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    1. Tatebe, S; Unate, H; Sinicrope, FA; Sakatani, T; Sugamura, K; Makino, M; Ito, H; Savaraj, N; Kaibara, N; Kuo, MT
      Expression of heavy subunit of gamma-glutamylcysteine synthetase (gamma-GCSh) in human colorectal carcinoma

      INTERNATIONAL JOURNAL OF CANCER
    2. Podgorski, I; Bull, AW
      Energy-dependent export of the 13-oxooctadecadienoic acid-glutathione conjugate from HT-29 cells and plasma membrane vesicles

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
    3. Cnubben, NHP; Rietjens, IMCM; Wortelboer, H; van Zanden, J; van Bladeren, PJ
      The interplay of glutathione-related processes in antioxidant defense

      ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
    4. Walsh, AC; Feulner, JA; Reilly, A
      Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: Association with glutathione levels and drugresistance in the national cancer institute tumor cell line panel

      TOXICOLOGICAL SCIENCES
    5. Rappa, G; Lorico, A; Hildinger, M; Fodstad, O; Baum, C
      Novel bicistronic retroviral vector expressing gamma-glutamylcysteine synthetase and the multidrug resistance protein 1 (MRP1) protects cells from MRP1-effluxed drugs and alkylating agents

      HUMAN GENE THERAPY
    6. Iida, T; Kijima, H; Urata, Y; Goto, S; Ihara, Y; Oka, M; Kohno, S; Scanlon, KJ; Kondo, T
      Hammerhead ribozyme against gamma-glutamylcysteine synthetase sensitizes human colonic cancer cells to cisplatin by down-regulating both the glutathione synthesis and the expression of multidrug resistance proteins

      CANCER GENE THERAPY
    7. Hooiveld, GJEJ; van Montfoort, JE; Meijer, DKF; Muller, M
      Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport (vol 12, pg 13, 2000)

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    8. Soini, Y; Jarvinen, K; Kaarteenaho-Wiik, R; Kinnula, V
      The expression of P-glycoprotein and multidrug resistance proteins 1 and 2(MRP1 and MRP2) in human malignant mesothelioma

      ANNALS OF ONCOLOGY
    9. Komuro, Y; Udagawa, Y; Susumu, N; Aoki, D; Kubota, T; Nozawa, S
      Paclitaxel and SN-38 overcome cisplatin resistance of ovarian cancer cell lines by down-regulating the influx and efflux system of cisplatin

      JAPANESE JOURNAL OF CANCER RESEARCH
    10. Sadzuka, Y; Sugiyama, T; Suzuki, T; Sonobe, T
      Enhancement of the activity of doxorubicin by inhibition of glutamate transporter

      TOXICOLOGY LETTERS
    11. Schrenk, D; Baus, PR; Ermel, N; Klein, C; Vorderstemann, B; Kauffmann, HM
      Up-regulation of transporters of the MRP family by drugs and toxins

      TOXICOLOGY LETTERS
    12. Legare, D; Richard, D; Mukhopadhyay, R; Stierhof, YD; Rosen, BP; Haimeur, A; Papadopoulou, B; Ouellette, M
      The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    13. Soini, Y; Napankangas, U; Jarvinen, K; Kaarteenaho-Wiik, R; Paakko, P; Kinnula, VL
      Expression of gamma-glutamyl cysteine synthetase in nonsmall cell lung carcinoma

      CANCER
    14. Pallis, M; Grundy, M; Turzanski, J; Kofler, R; Russell, N
      Mitochondrial membrane sensitivity to depolarization in acute myeloblasticleukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status

      BLOOD
    15. de Bittencourt, PIH; Curi, R
      Antiproliferative prostaglandins and the MRP/GS-X pump role in cancer immunosuppression and insight into new strategies in cancer gene therapy

      BIOCHEMICAL PHARMACOLOGY
    16. Lin-Lee, YC; Tatebe, S; Savaraj, N; Ishikawa, T; Kuo, MT
      Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status

      BIOCHEMICAL PHARMACOLOGY
    17. Furuta, K; Tomokiyo, K; Satoh, T; Watanabe, Y; Suzuki, M
      Designed prostaglandins with neurotrophic activities

      CHEMBIOCHEM
    18. Ishikawa, T; Kuo, MT; Furuta, K; Suzuki, M
      The human multidrug resistance-associated protein (MRP) gene family: From biological function to drug molecular design

      CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    19. Renes, J; de Vries, EGE; Jansen, PLM; Muller, M
      The (patho)physiological functions of the MRP family

      DRUG RESISTANCE UPDATES
    20. van der Kolk, DM; de Vries, EGE; van Putten, WLJ; Verdonck, LF; Ossenkoppele, GJ; Verhoef, GEG; Vellenga, E
      P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia

      CLINICAL CANCER RESEARCH
    21. Wild, AC; Mulcahy, RT
      Regulation of gamma-glutamylcysteine synthetase subunit gene expression: Insights into transcriptional control of antioxidant defenses

      FREE RADICAL RESEARCH
    22. Perek, N; Prevot, N; Koumanov, F; Frere, D; Sabido, O; Beauchesne, P; Dubois, F
      Involvement of the glutathione S-conjugate compounds and the MRP protein in Tc-99m-tetrofosmin and Tc-99m-sestamibi uptake in glioma cell lines

      NUCLEAR MEDICINE AND BIOLOGY
    23. Hooiveld, GJEJ; van Montfoort, JE; Meijer, DKF; Muller, M
      Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    24. Lu, SC
      Regulation of glutathione synthesis

      CURRENT TOPICS IN CELLULAR REGULATION, VOL 36
    25. Walczak, HA; Dean, JV
      Vacuolar transport of the glutathione conjugate of trans-cinnamic acid

      PHYTOCHEMISTRY
    26. Ikegami, Y; Tatebe, S; Lin-Lee, YC; Xie, QW; Ishikawa, T; Kuo, MT
      Induction of MRP1 and gamma-glutamylcysteine synthetase gene expression byinterleukin 1 beta is mediated by nitric oxide-related signalings in humancolorectal cancer cells

      JOURNAL OF CELLULAR PHYSIOLOGY
    27. Oguri, T; Isobe, T; Suzuki, T; Nishio, K; Fujiwara, Y; Katoh, O; Yamakido, M
      Increased expression of the MRP5 gene is associated with exposure to platinum drugs in lung cancer

      INTERNATIONAL JOURNAL OF CANCER
    28. Hooijberg, JH; Pinedo, HM; Vrasdonk, C; Priebe, W; Lankelma, J; Broxterman, HJ
      The effect of glutathione on the ATPase activity of MRP1 in its natural membranes

      FEBS LETTERS
    29. Suzuki, M; Noyori, R; Langstrom, B; Watanabe, Y
      Molecular design of prostaglandin probes in brain research: High, specificbinding to a novel prostacyclin receptor in the central nervous system

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
    30. Evers, R; de Haas, M; Sparidans, R; Beijnen, J; Wielinga, PR; Lankelma, J; Borst, P
      Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

      BRITISH JOURNAL OF CANCER
    31. Sundkvist, E; Jaeger, R; Sager, G
      Leukotriene C-4 (LTC4) does not share a cellular efflux mechanism with cGMP: characterisation of cGMP transport by uptake to inside-out vesicles fromhuman erythrocytes

      BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
    32. Choi, J; Opalenik, SR; Wu, WC; Thompson, JA; Forman, HJ
      Modulation of glutathione synthetic enzymes by acidic fibroblast growth factor

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    33. Quan, Z; Ozawa, T; Sato, M; Umezawa, Y
      Screening method for substrates of multidrug resistance-associated protein

      ANALYTICA CHIMICA ACTA
    34. Murdoch, PD; Kratochwil, NA; Parkinson, JA; Patriarca, M; Sadler, PJ
      A novel dinuclear diaminoplatinum(II) glutathione macrochelate

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    35. McLellan, LI; Wolf, CR
      Glutathione and glutathione-dependent enzymes in cancer drug resistance

      DRUG RESISTANCE UPDATES
    36. Hayes, JD; McLellan, LI
      Glutathione and glutathione-dependent enzymes represent a Co-ordinately regulated defence against oxidative stress

      FREE RADICAL RESEARCH
    37. Furuta, K; Hosoya, T; Tomokiyo, K; Okuda, S; Kuniyasu, A; Nakayama, H; Ishikawa, T; Suzuki, M
      [S-35]S-[5-(4-benzoylphenyl)pentyl]glutathione: A versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    38. Oguri, T; Fujiwara, Y; Miyazaki, M; Takahashi, T; Kurata, T; Yokozaki, M; Ohashi, N; Isobe, T; Katoh, O; Yamakido, M
      Induction of gamma-glutamylcysteine synthetase gene expression by platinumdrugs in peripheral mononuclear cells of lung cancer patients

