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1. Zisman, A; Ng, CP; Pantuck, AJ; Bonavida, B; Belldegrun, AS
   Actinomycin D and gemcitabine synergistically sensitize androgen-independent prostate cancer cells to Apo2L/TRAIL-mediated apoptosis
   JOURNAL OF IMMUNOTHERAPY
   
   A. Zisman et al., "Actinomycin D and gemcitabine synergistically sensitize androgen-independent prostate cancer cells to Apo2L/TRAIL-mediated apoptosis", J IMMUNOTH, 24(6), 2001, pp. 459-471
2. Srivastava, RK
   TRAIL/Apo-2L: Mechanisms and clinical applications in cancer
   NEOPLASIA
   
   R.K. Srivastava, "TRAIL/Apo-2L: Mechanisms and clinical applications in cancer", NEOPLASIA, 3(6), 2001, pp. 535-546
3. Sartorius, U; Schmitz, I; Krammer, PH
   Molecular mechanisms of death-receptor-mediated apoptosis
   CHEMBIOCHEM
   
   U. Sartorius et al., "Molecular mechanisms of death-receptor-mediated apoptosis", CHEMBIOCHEM, 2(1), 2001, pp. 20-29
4. Mitsiades, N; Mitsiades, CS; Poulaki, V; Anderson, KC; Treon, SP
   Concepts in the use of TRAIL/Apo2L: an emerging biotherapy for myeloma andother neoplasias
   EXPERT OPINION ON INVESTIGATIONAL DRUGS
   
   N. Mitsiades et al., "Concepts in the use of TRAIL/Apo2L: an emerging biotherapy for myeloma andother neoplasias", EXPERT OP I, 10(8), 2001, pp. 1521-1530
5. Ichikawa, K; Liu, WM; Zhao, LM; Wang, Z; Liu, D; Ohtsuka, T; Zhang, HG; Mountz, JD; Koopman, WJ; Kimberly, RP; Zhou, T
   Tumoricidal activity of a novel anti-human DR5 monoclonal antibody withouthepatocyte cytotoxicity
   NATURE MEDICINE
   
   K. Ichikawa et al., "Tumoricidal activity of a novel anti-human DR5 monoclonal antibody withouthepatocyte cytotoxicity", NAT MED, 7(8), 2001, pp. 954-960
6. Pollack, IF; Erff, M; Ashkenazi, A
   Direct stimulation of apoptotic signaling by soluble Apo2L/tumor necrosis factor-related apoptosis-inducing ligand leads to selective killing of glioma cells
   CLINICAL CANCER RESEARCH
   
   I.F. Pollack et al., "Direct stimulation of apoptotic signaling by soluble Apo2L/tumor necrosis factor-related apoptosis-inducing ligand leads to selective killing of glioma cells", CLIN CANC R, 7(5), 2001, pp. 1362-1369
7. Nguyen, T; Zhang, XD; Hersey, P
   Relative resistance of fresh isolates of melanoma to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis
   CLINICAL CANCER RESEARCH
   
   T. Nguyen et al., "Relative resistance of fresh isolates of melanoma to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis", CLIN CANC R, 7(3), 2001, pp. 966S-973S
8. Nimmanapalli, R; Porosnicu, M; Nguyen, D; Worthington, E; O'Bryan, E; Perkins, C; Bhalla, K
   Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or Apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells
   CLINICAL CANCER RESEARCH
   
   R. Nimmanapalli et al., "Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or Apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells", CLIN CANC R, 7(2), 2001, pp. 350-357
9. Liu, WH; Bodle, E; Chen, JY; Gao, MX; Rosen, GD; Broaddus, VC
   Tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines
   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
   
   W.H. Liu et al., "Tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines", AM J RESP C, 25(1), 2001, pp. 111-118
10. Oshima, K; Yanase, N; Ibukiyama, C; Yamashina, A; Kayagaki, N; Yagita, H; Mizuguchi, J
    Involvement of trail/trail-R interaction in IFN-alpha-induced apoptosis ofdaudi B lymphoma cells
    CYTOKINE
    
