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Long-term and therapeutic-level hepatic gene expression of human factor IXafter naked plasmid transfer in vivo
MOLECULAR THERAPY
Suppression of colorectal cancer growth using an adenovirus vector expressing an antisense K-ras RNA
MOLECULAR THERAPY
An immunomodulatory procedure that stabilizes transgene expression and permits readministration of E1-deleted adenovirus vectors
MOLECULAR THERAPY
Adenovirus-mediated MUC1 gene transduction into human blood-derived dendritic cells
JOURNAL OF IMMUNOTHERAPY
Gene therapy for colorectal cancer - Therapeutic potential
BIODRUGS
Characterization of immortalized human chondrocytes originated from osteoarthritis cartilage
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Dynamic changes in mouse lipoproteins induced by transiently expressed human phospholipid transfer protein (PLTP): importance of PLTP in pre beta-HDLgeneration
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Emergence of anti-inflammatory monocytes in long-term surviving hosts of IL-10-transduced liver allografts
CYTOKINE
Cross-strain protection against clinical and laboratory strains of Pseudomonas aeruginosa mediated by dendritic cells genetically modified to expressCD40 ligand and pulsed with specific strains of Pseudomonas aeruginosa
HUMAN GENE THERAPY
Wild-type p53 gene transfection in human cultured sarcomas: Effect of CDDP
ONCOLOGY REPORTS
Expression of G1 cell cycle markers and the effect of adenovirus-mediated overexpression of p21Waf-1 in squamous cell carcinoma of the esophagus
INTERNATIONAL JOURNAL OF ONCOLOGY
Wild-type p53 gene transfer inhibits neointima formation in human saphenous vein by modulation of smooth muscle cell migration and induction of apoptosis
GENE THERAPY
A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the Hl loop of their fiber knob
GENE THERAPY
Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity
GENE THERAPY
Creation of a new transgene cloning site near the right ITR of Ad5 resultsin reduced enhancer interference with tissue-specific and regulatable promoters
GENE THERAPY
Steroid hormone enhancement of gene delivery to a human airway epithelial cell line in vitro and mouse airways in vivo
GENE THERAPY
Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice
GENE THERAPY
Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors
GENE THERAPY
A novel system for the production of fully deleted adenovirus vectors thatdoes not require helper adenovirus
GENE THERAPY
Efficient repetitive gene delivery to skeletal muscle using recombinant adenovirus vector containing the Coxsackievirus and adenovirus receptor cDNA
GENE THERAPY
Ex vivo and in vivo gene transfer to the peritoneal membrane in a rat model
NEPHROLOGY DIALYSIS TRANSPLANTATION
Cisplatin chemotherapy plus adenoviral p53 gene therapy in EBV-positive and -negative nasopharyngeal carcinoma
CANCER GENE THERAPY
Efficient and cancer-selective gene transfer to hepatocellular carcinoma in a rat using adenovirus vector with iodized oil esters
CANCER GENE THERAPY
Tetracycline-regulatable adenovirus vectors: pharmacologic properties and clinical potential
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Behavioral effects of infection with IL-6 adenovector
BRAIN BEHAVIOR AND IMMUNITY
In vivo adenoviral transduction of the neonatal rat cochlea and middle ear
HEARING RESEARCH
Expression of transduced HSP70 gene protects chondrocytes from stress
JOURNAL OF RHEUMATOLOGY
Primary culture of rat taste bud cells that retain molecular markers for taste buds and permit functional expression of foreign genes
NEUROSCIENCE
Is pituitary gene therapy realistic?
