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Carbon dioxide pressure-concentration relationship in arterial and mixed venous blood during exercise
JOURNAL OF APPLIED PHYSIOLOGY
The genetics and pathology of oxidative phosphorylation
NATURE REVIEWS GENETICS
Lactic acidosis in metformin therapy: searching for a link with metformin in reports of 'metformin-associated lactic acidosis'
DIABETES OBESITY & METABOLISM
Vastus medialis muscle oxygenation trends during a simulated 20-km cycle time trial
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
Oxygenation trends in vastus lateralis muscle during incremental and intense anaerobic cycle exercise in young men and women
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
Prevalence of A-to-G mutation at nucleotide 3243 of the mitochondrial tRNA(Leu(UUR)) gene in Japanese patients with diabetes mellitus and end stage renal disease
JOURNAL OF HUMAN GENETICS
Mitochondrial toxicity and HIV therapy
SEXUALLY TRANSMITTED INFECTIONS
Metformin retention independent of renal failure in intestinal occlusion
DIABETES & METABOLISM
Congenital lactic acidosis: Evaluation of the properties of the A199T natural variant of human pyruvate dehydrogenase E1 alpha by in vitro mutation
MOLECULAR GENETICS AND METABOLISM
Dichloroacetate reduces diaphragmatic lactate formation but impairs respiratory performance
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
A global approach to energy metabolism in an experimental model of sepsis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Selected controversies in cardiopulmonary resuscitation
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
Discordance between cerebral oxygen and glucose metabolism, and hemodynamics in a mitochondrial encephalomyopathy, lactic acidosis, and strokelike episode patient
JOURNAL OF NEUROIMAGING
De novo mutation in the mitochondrial tRNA(Leu(UUR)) gene (A3243G) with rapid segregation resulting in MELAS in the offspring
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
A novel mutation in the mitochondrial 16S rRNA gene in a patient with MELAS syndrome, diabetes mellitus, hyperthyroidism and cardiomyopathy
JOURNAL OF BIOMEDICAL SCIENCE
Functional characterization of novel mutations in the human cytochrome b gene
EUROPEAN JOURNAL OF HUMAN GENETICS
Maternally inherited deafness associated with a T1095C mutation in the mDNA
EUROPEAN JOURNAL OF HUMAN GENETICS
Relative fitness of carriers of the mitochondrial DNA mutation 3243A > G
EUROPEAN JOURNAL OF HUMAN GENETICS
Pyruvate/dichloroacetate supply during reperfusion accelerates recovery ofcardiac energetics and improves mechanical function following cardioplegicarrest
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
A mitochondrial encephalo-myo-neuropathy with a nucleotide position 3271 (T-C) point mutation in the mitochondrial DNA
NEUROMUSCULAR DISORDERS
The metabolic toxicities of antiretroviral therapy
INTERNATIONAL JOURNAL OF STD & AIDS
Severe lactic acidosis and thiamine administration in an HIV-infected patient on HAART
INTERNATIONAL JOURNAL OF STD & AIDS
Early recognition of acute cardiovascular beriberi by interpretation of hemodynamics
JOURNAL OF CLINICAL ANESTHESIA
Search for mitochondrial DNA, mutation ate position 3243 in German patients with a positive family history of maternal diabetes mellitus
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
Molecular and clinical aspects of mitochondrial diabetes mellitus
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
Metformin, the rebirth of a biguanide: mechanism of action and place in the prevention and treatment of insulin resistance
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
A novel mitochondrial DNA mutation and a mutation in the Notch3 gene in a patient with myopathy and CADASIL
JOURNAL OF MOLECULAR MEDICINE-JMM
Serial measurement of arterial lactate concentrations as a prognostic indicator in relation to the incidence of disseminated intravascular coagulation in patients with systemic inflammatory response syndrome