    K. Oshima et al., "Involvement of trail/trail-R interaction in IFN-alpha-induced apoptosis ofdaudi B lymphoma cells", CYTOKINE, 14(4), 2001, pp. 193-201
11. Mitsiades, N; Poulaki, V; Mitsiades, CS; Koutras, DA; Chrousos, GR
    Apoptosis induced FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases
    TRENDS IN ENDOCRINOLOGY AND METABOLISM
    
    N. Mitsiades et al., "Apoptosis induced FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases", TRENDS ENDO, 12(9), 2001, pp. 384-390
12. Mow, BMF; Blajeski, AL; Chandra, J; Kaufmann, SH
    Apoptosis and the response to anticancer therapy
    CURRENT OPINION IN ONCOLOGY
    
    B.M.F. Mow et al., "Apoptosis and the response to anticancer therapy", CURR OPIN O, 13(6), 2001, pp. 453-462
13. Wei, XC; Wang, XJ; Chen, K; Zhang, L; Liang, Y; Lin, XL
    Killing effect of TNF-related apoptosis inducing ligand regulated by tetracycline on gastric cancer cell line NCI-N87
    WORLD JOURNAL OF GASTROENTEROLOGY
    
    X.C. Wei et al., "Killing effect of TNF-related apoptosis inducing ligand regulated by tetracycline on gastric cancer cell line NCI-N87", WORLD J GAS, 7(4), 2001, pp. 559-562
14. Kasof, GM; Lu, JJ; Liu, DR; Speer, B; Mongan, KN; Gomes, BC; Lorenzi, MV
    Tumor necrosis factor-alpha induces the expression of DR6, a member of theTNF receptor family, through activation of NF-kappa B
    ONCOGENE
    
    G.M. Kasof et al., "Tumor necrosis factor-alpha induces the expression of DR6, a member of theTNF receptor family, through activation of NF-kappa B", ONCOGENE, 20(55), 2001, pp. 7965-7975
15. Satoh, K; Kaneko, K; Hirota, M; Masamune, A; Satoh, A; Shimosegawa, T
    Tumor necrosis factor-related apoptosis-inducing ligand and its receptor expression and the pathway of apoptosis in human pancreatic cancer
    PANCREAS
    
    K. Satoh et al., "Tumor necrosis factor-related apoptosis-inducing ligand and its receptor expression and the pathway of apoptosis in human pancreatic cancer", PANCREAS, 23(3), 2001, pp. 251-258
16. Liu, Q; El-Deiry, WS; Gazitt, Y
    Additive effect of Apo2L/TRAIL and Adeno-p53 in the induction of apoptosisin myeloma cell lines
    EXPERIMENTAL HEMATOLOGY
    
    Q. Liu et al., "Additive effect of Apo2L/TRAIL and Adeno-p53 in the induction of apoptosisin myeloma cell lines", EXP HEMATOL, 29(8), 2001, pp. 962-970
17. Golby, SJC; Spencer, J
    Role of innate immunity in cancer
    CURRENT OPINION IN GASTROENTEROLOGY
    
    S.J.C. Golby e J. Spencer, "Role of innate immunity in cancer", CURR OPIN G, 17(6), 2001, pp. 568-572
18. Guo, BC; Xu, YH
    Anti-human hepatocellular carcinoma effects of tumor necrosis factor-related apoptosis-inducing ligand in vivo and in vitro
    ACTA PHARMACOLOGICA SINICA
    
    B.C. Guo e Y.H. Xu, "Anti-human hepatocellular carcinoma effects of tumor necrosis factor-related apoptosis-inducing ligand in vivo and in vitro", ACT PHAR SI, 22(9), 2001, pp. 831-836
19. Simon, AK; Williams, O; Mongkolsapaya, J; Jin, B; Xu, XN; Walczak, H; Screaton, GR
    Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: Sensitivity of human thymocytes
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    A.K. Simon et al., "Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: Sensitivity of human thymocytes", P NAS US, 98(9), 2001, pp. 5158-5163
20. Lum, JJ; Pilon, AA; Sanchez-Dardon, J; Phenix, BN; Kim, JE; Mihowich, J; Jamison, K; Hawley-Foss, N; Lynch, DH; Badley, AD
    Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2L
    JOURNAL OF VIROLOGY
    
