, RM
      Adaptive diversification within a large family of recently duplicated, placentally expressed genes

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    99. Salomon, AR; Voehringer, DW; Herzenberg, LA; Khosla, C
      Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F0F1-ATPase

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    100. Lopez, M; Cocchi, F; Menotti, L; Avitabile, E; Dubreuil, P; Campadelli-Fiume, G
      Nectin2 alpha (PRR2 alpha or HveB) and nectin2 delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D

      JOURNAL OF VIROLOGY


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Documento generato il 05/06/20 alle ore 22:16:27