      ANNALS OF ONCOLOGY
    39. Ueda, K; Suzuki, H; Akiyama, S; Sugiyama, Y
      Differences in substrate specificity among glutathione conjugates (GS-X) pump family members: Comparison between multidrug resistance-associated protein and a novel transporter expressed on a cisplatin-resistant cell line (KCP-4)

      JAPANESE JOURNAL OF CANCER RESEARCH
    40. Lu, SC
      Regulation of hepatic glutathione synthesis: current concepts and controversies

      FASEB JOURNAL
    41. Griffith, OW
      Biologic and pharmacologic regulation of mammalian glutathione synthesis

      FREE RADICAL BIOLOGY AND MEDICINE
    42. Sakamoto, H; Hara, H; Hirano, K; Adachi, T
      Enhancement of glucuronosyl etoposide transport by glutathione in multidrug resistance-associated protein-overexpressing cells

      CANCER LETTERS
    43. Akiyama, S; Chen, ZS; Sumizawa, T; Furukawa, T
      Resistance to cisplatin

      ANTI-CANCER DRUG DESIGN
    44. Kusuzaki, K; Hirata, M; Hashiguchi, S; Takeshita, H; Murata, H; Ashihara, T; Hirasawa, Y
      Acquisition of multidrug resistance in osteosarcomas, analyzed by doxorubicin binding assay, and histologic response to chemotherapy

      ANTICANCER RESEARCH
    45. Manome, Y; Watanabe, M; Futaki, K; Ishiguro, H; Iwagami, S; Noda, K; Dobashi, H; Ochiai, Y; Ohara, Y; Sanuki, K; Kunieda, T; Ohno, T
      Development of a syngenic brain-tumor model resistant to chloroethyl-nitrosourea using a methylguanine DNA methyltransferase cDNA

      ANTICANCER RESEARCH
    46. Roelofsen, H; Hooiveld, GJEJ; Koning, H; Havinga, R; Jansen, PLM; Muller, M
      Glutathione S-conjugate transport in hepatocytes entering the cell cycle is preserved by a switch in expression from the apical MRP2 to the basolateral MRP1 transporting protein

      JOURNAL OF CELL SCIENCE
    47. Iida, T; Mori, E; Mori, K; Goto, S; Urata, Y; Oka, M; Kohno, S; Kondo, T
      Co-expression of gamma-glutamylcysteine synthetase sub-units in response to cisplatin and doxorubicin in human cancer cells

      INTERNATIONAL JOURNAL OF CANCER
    48. Hipfner, DR; Deeley, RG; Cole, SPC
      Structural, mechanistic and clinical aspects of MRP1

      BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
    49. TWENTYMAN P; BAGRIJ T
      THE INFLUENCE OF GLUTATHIONE METABOLISM ON MULTIDRUG-RESISTANCE IN MRP-OVEREXPRESSING CELLS

      DRUG RESISTANCE UPDATES
    50. OUELLETTE M; LEGARE D; HAIMEUR A; GRONDIN K; ROY G; BROCHU C; PAPADOPOULOU B
      ABC TRANSPORTERS IN LEISHMANIA AND THEIR ROLE IN DRUG-RESISTANCE

      DRUG RESISTANCE UPDATES
    51. KIGAWA J; MINAGAWA Y; CHENG XS; TERAKAWA N
      GAMMA-GLUTAMYL CYSTEINE SYNTHETASE UP-REGULATES GLUTATHIONE AND MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN IN PATIENTS WITH CHEMORESISTANT EPITHELIAL OVARIAN-CANCER

      Clinical cancer research
    52. CLYNES M; DALY C; NICAMHLAOIBH R; CRONIN D; ELLIOTT C; OCONNOR R; ODOHERTY T; CONNOLLY L; HOWLETT A; SCANLON K
      RECENT DEVELOPMENTS IN DRUG-RESISTANCE AND APOPTOSIS RESEARCH

