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La ricerca find articoli where soggetti phrase all words 'TRANSGENIC MOUSE MODEL' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 174 riferimenti
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    1. Cleveland, DW; Rothstein, JD
      From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS

      NATURE REVIEWS NEUROSCIENCE
    2. Urushitani, M; Shimohama, S
      The role of nitric oxide in amyotrophic lateral sclerosis

      AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS
    3. Cooter, R; Babidge, W; Mutimer, K; Wickham, P; Robinson, D; Kiroff, G; Chapman, A; Maddern, G
      Ultrasound-assisted lipoplasty

      ANZ journal of surgery
    4. Hawkins, WE; Clark, MS; Shima, A; Walter, RB; Winn, RN; Westerfield, M
      Four resource centers for fishes: Specifies, stocks, and services

      MARINE BIOTECHNOLOGY
    5. Hamilton, JA; Benson, MD
      Transthyretin: a review from a structural perspective

      CELLULAR AND MOLECULAR LIFE SCIENCES
    6. Claycombe, KJ; Meydani, SN
      Vitamin E and genome stability

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    7. Tascou, S; Nayernia, K; Meinhardt, A; Schweyer, S; Engel, W; Trappe, R; Burfeind, P
      Targeted expression of SV40 large tumour antigen (TAg) induces a transientenhancement of spermatocyte proliferation and apoptosis

      MOLECULAR HUMAN REPRODUCTION
    8. Halliwell, B
      Role of free radicals in the neurodegenerative diseases - Therapeutic implications for antioxidant treatment

      DRUGS & AGING
    9. Hughes, RE; Olson, JM
      Therapeutic opportunities in polyglutamine disease

      NATURE MEDICINE
    10. Peters, B; Kirfel, J; Bussow, H; Vidal, M; Magin, TM
      Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex

      MOLECULAR BIOLOGY OF THE CELL
    11. Mayer, S; Eller, MS; Gilchrest, BA
      The SOS response in human skin

      CURRENT PROBLEMS IN DERMATOLOGY-US
    12. Zander, C; Takahashi, J; El Hachimi, KH; Fujigasaki, H; Albanese, V; Lebre, AS; Stevanin, G; Duyckaerts, C; Brice, A
      Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3

      HUMAN MOLECULAR GENETICS
    13. Petersen, A; Larsen, KE; Behr, GG; Romero, N; Przedborski, S; Brundin, P; Sulzer, D
      Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration

      HUMAN MOLECULAR GENETICS
    14. Jana, NR; Zemskov, EA; Wang, GH; Nukina, N
      Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

      HUMAN MOLECULAR GENETICS
    15. Nagano, S; Satoh, M; Sumi, H; Fujimura, H; Tohyama, C; Yanagihara, T; Sakoda, S
      Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose-dependent manner

      EUROPEAN JOURNAL OF NEUROSCIENCE
    16. Saenz-Robles, MT; Sullivan, CS; Pipas, JM
      Transforming functions of Simian Virus 40

      ONCOGENE
    17. Wong, PC; Cai, HB; Borchelt, DR; Price, DL
      Genetically engineered models relevant to neurodegenerative disorders - Their value for understanding disease mechanisms and designing/testing experimental therapeutics

      JOURNAL OF MOLECULAR NEUROSCIENCE
    18. Koudinov, AR; Koudinova, NV
      Essential role for cholesterol in synaptic plasticity and neuronal degeneration

      FASEB JOURNAL
    19. Almer, G; Guegan, C; Teismann, P; Naini, A; Rosoklija, G; Hays, AP; Chen, CP; Przedborski, S
      Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis

      ANNALS OF NEUROLOGY
    20. Deckel, AW
      Nitric oxide and nitric oxide synthase in Huntington's disease

      JOURNAL OF NEUROSCIENCE RESEARCH
    21. Sathasivam, S; Ince, PG; Shaw, PJ
      Apoptosis in amyotrophic lateral sclerosis: a review of the evidence

      NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
    22. Michel, ML; Loirat, D
      DNA vaccines for prophylactic or therapeutic immunization against hepatitis B

      INTERVIROLOGY
    23. Brown, RH; Robberecht, W
      Amyotrophic lateral sclerosis: Pathogenesis

      SEMINARS IN NEUROLOGY
    24. Martin-Aparicio, E; Yamamoto, A; Hernandez, F; Hen, R; Avila, JS; Lucas, JJ
      Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease

      JOURNAL OF NEUROSCIENCE
    25. Guegn, C; Vila, M; Rosoklija, G; Hays, AP; Przedborski, S
      Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

