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Recent advances in feeding suppressing agents: potential therapeutic strategy for the treatment of obesity
EXPERT OPINION ON THERAPEUTIC PATENTS
Pathophysiology and treatment of IgA nephropathy in children
PEDIATRIC NEPHROLOGY
Neuropeptide YY1 receptors are involved in nociception and inflammation
M S-MEDECINE SCIENCES
The neuropeptide YY5 receptor mediates the blockade of "photic-like" NMDA-induced phase shifts in the golden hamster
JOURNAL OF NEUROSCIENCE
Blockade of pancreatic polypeptide-sensitive neuropeptide Y (NPY) receptors by agonist peptides is prevented by modulators of sodium transport. Implications for receptor signaling and regulation
PEPTIDES
Origins of the many NPY-family receptors in mammals
PEPTIDES
NPY in invertebrates: molecular answers to altered functions during evolution
PEPTIDES
Cloning and characterization of rhesus monkey neuropeptide Y receptor subtypes
PEPTIDES
Neuropeptide YY2 receptor signalling mechanisms in the human glioblastoma cell line LN319
PEPTIDES
Different binding sites for the neuropeptide YY1 antagonists 1229U91 and J-104870 on human Y1 receptors
PEPTIDES
Food intake inhibition and reduction in body weight gain in rats treated with GI264879A, a non-selective NPY-Y1 receptor antagonist
PEPTIDES
Emerging functions of neuropeptide YY2 receptors in the brain
PEPTIDES
The mPVN mediates blockade of NPY-induced feeding by a Y5 receptor antagonist: a c-FOS analysis
PEPTIDES
Neurohormonal regulation of secretion from isolated rat stomach ECL cells:a critical reappraisal
REGULATORY PEPTIDES
KO's and organisation of peptidergic feeding behavior mechanisms
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Neuropeptide Y stimulates food consumption through multiple receptors in goldfish
PHYSIOLOGY & BEHAVIOR
GABAergic and NPY-Y-1 network in the medial amygdala: a neuroanatomical basis for their functional interaction
NEUROPHARMACOLOGY
Leptin activates anorexigenic POMC neurons through a neural network in thearcuate nucleus
NATURE
Identification of potent and selective neuropeptide YY1 receptor agonists with orexigenic activity in vivo
MOLECULAR PHARMACOLOGY
Increased expression of the neuropeptide Y receptor Y-1 gene in the medialamygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone
JOURNAL OF NEUROCHEMISTRY
Drosophila neuropeptide F mediates integration of chemosensory stimulationand conditioning of the nervous system by food
JOURNAL OF NEUROBIOLOGY
Neuropeptide YY5 receptor antagonist CGP71683A: the effects on food intakeand anxiety-related behavior in the rat
EUROPEAN JOURNAL OF PHARMACOLOGY
Agonist and antagonist activities on human NPFF2 receptors of the NPY ligands GR231118 and BIBP3226
BRITISH JOURNAL OF PHARMACOLOGY
Effects of a selective neuropeptide YY2 receptor antagonist, BIIE0246, on Y-2 receptors at peripheral neuroeffector junctions
BRITISH JOURNAL OF PHARMACOLOGY
Constitutive neuropeptide YY4 receptor expression in human colonic adenocarcinoma cell lines
BRITISH JOURNAL OF PHARMACOLOGY
Lack of effects by sigma ligands on neuropeptide Y-induced G-protein activation in rat hippocampus and cerebellum
BRAIN RESEARCH
Design of the Y-1-receptor-selective cyclic peptide based on the C-terminal sequence of neuropeptide Y
JOURNAL OF PEPTIDE RESEARCH
The role of NPY in metabolic homeostasis: implications for obesity therapy
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Patent focus on new anti-obesity agents: September 1999-February 2000
EXPERT OPINION ON THERAPEUTIC PATENTS
Neuropeptide Y in the paraventricular nucleus of the hypothalamus stimulates colonic transit by peripheral cholinergic and central CRF pathways
NEUROGASTROENTEROLOGY AND MOTILITY
Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family
JOURNAL OF PEPTIDE SCIENCE
Cloning and transcriptional expression of a leucokinin-like peptide receptor from the Southern cattle tick, Boophilus microplus (Acari : Ixodidae)
INSECT MOLECULAR BIOLOGY
Association of neuropeptide YY1 receptors with glutamate-positive and NPY-positive neurons in rat hippocampal cultures
EUROPEAN JOURNAL OF NEUROSCIENCE
Molecular manipulation of G-protein-coupled receptors: A new avenue into drug discovery
CURRENT MEDICINAL CHEMISTRY
Characterisation of G-protein-coupled receptors by antibodies
CURRENT MEDICINAL CHEMISTRY