      Critical reviews in oncology/hematology
    53. DEBITTENCOURT PIH; CURI R; WILLIAMS JF
      GLUTATHIONE METABOLISM AND GLUTATHIONE S-CONJUGATE EXPORT ATPASE (MRP1 GS-X PUMP) ACTIVITY IN CANCER - I - DIFFERENTIAL EXPRESSION IN HUMANCANCER CELL-LINES/

      Biochemistry and molecular biology international
    54. DEBITTENCOURT PIH; SENNA SM; VIDOR AC; MIYASAKA CK; CURI R; WILLIAMS JF
      GLUTATHIONE METABOLISM AND GLUTATHIONE S-CONJUGATE EXPORT ATPASE (MRP1 GS-X PUMP) ACTIVITY IN CANCER - II - CELL-TO-CELL VARIABILITY, RELATION WITH CELLULAR ACTIVATION STATE AND FUNCTIONAL ABSENCE OF GS-X PUMPIN LYMPHOCYTES/

      Biochemistry and molecular biology international
    55. DEBITTENCOURT PIH; MIYASAKA CK; CURI R; WILLIAMS JF
      EFFECTS OF THE ANTIPROLIFERATIVE CYCLOPENTENONE PROSTAGLANDIN A(1) ONGLUTATHIONE METABOLISM IN HUMAN CANCER-CELLS IN CULTURE

      Biochemistry and molecular biology international
    56. Ishikawa, T; Kuo, MT; Furuta, K; Suzuki, M
      A new aspect on glutathione-associated biological function of MRP/GS-X pump and its gene expression

      CYTOTECHNOLOGY
    57. Kinoshita, S; Suzuki, H; Ito, K; Kume, K; Shimizu, T; Sugiyama, Y
      Transfected rat cMOAT is functionally expressed on the apical membrane in Madin-Darby canine kidney (MDCK) cells

      PHARMACEUTICAL RESEARCH
    58. OGRETMEN B; BAHADORI H; MCCAULEY M; BOYLAN A; GREEN M; SAFA AR
      LACK OF CORRELATION OF MRP AND GAMMA-GLUTAMYLCYSTEINE SYNTHETASE OVEREXPRESSION WITH DOXORUBICIN RESISTANCE DUE TO INCREASED APOPTOSIS IN SV40 LARGE T-ANTIGEN-TRANSFORMED HUMAN MESOTHELIAL CELLS

      Cancer chemotherapy and pharmacology
    59. MA JG; MALIEPAARD M; KOLKER HJ; VERWEIJ J; SCHELLENS JHM
      ABROGATED ENERGY-DEPENDENT UPTAKE OF CISPLATIN IN A CISPLATIN-RESISTANT SUBLINE OF THE HUMAN OVARIAN-CANCER CELL-LINE IGROV-1

      Cancer chemotherapy and pharmacology
    60. Suzuki, H; Sugiyama, Y
      Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2

      SEMINARS IN LIVER DISEASE
    61. OGRETMEN B; BAHADORI HR; MCCAULEY MD; BOYLAN A; GREEN MR; SAFA AR
      COORDINATED OVER-EXPRESSION OF THE MRP AND GAMMA-GLUTAMYLCYSTEINE SYNTHETASE GENES, BUT NOT MDR1, CORRELATES WITH DOXORUBICIN RESISTANCE INHUMAN-MALIGNANT MESOTHELIOMA CELL-LINES

      International journal of cancer
    62. KIUCHI Y; SUZUKI H; HIROHASHI T; TYSON CA; SUGIYAMA Y
      CDNA CLONING AND INDUCIBLE EXPRESSION OF HUMAN MULTIDRUG-RESISTANCE ASSOCIATED PROTEIN-3 (MRP3)

      FEBS letters
    63. CHEN ZS; MUTOH M; SUMIZAWA T; FURUKAWA T; HARAGUCHI M; TANI A; SAIJO N; KONDO T; AKIYAMA SI
      AN ACTIVE EFFLUX SYSTEM FOR HEAVY-METALS IN CISPLATIN-RESISTANT HUMANKB CARCINOMA-CELLS

      Experimental cell research
    64. LEE K; BELINSKY MG; BELL DW; TESTA JR; KRUH GD
      ISOLATION OF MOAT-B, A WIDELY EXPRESSED MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER-RELATEDTRANSPORTER