SURGERY TODAY
An 80-year-old mitochondrial disease patient with A3243G tRNA(Leu) ((UUR))gene presenting cardiac dysfunction as the main symptom
INTERNAL MEDICINE
Severe metabolic acidosis and heart failure due to thiamine deficiency
NUTRITION
Free radical spin trap alpha-phenyl-N-tert-butyl-nitron inhibits caspase-3activation and reduces brain damage following a severe forebrain ischemic injury
FREE RADICAL BIOLOGY AND MEDICINE
Dichloroacetate treatment for severe refractory metabolic acidosis during neonatal sepsis
PEDIATRIC INFECTIOUS DISEASE JOURNAL
Mitochondrial cytopathy in adults: What we know so far
CLEVELAND CLINIC JOURNAL OF MEDICINE
Elevated lactate levels in hospitalized persons with HIV infection
AIDS RESEARCH AND HUMAN RETROVIRUSES
Concepts of the strong ion difference applied to large volume resuscitation
JOURNAL OF INTENSIVE CARE MEDICINE
Contraindications to metformin therapy in patients with Type 2 diabetes - a population-based study of adherence to prescribing guidelines
DIABETIC MEDICINE
Metformin-associated lactic acidosis
JOURNAL OF EMERGENCY MEDICINE
Aerobic conditioning in patients with mitochondrial myopathies: Physiological, biochemical, and genetic effects
ANNALS OF NEUROLOGY
Late-onset mitochondrial DNA depletion: DNA copy number, multiple deletions, and compensation
ANNALS OF NEUROLOGY
Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Diffuse hepatic intravascular carcinomatous embolization resulting in fatal liver failure: A clinicopathologic study of 4 cases
PATHOLOGY RESEARCH AND PRACTICE
Lactate: May I have your votes please?
INTENSIVE CARE MEDICINE
Effects of magnesium sulfate on tissue lactate and malondialdehyde levels in experimental head trauma
INTENSIVE CARE MEDICINE
Hearing impairment in patients with 3243A -> G mtDNA mutation: phenotype and rate of progression
HUMAN GENETICS
Effects of nimodipine on tissue lactate and malondialdeyde levels in experimental head trauma
ANAESTHESIA AND INTENSIVE CARE
The relationship between metformin therapy and the fasting plasma lactate in type 2 diabetes: The Fremantle Diabetes Study
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia)
VETERINARY PATHOLOGY
Lactic acidosis: pathophysiology, diagnosis and treatment
NETHERLANDS JOURNAL OF MEDICINE
Assessment of peripheral muscle function
ARCHIVOS DE BRONCONEUMOLOGIA
Acute metabolic acidosis decreases muscle protein synthesis but not albumin synthesis in humans
AMERICAN JOURNAL OF KIDNEY DISEASES
Use of base in the treatment of severe acidemic states
AMERICAN JOURNAL OF KIDNEY DISEASES
Chorea induced by thiamine deficiency in hemodialysis patients
AMERICAN JOURNAL OF KIDNEY DISEASES
Metabolic testing in mitochondrial disease
SEMINARS IN NEUROLOGY
Treatment of mitochondrial cytopathies
SEMINARS IN NEUROLOGY
Nutritional lactate spikes: quantitative antagonism by dichloroacetate
NUTRITION RESEARCH
Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy
AIDS
Management of hyperlactatemia: no need for routine lactate measurements
AIDS
An argument for mitochondrial toxicity in highly active antiretroviral therapy-induced lipoatrophy
AIDS
Episodic aphasia with residual effects in a patient with progressive dementia resulting from a mitochondrial cytopathy (MELAS)
APHASIOLOGY
Mitochondria and the heart
CURRENT OPINION IN CARDIOLOGY
What factors are associated with hyperlactatemia after cardiac surgery characterized by well-maintained oxygen delivery and a normal postoperative course? A retrospective study
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
Wobble modification defect in tRNA disturbs codon-anticodon interaction ina mitochondrial disease
EMBO JOURNAL
A rare etiology of hepatic steatosis associated with lactic acidosis: the toxicity of antiviral nucleoside analogues
ANNALES DE PATHOLOGIE
Oral agents for the treatment of type 2 diabetes mellitus: Pharmacology, toxicity, and treatment
ANNALS OF EMERGENCY MEDICINE
Infantile presentation of the mtDNA A3243G tRNA(Leu(UUR)) mutation
NEUROPEDIATRICS
Antibody response in sheep following immunization with Streptococcus bovisin different adjuvants
VETERINARY RESEARCH COMMUNICATIONS
Better correction of metabolic acidosis, blood pressure control, and phagocytosis with bicarbonate compared to lactate solution in acute peritoneal dialysis
ARTIFICIAL ORGANS
Barth's syndrome-like disorder: A new phenotype with a maternally inherited A3243G substitution of mitochondrial DNA (MELAS mutation)
AMERICAN JOURNAL OF MEDICAL GENETICS
Effect of lateral positions on tissue oxygenation in the critically ill
HEART & LUNG
Metabolic effects of metaproterenol overdose: Hypokalemia, hyperglycemia and hyperlactatemia
VETERINARY AND HUMAN TOXICOLOGY
Ketoacidosis: an unusual presentation of MELAS
JOURNAL OF INHERITED METABOLIC DISEASE
Confusion after antibiotics
LANCET
Diet-dependent shifts in the bacterial population of the rumen revealed with real-time PCR
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Optical imaging techniques (Histochemical, immunohistochemical, and in situ hybridization staining methods) to visualize mitochondria
METHODS IN CELL BIOLOGY, VOL 65
Dichloroacetate: Population pharmacokinetics with a pharmacodynamic sequential link model
JOURNAL OF CLINICAL PHARMACOLOGY
Initial effect of sodium bicarbonate on intracellular pH depends on the extracellular nonbicarbonate buffering capacity
CRITICAL CARE MEDICINE
Sodium bicarbonate and intracellular acidosis: Myth or reality?
CRITICAL CARE MEDICINE
The hepatosplanchnic area is not a common source of lactate in patients with severe sepsis
CRITICAL CARE MEDICINE
Effect of NaHCO3 on cardiac energy metabolism and contractile function during hypoxemia
CRITICAL CARE MEDICINE
Effects of epinephrine on intestinal oxygen supply and mucosal tissue oxygen tension in pigs
CRITICAL CARE MEDICINE
The hepatosplanchnic area and hyperlactatemia: A tale of two lactates
CRITICAL CARE MEDICINE
A selective inhibitor for inducible nitric oxide synthase improves hypotension and lactic acidosis in canine endotoxic shock
CRITICAL CARE MEDICINE
Hyperlactatemia in acute liver failure: Decreased clearance versus increased production
CRITICAL CARE MEDICINE
Tubulointerstitial nephritis associated with a novel mitochondrial point mutation
KIDNEY INTERNATIONAL
Population pharmacokinetics of intramuscular quinine in children with severe malaria
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Orthotopic liver transplantation for mitochondrial respiratory chain disorders: A study of 5 children
TRANSPLANTATION
Mitochondrial disease and stroke
STROKE
Genetic diseases of the mitochondrial DNA.
SALUD PUBLICA DE MEXICO
Recurrent encephalopathy after small bowel resection. Implication of D-lactate.
REVUE NEUROLOGIQUE
The effect of lactate on sex differences in rat renal tubular energy-dependent transport of the organic cation amantadine
PHARMACOLOGY
Kynurenic acid influences the respiratory parameters of rat heart mitochondria
PHARMACOLOGY
Mechanisms of disease: The pathogenesis of vasodilatory shock
NEW ENGLAND JOURNAL OF MEDICINE
Epileptic phenotypes associated with mitochondrial disorders
NEUROLOGY
Symptomatic hyperlactemia in patients infected with the human immunodeficiency virus treated with nucleoside analogues
MEDICINA CLINICA
Symptomatic hyperlactemia in patients infected with the human immunodeficiency virus treated with nucleoside analogues
MEDICINA CLINICA
Effect of stavudine on mitochondrial genome and fatty acid oxidation in lean and obese mice
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Mitochondrial DNA depletion, near-fatal metabolic acidosis, and liver failure in an HIV-infected child treated with combination antiretroviral therapy
JOURNAL OF PEDIATRICS
Caveats when considering ketogenic diets for the treatment of pyruvate dehydrogenase complex deficiency
JOURNAL OF PEDIATRICS
Both L- and D-lactate contribute to metabolic acidosis in diarrheic calves
JOURNAL OF NUTRITION