    J.J. Lum et al., "Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2L", J VIROLOGY, 75(22), 2001, pp. 11128-11136
21. Mizutani, Y; Nakao, M; Ogawa, O; Yoshida, O; Bonavida, B; Miki, T
    Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin
    JOURNAL OF UROLOGY
    
    Y. Mizutani et al., "Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin", J UROL, 165(1), 2001, pp. 263-270
22. Qin, JZ; Bacon, P; Chaturvedi, V; Nickoloff, BJ
    Role of NF-kappa B activity in apoptotic response of keratinocytes mediated by interferon-gamma, tumor necrosis factor-alpha, and tumor-necrosis-factor-related apoptosis-inducing ligand
    JOURNAL OF INVESTIGATIVE DERMATOLOGY
    
    J.Z. Qin et al., "Role of NF-kappa B activity in apoptotic response of keratinocytes mediated by interferon-gamma, tumor necrosis factor-alpha, and tumor-necrosis-factor-related apoptosis-inducing ligand", J INVES DER, 117(4), 2001, pp. 898-907
23. Bullani, RR; Huard, B; Viard-Leveugle, I; Byers, HR; Irmler, M; Saurat, JH; Tschopp, J; French, LE
    Selective expression of FLIP in malignant melanocytic skin lesions
    JOURNAL OF INVESTIGATIVE DERMATOLOGY
    
    R.R. Bullani et al., "Selective expression of FLIP in malignant melanocytic skin lesions", J INVES DER, 117(2), 2001, pp. 360-364
24. Vidalain, PO; Azocar, O; Yagita, H; Rabourdin-Combe, C; Servet-Delprat, C
    Cytotoxic activity of human dendritic cells is differentially regulated bydouble-stranded RNA and CD40 ligand
    JOURNAL OF IMMUNOLOGY
    
    P.O. Vidalain et al., "Cytotoxic activity of human dendritic cells is differentially regulated bydouble-stranded RNA and CD40 ligand", J IMMUNOL, 167(7), 2001, pp. 3765-3772
25. Baetu, TM; Kwon, H; Sharma, S; Grandvaux, N; Hiscott, J
    Disruption of NF-kappa B signaling reveals a novel role for NF-kappa B in the regulation of TNF-related apoptosis-inducing ligand expression
    JOURNAL OF IMMUNOLOGY
    
    T.M. Baetu et al., "Disruption of NF-kappa B signaling reveals a novel role for NF-kappa B in the regulation of TNF-related apoptosis-inducing ligand expression", J IMMUNOL, 167(6), 2001, pp. 3164-3173
26. Franco, AV; Zhang, XD; Van Berkel, E; Sanders, JE; Zhang, XY; Thomas, WD; Nguyen, T; Hersey, P
    The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells
    JOURNAL OF IMMUNOLOGY
    
    A.V. Franco et al., "The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells", J IMMUNOL, 166(9), 2001, pp. 5337-5345
27. Liu, SX; Yu, YZ; Zhang, MH; Wang, WY; Cao, XT
    The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells
    JOURNAL OF IMMUNOLOGY
    
    S.X. Liu et al., "The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells", J IMMUNOL, 166(9), 2001, pp. 5407-5415
28. Pettersen, RD; Bernard, G; Olafsen, MK; Pourtein, M; Lie, SO
    CD99 signals caspase-independent T cell death
    JOURNAL OF IMMUNOLOGY
    
