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Phenotypic and dynamical transitions in model genetic networks I. Emergence of patterns and genotype-phenotype relationships
EVOLUTION & DEVELOPMENT
A comparative molecular analysis of developing mouse forelimbs and hindlimbs using Serial Analysis of Gene Expression (SAGE)
GENOME RESEARCH
The molecular genetics of inherited cartilage disease
OSTEOARTHRITIS AND CARTILAGE
Differential response of Shh expression between chick forelimb and hindlimb buds by FGF-4
DEVELOPMENTAL DYNAMICS
Expression patterns of Fgf-8 during development and limb regeneration of the axolotl
DEVELOPMENTAL DYNAMICS
Characterisation of Hoxa gene expression in the chick limb bud in responseto FGF
DEVELOPMENTAL DYNAMICS
Regulatory mechanisms in the pathways of cartilage and bone formation
CURRENT OPINION IN CELL BIOLOGY
BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb
DEVELOPMENT
Unique functions of Sonic hedgehog signaling during external genitalia development
DEVELOPMENT
msh specifies dorsal cell fate in the Drosophila wing
DEVELOPMENT
Evidence for a role of protein kinase C in FGF signal transduction in the developing chick limb bud
DEVELOPMENT
LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem
MECHANISMS OF DEVELOPMENT
Differential expression of two BMP antagonists, gremlin and Follistatin, during development of the chick feather bud
MECHANISMS OF DEVELOPMENT
Some distal limb structures develop in mice lacking Sonic hedgehog signaling
MECHANISMS OF DEVELOPMENT
Constitutive expression of FGF4 disrupts the development of the eye and the anterior CNS during mouse embryogenesis, but does not influence the expression of shh in these areas
BELGIAN JOURNAL OF ZOOLOGY
The molecular control of upper extremity development: Implications for congenital hand anomalies
JOURNAL OF HAND SURGERY-AMERICAN VOLUME
Developmental expression of chick Twist and its regulation during limb patterning
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
Why five fingers? Evolutionary constraints on digit numbers
TRENDS IN ECOLOGY & EVOLUTION
How molecular is molecular developmental biology? A reply to Alex Rosenberg's reductionism redux: Computing the embryo
BIOLOGY & PHILOSOPHY
Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1
CELL
WNT signals control FGF-dependent limb initiation and AER induction in thechick embryo
CELL
Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton
CELL
A physical force may expose Hox genes to express in a morphogenetic density gradient
BULLETIN OF MATHEMATICAL BIOLOGY
Cell biology of limb patterning
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 203
Differential expression of fibroblast growth factor receptors in human digital development suggests common pathogenesis in complex acrosyndactyly andcraniosynostosis
PLASTIC AND RECONSTRUCTIVE SURGERY
Using heterochrony plots to detect the dissociated coevolution of characters
JOURNAL OF EXPERIMENTAL ZOOLOGY
Retinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopod
JOURNAL OF ANATOMY
Ptc1 and Ptc2 transcripts provide distinct readouts of hedgehog signaling activity during chick embryogenesis
DEVELOPMENTAL BIOLOGY
The FGFR pathway is required for the trunk-inducing functions of Spemann'sorganizer
DEVELOPMENTAL BIOLOGY
Manifestation of the limb prepattern: Limb development in the absence of sonic hedgehog function
DEVELOPMENTAL BIOLOGY
Identification and characterization of Lbh, a novel conserved nuclear protein expressed during early limb and heart development
DEVELOPMENTAL BIOLOGY
Agenesis of the scapula in Emx2 homozygous mutants
DEVELOPMENTAL BIOLOGY
Nerve-independence of limb regeneration in larval Xenopus laevis is correlated to the level of fgf-2 mRNA expression in limb tissues
DEVELOPMENTAL BIOLOGY
Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 andis required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4
DEVELOPMENTAL BIOLOGY
An epidermal signal regulates Lmx-1 expression and dorsal-ventral pattern during Xenopus limb regeneration
DEVELOPMENTAL BIOLOGY
Fibroblast growth factor-induced gene expression and cartilage pattern formation in chick limb bud recombinants
DEVELOPMENT GROWTH & DIFFERENTIATION
Polymelia in the tadpoles of Bufo melanostictus (Anura : Bufonidae)
CURRENT SCIENCE
Distal limb malformations: underlying mechanisms and clinical associations
CLINICAL GENETICS
Split hand/split foot malformation with hearing loss: first report of families linked to the SHFM1 locus in 7q21
CLINICAL GENETICS
Limbs and tail as evolutionarily diverging duplicates of the main body axis
EVOLUTION & DEVELOPMENT
Human breast development
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
Fgf8 is required for outgrowth and patterning of the limbs
NATURE GENETICS
Fgf8 signalling from the AER is essential for normal limb development
NATURE GENETICS
Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development
NATURE GENETICS
The SH2 tyrosine phosphatase Shp2 is required for mammalian limb development
NATURE GENETICS
Forkhead transcription factor FoxF2 is expressed in mesodermal tissues involved in epithelio-mesenchymal interactions
DEVELOPMENTAL DYNAMICS
Apical epithelial cap morphology and fibronectin gene expression in regenerating axolot1 limbs
DEVELOPMENTAL DYNAMICS
Differential display of genes expressed at the midbrain-hindbrain junctionidentifies sprouty2: An FGF8-inducible member of a family of intracellularFGF antagonists
MOLECULAR AND CELLULAR NEUROSCIENCE
LMX1B transactivation and expression in nail-patella syndrome
HUMAN MOLECULAR GENETICS
Constructive antagonism in limb development
CURRENT OPINION IN GENETICS & DEVELOPMENT
The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium
DEVELOPMENT
A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehogexpression in the mouse tooth germ
DEVELOPMENT
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
DEVELOPMENT
Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity
DEVELOPMENT
Apterous mediates development of direct flight muscles autonomously and indirect flight muscles through epidermal cues
DEVELOPMENT
Evidence that members of the Cut/Cux/CDP family may be involved in AER positioning and polarizing activity during chick limb development
DEVELOPMENT
Autoregulation of Shh expression and Shh induction of cell death suggest amechanism for modulating polarising activity during chick limb development
DEVELOPMENT
dackel acts in the ectoderm of the zebrafish pectoral fin bud to maintain AER signaling
DEVELOPMENT
Distribution of polarizing activity and potential for limb formation in mouse and chick embryos and possible relationships to polydactyly
DEVELOPMENT
Dual roles of Wnt signaling during chondrogenesis in the chicken limb
DEVELOPMENT
The bHLH transcription factor dHAND controls Sonic hedgehog expression andestablishment of the zone of polarizing activity during limb development
DEVELOPMENT
Molecular analysis of external genitalia formation: the role of fibroblastgrowth factor (Fgf) genes during genital tubercle formation
DEVELOPMENT
Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway
DEVELOPMENT
Expression and regulation of chicken fibroblast growth factor homologous factor (FHF)-4 at the base of the developing limbs
MECHANISMS OF DEVELOPMENT
FGF and genes encoding transcription factors in early limb specification
MECHANISMS OF DEVELOPMENT
Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling
MECHANISMS OF DEVELOPMENT
Pattern formation and regulation of gene expressions in chick recombinant limbs
MECHANISMS OF DEVELOPMENT
Genomic organization, sequence and chromosomal localization of the mouse Tbr2 gene and a comparative study with Tbr1
GENE
SOX14 is a candidate gene for limb defects associated with BPES and Mobiussyndrome
HUMAN GENETICS
Functions of LIM-homeobox genes
TRENDS IN GENETICS
Fossils, genes, and the origin of novelty
PALEOBIOLOGY
Hind limb malformations in free-living northern leopard frogs (Rana pipiens) from Maine, Minnesota, and Vermont suggest multiple etiologies
TERATOLOGY
Fingering digit identity
SCIENCE
Feedback control of intercellular signalling in development
NATURE
Perspectives on the evolutionary origin of tetrapod limbs
JOURNAL OF EXPERIMENTAL ZOOLOGY
Epigenetic mechanisms of character origination
JOURNAL OF EXPERIMENTAL ZOOLOGY
P68, a DEAD-Box RNA helicase, is expressed in chordate embryo neural and mesodermal tissues
JOURNAL OF EXPERIMENTAL ZOOLOGY
Mesenchymal expression of nuclear factor-kappa B inhibits epithelial growth and branching in the embryonic chick lung
DEVELOPMENTAL BIOLOGY
Activation of Fgf4 gene expression in the myotomes is regulated by myogenic bHLH factors and by sonic hedgehog
DEVELOPMENTAL BIOLOGY
csal1 is controlled by a combination of FGF and Wnt signals in developing limb buds
DEVELOPMENTAL BIOLOGY
Engrailed-1 misexpression in chick embryos prevents apical ridge formationbut preserves segregation of dorsal and ventral ectodermal compartments
DEVELOPMENTAL BIOLOGY
Roles for Fgf signaling during zebrafish fin regeneration
DEVELOPMENTAL BIOLOGY
Targeted misexpression of constitutively active BMP receptor-IB causes bifurcation, duplication, and posterior transformation of digit in mouse limb
DEVELOPMENTAL BIOLOGY
Influence of FGF4 on digit morphogenesis during limb development in the mouse
DEVELOPMENTAL BIOLOGY
Severe limb defects in Hypodactyly mice result from the expression of a novel, mutant HOXA13 protein
DEVELOPMENTAL BIOLOGY
Involvement of Frizzled-10 in Wnt-7a signaling during chick limb development
DEVELOPMENT GROWTH & DIFFERENTIATION
Suppression of polydactyly of the Gli3 mutant (extra toes) by delta EF1 homozygous mutation
DEVELOPMENT GROWTH & DIFFERENTIATION
Synergistic effects of FGF and non-ridge ectoderm on gene expression involved in the formation of the anteroposterior axis of the chick limb bud in cell culture
DEVELOPMENT GROWTH & DIFFERENTIATION
Characterization of a novel member of the FGFR family, HrFGFR, in Halocynthia roretzi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Notch signaling is not sufficient to define the affinity boundary between dorsal and ventral compartments
MOLECULAR CELL
Morphogen gradients in vertebrate limb development
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
RLIM inhibits functional activity of LIM homeodomain transcription factorsvia recruitment of the histone deacetylase complex
NATURE GENETICS
Fgf10 is essential for limb and lung formation
NATURE GENETICS
Dlx-5 in limb initiation in the chick embryo
DEVELOPMENTAL DYNAMICS
The developmental control of osteoblast-specific gene expression: Role of specific transcription factors and the extracellular matrix environment
CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE
Restoring avian wing digits
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
The developmental basis for allometry in insects
DEVELOPMENT
BMPs negatively regulate structure and function of the limb apical ectodermal ridge
DEVELOPMENT
Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
DEVELOPMENT
The dominant hemimelia mutation uncouples epithelial-mesenchymal interactions and disrupts anterior mesenchyme formation in mouse hindlimbs
DEVELOPMENT