      JOURNAL OF NEUROSCIENCE
    26. Catania, MV; Aronica, E; Yankaya, B; Troost, D
      Increased expression of neuronal nitric oxide synthase spliced variants inreactive astrocytes of amyotrophic lateral sclerosis human spinal cord

      JOURNAL OF NEUROSCIENCE
    27. Michel, ML; Pol, S; Brechot, C; Tiollais, P
      Immunotherapy of chronic hepatitis B by anti HBV vaccine: from present to future

      VACCINE
    28. Riedout, HJ; Stefanis, L
      Caspase inhibition: a potential therapeutic strategy in neurological diseases

      HISTOLOGY AND HISTOPATHOLOGY
    29. Brede, M; Hein, L
      Transgenic mouse models of angiotensin receptor subtype function in the cardiovascular system

      REGULATORY PEPTIDES
    30. Beckman, JS; Estevez, AG; Crow, JR
      Superoxide dismutase and the death of motoneurons in ALS

      TRENDS IN NEUROSCIENCES
    31. McMurray, CT
      Huntington's disease: new hope for therapeutics

      TRENDS IN NEUROSCIENCES
    32. Dubois-Dauphin, M; Pfister, Y; Vallet, PG; Savioz, A
      Prevention of apoptotic neuronal death by controlling procaspases? A pointof view

      BRAIN RESEARCH REVIEWS
    33. Klein, JC; Beems, RB; Zwart, PE; Hamzink, M; Zomer, G; van Steeg, H; van Kreijl, CF
      Intestinal toxicity and carcinogenic potential of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in DNA repair deficient XPA(-/-) mice

      CARCINOGENESIS
    34. Julien, JP
      Amyotrophic lateral sclerosis: Unfolding the toxicity of the misfolded

      CELL
    35. Suehiro, K; Takuma, S; Shimizu, J; Hozumi, T; Yano, H; Cardinale, C; DiTullio, MR; Wang, J; Smith, CR; Burkhoff, D; Homma, S
      Assessment of left ventricular systolic function using contrast two-dimensional echocardiography with a high-frequency transducer in the awake murinemodel of myocardial infarction

      JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
    36. Fibach, E
      Cell culture and animal models to screen for promising fetal hemoglobin-stimulating compounds

      SEMINARS IN HEMATOLOGY
    37. Sykes, PJ; McCallum, BD; Bangay, MJ; Hooker, AM; Morley, AA
      Effect of exposure to 900 MHz radiofrequency radiation on intrachromosomalrecombination in pKZ1 mice

      RADIATION RESEARCH
    38. Rowland, LP; Shneider, NA
      Medical progress: Amyotrophic lateral sclerosis.

      NEW ENGLAND JOURNAL OF MEDICINE
    39. Orrell, RW; Figlewicz, DA
      Clinical implications of the genetics of ALS and other motor neuron diseases

      NEUROLOGY
    40. Parker, JA; Connolly, JB; Wellington, C; Hayden, M; Dausset, J; Neri, C
      Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    41. Bendotti, C; Calvaresi, N; Chiveri, L; Prelle, A; Moggio, M; Braga, M; Silani, V; De Biasi, S
      Early vacuolization and mitochondrial damage in motor neurons of FALS miceare not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    42. Lee, M; Hyun, DH; Halliwell, B; Jenner, P
      Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2

      JOURNAL OF NEUROCHEMISTRY
    43. Wolfe, MS
      Secretase targets for Alzheimer's disease: Identification and therapeutic potential

      JOURNAL OF MEDICINAL CHEMISTRY
    44. Keene, CD; Rodrigues, CMP; Eich, T; Linehan-Stieers, C; Abt, A; Kren, BT; Steer, CJ; Low, WC
      A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease

      EXPERIMENTAL NEUROLOGY
    45. Anneser, JMH; Cookson, MR; Ince, PG; Shaw, PJ; Borasio, GD
      Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis

      EXPERIMENTAL NEUROLOGY
    46. Maimone, D; Dominici, R; Grimaldi, LME
      Pharmacogenomics of neurodegenerative diseases

      EUROPEAN JOURNAL OF PHARMACOLOGY
    47. Hadsell, DL; Alexeenko, T; Klemintidis, Y; Torres, D; Lee, AV
      Inability of overexpressed des(1-3)human insulin-like growth factor I (IGF-I) to inhibit forced mammary gland involution is associated with decreasedexpression of IGF signaling molecules

      ENDOCRINOLOGY
    48. Nagel, RL; Fabry, ME
      The panoply of animal models for sickle cell anaemia