    R.D. Pettersen et al., "CD99 signals caspase-independent T cell death", J IMMUNOL, 166(8), 2001, pp. 4931-4942
29. Kischkel, FC; Lawrence, DA; Tinel, A; LeBlanc, H; Virmani, A; Schow, P; Gazdar, A; Blenis, J; Arnott, D; Ashkenazi, A
    Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    F.C. Kischkel et al., "Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.", J BIOL CHEM, 276(49), 2001, pp. 46639-46646
30. Han, ZY; Pantazis, P; Wyche, JH; Kouttab, N; Kidd, VJ; Hendrickson, EA
    A Fas-associated Death Domain Protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    Z.Y. Han et al., "A Fas-associated Death Domain Protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line", J BIOL CHEM, 276(42), 2001, pp. 38748-38754
31. Harper, N; Farrow, SN; Kaptein, A; Cohen, GM; MacFarlane, M
    Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-kappa B activation by inhibition of apical caspases
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    N. Harper et al., "Modulation of tumor necrosis factor apoptosis-inducing ligand-induced NF-kappa B activation by inhibition of apical caspases", J BIOL CHEM, 276(37), 2001, pp. 34743-34752
32. Varela, N; Munoz-Pinedo, C; Ruiz-Ruiz, C; Robledo, G; Pedroso, M; Lopez-Rivas, A
    Interferon-gamma sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    N. Varela et al., "Interferon-gamma sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism", J BIOL CHEM, 276(21), 2001, pp. 17779-17787
33. McDonald, ER; Chui, PC; Martelli, PF; Dicker, DT; El-Deiry, WS
    Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    E.R. McDonald et al., "Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling", J BIOL CHEM, 276(18), 2001, pp. 14939-14945
34. Panka, DJ; Mano, T; Suhara, T; Walsh, K; Mier, JW
    Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    D.J. Panka et al., "Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells", J BIOL CHEM, 276(10), 2001, pp. 6893-6896
35. Helmbach, H; Rossmann, E; Kern, MA; Schadendorf, D
    Drug-resistance in human melanoma
    INTERNATIONAL JOURNAL OF CANCER
    
    H. Helmbach et al., "Drug-resistance in human melanoma", INT J CANC, 93(5), 2001, pp. 617-622
36. Shin, EC; Ahn, JM; Kim, CH; Choi, Y; Ahn, YS; Kim, H; Kim, SJ; Park, JH
    IFN-gamma induces cell death in human hepatoma cells through a trail/deathreceptor-mediated apoptotic pathway
    INTERNATIONAL JOURNAL OF CANCER
    
    E.C. Shin et al., "IFN-gamma induces cell death in human hepatoma cells through a trail/deathreceptor-mediated apoptotic pathway", INT J CANC, 93(2), 2001, pp. 262-268
37. Park, WS; Lee, JH; Shin, MS; Park, JY; Kim, HS; Kim, YS; Park, CH; Lee, SK; Lee, SH; Lee, SN; Kim, H; Yoo, NJ; Lee, JY
    Inactivating mutations of KILLER/DR5 gene in gastric cancers
    GASTROENTEROLOGY
    
    W.S. Park et al., "Inactivating mutations of KILLER/DR5 gene in gastric cancers", GASTROENTY, 121(5), 2001, pp. 1219-1225
38. Yoshida, T; Maeda, A; Tani, N; Sakai, T
    Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene
    FEBS LETTERS
    
    T. Yoshida et al., "Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene", FEBS LETTER, 507(3), 2001, pp. 381-385
39. Mitsiades, N; Poulaki, V; Mitsiades, C; Tsokos, M
    Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5
    CANCER RESEARCH
    
    N. Mitsiades et al., "Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5", CANCER RES, 61(6), 2001, pp. 2704-2712
40. Eggert, A; Grotzer, MA; Zuzak, TJ; Wiewrodt, BR; Ho, R; Ikegaki, N; Brodeur, GM
    Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
    CANCER RESEARCH
    
    A. Eggert et al., "Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression", CANCER RES, 61(4), 2001, pp. 1314-1319
41. Lacour, S; Hammann, A; Wotawa, A; Corcos, L; Solary, E; Dimanche-Boitrel, MT
    Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
    CANCER RESEARCH
    
    S. Lacour et al., "Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis", CANCER RES, 61(4), 2001, pp. 1645-1651
42. Nimmanapalli, R; Perkins, CL; Orlando, M; O'Bryan, E; Nguyen, D; Bhalla, KN
    Pretreatment with paclitaxel enhances Apo-2 ligand tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cellsby inducing death receptors 4 and 5 protein levels
    CANCER RESEARCH
    