CLINICAL ENDOCRINOLOGY
Efficient and ligand-dependent regulated erythropoietin production by naked DNA injection and in vivo electroporation
AMERICAN JOURNAL OF KIDNEY DISEASES
Adenoviral p53 gene therapy promotes heat-induced apoptosis in a nasopharyngeal carcinoma cell line
INTERNATIONAL JOURNAL OF HYPERTHERMIA
Gene therapy for hepatocellular carcinoma using two recombinant adenovirusvectors with alpha-fetoprotein promoter and Cre/lox P system
JOURNAL OF VIROLOGICAL METHODS
Gene therapy in vascular medicine: recent advances and future perspectives
PHARMACOLOGY & THERAPEUTICS
Gene therapy for Fabry disease
JOURNAL OF INHERITED METABOLIC DISEASE
Potential cancer therapy with the fragile histidine triad gene - Review ofthe preclinical studies
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Gene transfer for angiogenesis in coronary artery disease
ANNUAL REVIEW OF MEDICINE
The effect of CD28/B7 blockade on alloreactive T and B cells after liver cell transplantation
TRANSPLANTATION
Neoadjuvant therapy with interleukin-12-loaded polylactic acid microspheres reduces local recurrence and distant metastases
SURGERY
Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
Gene transfer by adenovirus in rabbit iris sphincter muscle
OPHTHALMIC RESEARCH
Gene therapy of cystic fibrosis
MONATSSCHRIFT KINDERHEILKUNDE
Gene therapy in ophthalmology - Survey of perspectives for corneal diseases
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
Overexpression of cdk inhibitor p16(INK4a) by adenovirus vector inhibits cardiac hypertrophy in vitro and in vivo: a novel strategy for the gene therapy of cardiac hypertrophy
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Novel centrifugal method for simple and highly efficient adenovirus-mediated green fluorescence protein gene transduction into human monocyte-deriveddendritic cells
JOURNAL OF IMMUNOLOGICAL METHODS
Antigen-pulsed dendritic cells expressing macrophage-derived chemokine elicit Th2 responses and promote specific humoral immunity
JOURNAL OF CLINICAL INVESTIGATION
Depolarization strongly induces human cytomegalovirus major immediate-early promoter/enhancer activity in neurons
JOURNAL OF BIOLOGICAL CHEMISTRY
Gene therapy utilizing the Cre/loxP system selectively suppresses tumor growth of disseminated carcinoembryonic antigen-producing cancer cells
INTERNATIONAL JOURNAL OF CANCER
Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/5-fluorocytosine enhanced by the Cre/loxP system in the orthotopic gastric carcinoma model
CANCER RESEARCH
Co-administration of adenovirus vector expressing CTLA4-Ig prolongs transgene expression in the brain of mice sensitized with adenovirus
BRAIN RESEARCH
Ectopic expression of the coxsackievirus and adenovirus receptor increasessusceptibility to adenoviral infection in the human cervical cancer cell line, SiHa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
In vivo gene transfer to cerebral white matter lesions with a recombinant adenovirus vector
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Reversible integration of the dominant negative retinoid receptor gene forex vivo expansion of hematopoietic stem/progenitor cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Fibroblast-mediated delivery of growth factor complementary DNA into mousejoints induces chondrogenesis but avoids the disadvantages of direct viralgene transfer
ARTHRITIS AND RHEUMATISM
Stable transduction of actively dividing cells via a novel adenoviral/episomal vector
MOLECULAR THERAPY
Enzymatic corrections for cells derived from Fabry disease patients by a recombinant adenovirus vector
JOURNAL OF HUMAN GENETICS
Gene transfer to primary acute myeloid leukaemia blasts and myeloid leukaemia cell lines
CYTOKINES CELLULAR & MOLECULAR THERAPY
Gene therapy strategies for colon cancer
MOLECULAR MEDICINE TODAY
Therapeutic approaches for haemophilia
EXPERT OPINION ON THERAPEUTIC PATENTS
HSV-1 infected cell proteins influence tetracycline-regulated transgene expression
JOURNAL OF GENE MEDICINE
Trehalose expression confers desiccation tolerance on human cells
NATURE BIOTECHNOLOGY
Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4(+) T cells
NATURE MEDICINE
Transfer of SV40 temperature-sensitive early gene into human epidermal keratinocytes by the recombinant adenovirus vector
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
Gene therapy in wound repair and regeneration
WOUND REPAIR AND REGENERATION
Continuous erythropoietin delivery by muscle-targeted gene transfer using in vivo electroporation
HUMAN GENE THERAPY
In vivo expression of the LacZ gene delivered to mouse lung by means of synthetic microspheres
RUSSIAN JOURNAL OF GENETICS
Glioma/glioblastoma-specific adenoviral gene expression using the nestin gene regulator
GENE THERAPY
An integrin-targeted non-viral vector for pulmonary gene therapy
GENE THERAPY
Anti-inflammatory gene therapy directed at the airway epithelium
GENE THERAPY
Recombinant adenovirus vectors with knobless fibers for targeted gene transfer
GENE THERAPY
Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression
GENE THERAPY
A radiation-controlled molecular switch for use in gene therapy of cancer
GENE THERAPY
Repeat administration of DNA/liposomes to the nasal epithelium of patientswith cystic fibrosis
GENE THERAPY
Gene therapy for gastric cancer: problems and prospects
SURGICAL ONCOLOGY-OXFORD
Recent advances in liver-directed gene therapy: implications for the treatment of dyslipidemia
CURRENT OPINION IN LIPIDOLOGY
Overexpression of the wild-type p53 gene inhibits NF-kappa B activity and synergizes with aspirin to induce apoptosis in human colon cancer cells
ONCOGENE
Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type p53 (Ad-p53)
CANCER GENE THERAPY
Adenovirus-mediated overexpression of Fas induces apoptosis of gliomas
CANCER GENE THERAPY
In vivo efficacy and toxicity of 5-fluorocytosine/cytosine deaminase gene therapy for malignant gliomas mediated by adenovirus
CANCER GENE THERAPY
Adenovirus-mediated transfer of p53-related genes induces apoptosis of human cancer cells
JAPANESE JOURNAL OF CANCER RESEARCH
Adenoviral transduction of human E-selectin into isolated, perfused, rat aortic segments: an ex vivo model for studying leukocyte-endothelial interactions
JOURNAL OF LEUKOCYTE BIOLOGY
Intratumoral interleukin 2 for renal-cell carcinoma by direct gene transfer of a plasmid DNA/DMRIE/DOPE lipid complex
WORLD JOURNAL OF UROLOGY
Enzyme/prodrug gene therapy for human colon cancer cells using adenovirus-mediated transfer of the Escherichia coli cytosine deaminase gene driven bya CAG promoter associated with 5-fluorocytosine administration
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Adenovirus-mediated transfer of beta-galactosidase and prourokinase genes into vein grafts
CHINESE MEDICAL JOURNAL
Gene transfer into hippocampal slice cultures with an adenovirus vector driven by cytomegalovirus promoter: Stable co-expression of green fluorescentprotein and lacZ genes
BRAIN RESEARCH BULLETIN
Ex vivo gene delivery using an adenovirus vector in treatment for cartilage defects
JOURNAL OF RHEUMATOLOGY
Establishment of stromal cell line from an MDS RA patient which induced anapoptopic change in hematopoietic and leukemic cells in vitro
EXPERIMENTAL HEMATOLOGY
Induction of immune responses in newborn lambs following enteric immunization with a human adenovirus vaccine vector
VACCINE
Gene transfer of recombinant endothelial nitric oxide synthase to liver invivo and in vitro
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein
MOLECULAR BRAIN RESEARCH
Effect of bile and pancreatic juice on adenoviral-mediated gene delivery -Implications on the feasibility of gene delivery through ERCP
DIGESTIVE DISEASES AND SCIENCES
Interleukin-10 gene transfer improves the survival rate of mice inoculatedwith Escherichia coli
CRITICAL CARE MEDICINE
G1 cyclins are involved in the mechanism of cardiac myocyte hypertrophy induced by angiotensin II
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
Enhanced selective gene expression by adenovirus vector using Cre/loxP regulation system for human carcinoembryonic antigen-producing carcinoma
ONCOLOGY
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice
LIFE SCIENCES
BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons
JOURNAL OF NEUROCHEMISTRY
Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons
JOURNAL OF NEUROCHEMISTRY
Viral vectors for gene delivery and gene therapy within the endocrine system
JOURNAL OF ENDOCRINOLOGY
Macrophage inflammatory protein 3 alpha transgene attracts dendritic cellsto established murine tumors and suppresses tumor growth
JOURNAL OF CLINICAL INVESTIGATION