Peptide self-association in aqueous trifluoroethanol monitored by pulsed field gradient NMR diffusion measurements
JOURNAL OF BIOMOLECULAR NMR
Sub-population of cultured hippocampal astrocytes expresses neuropeptide YY1 receptors
GLIA
Neuropeptide Y-Y1 receptor antisense oligodeoxynucleotide increases the infarct volume after middle cerebral artery occlusion ln rats
NEUROSCIENCE
Neuropeptide YY5 receptor protein in the cortical/limbic system and brainstem of the rat: Expression on gamma-aminobutyric acid and corticotropin-releasing hormone neurons
NEUROSCIENCE
[D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide YY5 receptor agonist with dramatic effects on food intake
PEPTIDES
Primary structures of PYY, [Pro(34)]PYY, and PYY-(3-36) confer different conformations and receptor selectivity
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Neuropeptide YY1 receptor mediated mesenteric vasoconstriction in the pig in vivo
REGULATORY PEPTIDES
Evidence that NPYY1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats
REGULATORY PEPTIDES
2-36[K-4,RYYSA(19-23)]PP a novel Y5-receptor preferring ligand with strongstimulatory effect on food intake
REGULATORY PEPTIDES
PYY regulates pancreatic exocrine secretion through multiple receptors in the awake rat
DIGESTIVE DISEASES AND SCIENCES
Neuropeptide Y1-and Y2-receptor-mediated cardiovascular effects in the anesthetized guinea pig, rat, and rabbit
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Role of NPYY1 receptors in cardiovascular control in the conscious rabbit
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Stimulation of the gonadotropic axis by the neuropeptide Y receptor Y1 antagonist/Y4 agonist 1229U91 in the male rat
NEUROENDOCRINOLOGY
Receptors for NPY in peripheral tissues bioassays
LIFE SCIENCES
Pharmacological characterization of I-125-1229U91 binding to Y1 and Y4 neuropeptide Y/peptide YY receptors
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Behavioural neuroscience and child psychopathology: Insights from model systems
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES
Pharmacological characterization of the cloned neuropeptide Y y(6) receptor
EUROPEAN JOURNAL OF PHARMACOLOGY
Structure-affinity relationships of C-terminal cyclic analogue of neuropeptide Y for the Y-1-receptor
CHEMICAL & PHARMACEUTICAL BULLETIN
Pharmacology and quantitative structure-activity relationships of imidazolylpropylguanidines with mepyramine-like substructures as non-peptide neuropeptide YY1 receptor antagonists
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIBO3304 (Y1) and CGP71683A (Y5)
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
FMRFamides exert a unique modulation of rodent pancreatic polypeptide sensitive neuropeptide Y (NPY) receptors
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Food intake regulation in rodents: Y-5 or Y1NPY receptors or both?
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Effects of a selective neuropeptide YY1 receptor antagonist BIBP 3226 on double peaked vasoconstrictor responses to periarterial nerve stimulation incanine splenic arteries
BRITISH JOURNAL OF PHARMACOLOGY
Neuropeptide Y regulates intracellular calcium through different signalling pathways linked to a Y-1-receptor in rat mesenteric small arteries
BRITISH JOURNAL OF PHARMACOLOGY
BIIE0246, a potent and highly selective non-peptide neuropeptide YY2 receptor antagonist
BRITISH JOURNAL OF PHARMACOLOGY
[I-125]-GR231118: a high affinity radioligand to investigate neuropeptide YY1 and Y-4 receptors
BRITISH JOURNAL OF PHARMACOLOGY
Normal feeding behavior, body weight and leptin response require the neuropeptide YY2 receptor
NATURE MEDICINE
Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
1,3-disubstituted benzazepines as neuropeptide YY1 receptor antagonists
BIOORGANIC & MEDICINAL CHEMISTRY
Molecular dynamics of NPYY1 receptor activation
BIOORGANIC & MEDICINAL CHEMISTRY
The neuropeptide YY1 receptor is a somatic receptor on dorsal root ganglion neurons and a postsynaptic receptor on somatostatin dorsal horn neurons
EUROPEAN JOURNAL OF NEUROSCIENCE
Regional distribution of Y-receptor subtype mRNAs in rat brain
EUROPEAN JOURNAL OF NEUROSCIENCE
Role of membrane conductances and protein synthesis in subjective day phase advances of the hamster circadian clock by neuropeptide Y
EUROPEAN JOURNAL OF NEUROSCIENCE