    R. Nimmanapalli et al., "Pretreatment with paclitaxel enhances Apo-2 ligand tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cellsby inducing death receptors 4 and 5 protein levels", CANCER RES, 61(2), 2001, pp. 759-763
43. Zhang, XD; Zhang, XY; Gray, CP; Nguyen, T; Hersey, P
    Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by Smac/DIABLO release from mitochondria
    CANCER RESEARCH
    
    X.D. Zhang et al., "Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by Smac/DIABLO release from mitochondria", CANCER RES, 61(19), 2001, pp. 7339-7348
44. Huang, Y; He, Q; Hillman, MJ; Rong, R; Sheikh, MS
    Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells
    CANCER RESEARCH
    
    Y. Huang et al., "Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells", CANCER RES, 61(18), 2001, pp. 6918-6924
45. Cuello, M; Ettenberg, SA; Clark, AS; Keane, MM; Posner, RH; Nau, MM; Dennis, PA; Lipkowitz, S
    Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhancestumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosisin breast and ovarian cancer cell lines that overexpress erbB-2
    CANCER RESEARCH
    
    M. Cuello et al., "Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhancestumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosisin breast and ovarian cancer cell lines that overexpress erbB-2", CANCER RES, 61(12), 2001, pp. 4892-4900
46. Fiumara, P; Younes, A
    CD40 ligand (CD154) and tumour necrosis factor-related apoptosis inducing ligand (APO-2L) in haematological malignancies
    BRITISH JOURNAL OF HAEMATOLOGY
    
    P. Fiumara e A. Younes, "CD40 ligand (CD154) and tumour necrosis factor-related apoptosis inducing ligand (APO-2L) in haematological malignancies", BR J HAEM, 113(2), 2001, pp. 265-274
47. Chen, Q; Gong, B; Mahmoud-Ahmed, AS; Zhou, A; Hsi, ED; Hussein, M; Almasan, A
    Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced in multiple myeloma
    BLOOD
    
    Q. Chen et al., "Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced in multiple myeloma", BLOOD, 98(7), 2001, pp. 2183-2192
48. Secchiero, P; Gonelli, A; Celeghini, C; Mirandola, P; Guidotti, L; Visani, G; Capitani, S; Zauli, G
    Activation of the nitric oxide synthase pathway represents a key componentof tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies
    BLOOD
    
    P. Secchiero et al., "Activation of the nitric oxide synthase pathway represents a key componentof tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies", BLOOD, 98(7), 2001, pp. 2220-2228
49. Zang, DY; Goodwin, RG; Loken, MR; Bryant, E; Deeg, HJ
    Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: effects on in vitro hemopoiesis
    BLOOD
    
    D.Y. Zang et al., "Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: effects on in vitro hemopoiesis", BLOOD, 98(10), 2001, pp. 3058-3065
50. Shinohara, H; Kayagaki, N; Yagita, H; Oyaizu, N; Ohba, M; Kuroki, T; Ikawa, Y
    A protective role of PKC epsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    
    H. Shinohara et al., "A protective role of PKC epsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells", BIOC BIOP R, 284(5), 2001, pp. 1162-1167
51. Schmitz, I; Kirchhoff, S; Krammer, PH
    Regulation of death receptor-mediated apoptosis pathways
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    
    I. Schmitz et al., "Regulation of death receptor-mediated apoptosis pathways", INT J BIO C, 32(11-12), 2000, pp. 1123-1136
52. Pasechnik, V
    Microbial pathogens and apoptotic anticancer therapy
    EXPERT OPINION ON INVESTIGATIONAL DRUGS
    
    V. Pasechnik, "Microbial pathogens and apoptotic anticancer therapy", EXPERT OP I, 9(6), 2000, pp. 1243-1256
53. Dejosez, M; Ramp, U; Mahotka, C; Krieg, A; Walczak, H; Gabbert, HE; Gerharz, CD
    Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan
    CELL DEATH AND DIFFERENTIATION
    
    M. Dejosez et al., "Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan", CELL DEAT D, 7(11), 2000, pp. 1127-1136
54. Shiiki, K; Yoshikawa, H; Kinoshita, H; Takeda, M; Ueno, A; Nakajima, Y; Tasaka, K
    Potential mechanisms of resistance to TRAIL/Apo2L-induced apoptosis in human promyelocytic leukemia HL-60 cells during granulocytic differentiation
    CELL DEATH AND DIFFERENTIATION
    
    K. Shiiki et al., "Potential mechanisms of resistance to TRAIL/Apo2L-induced apoptosis in human promyelocytic leukemia HL-60 cells during granulocytic differentiation", CELL DEAT D, 7(10), 2000, pp. 939-946
55. Kischkel, FC; Lawrence, DA; Chuntharapai, A; Schow, P; Kim, KJ; Ashkenazi, A
    Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
    IMMUNITY
    
    F.C. Kischkel et al., "Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5", IMMUNITY, 12(6), 2000, pp. 611-620
56. Screaton, G; Xu, XN
    T cell life and death signalling via TNF-receptor family members
    CURRENT OPINION IN IMMUNOLOGY
    
    G. Screaton e X.N. Xu, "T cell life and death signalling via TNF-receptor family members", CURR OP IM, 12(3), 2000, pp. 316-322
57. Wang, TTY; Jeng, JJ
    Coordinated regulation of two TRAIL-R2/KILLER/DR5 mRNA isoforms by DNA damaging agents, serum and 17 beta-estradiol in human breast cancer cells
    BREAST CANCER RESEARCH AND TREATMENT
    
    T.T.Y. Wang e J.J. Jeng, "Coordinated regulation of two TRAIL-R2/KILLER/DR5 mRNA isoforms by DNA damaging agents, serum and 17 beta-estradiol in human breast cancer cells", BREAST CANC, 61(1), 2000, pp. 87-96
58. Wu, GS; Kim, K; El-Deiry, WS
    Killer/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death
    CANCER GENE THERAPY
    
    G.S. Wu et al., "Killer/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death", ADV EXP MED, 465, 2000, pp. 143-151
59. Murakami-Mori, K; Mori, S; Bonavida, B
    Molecular pathogenesis of AIDS-associated Kaposi's sarcoma: Growth and apoptosis
    ADVANCES IN CANCER RESEARCH, VOL 78
    
    K. Murakami-Mori et al., "Molecular pathogenesis of AIDS-associated Kaposi's sarcoma: Growth and apoptosis", ADV CANC R, 78, 2000, pp. 159-197
60. Chinnaiyan, AM; Prasad, U; Shankar, S; Hamstra, DA; Shanaiah, M; Chenevert, TL; Ross, BD; Rehemtulla, A
    Combined effect of tumor necrosis factor-related apoptosis-inducing ligandand ionizing radiation in breast cancer therapy
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    A.M. Chinnaiyan et al., "Combined effect of tumor necrosis factor-related apoptosis-inducing ligandand ionizing radiation in breast cancer therapy", P NAS US, 97(4), 2000, pp. 1754-1759
61. Wehrli, P; Viard, I; Bullani, R; Tschopp, J; French, LE
    Death receptors in cutaneous biology and disease
    JOURNAL OF INVESTIGATIVE DERMATOLOGY
    
    P. Wehrli et al., "Death receptors in cutaneous biology and disease", J INVES DER, 115(2), 2000, pp. 141-148
62. Griffith, TS; Anderson, RD; Davidson, BL; Williams, RD; Ratliff, TL
    Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/apo-2 ligand gene induces tumor cell apoptosis
    JOURNAL OF IMMUNOLOGY
    
    T.S. Griffith et al., "Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/apo-2 ligand gene induces tumor cell apoptosis", J IMMUNOL, 165(5), 2000, pp. 2886-2894
63. Thomas, WD; Zhang, XD; Franco, AV; Nguyen, T; Hersey, P
    TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria
    JOURNAL OF IMMUNOLOGY
    
    W.D. Thomas et al., "TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria", J IMMUNOL, 165(10), 2000, pp. 5612-5620
64. Leverkus, M; Neumann, M; Mengling, T; Rauch, CT; Brocker, EB; Krammer, PH; Walczak, H
    Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes
    CANCER RESEARCH
    
    M. Leverkus et al., "Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes", CANCER RES, 60(3), 2000, pp. 553-559
65. Ozoren, N; Kim, KH; Burns, TF; Dicker, DT; Moscioni, AD; El-Deiry, WS
    The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand
    CANCER RESEARCH
    
    N. Ozoren et al., "The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand", CANCER RES, 60(22), 2000, pp. 6259-6265
66. Gong, BD; Almasan, A
    Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells
    CANCER RESEARCH
    
    B.D. Gong e A. Almasan, "Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells", CANCER RES, 60(20), 2000, pp. 5754-5760
67. Hopkins-Donaldson, S; Bodmer, JL; Bourloud, KB; Brognara, CB; Tschopp, J; Gross, N
    Loss of caspase-8 expression in highly malignant human neuroblastoma cellscorrelates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
    CANCER RESEARCH
    
    S. Hopkins-Donaldson et al., "Loss of caspase-8 expression in highly malignant human neuroblastoma cellscorrelates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis", CANCER RES, 60(16), 2000, pp. 4315-4319
68. Mitsiades, N; Poulaki, V; Tseleni-Balafouta, S; Koutras, DA; Stamenkovic, I
    Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
    CANCER RESEARCH
    
    N. Mitsiades et al., "Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand", CANCER RES, 60(15), 2000, pp. 4122-4129
69. Fulda, S; Meyer, E; Debatin, KM
    Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression
    CANCER RESEARCH
    
    S. Fulda et al., "Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression", CANCER RES, 60(14), 2000, pp. 3947-3956
70. Walczak, H; Bouchon, A; Stahl, H; Krammer, PH
    Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2-or Bcl-x(L)-overexpressing chemotherapy-resistant tumor cells
    CANCER RESEARCH
    
    H. Walczak et al., "Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2-or Bcl-x(L)-overexpressing chemotherapy-resistant tumor cells", CANCER RES, 60(11), 2000, pp. 3051-3057
71. Leverkus, M; Walczak, H; McLellan, A; Fries, HW; Terbeck, G; Brocker, EB; Kampgen, E
    Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis
    BLOOD
    
    M. Leverkus et al., "Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis", BLOOD, 96(7), 2000, pp. 2628-2631
72. Wen, JH; Ramadevi, N; Nguyen, D; Perkins, C; Worthington, E; Bhalla, K
    Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells
    BLOOD
    
    J.H. Wen et al., "Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells", BLOOD, 96(12), 2000, pp. 3900-3906
73. Hymowitz, SG; O'Connell, MP; Ultsch, MH; Hurst, A; Totpal, K; Ashkenazi, A; de Vos, AM; Kelley, RF
    A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
    BIOCHEMISTRY
    
    S.G. Hymowitz et al., "A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL", BIOCHEM, 39(4), 2000, pp. 633-640
74. Roth, W; Weller, M
    Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives
    CELLULAR AND MOLECULAR LIFE SCIENCES
    
    W. Roth e M. Weller, "Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives", CELL MOL L, 56(5-6), 1999, pp. 481-506
75. Hymowitz, SG; Christinger, HW; Fuh, G; Ultsch, M; O'Connell, M; Kelley, RF; Ashkenazi, A; de Vos, AM
    Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
    MOLECULAR CELL
    
    S.G. Hymowitz et al., "Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5", MOL CELL, 4(4), 1999, pp. 563-571
76. Walczak, H; Miller, RE; Ariail, K; Gliniak, B; Griffith, TS; Kubin, M; Chin, W; Jones, J; Woodward, A; Le, T; Smith, C; Smolak, P; Goodwin, RG; Rauch, CT; Schuh, JCL; Lynch, DH
    Tumoricidal activity of tumor necrosis factor related apoptosis-inducing ligand in vivo
    NATURE MEDICINE
    
