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La ricerca find articoli where soggetti phrase all words 'TURTLE RETINA' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 128 riferimenti
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    1. Sernagor, E; Eglen, SJ; Wong, OL
      Development of retinal ganglion cell structure and function

      PROGRESS IN RETINAL AND EYE RESEARCH
    2. Andreu, E; Fernandez, E; Louis, E; Ortega, G; Sanchez-Andres, JV
      On the validity of the two-cells model in the analysis of passive electrical properties of gap-junction connected cells

      EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
    3. Kamermans, M; Kraaij, D; Spekreijse, H
      The dynamic characteristics of the feedback signal from horizontal cells to cones in the goldfish retina

      JOURNAL OF PHYSIOLOGY-LONDON
    4. Reckel, F; Melzer, RR; Smola, U
      Outer retinal fine structure of the garfish Belone belone (L.) (Belonidae,Teleostei) during light and dark adaptation - photoreceptors, cone patterns and densities

      ACTA ZOOLOGICA
    5. Xin, DY; Bloomfield, SA
      Effects of nitric oxide on horizontal cells in the rabbit retina

      VISUAL NEUROSCIENCE
    6. Blute, TA; Lee, MR; Eldred, WD
      Direct imaging of NMDA-stimulated nitric oxide production in the retina

      VISUAL NEUROSCIENCE
    7. Cao, LX; Blute, TA; Eldred, WD
      Localization of heme oxygenase-2 and modulation of cGMP levels by carbon monoxide and/or nitric oxide in the retina

      VISUAL NEUROSCIENCE
    8. Rauen, T
      Diversity of glutamate transporter expression and function in the mammalian retina

      AMINO ACIDS
    9. Roska, B; Nemeth, E; Orzo, L; Werblin, FS
      Three levels of lateral inhibition: A space-time study of the retina of the tiger salamander

      JOURNAL OF NEUROSCIENCE
    10. Weiler, R; Pottek, M; He, SG; Vaney, DI
      Modulation of coupling between retinal horizontal cells by retinoic acid and endogenous dopamine

      BRAIN RESEARCH REVIEWS
    11. Okada, T; Weiler, R
      Multirecording of Ca2+ signals from inner retinal neurons evoked by light stimulation of photoreceptors

      VISION RESEARCH
    12. Andreu, E; Fernandez, E; Louis, E; Ortega, G; Sanchez-Andres, JV
      Role of architecture in determining passive electrical properties in gap junction-connected cells

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    13. Feigenspan, A; Gustincich, S; Raviola, E
      Pharmacology of GABA(A) receptors of retinal dopaminergic neurons

      JOURNAL OF NEUROPHYSIOLOGY
    14. Kraaij, DA; Spekreijse, H; Kamermans, M
      The open- and closed-loop gain-characteristics of the cone/horizontal cellsynapse in goldfish retina

      JOURNAL OF NEUROPHYSIOLOGY
    15. Kraaij, DA; Spekreijse, H; Kamermans, M
      The nature of surround-induced depolarizing responses in goldfish cones

      JOURNAL OF GENERAL PHYSIOLOGY
    16. Blute, TA; Lee, HK; Huffmaster, T; Haverkamp, S; Eldred, WD
      Localization of natriuretic peptides and their activation of particulate guanylate cyclase and nitric oxide synthase in the retina

      JOURNAL OF COMPARATIVE NEUROLOGY
    17. PICCOLINO M; PIGNATELLI A; RAKOTOBE LA
      CALCIUM-INDEPENDENT RELEASE OF NEUROTRANSMITTER IN THE RETINA - A COPERNICAN VIEWPOINT CHANGE

      Progress in retinal and eye research
    18. White, TW; Deans, MR; O'Brien, J; Al-Ubaidi, MR; Goodenough, DA; Ripps, H; Bruzzone, R
      Functional characteristics of skate connexin35, a member of the gamma subfamily of connexins expressed in the vertebrate retina

      EUROPEAN JOURNAL OF NEUROSCIENCE
    19. Lei, B; Perlman, I
      The contributions of voltage- and time-dependent potassium conductances tothe electroretinogram in rabbits

      VISUAL NEUROSCIENCE
    20. Ventura, DF; de Souza, JM; Devoe, RD; Zana, Y
      UV responses in the retina of the turtle