      BRITISH JOURNAL OF HAEMATOLOGY
    49. D'Hooge, R; Van Dam, D; Franck, F; Gieselmann, V; De Deyn, PP
      Hyperactivity, neuromotor defects, and impaired learning and memory in a mouse model for metachromatic leukodystrophy

      BRAIN RESEARCH
    50. Keep, M; Elmer, E; Fong, KSK; Csiszar, K
      Intrathecal cyclosporin prolongs survival of late-stage ALS mice

      BRAIN RESEARCH
    51. Fabry, ME; Suzuka, SM; Weinberg, RS; Lawrence, C; Factor, SM; Gilman, JG; Costantini, F; Nagel, RL
      Second generation knockout sickle mice: the effect of HbF

      BLOOD
    52. Dunnett, SB
      Reverse transcription of inserted DNA in a monkey gives us ANDi

      TRENDS IN PHARMACOLOGICAL SCIENCES
    53. Doble, A; Kennel, P
      Animal models of amyotrophic lateral sclerosis

      AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS
    54. Xu, ZS
      Mechanism and treatment of motoneuron degeneration in ALS: What have SOD1 mutants told us?

      AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS
    55. Shibata, N; Hirano, A; Yamamoto, T; Kato, Y; Kobayashi, M
      Superoxide dismutase-1 mutation-related neurotoxicity in familial amyotrophic lateral sclerosis

      AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS
    56. Pioro, EP
      Antioxidant therapy in ALS

      AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS
    57. Couldrey, C; Green, JE
      Metastases: the glycan connection

      BREAST CANCER RESEARCH
    58. Bertoletti, A; Maini, MK
      Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?

      CURRENT OPINION IN MICROBIOLOGY
    59. Bouhassira, EE; Acharya, AS
      Towards gene therapy of sickle cell disease

      EXPERT OPINION ON THERAPEUTIC PATENTS
    60. Martin, LJ; Price, AC; Kaiser, A; Shaikh, AY; Liu, ZP
      Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death (Review)

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    61. Medina, D
      The preneoplastic phenotype in murine mammary tumorigenesis

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    62. Karlsson, S
      The first steps on the gene therapy pathway to anti-sickling success

      NATURE MEDICINE
    63. Alisky, JM; Davidson, BL
      Gene therapy for amyotrophic lateral sclerosis and other motor neuron diseases

      HUMAN GENE THERAPY
    64. Jaarsma, D; Haasdijk, ED; Grashorn, JAC; Hawkins, R; van Duijn, W; Verspaget, HW; London, J; Holstege, JC
      Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1

      NEUROBIOLOGY OF DISEASE
    65. Couillard-Despres, S; Meier, J; Julien, JP
      Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase

      NEUROBIOLOGY OF DISEASE
    66. Campbell, KM; Veldman, MB; McGrath, MJ; Burton, FH
      TS plus OCD-like neuropotentiated mice are supersensitive to seizure induction

      NEUROREPORT
    67. Bertoletti, A; Maini, MK
      Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?

      CURRENT OPINION IN IMMUNOLOGY
    68. Hadsell, DL; Murphy, KL; Bonnette, SG; Reece, N; Laucirica, R; Rosen, JM
      Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis

      ONCOGENE
    69. Pedersen, WA; Luo, H; Kruman, I; Kasarskis, E; Mattson, MP
      The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis

      FASEB JOURNAL
    70. Lau, GKK
      Use of immunomodulatory therapy (other than interferon) for the treatment of chronic hepatitis B virus infection

      JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
    71. Holschneider, DP; Shih, JC
      Genotype to phenotype: challenges and opportunities

      INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
    72. Chen, Y; Megosh, LC; Gilmour, SK; Sawicki, JA; O'Brien, TG
      K6/ODC transgenic mice as a sensitive model for carcinogen identification

      TOXICOLOGY LETTERS
    73. Ludolph, AC
      Treatment of amyotrophic lateral sclerosis - What is the next step?

      JOURNAL OF NEUROLOGY
    74. Robberecht, W
      Oxidative stress in amyotrophic lateral sclerosis

      JOURNAL OF NEUROLOGY
    75. Ludolph, AC; Meyer, T; Riepe, MW
      The role of excitotoxicity in ALS - what is the evidence?

