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In vitro-inhibition of shear-induced platelet aggregation by verapamil
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
Comparative antiplatelet efficacy of a novel, nonpeptide GPIIb/IIIa antagonist (XV454) and abciximab (c7E3) in flow models of thrombosis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Mechanisms of platelet aggregation
CURRENT OPINION IN HEMATOLOGY
Expression of the amino-terminal domain of platelet glycoprotein Ib alpha:Exploitation of a calmodulin tag for determination of its functional activity
PROTEIN EXPRESSION AND PURIFICATION
Pharmacological control of platelet function
PHARMACOLOGICAL RESEARCH
Effects of ticlopidine on von Willebrand factor-mediated shear-induced platelet activation and aggregation
PLATELETS
Two distinct mechanisms are involved in stent thrombosis under flow conditions
PLATELETS
The vascular biology of the glycoprotein Ib-IX-V complex
THROMBOSIS AND HAEMOSTASIS
Dynamic aspects of platelet adhesion under flow
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Platelet adhesion receptors and (patho)physiological thrombus formation
HISTOLOGY AND HISTOPATHOLOGY
Methods and models to evaluate shear-dependent and surface reactivity-dependent antithrombotic efficacy
THROMBOSIS RESEARCH
Specific inhibiting characteristics of tetramethylpyrazine, one of the active ingredients of the Chinese herbal medicine 'chuanxiong,' on platelet thrombus formation under high shear rates
THROMBOSIS RESEARCH
Regulation of von Willebrand factor finding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal
JOURNAL OF BIOLOGICAL CHEMISTRY
Phenotype changes resulting in high-affinity binding of von Willebrand factor to recombinant glycoprotein Ib-IX: analysis of the platelet-type von Willebrand disease mutations
BLOOD
Verotoxin-1-induced up-regulation of adhesive molecules renders microvascular endothelial cells thrombogenic at high shear stress
BLOOD
Epitope mapping of inhibitory antibodies against platelet glycoprotein Ib alpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ib alpha
BLOOD
Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactions
BLOOD
Platelet GP Ib/IX/V complex: physiological role
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
Platelet thrombus formation on collagen at high shear rates is mediated byvon Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
A global platelet test of thrombosis and thrombolysis detects a prothrombotic state in some patients with non-insulin dependent diabetes and in some patients with stroke
PLATELETS
Structural determinants within platelet glycoprotein Ib alpha involved in its binding to von Willebrand factor
PLATELETS
Platelet surface P-selectin molecules increased after exposing platelet toa high shear flow
INTERNATIONAL ANGIOLOGY
Type 2M vWD resulting from a lysine deletion within a four lysine residue repeat in the A1 loop of von Willebrand factor
THROMBOSIS AND HAEMOSTASIS
Role of the leucine-rich domain of platelet GPIb alpha in correct post-translational processing - The Nancy I Bernard-Soulier mutation expressed on CHO cells
THROMBOSIS AND HAEMOSTASIS
Changes in glycoprotein expression after platelet activation: Differences between in vitro and in vivo studies
THROMBOSIS AND HAEMOSTASIS
A common polymorphism flanking the ATG initiator codon of GPIb alpha does not affect expression and is not a major risk factor for arterial thrombosis
THROMBOSIS AND HAEMOSTASIS
Morphological differences between GPIb antibody-induced and shear stress-induced platelet aggregates
HAEMOSTASIS
Characterization of murine anti-glycoprotein ib monoclonal antibodies thatdifferentiate between shear-induced and ristocetin/botrocetin-induced glycoprotein Ib-von Willebrand Factor interaction
HAEMOSTASIS
The high molecular mass, glycoprotein Ib-binding protein flavocetin-A induces only small platelet aggregates in vitro
THROMBOSIS RESEARCH
Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha(IIB)beta(3) - Studies in human platelets and transfected Chinese hamster ovary cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Novel gain-of-function mutations of platelet glycoprotein Ib alpha by valine mutagenesis in the Cys(209)-Cys(24)8 disulfide loop
JOURNAL OF BIOLOGICAL CHEMISTRY
Signaling across the platelet adhesion receptor glycoprotein Ib-IX inducesalpha(IIb)beta(3) activation both in platelets and a transfected Chinese hamster ovary cell system