      VISUAL NEUROSCIENCE
    21. Taylor, WR
      TTX attenuates surround inhibition in rabbit retinal ganglion cells

      VISUAL NEUROSCIENCE
    22. Granda, AM; Dearworth, JR; Subramaniam, B
      Balanced interactions in ganglion-cell receptive fields

      VISUAL NEUROSCIENCE
    23. Vigh, J; Witkovsky, P
      Sub-millimolar cobalt selectively inhibits the receptive field surround ofretinal neurons

      VISUAL NEUROSCIENCE
    24. Schneeweis, DM; Schnapf, JL
      The photovoltage of macaque cone photoreceptors: Adaptation, noise, and kinetics

      JOURNAL OF NEUROSCIENCE
    25. Gustincich, S; Feigenspan, A; Sieghart, W; Raviola, E
      Composition of the GABA(A) receptors of retinal dopaminergic neurons

      JOURNAL OF NEUROSCIENCE
    26. Dmitriev, A; Pignatelli, A; Piccolino, M
      Resistance of retinal extracellular space to Ca2+ level decrease: Implications for the synaptic effects of divalent cations

      JOURNAL OF NEUROPHYSIOLOGY
    27. Fahrenfort, I; Habets, RL; Spekreijse, H; Kamermans, M
      Intrinsic cone adaptation modulates feedback efficiency from horizontal cells to cones

      JOURNAL OF GENERAL PHYSIOLOGY
    28. Reckel, F; Melzer, RR; Smola, U
      Ultrastructure of the retina of two subspecies of Coregonus lavaretus (Teleostei) from Lake Constance (Germany)

      ACTA ZOOLOGICA
    29. BALDRIDGE WH; VANEY DI; WEILER R
      THE MODULATION OF INTERCELLULAR COUPLING IN THE RETINA

      Seminars in cell & developmental biology
    30. KAMERMANS M; KRAAIJ DA; SPEKREIJSE H
      THE CONE HORIZONTAL CELL NETWORK - A POSSIBLE SITE FOR COLOR CONSTANCY/

      Visual neuroscience
    31. KRAAIJ DA; KAMERMANS M; SPEKREIJSE H
      SPECTRAL SENSITIVITY OF THE FEEDBACK SIGNAL FROM HORIZONTAL CELLS TO CONES IN GOLDFISH RETINA

      Visual neuroscience
    32. TAYLOR WR; MORGANS C
      LOCALIZATION AND PROPERTIES OF VOLTAGE-GATED CALCIUM CHANNELS IN CONEPHOTORECEPTORS OF TUPAIA-BELANGERI

      Visual neuroscience
    33. BOELEN MK; BOELEN MG; MARSHAK DW
      LIGHT-STIMULATED RELEASE OF DOPAMINE FROM THE PRIMATE RETINA IS BLOCKED BY L-2-AMINO-4-PHOSPHONOBUTYRIC ACID (APB)

      Visual neuroscience
    34. PEPPE A; ANTAL A; TAGLIATI M; STANZIONE P; BODISWOLLNER I
      D1 AGONIST CY208-243 ATTENUATES THE PATTERN ELECTRORETINOGRAM TO LOW SPATIAL-FREQUENCY STIMULI IN THE MONKEY

      Neuroscience letters
    35. BURGI PY; GRZYWACZ NM
      A BIOPHYSICAL MODEL FOR THE DEVELOPMENTAL TIME-COURSE OF RETINAL ORIENTATION SELECTIVITY

      Vision research (Oxford)
    36. HSU A; TSUKAMOTO Y; SMITH RG; STERLING P
      FUNCTIONAL ARCHITECTURE OF PRIMATE CONE AND ROD AXONS

      Vision research (Oxford)
    37. WEILER R; SCHULTZ K; POTTEK M; TIEDING S; JANSSENBIENHOLD U
      RETINOIC ACID HAS LIGHT-ADAPTIVE EFFECTS ON HORIZONTAL CELLS IN THE RETINA

      Proceedings of the National Academy of Sciences of the United Statesof America
    38. KRIZAJ D; GABRIEL R; OWEN WG; WITKOVSKY P
      DOPAMINE D2 RECEPTOR-MEDIATED MODULATION OF ROD-CONE COUPLING IN THE XENOPUS RETINA

      Journal of comparative neurology
    39. BALL AK; MCREYNOLDS JS
      LOCALIZATION OF GAP-JUNCTIONS AND TRACER COUPLING IN RETINAL MULLER CELLS

      Journal of comparative neurology
    40. CHIBA C
      APPEARANCE OF GLUTAMATE-LIKE IMMUNOREACTIVITY DURING RETINAL REGENERATION IN THE ADULT NEWT

      Brain research
    41. ZHU BS; GIBBINS IL
      SYNAPTIC INPUTS TO RETROGRADELY LABELED GANGLION-CELLS IN THE RETINA OF THE CANE TOAD, BUFO-MARINUS

      Visual neuroscience
    42. WEILER R; BALDRIDGE WH; MANGEL SC; DOWLING JE
      MODULATION OF ENDOGENOUS DOPAMINE RELEASE IN THE FISH RETINA BY LIGHTAND PROLONGED DARKNESS

      Visual neuroscience
    43. GRZYWACZ NM; TOOTLE JS; AMTHOR FR
      IS THE INPUT TO A GABAERGIC OR CHOLINERGIC SYNAPSE THE SOLE ASYMMETRYIN RABBITS RETINAL DIRECTIONAL SELECTIVITY

      Visual neuroscience
    44. GUSTINCICH S; FEIGENSPAN A; WU DK; KOOPMAN LJ; RAVIOLA E
      CONTROL OF DOPAMINE RELEASE IN THE RETINA - A TRANSGENIC APPROACH TO NEURAL NETWORKS

      Neuron
    45. POTTEK M; SCHULTZ K; WEILER R
      EFFECTS OF NITRIC-OXIDE ON THE HORIZONTAL CELL NETWORK AND DOPAMINE RELEASE IN THE CARP RETINA

      Vision research
    46. HAUG BA; HERMSTEINER EM; BANDELOW B; PAULUS W
      PARALLEL INCREASE OF HETEROCHROMATIC INCREMENT THRESHOLD AND POSTADAPTATION THRESHOLDS IN PARKINSONS-DISEASE IN NEUROLEPTIC TREATMENT

      Vision research
    47. SAVCHENKO A; BARNES S; KRAMER RH
      CYCLIC-NUCLEOTIDE-GATED CHANNELS MEDIATE SYNAPTIC FEEDBACK BY NITRIC-OXIDE

      Nature
    48. WANG Y; HARSANYI K; MANGEL SC
      ENDOGENOUS ACTIVATION OF DOPAMINE D2 RECEPTORS REGULATES DOPAMINE RELEASE IN THE FISH RETINA

      Journal of neurophysiology
    49. YANG CY
      L-GLUTAMIC ACID DECARBOXYLASE-IMMUNOREACTIVE AND GAMMA-AMINOBUTYRIC ACID-IMMUNOREACTIVE BIPOLAR CELLS IN TIGER SALAMANDER RETINA ARE OF ON-RESPONSE AND OFF-RESPONSE TYPES AS INFERRED FROM LUCIFER YELLOW INJECTION

      Journal of comparative neurology
    50. KAWAI F; KAMIYAMA Y; USUI S
      DESENSITIZATION OF THE GABA(A) RECEPTOR SHIFTS THE DYNAMIC-RANGE OF RETINAL HORIZONTAL CELLS DUE TO LIGHT AND DARK-ADAPTATION

      Japanese Journal of Physiology
    51. AKOPIAN A; KRIZAJ D; WITKOVSKY P
      BOTH HIGH-VOLTAGE-ACTIVATED AND LOW-VOLTAGE-ACTIVATED CALCIUM CURRENTS CONTRIBUTE TO THE LIGHT-EVOKED RESPONSES OF LUMINOSITY HORIZONTAL CELLS IN THE XENOPUS RETINA

      Brain research
    52. PICCOLINO M; PIGNATELLI A; SBRENNA L
      RETINAL HORIZONTAL CELLS - OLD CELLS, OLD EXPERIMENTS, NEW RESULTS

      Archives Italiennes de Biologie
    53. VITANOVA L; KUPENOVA P; POPOVA E; MITOVA L
      INFLUENCE OF PICROTOXIN AND STRYCHNINE ON THE SPECTRAL SENSITIVITY OFTHE TURTLE ERG B-WAVE AND D-WAVE .2. LIGHT ADAPTATION

      Acta Physiologica Scandinavica
    54. OBRIEN J; ALUBAIDI MR; RIPPS H
      CONNEXIN-35 - A GAP-JUNCTIONAL PROTEIN EXPRESSED PREFERENTIALLY IN THE SKATE RETINA

      Molecular biology of the cell
    55. ZEMEL E; EYAL O; LEI B; PERLMAN I
      NADPH DIAPHORASE ACTIVITY IN MAMMALIAN RETINAS IS MODULATED BY THE STATE OF VISUAL-ADAPTATION

      Visual neuroscience
    56. AKOPIAN A; WITKOVSKY P
      ACTIVATION OF METABOTROPIC GLUTAMATE RECEPTORS DECREASES A HIGH-THRESHOLD CALCIUM CURRENT IN SPIKING NEURONS OF THE XENOPUS RETINA

      Visual neuroscience
    57. LAUFER M; NEGISHI K; SALAS R
      EFFECTS OF GLUTAMIC-ACID AND RELATED AGENTS ON HORIZONTAL CELLS IN A MARINE TELEOST RETINA

      Journal of neuroscience research
    58. RAUEN T; ROTHSTEIN JD; WASSLE H
      DIFFERENTIAL EXPRESSION OF 3 GLUTAMATE TRANSPORTER SUBTYPES IN THE RAT RETINA

      Cell and tissue research
    59. YANG CY
      GLUTAMATE IMMUNOREACTIVITY IN THE TIGER SALAMANDER RETINA DIFFERENTIATES BETWEEN GABA-IMMUNOREACTIVE AND GLYCINE-IMMUNOREACTIVE AMACRINE CELLS

      Journal of neurocytology
    60. SCHLEMERMEYER E; CHAPPELL RL
      2 CLASSES OF BIPOLAR CELL IN THE RETINA OF THE SKATE RAJA-ERINACEA

      Journal of neurocytology
    61. SCHMITZ F; BECHMANN M; DRENCKHAHN D
      PURIFICATION OF SYNAPTIC RIBBONS, STRUCTURAL COMPONENTS OF THE PHOTORECEPTOR ACTIVE ZONE COMPLEX

      The Journal of neuroscience
    62. SCHMITZ Y; WITKOVSKY P
      GLUTAMATE RELEASE BY THE INTACT LIGHT-RESPONSIVE PHOTORECEPTOR LAYER OF THE XENOPUS RETINA

      Journal of neuroscience methods
    63. VERWEIJ J; KAMERMANS M; VANDENAKER EC; SPEKREIJSE H
      MODULATION OF HORIZONTAL CELL RECEPTIVE-FIELDS IN THE LIGHT-ADAPTED GOLDFISH RETINA

      Vision research
    64. DIXON DB; TAKAHASHI KI; BIEDA M; COPENHAGEN DR
      QUININE, INTRACELLULAR PH AND MODULATION OF HEMI-GAP JUNCTIONS IN CATFISH HORIZONTAL CELLS

      Vision research
    65. VERWEIJ J; KAMERMANS M; SPEKREIJSE H
      HORIZONTAL CELLS FEED BACK TO CONES BY SHIFTING THE CONE CALCIUM-CURRENT ACTIVATION RANGE

      Vision research
    66. VANDEGRIND WA; LANKHEET MJM; VANWEZEL RJA; ROWE MH; HULLEMAN J
      GAIN-CONTROL AND HYPERPOLARIZATION LEVEL IN CAT HORIZONTAL CELLS AS AFUNCTION OF LIGHT AND DARK-ADAPTATION

      Vision research
    67. MAPLE BR; WU SM
      SYNAPTIC INPUTS MEDIATING BIPOLAR CELL RESPONSES IN THE TIGER SALAMANDER RETINA

      Vision research
    68. USUI S; KAMIYAMA Y; ISHII H; IKENO H
      RECONSTRUCTION OF RETINAL HORIZONTAL CELL RESPONSES BY THE IONIC CURRENT MODEL

      Vision research
    69. LANUZA E; MARTINEZMARCOS A; FONT C; MARTINEZGARCIA F
      CATECHOLAMINERGIC INTERPLEXIFORM CELLS IN THE RETINA OF LIZARDS

      Vision research
    70. YANG XL; WU SM
      RESPONSE SENSITIVITY AND VOLTAGE GAIN OF THE ROD-CELL AND CONE-CELL HORIZONTAL CELL SYNAPSES IN DARK-ADAPTED AND LIGHT-ADAPTED TIGER SALAMANDER RETINA

      Journal of neurophysiology
    71. HARE WA; OWEN WG
      RECEPTIVE-FIELD OF THE RETINAL BIPOLAR CELL - A PHARMACOLOGICAL STUDYIN THE TIGER SALAMANDER

      Journal of neurophysiology
    72. BLOOMFIELD SA
      EFFECT OF SPIKE BLOCKADE ON THE RECEPTIVE-FIELD SIZE OF AMACRINE AND GANGLION-CELLS IN THE RABBIT RETINA

      Journal of neurophysiology
    73. HARSANYI K; WANG Y; MANGEL SC
      ACTIVATION OF NMDA RECEPTORS PRODUCES DOPAMINE-MEDIATED CHANGES IN FISH RETINAL HORIZONTAL CELL LIGHT RESPONSES

      Journal of neurophysiology
    74. MIZUNAMI M
      GAIN-CONTROL OF SYNAPTIC TRANSFER FROM 2ND-ORDER TO 3RD-ORDER NEURONSOF COCKROACH OCELLI

      The Journal of general physiology
    75. PICCOLINO M
      THE FEEDBACK SYNAPSE FROM HORIZONTAL CELLS TO CONE PHOTORECEPTORS IN THE VERTEBRATE RETINA

      Progress in retinal and eye research
    76. MURAKAMI M; MIYACHI EI; TAKAHASHI KI
      MODULATION OF GAP-JUNCTIONS BETWEEN HORIZONTAL CELLS BY 2ND-MESSENGERS

      Progress in retinal and eye research
    77. COOK JE; BECKER DL
      GAP-JUNCTIONS IN THE VERTEBRATE RETINA

      Microscopy research and technique
    78. REIFSNIDER ES; TRANCHINA D
      BACKGROUND CONTRAST MODULATES KINETICS AND LATERAL SPREAD OF RESPONSES TO SUPERIMPOSED STIMULI IN OUTER RETINA

      Visual neuroscience
    79. AHNELT PK; HOKOC JN; ROHLICH P
      PHOTORECEPTORS IN A PRIMITIVE MAMMAL, THE SOUTH-AMERICAN OPOSSUM, DIDELPHIS-MARSUPIALIS-AURITA - CHARACTERIZATION WITH ANTI-OPSIN IMMUNOLABELING

      Visual neuroscience
    80. YAZULLA S; STUDHOLME KM
      VOLUME TRANSMISSION OF DOPAMINE MAY MODULATE LIGHT-ADAPTIVE PLASTICITY OF HORIZONTAL CELL DENDRITES IN THE RECOVERY PHASE FOLLOWING DOPAMINE DEPLETION IN GOLDFISH RETINA

      Visual neuroscience
    81. ZHU BS; GIBBINS I
      SYNAPTIC CIRCUITRY OF NEUROPEPTIDE-CONTAINING AMACRINE CELLS IN THE RETINA OF THE CANE TOAD, BUFO-MARINUS

      Visual neuroscience
    82. BLOOMFIELD SA; XIN DY; PERSKY SE
      A COMPARISON OF RECEPTIVE-FIELD AND TRACER COUPLING SIZE OF HORIZONTAL CELLS IN THE RABBIT RETINA

      Visual neuroscience
    83. BALDRIDGE WH; WEILER R; DOWLING JE
      DARK-SUPPRESSION AND LIGHT-SENSITIZATION OF HORIZONTAL CELL RESPONSESIN THE HYBRID BASS RETINA

      Visual neuroscience
    84. BENNIS M; VERSAUXBOTTERI C
      CATECHOLAMINE-CONTAINING, INDOLEAMINE-CONTAINING, AND GABA-CONTAININGCELLS IN THE CHAMELEON RETINA

      Visual neuroscience
    85. SMITH RG
      SIMULATION OF AN ANATOMICALLY DEFINED LOCAL CIRCUIT - THE CONE-HORIZONTAL CELL NETWORK IN CAT RETINA

      Visual neuroscience
    86. PICCOLINO M; PIGNATELLI A; SAPPIA F
      SUSTAINED OSCILLATORY NOISE IN THE LIGHT RESPONSES OF A RETINAL NEURON

      Nuovo cimento della Societa italiana di fisica. D, Condensed matter,atomic, molecular and chemical physics, biophysics
    87. DELAVILLA P; KURAHASHI T; KANEKO A
      L-GLUTAMATE-INDUCED RESPONSES AND CGMP-ACTIVATED CHANNELS IN 3 SUBTYPES OF RETINAL BIPOLAR CELLS DISSOCIATED FROM THE CAT

      The Journal of neuroscience
    88. DJAMGOZ MBA
      DIVERSITY OF GABA RECEPTORS IN THE VERTEBRATE OUTER RETINA

      Trends in neurosciences
    89. CUENCA N; DEJUAN J; KOLB H
      SUBSTANCE P-IMMUNOREACTIVE NEURONS IN THE HUMAN RETINA

      Journal of comparative neurology
    90. CHIBA C; SAITO T
      RESPONSES MEDIATED BY EXCITATORY AND INHIBITORY AMINO-ACID RECEPTORS IN SOLITARY SPIKING CELLS FROM NORMAL NEWT RETINA

      Japanese Journal of Physiology
    91. HAMPSON ECGM; WEILER R; VANEY DI
      PH-GATED DOPAMINERGIC MODULATION OF HORIZONTAL CELL GAP-JUNCTIONS IN MAMMALIAN RETINA

      Proceedings - Royal Society. Biological Sciences
    92. YANG CY; YAZULLA S
      GLUTAMATE-IMMUNOREACTIVITIES, GABA-IMMUNOREACTIVITIES, AND GAD-IMMUNOREACTIVITIES CO-LOCALIZE IN BIPOLAR CELLS OF TIGER SALAMANDER RETINA

      Visual neuroscience
    93. YANG CY; YAZULLA S
      GLUTAMATE-IMMUNOREACTIVITIES, GABA-IMMUNOREACTIVITIES, AND GAD-IMMUNOREACTIVITIES CO-LOCALIZE IN BIPOLAR CELLS OF TIGER SALAMANDER RETINA

      Visual neuroscience
    94. UMINO O; MAEHARA M; HIDAKA S; KITA S; HASHIMOTO Y
      THE NETWORK PROPERTIES OF BIPOLAR-BIPOLAR CELL COUPLING IN THE RETINAOF TELEOST FISHES

      Visual neuroscience
    95. MIGUELHIDALGO JJ; SNIDER CJ; ANGELIDES KJ; CHALUPA LM
      VOLTAGE-DEPENDENT SODIUM-CHANNEL ALPHA-SUBUNIT IMMUNOREACTIVITY IS EXPRESSED BY DISTINCT CELL-TYPES OF THE CAT AND MONKEY RETINA

      Visual neuroscience
    96. WATT CB; GLAZEBROOK PA; FLORACK VJ
      LOCALIZATION OF SUBSTANCE-P AND GABA IN RETINOTECTAL GANGLION-CELLS OF THE LARVAL TIGER SALAMANDER

      Visual neuroscience
    97. RIEKE F; SCHWARTZ EA
      A CGMP-GATED CURRENT CAN CONTROL EXOCYTOSIS AT CONE SYNAPSES

      Neuron
    98. RIEKE F; SCHWARTZ EA
      A CGMP-GATED CURRENT CAN CONTROL EXOCYTOSIS AT CONE SYNAPSES

      Neuron
    99. GOTTLOB I; STRENN K; SCHNEIDER B
      EFFECT OF LEVODOPA ON THE HUMAN DARK-ADAPTATION THRESHOLD

      Graefe's archive for clinical and experimental ophthalmology
    100. DAVANGER S; TORP R; OTTERSEN OP
      COLOCALIZATION OF GLUTAMATE AND HOMOCYSTEIC ACID IMMUNOREACTIVITIES IN HUMAN PHOTORECEPTOR TERMINALS

      Neuroscience


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Documento generato il 04/08/20 alle ore 22:46:46