      Cancer research
    65. SHARP SY; SMITH V; HOBBS S; KELLAND LR
      LACK OF A ROLE FOR MRP1 IN PLATINUM DRUG-RESISTANCE IN HUMAN OVARIAN-CANCER CELL-LINES

      British Journal of Cancer
    66. OGURI T; FUJIWARA Y; ISOBE T; KATOH O; WATANABE H; YAMAKIDO M
      EXPRESSION OF GAMMA-GLUTAMYLCYSTEINE SYNTHETASE (GAMMA-GCS) AND MULTIDRUG-RESISTANCE ASSOCIATED PROTEIN (MRP), BUT NOT HUMAN CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER (CMOAT), GENES CORRELATES WITH EXPOSURE OF HUMAN LUNG CANCERS TO PLATINUM DRUGS

      British Journal of Cancer
    67. LACAVE R; COULET F; RICCI S; TOUBOUL E; FLAHAULT A; RATEAU JG; CESARI D; LEFRANC JP; BERNAUDIN JF
      COMPARATIVE-EVALUATION BY SEMIQUANTITATIVE REVERSE-TRANSCRIPTASE POLYMERASE-CHAIN-REACTION OF MDR1, MRP AND GSTP GENE-EXPRESSION IN BREAST CARCINOMAS

      British Journal of Cancer
    68. WELTERS MJP; FICHTINGERSCHEPMAN AMJ; BAAN RA; FLENS MJ; SCHEPER RJ; BRAAKHUIS BJM
      ROLE OF GLUTATHIONE, GLUTATHIONE S-TRANSFERASES AND MULTIDRUG RESISTANCE-RELATED PROTEINS IN CISPLATIN SENSITIVITY OF HEAD AND NECK-CANCER CELL-LINES

      British Journal of Cancer
    69. MORROW CS; SMITHERMAN PK; TOWNSEND AJ
      COMBINED EXPRESSION OF MULTIDRUG-RESISTANCE PROTEIN (MRP) AND GLUTATHIONE-S-TRANSFERASE P1-1 (GSTP1-1) IN MCF7 CELLS AND HIGH-LEVEL RESISTANCE TO THE CYTOTOXICITIES OF ETHACRYNIC-ACID BUT NOT OXAZAPHOSPHORINESOR CISPLATIN

      Biochemical pharmacology
    70. BARRAND MA; BAGRIJ T; NEO SY
      MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN - A PROTEIN DISTINCT FROM P-GLYCOPROTEIN INVOLVED IN CYTOTOXIC DRUG EXPULSION

      General pharmacology
    71. ISHIKAWA T; LI ZS; LU YP; REA PA
      THE GS-X PUMP IN PLANT, YEAST, AND ANIMAL-CELLS - STRUCTURE, FUNCTION, AND GENE-EXPRESSION

      Bioscience reports
    72. EVERS R; CNUBBEN NHP; WIJNHOLDS J; VANDEEMTER L; VANBLADEREN PJ; BORST P
      TRANSPORT OF GLUTATHIONE PROSTAGLANDIN-A CONJUGATES BY THE MULTIDRUG-RESISTANCE PROTEIN-1

      FEBS letters
    73. NARASAKI F; OKA M; NAKANO R; IKEDA K; FUKUDA M; NAKAMURA T; SODA H; NAKAGAWA M; KUWANO M; KOHNO S
      HUMAN CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER (CMOAT) IS EXPRESSED IN HUMAN LUNG, GASTRIC, AND COLORECTAL-CANCER CELLS

      Biochemical and biophysical research communications
    74. ISHIKAWA T
      THE MOLECULAR-STRUCTURE AND PHYSIOLOGICAL -FUNCTION OF GS-X PUMP FAMILY

      Nippon Nogei Kagakukaishi
    75. AKIMARU K; KUO MT; FURUTA K; SUZUKI M; NOYORI R; ISHIKAWA T
      INDUCTION OF MRP GS-X PUMP AND CELLULAR-RESISTANCE TO ANTICANCER PROSTAGLANDINS/

      Cytotechnology
    76. YAMAZAKI M; SUZUKI H; SUGIYAMA Y
      RECENT ADVANCES IN CARRIER-MEDIATED HEPATIC-UPTAKE AND BILIARY-EXCRETION OF XENOBIOTICS

      Pharmaceutical research


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Documento generato il 13/08/20 alle ore 14:42:33