Alterations in neuropeptide Y, tyrosine hydroxylase, and Y-receptor subtype distribution following spinal nerve injury to rats
PAIN
The human superior cervical ganglion: neuropeptides and peptide receptors
NEUROSCIENCE LETTERS
Neuropeptide YY1 receptor polymorphism as a prognostic predictor in Japanese patients with IgA nephropathy
CLINICAL NEPHROLOGY
The cloned guinea pig neuropeptide Y receptor Y-1 conforms to other mammalian Y-1 receptors
PEPTIDES
Neuropeptide Y receptor alterations in the hypothalamus of lactating rats
PEPTIDES
Evidence of a specific pancreatic polypeptide receptor in rat arterial smooth muscle
PEPTIDES
Differential regulation of mRNAs for neuropeptide Y and its receptor subtypes in widespread areas of the rat limbic system during kindling epileptogenesis
MOLECULAR BRAIN RESEARCH
Helical structure and self-association in a 13 residue neuropeptide YY2 receptor agonist: relationship to biological activity
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
Cardiorespiratory responses to intracerebroventricular injection of neuropeptide Y in anaesthetised dogs
REGULATORY PEPTIDES
NPYY2 receptor agonist, N-acetyl [Leu(28),Leu(31)]NPY24-36, reduces renal vasoconstrictor activity in anaesthetised dogs
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
The corticotropin-release inhibitory factor hypothesis: A review of the evidence for the existence of inhibitory as well as stimulatory hypophysiotropic regulation of adrenocorticotropin secretion and biosynthesis
ENDOCRINE REVIEWS
Structure-activity analysis of N-acetyl[Leu(28,31)] NPY 24-36: a potent neuropeptide YY2 receptor agonist
NEUROPEPTIDES
Antisense mRNA for NPY-Y-1 receptor in the medial preoptic area increases prolactin secretion
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
Recent advances in the development of neuropeptide Y receptor antagonists
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 34
Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M-1 muscarinic acetylcholine receptors
MOLECULAR PHARMACOLOGY
Extensive alternative splicing in the 5 '-untranslated region of the rat and human neuropeptide YY5 receptor genes regulates receptor expression
JOURNAL OF NEUROCHEMISTRY
Regulation of neuropeptide Y release by neuropeptide Y receptor ligands and calcium channel antagonists in hypothalamic slices
JOURNAL OF NEUROCHEMISTRY
1,3-disubstituted benzazepines as novel, potent, selective neuropeptide YY1 receptor antagonists
JOURNAL OF MEDICINAL CHEMISTRY
Phencyclidine and dizocilpine modulate dopamine release from rat nucleus accumbens via sigma receptors
EUROPEAN JOURNAL OF PHARMACOLOGY
Neuropeptide Y-induced contraction is mediated by neuropeptide YY2 and Y-4receptors in the rat colon
EUROPEAN JOURNAL OF PHARMACOLOGY
Amygdalar neuropeptide Y Y-1 receptors mediate the anxiolytic-like actionsof neuropeptide Y in the social interaction test
EUROPEAN JOURNAL OF PHARMACOLOGY
Gi-protein alpha-subunit mRNA antisense oligonucleotide inhibition of Gi-coupled receptor contractile activity in the epididymis of the guinea-pig
BRITISH JOURNAL OF PHARMACOLOGY
Influence of TASP-V, a novel neuropeptide Y (NPY) Y-2 agonist, on nasal and bronchial responses evoked by histamine in anaesthetized pigs and in humans
BRITISH JOURNAL OF PHARMACOLOGY
An immunohistochemical marker for Wallerian degeneration of fibers in the central and peripheral nervous system
BRAIN RESEARCH
Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Decreased responsiveness of vascular postjunctional alpha(1)-, alpha(2)-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure
ACTA PHYSIOLOGICA SCANDINAVICA
MOLECULAR MODELING OF THE NPY BINDING-SITE ON THE Y-1 RECEPTOR
JOURNAL OF MOLECULAR MODELING
CENTRAL CONTROL OF FEEDING-BEHAVIOR BY NEUROPEPTIDE-Y
Current pharmaceutical design
MICROSATELLITE MARKER CONTENT MAPPING OF 12 CANDIDATE GENES FOR OBESITY - ASSEMBLY OF 7 OBESITY SCREENING PANELS FOR AUTOMATED GENOTYPING
PCR methods and applications
DOWN-REGULATED NPY RECEPTOR SUBTYPE-5 MESSENGER-RNA EXPRESSION IN GENETICALLY-OBESE MOUSE-BRAIN
NeuroReport
NPY Y-1 RECEPTORS IN THE DORSAL PERIAQUEDUCTAL GRAY-MATTER REGULATE ANXIETY IN THE SOCIAL-INTERACTION TEST
NeuroReport
THE MURINE Y-1 RECEPTOR 5' UPSTREAM SEQUENCE DIRECTS CELL-SPECIFIC AND DEVELOPMENTALLY-REGULATED LACZ EXPRESSION IN TRANSGENIC MICE CNS
European journal of neuroscience