    H. Walczak et al., "Tumoricidal activity of tumor necrosis factor related apoptosis-inducing ligand in vivo", NAT MED, 5(2), 1999, pp. 157-163
77. Johnsen, AC; Haux, J; Steinkjer, B; Nonstad, U; Egeberg, K; Sundan, A; Ashkenazi, A; Espevik, T
    Regulation of Apo-2 ligand/trail expression in NK cells - Involvement in NK cell-mediated cytotoxicity
    CYTOKINE
    
    A.C. Johnsen et al., "Regulation of Apo-2 ligand/trail expression in NK cells - Involvement in NK cell-mediated cytotoxicity", CYTOKINE, 11(9), 1999, pp. 664-672
78. Mori, S; Murakami-Mori, K; Nakamura, S; Ashkenazi, A; Bonavida, B
    Sensitization of AIDS Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D
    JOURNAL OF IMMUNOLOGY
    
    S. Mori et al., "Sensitization of AIDS Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D", J IMMUNOL, 162(9), 1999, pp. 5616-5623
79. Ashkenazi, A; Pai, RC; Fong, S; Leung, S; Lawrence, DA; Masters, SA; Blackie, C; Chang, L; McMurtrey, AE; Hebert, A; DeForge, L; Koumenis, IL; Lewis, D; Harris, L; Bussiere, J; Koeppen, H; Shahrokh, Z; Schwall, RH
    Safety and antitumor activity of recombinant soluble Apo2 ligand
    JOURNAL OF CLINICAL INVESTIGATION
    
    A. Ashkenazi et al., "Safety and antitumor activity of recombinant soluble Apo2 ligand", J CLIN INV, 104(2), 1999, pp. 155-162
80. Costanzo, A; Guiet, C; Vito, P
    c-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappa B
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    A. Costanzo et al., "c-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappa B", J BIOL CHEM, 274(29), 1999, pp. 20127-20132
81. Lee, SH; Shin, MS; Kim, HS; Lee, HK; Park, WS; Kim, SY; Lee, JH; Han, SY; Park, JY; Oh, RR; Jang, JJ; Han, JY; Lee, JY; Yoo, NJ
    Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
    CANCER RESEARCH
    
    S.H. Lee et al., "Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers", CANCER RES, 59(22), 1999, pp. 5683-5686
82. Roth, W; Isenmann, S; Naumann, U; Kugler, S; Bahr, M; Dichgans, J; Ashkenazi, A; Weller, M
    Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    
    W. Roth et al., "Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity", BIOC BIOP R, 265(2), 1999, pp. 479-483
83. Darnay, BG; Aggarwal, BB
    Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors
    ANNALS OF THE RHEUMATIC DISEASES
    
    B.G. Darnay e B.B. Aggarwal, "Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors", ANN RHEUM D, 58, 1999, pp. 2-13
84. Rieger, J; Ohgaki, H; Kleihues, P; Weller, M
    Human astrocytic brain tumors express AP02L/TRAIL
    ACTA NEUROPATHOLOGICA
    
    J. Rieger et al., "Human astrocytic brain tumors express AP02L/TRAIL", ACT NEUROP, 97(1), 1999, pp. 1-4
85. ASHKENAZI A; DIXIT VM
    DEATH RECEPTORS - SIGNALING AND MODULATION
    Science
    
    A. Ashkenazi e V.M. Dixit, "DEATH RECEPTORS - SIGNALING AND MODULATION", Science, 281(5381), 1998, pp. 1305-1308
86. KOTHNYWILKES G; KULMS D; POPPELMANN B; LUGER TA; KUBIN M; SCHWARZ T
    INTERLEUKIN-1 PROTECTS TRANSFORMED KERATINOCYTES FROM TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND
    The Journal of biological chemistry
    
    G. Kothnywilkes et al., "INTERLEUKIN-1 PROTECTS TRANSFORMED KERATINOCYTES FROM TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND", The Journal of biological chemistry, 273(44), 1998, pp. 29247-29253