JOURNAL OF BIOLOGICAL CHEMISTRY
Modeling and functional analysis of the interaction between von Willebrandfactor A1 domain and glycoprotein Ib alpha
JOURNAL OF BIOLOGICAL CHEMISTRY
Localization of von Willebrand factor-binding sites for platelet glycoprotein Ib and botrocetin by charged-to-alanine scanning mutagenesis
JOURNAL OF BIOLOGICAL CHEMISTRY
Inhibitory effect of various thrombin inhibitors on shear-induced plateletfunction and dynamic coagulation
EUROPEAN JOURNAL OF PHARMACOLOGY
Porcine von Willebrand factor and thrombin induce the activation of c-Jun amino-terminal kinase (JNK/SAPK) whereas only thrombin induces activation of extracellular signal-related kinase 2 (ERK2) in human platelets
BRITISH JOURNAL OF HAEMATOLOGY
Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3 zeta
BLOOD
Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies
BLOOD
Requirement of leucine-rich repeats of glycoprotein (GP) Ib alpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex
BLOOD
Effect of recombinant von Willebrand factor reproducing type 2B or type 2Mmutations on shear-induced platelet aggregation
BLOOD
Targeting of liposomes carrying recombinant fragments of platelet membraneglycoprotein Ib alpha to immobilized von Willebrand factor under flow conditions
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Thrombin interaction with platelet GpIb: Structural mapping and effects onplatelet activation (Review)
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
von Willebrand factor: from cell biology to the clinical management of vonWillebrand's disease
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
A shear-induced in vitro platelet function test can assess clinically relevant anti-thrombotic effects
PLATELETS
Shear-dependent functions of the interaction between soluble von Willebrand factor and platelet glycoprotein Ib in mural thrombus formation on a collagen surface
INTERNATIONAL JOURNAL OF HEMATOLOGY
Cloning and expression of canine glycoprotein Ib alpha
THROMBOSIS AND HAEMOSTASIS
Effects of clopidogrel on platelet activation and coagulation of non-anticoagulated rat blood under high shear stress
HAEMOSTASIS
Adhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ib alpha in a flow field
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model
JOURNAL OF CELL BIOLOGY
The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of domains responsible for von Willebrand factor type VI collagen interaction mediating platelet adhesion under high flow
JOURNAL OF BIOLOGICAL CHEMISTRY
Distinct structural attributes regulating von Willebrand factor A1 domain interaction with platelet glycoprotein Ib alpha under flow
JOURNAL OF BIOLOGICAL CHEMISTRY
Thrombin-induced platelet activation is inhibited by high- and low-molecular-weight heparin
CIRCULATION
Influence of fibrillar collagen structure on the mechanisms of platelet thrombus formation under flow
BLOOD
Glycoprotein Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor gamma-chain, Fyn, and Lyn to activate human platelets
BLOOD
Cytosolic calcium changes in a process of platelet adhesion and cohesion on a von Willebrand factor-coated surface under flow conditions
BLOOD
Real-time analysis of mural thrombus formation in various platelet aggregation disorders: Distinct shear-dependent roles of platelet receptors and adhesive proteins under flow
BLOOD
Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and do not exhibit a Bernard-Soulier phenotype
BLOOD
Contribution of distinct adhesive interactions to platelet aggregation in flowing blood
BLOOD
Marked temperature dependence of the platelet calcium signal induced by human von Willebrand factor
BLOOD
Interaction between GPIb alpha and Fc gamma IIA receptor in human platelets
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib alpha: A potential substitute for platelet transfusion
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Platelet adhesion receptors: novel targets for anti-thrombotic therapy
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE
WHAT HAVE SNAKES TAUGHT US ABOUT INTEGRINS
Cellular and molecular life sciences
ANTI-GLYCOPROTEIN IB CAUSES PLATELET-AGGREGATION - DIFFERENT EFFECTS OF BLOCKING GLYCOPROTEIN IB AND GLYCOPROTEIN IIB IIIA IN THE HIGH-SHEAR FILTEROMETER/
Blood coagulation & fibrinolysis
RISTOCETIN-INDUCED AND THROMBIN-INDUCED PLATELET-AGGREGATION AT PHYSIOLOGICAL SHEAR RATES - DIFFERENTIAL ROLES FOR GPIB AND GPIIB-IIIA RECEPTOR
Thrombosis and haemostasis
MOLECULAR ANALYSES OF THE PLATELET GLYCOPROTEIN IB-IX-V RECEPTOR
Thrombosis and haemostasis
BIOMECHANICS OF CELL-INTERACTIONS IN SHEAR FIELDS
Advanced drug delivery reviews
SPECIFIC SYNERGY OF MULTIPLE SUBSTRATE-RECEPTOR INTERACTIONS IN PLATELET THROMBUS FORMATION UNDER FLOW
Cell (Cambridge)
RISTOCETIN-MEDIATED INTERACTION OF HUMAN VON-WILLEBRAND-FACTOR WITH PLATELET GLYCOPROTEIN IB EVOKES A TRANSIENT CALCIUM SIGNAL - OBSERVATIONS WITH FURA-PE3
The Journal of laboratory and clinical medicine
DISTINCT MECHANISMS OF PLATELET-AGGREGATION AS A CONSEQUENCE OF DIFFERENT SHEARING FLOW CONDITIONS
The Journal of clinical investigation
CHARACTERIZATION OF THE INITIAL ALPHA-THROMBIN INTERACTION WITH GLYCOPROTEIN IB-ALPHA IN RELATION TO PLATELET ACTIVATION
The Journal of biological chemistry
A novel ligand-binding site in the zeta-form 14-3-3 protein recognizing the platelet glycoprotein Ib alpha and distinct from the c-Raf-binding site
JOURNAL OF BIOLOGICAL CHEMISTRY
CORONARY-THROMBOSIS - EFFECTS OF BLOOD-FLOW ON THE MECHANISM OF THROMBUS FORMATION
Japanese Heart Journal
POLYMORPHISMS OF PLATELET MEMBRANE GLYCOPROTEIN IB-ALPHA ASSOCIATED WITH ARTERIAL THROMBOTIC DISEASE
Blood
NATURALLY-OCCURRING MUTATIONS IN GLYCOPROTEIN IB-ALPHA THAT RESULT INDEFECTIVE LIGAND-BINDING AND SYNTHESIS OF A TRUNCATED PROTEIN
Blood
MOLECULAR MODELING OF LIGAND AND MUTATION SITES OF THE TYPE-A DOMAINSOF HUMAN VON-WILLEBRAND-FACTOR AND THEIR RELEVANCE TO VON-WILLEBRANDS-DISEASE
Blood
TYPE 2M VON-WILLEBRAND-DISEASE - F606I AND I662F MUTATIONS IN THE GLYCOPROTEIN IB BINDING DOMAIN SELECTIVELY IMPAIR RISTOCETIN - BUT NOT BOTROCETIN-MEDIATED BINDING OF VON-WILLEBRAND-FACTOR TO PLATELETS
Blood
ANTITHROMBOTIC EFFECT OF CROTALIN, A PLATELET MEMBRANE GLYCOPROTEIN IB ANTAGONIST FROM VENOM OF CROTALUS-ATROX
Blood
BERNARD-SOULIER-SYNDROME
Blood
BINDING OF PURIFIED 14-3-3-ZETA SIGNALING PROTEIN TO DISCRETE AMINO-ACID-SEQUENCES WITHIN THE CYTOPLASMIC DOMAIN OF THE PLATELET MEMBRANE GLYCOPROTEIN IB-IX-V COMPLEX
Biochemistry
PLATELET-AGGREGATION INDUCED BY A MONOCLONAL-ANTIBODY TO THE A1 DOMAIN OF VON-WILLEBRAND-FACTOR
Blood
PLATELET-AGGREGATION IN FLOW - DIFFERENTIAL ROLES FOR ADHESIVE RECEPTORS AND LIGANDS
The American heart journal
BLOOD-FLOW AND ANTITHROMBOTIC DRUG EFFECTS
The American heart journal
MOLECULAR MECHANISMS OF PLATELET-ADHESION AND ACTIVATION
International journal of biochemistry & cell biology
CRYSTAL-STRUCTURE OF NMC-4 FAB ANTI-VON WILLEBRAND FACTOR A1 DOMAIN
Blood cells, molecules, & diseases
CLONING OF THE MURINE PLATELET GLYCOPROTEIN IB-ALPHA GENE HIGHLIGHTING SPECIES-SPECIFIC PLATELET-ADHESION
Blood cells, molecules, & diseases
PLATELET ACTIVATION IN FLOWING BLOOD PASSING GROWING ARTERIAL THROMBI
Arteriosclerosis, thrombosis, and vascular biology
RELATIVE INVOLVEMENT OF GPIB IX-VWF AXIS AND GPIIB/IIIA IN THROMBUS GROWTH AT HIGH-SHEAR RATES IN THE GUINEA-PIG/
Arteriosclerosis, thrombosis, and vascular biology
VEIN GRAFTS - HEMODYNAMIC FORCES ON THE ENDOTHELIUM - A REVIEW
European journal of vascular and endovascular surgery
THE BIOLOGICAL-ACTIVITIES OF DISINTEGRINS AND THEIR POSSIBLE APPLICATIONS
Journal of toxicology. Toxin reviews
CALPAIN ACTIVATION IN SHEAR-INDUCED PLATELET-AGGREGATION
Journal of cellular biochemistry
RATIOMETRIC MEASUREMENTS WITH FLUORESCENT INDICATORS SHOULD BE INTERPRETED CAUTIOUSLY IN STUDIES OF PLATELET CALCIUM SIGNALING FOR VON-WILLEBRAND-FACTOR
Thrombosis and haemostasis
EFFECT OF A NEW MONOCLONAL ANTI-GLYCOPROTEIN-IX ANTIBODY, KMP-9, ON HIGH-SHEAR INDUCED PLATELET-AGGREGATION
Thrombosis and haemostasis
PLATELET GPIB-V-IX COMPLEX
Thrombosis and haemostasis
THE SIGNIFICANCE OF SUBENDOTHELIAL VON-WILLEBRAND-FACTOR
Thrombosis and haemostasis
MECHANISMS INITIATING PLATELET THROMBUS FORMATION
Thrombosis and haemostasis
MOLECULAR AND GENETIC-ANALYSIS OF 2 PATIENTS WITH BERNARD-SOULIER-SYNDROME - IDENTIFICATION OF NEW MUTATIONS IN GLYCOPROTEIN IB-ALPHA GENE
Thrombosis and haemostasis
DEFECTIVE INTERACTION BETWEEN VON-WILLEBRAND-FACTOR AND PLATELET GLYCOPROTEIN IB - A FAMILIAL STUDY OF PERIPHERAL ARTERIAL OCCLUSIVE DISEASE
Thrombosis and haemostasis
VON-WILLEBRAND-FACTOR BINDS TO NATIVE COLLAGEN-VI PRIMARILY VIA ITS A1 DOMAIN
Biochemical journal