      JOURNAL OF NEUROLOGY
    76. Sasaki, S; Shibata, N; Komori, T; Iwata, M
      iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis

      NEUROSCIENCE LETTERS
    77. Wojcik, SM; Bundman, DS; Roop, DR
      Delayed wound healing in keratin 6a knockout mice

      MOLECULAR AND CELLULAR BIOLOGY
    78. Bostwick, DG; Ramnani, D; Qian, JQ
      Prostatic intraepithelial neoplasia: Animal models 2000

      PROSTATE
    79. Diwan, BA; Ramakrishna, G; Anderson, LM; Ramljak, D
      Overexpression of Grb2 in inflammatory lesions and preneoplastic foci and tumors induced by N-nitrosodimethylamine in helicobacter hepaticus-infectedand -noninfected A/J mice

      TOXICOLOGIC PATHOLOGY
    80. Jilbert, AR; Kotlarski, I
      Immune responses to duck hepatitis B virus infection

      DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
    81. Iannaccone, PM
      The "new" genetics and mammalian cloning in environmental health research

      ENVIRONMENTAL HEALTH PERSPECTIVES
    82. Levine, MH; Haberman, AM; Sant'Angelo, DB; Hannum, LG; Cancro, MP; Janeway, CA; Shlomchik, MJ
      A B-cell receptor-specific selection step governs immature to mature B cell differentiation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    83. Nguyen, MD; Lariviere, RC; Julien, JP
      Reduction of axonal caliber does not alleviate motor neuron disease causedby mutant superoxide dismutase 1

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    84. Rowland, LP
      Six important themes in amyotrophic lateral sclerosis (ALS) research, 1999

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    85. Hurko, O; Walsh, FS
      Novel drug development for amyotrophic lateral sclerosis

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    86. Azzouz, M; Poindron, P; Guettier, S; Leclerc, N; Andres, C; Warter, JM; Borg, J
      Prevention of mutant SOD1 motoneuron degeneration by copper chelators in vitro

      JOURNAL OF NEUROBIOLOGY
    87. Loirat, D; Lemonnier, FA; Michel, ML
      Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization

      JOURNAL OF IMMUNOLOGY
    88. Maini, MK; Boni, C; Lee, CK; Larrubia, JR; Reignat, S; Ogg, GS; King, AS; Herberg, J; Gilson, R; Alisa, A; Williams, R; Vergani, D; Naoumov, NV; Ferrari, C; Bertoletti, A
      The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

      JOURNAL OF EXPERIMENTAL MEDICINE
    89. Wijnhoven, SWP; Kool, HJM; van Oostrom, CTM; Beems, RB; Mullenders, LHF; van Zeeland, AA; van der Horst, GTJ; Vrieling, H; van Steeg, H
      The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient cockayne syndrome group B mice

      CANCER RESEARCH
    90. Liu, HB; Zhu, HN; Eggers, DK; Nersissian, AM; Faull, KF; Goto, JJ; Ai, JY; Sanders-Loehr, J; Gralla, EB; Valentine, JS
      Copper(2+) binding to the surface residue cysteine 111 of His46Arg human copper-zinc superoxide dismutase, a familial amyotrophic lateral sclerosis mutant

      BIOCHEMISTRY
    91. Steckler, T; Holsboer, F; Reul, JMHM
      Glucocorticoids and depression

      BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
    92. Richards, SJ; Dunnett, SB
      Genetic models of Alzheimer's disease and their psychopathological validity

      ALZHEIMERS REPORTS
    93. Becker, DA
      Diagnostic and therapeutic applications of azulenyl nitrone spin traps

      CELLULAR AND MOLECULAR LIFE SCIENCES
    94. Sykes, PJ; Hooker, AM; Morley, AA
      Inversion due to intrachromosomal recombination produced by carcinogens ina transgenic mouse model

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    95. Hull, M; Fiebich, BL; Schumann, G; Lieb, K; Bauer, J
      Anti-inflammatory substances a new therapeutic option in Alzheimer's disease

      DRUG DISCOVERY TODAY
    96. Barden, N
      Regulation of corticosteroid receptor gene expression in depression and antidepressant action

      JOURNAL OF PSYCHIATRY & NEUROSCIENCE
    97. Elliott, JL
      Experimental models of amyotrophic lateral sclerosis

      NEUROBIOLOGY OF DISEASE
    98. Waggoner, DJ; Bartnikas, TB; Gitlin, JD
      The role of copper in neurodegenerative disease

      NEUROBIOLOGY OF DISEASE
    99. Sunday, ME; Haley, KJ; Sikorski, K; Graham, SA; Emanuel, RL; Zhang, F; Mu, QQ; Shahsafaei, A; Hatzis, D
      Calcitonin driven v-Ha-ras induces multilineage pulmonary epithelial hyperplasias and neoplasms

      ONCOGENE
    100. Cleveland, DW
      From Charcot to SOD1: Mechanisms of selective motor neuron death in ALS

      NEURON


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/10/20 alle ore 14:18:56