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Thromboxane mediates pulmonary hypertension and lung inflammation during hyperacute lung rejection
JOURNAL OF APPLIED PHYSIOLOGY
The humoral barrier to transplantation of the liver: Is it more real than apparent?
LIVER TRANSPLANTATION
Xenotransplantation of the liver: Is more complement control needed?
LIVER TRANSPLANTATION
Decreased cyclin B1 expression contributes to G(2) delay in human brain tumor cells after treatment with camptothecin
NEURO-ONCOLOGY
Vascular differences detected by MRI for metastatic versus nonmetastatic breast and prostate cancer xenografts
NEOPLASIA
1 alpha,25-Dihydroxyvitamin D-3 and its analogues, EB1089 and CB1093, profoundly inhibit the in vitro proliferation of the human hepatoblastoma cell line HepG2
ANZ journal of surgery
A prevention strategy for circumventing drug resistance in cancer chemotherapy
CURRENT PHARMACEUTICAL DESIGN
Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it?
DRUG RESISTANCE UPDATES
Xenografts: are the risks so great that we should not proceed?
MICROBES AND INFECTION
Filovirus-pseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo
NATURE BIOTECHNOLOGY
Tools for pretargeted radioimmunotherapy
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
In vivo evaluation of bismuth-labeled monoclonal antibody comparing DTPA-derived bifunctional chelates
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
Accumulation of radiolabeled anti-CEA antibody (mT84.66) in the case of multiple LS174T tumors in a nude mouse model
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
Treatment of meningeal breast cancer xenografts in the rat using an anti-P185/HER2 antibody
CLINICAL CANCER RESEARCH
Frederine, a new and promising protector against doxorubicin-induced cardiotoxicity
CLINICAL CANCER RESEARCH
Biodistribution properties of (111)Indium-labeled C-functionalized trans-cyclohexyl diethylenetriaminepentaacetic acid humanized 3S193 diabody and F(ab ')(2) constructs in a breast carcinoma xenograft model
CLINICAL CANCER RESEARCH
Schedule dependency of antitumor activity in combination therapy with capecitabine/5 '-deoxy-5-fluorouridine and docetaxel in breast cancer models
CLINICAL CANCER RESEARCH
Involvement of microsomal cytochrome P450 and cytosolic thymidine phosphorylase in 5-fluorouracil formation from tegafur in human liver
CLINICAL CANCER RESEARCH
Why drugs fail: Of mice and men revisited
CLINICAL CANCER RESEARCH
Relation between 9-aminocamptothecin systemic exposure and tumor response in human solid tumor xenografts
CLINICAL CANCER RESEARCH
Preclinical antitumor activity and pharmacodynamic studies with the farnesylprotein transferase inhibitor R115777 in human breast cancer
CLINICAL CANCER RESEARCH
Therapeutic advantage of (90)Yttrium-versus (131)Iodine-labeled PAM4 antibody in experimental pancreatic cancer
CLINICAL CANCER RESEARCH
Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: Further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums
CLINICAL CANCER RESEARCH
Schedule-dependent activity of topotecan in OVCAR-3 ovarian carcinoma xenograft: Pharmacokinetic and pharmacodynamic evaluation
CLINICAL CANCER RESEARCH
Sequence-dependent enhancement of cytotoxicity produced by ecteinascidin 743 (ET-743) with doxorubicin or paclitaxel in soft tissue sarcoma cells
CLINICAL CANCER RESEARCH
Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model
CLINICAL CANCER RESEARCH
A phase I study of irinotecan in pediatric patients: A Pediatric Oncology Group Study
CLINICAL CANCER RESEARCH
Single-dose versus fractionated radioimmunotherapy of human colon carcinoma xenografts using I-131-labeled multivalent CC49 single-chain Fvs(1)
CLINICAL CANCER RESEARCH
The immunological barrier to xenotransplantation
IMMUNITY
Evidence for target-specific outgrowth from subpopulations of grafted human dopamine neurons
MICROSCOPY RESEARCH AND TECHNIQUE
Quick disposal of dead cardiomyocytes: An ultimate proof of their apoptosis
JOURNAL OF HEART AND LUNG TRANSPLANTATION
Cardiac hyperacute, rejection: A new look or a skewed look at an old problem?
JOURNAL OF HEART AND LUNG TRANSPLANTATION
Salt-independent abnormality of antimicrobial activity in cystic fibrosis airway surface fluid
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
New models of the tracheal airway define the glandular contribution to airway surface fluid and electrolyte composition
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Effects of chemotherapy on invasion and metastasis of oral cavity cancer in mice
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Synthesis, characterization, and labeling with Tc-99m/Re-188 of peptide conjugates containing a dithia-bisphosphine chelating agent
BIOCONJUGATE CHEMISTRY
A polar substituent containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[I-131]iodobenzbate ([I-131]SGMIB)
BIOCONJUGATE CHEMISTRY
Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and T84.66 minibody: Comparison to radioiodinated fragments
BIOCONJUGATE CHEMISTRY
Vinflunine, the latest Vinca alkaloid in clinical development - A review of its preclinical anticancer properties
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Role of radiation dosimetry in radioimmunotherapy planning and treatment dosing
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Preclinical development of metalloproteasis inhibitors in cancer therapy
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
X-ray microanalysis of airway surface liquid collected in cystic fibrosis mice
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Effects of concomitant use of doxifluridine, radiotherapy and immunotherapy in patients with advanced cervical cancer
ONCOLOGY REPORTS
Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines
ONCOLOGY REPORTS
Interleukin-10 expression is correlated with growth fraction in human non-small cell lung cancer xenografts
INTERNATIONAL JOURNAL OF ONCOLOGY
Potentiation of antitumor activity of irinotecan by chemically modified oligonucleotides
INTERNATIONAL JOURNAL OF ONCOLOGY
Positively charged templates for labeling internalizing antibodies: comparison of N-succinimidyl 5-Iodo-3-pyridinecarboxylate and the D-amino acid peptide KRYRR
NUCLEAR MEDICINE AND BIOLOGY
Potential F-18-labeled biomarkers for epidermal growth factor receptor tyrosine kinase
NUCLEAR MEDICINE AND BIOLOGY
Synthesis and evaluation of a macrocyclic bifunctional chelating agent foruse with bismuth radionuclides
NUCLEAR MEDICINE AND BIOLOGY
Optimisation of cyclotron production parameters for the Bi-209(alpha, 2n) At-211 reaction related to biomedical use of At-211
APPLIED RADIATION AND ISOTOPES
Reduced growth in response to ganciclovir treatment of subcutaneous xenografts expressing HSV-tk in the vascular compartment
GENE THERAPY
Survival of macroencapsulated allogeneic parathyroid tissue one year aftertransplantation in nonimmunosuppressed humans
CELL TRANSPLANTATION
Role of pancreatic polypeptide as a market of transplanted insulin-producing fetal pig cells
CELL TRANSPLANTATION
Protection of xenografts by a combination of immunoisolation and a single dose of anti-CD4 antibody
CELL TRANSPLANTATION
Neural xenotransplantation: Pretreatment of porcine embryonic nigral tissue with anti-gal antibodies and complement is not toxic for the dopaminergicneurons
CELL TRANSPLANTATION
A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice
EUROPEAN JOURNAL OF CANCER
Clinical trials of Herceptin (R) (trastuzumab)
EUROPEAN JOURNAL OF CANCER
First-line, single-agent Herceptin (R) (trastuzumab) in metastatic breast cancer: a preliminary report
EUROPEAN JOURNAL OF CANCER
Capecitabine: a novel agent for the treatment of solid tumors
ANTI-CANCER DRUGS
Search for metabolites of ecteinascidin 743, a novel, marine-derived, anti-cancer agent, in man
ANTI-CANCER DRUGS
Antitumor activity of XR5944, a novel and potent topoisomerase poison
ANTI-CANCER DRUGS
Drug-targeting strategies in cancer therapy
CURRENT OPINION IN GENETICS & DEVELOPMENT
Impact of the tumour bed effect on micro environment, radiobiological hypoxia and the outcome of fractionated radiotherapy of human FaDu squamous-cell carcinoma growing in the nude mouse
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Interleukin-6 in islet xenograft rejection
TRANSPLANT INTERNATIONAL
Analysis of potential porcine endogenous retrovirus (PERV) transmission ina whole-organ xenotransplantation model without interfering microchimerism
TRANSPLANT INTERNATIONAL
Anticancer prodrugs for application in monotherapy: Targeting hypoxia, tumor-associated enzymes, and receptors
CURRENT MEDICINAL CHEMISTRY
Preclinical evaluation of new anthracyclines
CURRENT MEDICINAL CHEMISTRY
Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines
CURRENT MEDICINAL CHEMISTRY
Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases
ANNALS OF ONCOLOGY
Experimental radioimmunotherapy with Re-186-MAG3-A7 anti-colorectal cancermonoclonal antibody: Comparison with I-131-counterpart
ANNALS OF NUCLEAR MEDICINE
Effect of combination therapy with matrix metalloproteinase inhibitor MMI-166 and mitomycin C on the growth and liver metastasis of human colon cancer
JAPANESE JOURNAL OF CANCER RESEARCH
UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery
JAPANESE JOURNAL OF CANCER RESEARCH
Antitumor activity and pharmacokinetics of TAS-106, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine
JAPANESE JOURNAL OF CANCER RESEARCH
Pre-transplant blood transfusion induces tolerance to hamster cardiac xenografts in athymic nude rats
XENOTRANSPLANTATION
Human thrombin and FXa mediate porcine endothelial cell activation; modulation by expression of TFPI-CD4 and hirudin-CD4 fusion proteins
XENOTRANSPLANTATION
Maturation of xenoantibody gene expression during the humoral immune response of rats to hamster xenografts
XENOTRANSPLANTATION
Porcine endogenous retroviruses (PERVs): Generation of specific antibodies, development of an immunoperoxidase assay (IPA) and inhibition by AZT
XENOTRANSPLANTATION
Sensitive and specific immunological detection methods for porcine endogenous retroviruses applicable to experimental and clinical xenotransplantation
XENOTRANSPLANTATION
Different mechanisms mediate the rejection of porcine neurons and endothelial cells transplanted into the rat brain
XENOTRANSPLANTATION
Low molecular weight dextran sulfate prevents complement activation and delays hyperacute rejection in pig-to-human xenotransplantation models
XENOTRANSPLANTATION
A primate model for discordant pig to primate kidney xenotransplantation without hyperacute graft rejection
JOURNAL OF INVESTIGATIVE SURGERY
Retinoic acid enhances the cytotoxic effects of gemcitabine and cisplatin in pancreatic adenocarcinoma cells
PANCREAS
Phase I and pharmacokinetic study of ecteinaseidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors
JOURNAL OF CLINICAL ONCOLOGY
Phase I study of topotecan plus cranial radiation for glioblastoma multiforme: Results of Radiation Therapy Oncology Group Trial 9507
JOURNAL OF CLINICAL ONCOLOGY
Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: A pediatric oncology group phase II study
JOURNAL OF CLINICAL ONCOLOGY
Improved outcome for patients with middle ear rhabdomyosarcoma: A children's oncology group study
JOURNAL OF CLINICAL ONCOLOGY
Phase I trial of pegylated liposomal doxorubicin and docetaxel in advancedbreast cancer
JOURNAL OF CLINICAL ONCOLOGY
Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: An Intergroup Rhabdomyosarcoma Study
JOURNAL OF CLINICAL ONCOLOGY
Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity
JOURNAL OF CELLULAR BIOCHEMISTRY
26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer
JOURNAL OF CELLULAR BIOCHEMISTRY
A physiologically based pharmacokinetic analysis of capecitabine, a tripleprodrug of 5-FU, in humans: The mechanism for tumor-selective accumulationof 5-FU
PHARMACEUTICAL RESEARCH
Impact of bone marrow transplantation on type I diabetes
WORLD JOURNAL OF SURGERY
Distribution of intraventricularly administered antiamyloid-beta peptide (A beta) antibody in the mouse brain
JOURNAL OF NEUROSCIENCE RESEARCH
Patterns of proliferation related to vasculature in human head-and-neck carcinomas before and after transplantation in nude mice
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Repopulation of FaDu human squamous cell carcinoma during fractionated radiotherapy correlates with reoxygenation
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Topotecan selectively enhances the radioresponse of human small-cell lung carcinoma and glioblastoma multiforme xenografts in nude mice
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Local hyperthermia, radiation, and chemotherapy in recurrent breast canceris feasible and effective except for inflammatory disease
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Tumor oximetry: Demonstration of an enhanced dynamic mapping procedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate R3327-AT1 rat tumor
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Tumor oxygenation after radiotherapy, chemotherapy, and/or hyperthermia predicts tumor free survival
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Antitumor effect of radioactive cisplatin (Pt-191) on nude mice
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS