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    1. Rosenecker, J; Eichler, I; Barmeier, H; von der Hardt, H
      Diabetes mellitus and cystic fibrosis: Comparison of clinical parameters in patients treated with insulin versus oral glucose-lowering agents

      PEDIATRIC PULMONOLOGY
    2. Caraco, Y; Muszkat, M; Wood, AJJ
      Phenytoin metabolic ratio: a putative marker of CYP2C9 activity in vivo

      PHARMACOGENETICS
    3. Tang, CY; Shou, MG; Rushmore, TH; Mei, Q; Sandhu, P; Woolf, EJ; Rose, MJ; Gelmann, A; Greenberg, HE; De Lepeleire, I; Van Hecken, A; De Schepper, PJ; Ebel, DL; Schwartz, JI; Rodrigues, AD
      In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelicvariant forms of human liver microsomal cytochrome P4502C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics

      PHARMACOGENETICS
    4. Nishimura, N; Naora, K; Hirano, H; Iwamoto, K
      Changes in the dissolution of tolbutamide by a traditional Chinese medicine, Sho-saiko-to (Xiao Chaihu Tang)

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    5. Seki, Y; Sato, K; Ohtsu, H; Akiba, Y
      Persistent hypoglycemia is induced by tolbutamide administration in broiler chickens fed a low-carbohydrate diet

      DOMESTIC ANIMAL ENDOCRINOLOGY
    6. Ahsan, F; Arnold, JJ; Meezan, E; Pillion, DJ
      Mutual inhibition of the insulin absorption-enhancing properties of dodecylmaltoside and dimethyl-beta-cyclodextrin following nasal administration

      PHARMACEUTICAL RESEARCH
    7. Suihko, E; Korhonen, O; Jarvinen, T; Ketolainen, J; Jahro, P; Laine, E; Paronen, P
      Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    8. Veiga, F; Fernandes, C; Maincent, P
      Influence of the preparation method on the physicochemical properties of tolbutamide/cyclodextrin binary systems

      DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
    9. Goldstein, JA
      Clinical relevance of genetic polymorphisms in the human CYP2C subfamily

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    10. Scordo, MG; Aklillu, E; Yasar, U; Dahl, ML; Spina, E; Ingelman-Sundberg, M
      Genetic polymorphism of cytochrome P4502C9 in a Caucasian and a black African population

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    11. Abad, S; Moachon, L; Blanche, P; Bavoux, F; Sicard, D; Salmon-Ceron, D
      Possible interaction between gliclazide, fluconazole and sulfamethoxazole resulting in severe hypoglycaemia

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    12. Shen, ZP; Nishimura, M; Tsuura, Y; Fujimoto, S; Mukai, E; Yamada, Y; Seino, Y
      Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets

      DIABETES RESEARCH AND CLINICAL PRACTICE
    13. Saydah, SH; Eberhardt, MS; Loria, CM; Brancati, FL
      Subclinical stales of glucose intolerance and risk of death in the US

      DIABETES CARE
    14. Moran, A; Phillips, J; Milla, C
      Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes

      DIABETES CARE
    15. Kim, JS; Nafziger, AN; Gaedigk, A; Dickmann, LJ; Rettie, AE; Bertino, JS
      Effects of oral vitamin K on S- and R-Warfarin pharmacokinetics and pharmacodynamics: Enhanced safety of warfarin as a CYP2C9 probe

      JOURNAL OF CLINICAL PHARMACOLOGY
    16. Yasar, U; Tybring, G; Hidestrand, M; Oscarson, M; Ingelman-Sundberg, M; Dahl, ML; Eliasson, E
      Role of CYP2C9 polymorphism in losartan oxidation

      DRUG METABOLISM AND DISPOSITION
    17. Palamanda, JR; Casciano, CN; Norton, LA; Clement, RP; Favreau, LV; Lin, CC; Nomeir, AA
      Mechanism-based inactivation of CYP2D6 by 5-fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine

      DRUG METABOLISM AND DISPOSITION
    18. Andersson, TB; Sjoberg, H; Hoffmann, KJ; Boobis, AR; Watts, P; Edwards, RJ; Lake, BG; Price, RJ; Renwick, AB; Gomez-Lechon, MJ; Castell, JV; Ingelman-Sundberg, M; Hidestrand, M; Goldfarb, PS; Lewis, DFV; Corcos, L; Guillouzo, A; Taavitsainen, P; Pelkonen, O
      An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant

      DRUG METABOLISM AND DISPOSITION
    19. Taavitsainen, P; Juvonen, R; Pelkonen, O
      In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene

      DRUG METABOLISM AND DISPOSITION
    20. Easterbrook, J; Lu, C; Sakai, Y; Li, AP
      Effects of organic solvents on the activities of cytochrome P450 isoforms,UDP-dependent glucuronyl transferase, and phenol sulfotransferase in humanhepatocytes

      DRUG METABOLISM AND DISPOSITION
    21. Krausz, KW; Goldfarb, I; Buters, JTM; Yang, TJ; Gonzalez, FJ; Gelboin, HV
      Monoclonal antibodies specific and inhibitory to human cytochromes P4502C8, 2C9, and 2C19

      DRUG METABOLISM AND DISPOSITION
    22. Pelkonen, O; Myllynen, P; Taavitsainen, P; Boobis, AR; Watts, P; Lake, BG; Price, RJ; Renwick, AB; Gomez-Lechon, MJ; Castell, JV; Ingelman-Sundberg, M; Hidestrand, M; Guillouzo, A; Corcos, L; Goldfarb, PS; Lewis, DFV
      Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems

      XENOBIOTICA
    23. Giancarlo, GM; Venkatakrishnan, K; Granda, BW; von Moltke, LL; Greenblatt, DJ
      Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    24. Nishimura, N; Naora, K; Hirano, H; Iwamoto, K
      Effects of Sho-saiko-to (Xiao Chai Hu Tang), a Chinese traditional medicine, on the gastric function and absorption of tolbutamide in rats

      YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
    25. Lechuga, CG; Carrillo, JJ; Sanchez-Gutierrez, JC; Feliu, JE
      Decreased responsiveness of gluconeogenesis to the modulation by sulfonylureas in hepatocytes isolated from obese (fa/fa) zucker rats

      LIFE SCIENCES
    26. Barg, S; Huang, R; Eliasson, L; Nelson, DJ; Obermuller, S; Rorsman, P; Thevenod, F; Renstrom, E
      Priming of insulin granules for exocytosis by granular Cl- uptake and acidification

      JOURNAL OF CELL SCIENCE
    27. Guo, LQ; Taniguchi, M; Chen, QY; Baba, K; Yamazoe, Y
      Inhibitory potential of herbal medicines on human cytochrome P450-mediatedoxidation: Properties of Umbelliferous or Citrus crude drugs and their relative prescriptions

      JAPANESE JOURNAL OF PHARMACOLOGY
    28. Elmi, A; Idahl, LA; Sehlin, J
      Modulation of islet ATP content by inhibition or stimulation of the Na+/K+pump

      EUROPEAN JOURNAL OF PHARMACOLOGY
    29. Lawrence, CL; Proks, P; Rodrigo, GC; Jones, P; Hayabuchi, Y; Standen, NB; Ashcroft, FM
      Gliclazide produces high-affinity block of K-ATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells

      DIABETOLOGIA
    30. Niemi, M; Backman, JT; Neuvonen, M; Laitila, J; Neuvonen, PJ; Kivisto, KT
      Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    31. Yu, KS; Yim, DS; Cho, JY; Park, SS; Park, JY; Lee, KH; Jang, IJ; Yi, SY; Bae, KS; Shin, SG
      Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    32. Veiga, FJB; Fernandes, CM; Carvalho, RA; Geraldes, CFGC
      Molecular modelling and H-1-NMR: Ultimate tools for the investigation of tolbutamide : beta-cyclodextrin and tolbutamide : hydroxypropyl-beta-cyclodextrin complexes

      CHEMICAL & PHARMACEUTICAL BULLETIN
    33. Jonkers, FC; Guiot, Y; Rahier, J; Henquin, JC
      Tolbutamide stimulation of pancreatic beta-cells involves both cell recruitment and increase in the individual Ca2+ response

      BRITISH JOURNAL OF PHARMACOLOGY
    34. Reimann, F; Proks, P; Ashcroft, FM
      Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel

      BRITISH JOURNAL OF PHARMACOLOGY
    35. Lenzen, S; Peckmann, T
      Effects of tolbutamide and N-benzoyl-D-phenylalanine (NBDP) on the regulation of [Ca2+](i) oscillations in mouse pancreatic islets

      BIOCHEMICAL PHARMACOLOGY
    36. Ha-Duong, NT; Marques-Soares, C; Dijols, S; Sari, MA; Dansette, PM; Mansuy, D
      Interaction of new sulfaphenazole derivatives with human liver cytochrome P4502Cs: Structural determinants required for selective recognition by CYP2C9 and for inhibition of human CYP2Cs

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    37. Allen, JR; Williams, JD; Burinsky, DJ; Cole, SR
      Isolation of the components of a complex mixture by means of column switching for their enhanced detection by mass spectrometry

      JOURNAL OF CHROMATOGRAPHY A
    38. Liapis, P; Pass, GJ; McKinnon, RA; Stupans, I
      Characterisation of tolbutamide hydroxylase activity in the common brushtail possum, (Trichosurus vulpecula) and koala (Phascolarctos cinereus): inhibition by the Eucalyptus terpene 1,8-cineole

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
    39. Lindblad, U; Melander, A
      Sulphonylurea dose-response relationships: relation to clinical practice

      DIABETES OBESITY & METABOLISM
    40. Ashcroft, FM; Gribble, FM
      Tissue-specific effects of sulfonylureas lessons from studies of cloned K-ATP channels

      JOURNAL OF DIABETES AND ITS COMPLICATIONS
    41. Veiga, MD; Ahsan, F
      Influence of surfactants (present in the dissolution media) on the releasebehaviour of tolbutamide from its inclusion complex with beta-cyclodextrin

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    42. Taavitsainen, P; Anttila, M; Nyman, L; Karnani, H; Salonen, JS; Pelkonen, O
      Selegiline metabolism and cytochrome P450 enzymes: In vitro study in humanliver microsomes

      PHARMACOLOGY & TOXICOLOGY
    43. Brockhaus, J; Deitmer, JW
      Developmental downregulation of ATP-sensitive potassium conductance in astrocytes in situ

      GLIA
    44. Suihko, E; Poso, A; Korhonen, O; Gynther, J; Ketolainen, J; Paronen, P
      Deformation behaviors of tolbutamide, hydroxypropyl-beta-cyclodextrin, andtheir dispersions

      PHARMACEUTICAL RESEARCH
    45. Kanamitsu, S; Ito, K; Sugiyama, Y
      Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: Use of maximum unbound concentration of inhibitor at the inlet to the liver

      PHARMACEUTICAL RESEARCH
    46. Veiga, F; Fernandes, C; Teixeira, F
      Oral bioavailability and hypoglycaemic activity of tolbutamide/cyclodextrin inclusion complexes

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    47. Jiao, JH; Baumann, P; Baron, A; Roatti, A; Pence, RA; Baertschi, AJ
      Sulfonylurea receptor ligands modulate stretch-induced ANF secretion in rat atrial myocyte culture

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    48. Ko, JW; Desta, Z; Soukhova, NV; Tracy, T; Flockhart, DA
      In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    49. Cuttle, L; Munns, AJ; Hogg, NA; Scott, JR; Hooper, WD; Dickinson, RG; Gillam, EMJ
      Phenytoin metabolism by human cytochrome P450: Involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation

      DRUG METABOLISM AND DISPOSITION
    50. Gantenbein, M; Attolini, L; Bruguerolle, B; Villard, PH; Puyoou, F; Durand, A; Lacarelle, B; Hardwigsen, J; Le-Treut, YP
      Oxidative metabolism of bupivacaine into pipecolylxylidine in humans is mainly catalyzed by CYP3A

      DRUG METABOLISM AND DISPOSITION
    51. Thijssen, HH; Flinois, JP; Beaune, PH
      Cytochrome P4502C9 is the principal catalyst of racemic acenocoumarol hydroxylation reactions in human liver microsomes

      DRUG METABOLISM AND DISPOSITION
    52. Komatsu, T; Yamazaki, H; Asahi, S; Gillam, EMJ; Guengerich, FP; Nakajima, M; Yokoi, T
      Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: Roles of cytochromes P4502C9, 2C19, and 3A4

      DRUG METABOLISM AND DISPOSITION
    53. Krausz, KW; Goldfarb, I; Yang, TJ; Gonzalez, FJ; Gelboin, HV
      An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys

      XENOBIOTICA
    54. Emoto, C; Yamazaki, H; Yamasaki, S; Shimada, N; Nakajima, M; Yokoi, T
      Use of everted sacs of mouse small intestine as enzyme sources for the study of drug oxidation activities in vitro

      XENOBIOTICA
    55. Marinelli, S; Bernardi, G; Giacomini, P; Mercuri, NB
      Pharmacological identification of the K+ currents mediating the hypoglycemic hyperpolarization of rat midbrain dopaminergic neurones

      NEUROPHARMACOLOGY
    56. Jung, O; Englert, HC; Jung, W; Gogelein, H; Scholkens, BA; Busch, AE; Linz, W
      The K-ATP channel blocker HMR 1883 does not abolish the benefit of ischemic preconditioning on myocardial infarct mass in anesthetized rabbits

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    57. Gribble, FM; Ashcroft, FM
      Sulfonylurea sensitivity of adenosine triphosphate-sensitive potassium channels from beta cells and extrapancreatic tissues

      METABOLISM-CLINICAL AND EXPERIMENTAL
    58. Gopel, SO; Kanno, T; Barg, S; Rorsman, P
      Patch-clamp characterisation of somatostatin-secreting delta-cells in intact mouse pancreatic islets

      JOURNAL OF PHYSIOLOGY-LONDON
    59. Best, L; Brown, PD; Sheader, EA; Yates, AP
      Selective inhibition of glucose-stimulated beta-cell activity by an anion channel inhibitor

      JOURNAL OF MEMBRANE BIOLOGY
    60. Ball, AJ; Flatt, PR; McClenaghan, NH
      Desensitization of sulphonylurea- and nutrient-induced insulin secretion following prolonged treatment with glibenclamide

      EUROPEAN JOURNAL OF PHARMACOLOGY
    61. Ortsater, H; Liss, P; Lund, PE; Akerman, KEO; Bergsten, P
      Oscillations in oxygen tension and insulin release of individual pancreatic ob/ob mouse islets

      DIABETOLOGIA
    62. Markworth, E; Schwanstecher, C; Schwanstecher, M
      ATP(4-) mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites

      DIABETES
    63. Koriyama, N; Kakei, M; Nakazaki, M; Yaekura, K; Ichinari, K; Gong, Q; Morimitsu, S; Yada, T; Tei, C
      PIP2 and ATP cooperatively prevent cytosolic Ca2+-induced modification of ATP-sensitive K+ channels in rat pancreatic beta-cells

      DIABETES
    64. Veiga, MD; Ahsan, F
      Study of tolbutamide-hydroxypropyl-gamma-cyclodextrin interaction in solution and solid state

      CHEMICAL & PHARMACEUTICAL BULLETIN
    65. Kimura, K; Hirayama, F; Arima, H; Uekama, K
      Effects of aging on crystallization, dissolution and absorption characteristics of amorphous tolbutamide-2-hydroxypropyl-beta-cyclodextrin complex

      CHEMICAL & PHARMACEUTICAL BULLETIN
    66. Elmi, A; Idahl, LA; Sehlin, J
      Relationships between the Na+/K+ pump and ATP and ADP content in mouse pancreatic islets: effects of meglitinide and glibenclamide

      BRITISH JOURNAL OF PHARMACOLOGY
    67. Engbersen, R; Moons, MM; Wouterse, AC; Dijkman, HB; Kramers, C; Smits, P; Russel, FGM
      Sulphonylurea drugs reduce hypoxic damage in the isolated perfused rat kidney

      BRITISH JOURNAL OF PHARMACOLOGY
    68. Miyamura, A; Kakei, M; Ichinari, K; Okamura, M; Oketani, N; Tei, C
      On the mechanism of ADP-induced alteration of sulphonylurea sensitivity incardiac ATP-sensitive K+ channels

      BRITISH JOURNAL OF PHARMACOLOGY
    69. McClenaghan, NH; Ball, AJ; Flatt, PR
      Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide

      BRITISH JOURNAL OF PHARMACOLOGY
    70. Patane, G; Piro, S; Anello, M; Rabuazzo, AM; Vigneri, R; Purrello, F
      Exposure to glibenclamide increases rat beta cells sensitivity to glucose

      BRITISH JOURNAL OF PHARMACOLOGY
    71. Rodrigues, ARA; Duarte, IDG
      The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K+ channels

      BRITISH JOURNAL OF PHARMACOLOGY
    72. Best, L
      Glucose-sensitive conductances in rat pancreatic beta-cells: contribution to electrical activity

      BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
    73. Medvedovici, A; David, V; Miron, D; Mircioiu, C
      Comparison of two sample preparation methods for a HPLC-DAD assay of Tolbutamide from human plasma

      ANALYTICAL LETTERS
    74. El-Ries, MA; Abou Sekkina, MM
      Thermal stability of gamma-irradiated tolbutamide

      JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
    75. Kidd, RS; Straughn, AB; Meyer, MC; Blaisdell, J; Goldstein, JA; Dalton, JT
      Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele

      PHARMACOGENETICS
    76. Damkier, P; Hansen, LL; Brosen, K
      Rifampicin treatment greatly increases the apparent oral clearance of quinidine

      PHARMACOLOGY & TOXICOLOGY
    77. Eberhardson, M; Grapengiesser, E
      Role of voltage-dependent Na+ channels for rhythmic Ca2+ signalling in glucose-stimulated mouse pancreatic beta-cells

      CELLULAR SIGNALLING
    78. Kimura, K; Hirayama, F; Arima, H; Uekama, K
      Solid-state C-13 nuclear magnetic resonance spectroscopic study on amorphous solid complexes of tolbutamide with 2-hydroxypropyl-alpha- and -beta-cyclodextrins

      PHARMACEUTICAL RESEARCH
    79. Aynacioglu, AS; Brockmoller, J; Bauer, S; Sachse, C; Guzelbey, P; Ongen, Z; Nacak, M; Roots, I
      Frequency of cytochrome P450CYP2C9 variants in a Turkish population and functional relevance for phenytoin

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    80. Baldwin, SJ; Clarke, SE; Chenery, RJ
      Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    81. Carlile, DJ; Hakooz, N; Bayliss, MK; Houston, JB
      Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    82. Gross, AS; Bridge, S; Shenfield, GM
      Pharmacokinetics of tolbutamide in ethnic Chinese

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    83. de Arriba, SG; Franke, H; Pissarek, M; Nieber, K; Illes, P
      Neuroprotection by ATP-dependent potassium channels in rat neocortical brain slices during hypoxia

      NEUROSCIENCE LETTERS
    84. Liu, MT; Seino, S; Kirchgessner, AL
      Identification and characterization of glucoresponsive neurons in the enteric nervous system

      JOURNAL OF NEUROSCIENCE
    85. Agardh, CD; Bjorgell, P; Nilsson-Ehle, P
      The effects of tolbutamide on lipoproteins, lipoprotein lipase and hormone-sensitive lipase

      DIABETES RESEARCH AND CLINICAL PRACTICE
    86. Hansen, LL; Brosen, K
      Quantitative determination of tolbutamide and its metabolites in human plasma and urine by high-performance liquid chromatography and UV detection

      THERAPEUTIC DRUG MONITORING
    87. Riddle, MC
      Overview of current therapeutic options - Session summary

      DIABETES CARE
    88. Rustenbeck, I; Dickel, C; Herrmann, C; Grimmsmann, T
      Mitochondria present in excised patches from pancreatic B-cells may form microcompartments with ATP-dependent potassium channels

      BIOSCIENCE REPORTS
    89. Wang, Y; Unadkat, JD
      Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes

      BIOPHARMACEUTICS & DRUG DISPOSITION
    90. Karol, MD; Locke, CS; Cavanaugh, JH
      Lack of pharmacokinetic interaction between lansoprazole and intravenouslyadministered phenytoin

      JOURNAL OF CLINICAL PHARMACOLOGY
    91. Sandstrom, R; Lennernas, H
      Repeated oral rifampicin decreases the jejunal permeability of R/S-verapamil in rats

      DRUG METABOLISM AND DISPOSITION
    92. Kharasch, ED; Hankins, DC; Jubert, C; Thummel, KE; Taraday, JK
      Lack of single-dose disulfiram effects on cytochrome P-4502C9, 2C19, 2D6, and 3A4 activities: Evidence for specificity toward P-450 2E1

      DRUG METABOLISM AND DISPOSITION
    93. Taguchi, K; Konishi, T; Nishikawa, H; Kitamura, S
      Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid

      XENOBIOTICA
    94. Ochi, H; Ikeda, T
      Sulfonylureas stimulate renin secretion from the perfused kidney of the rat

      NEPHRON
    95. Ueda, K; Komine, J; Matsuo, M; Seino, S; Amachi, T
      Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    96. Dorschner, H; Brekardin, E; Uhde, I; Schwanstecher, C; Schwanstecher, M
      Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure

      MOLECULAR PHARMACOLOGY
    97. Mesdjian, E; Seree, E; Charvet, B; Mirrione, A; Bourgarel-Rey, V; Desobry, A; Barra, Y
      Metabolism of carbamazepine by CYP3A6: A model for in vitro drug interactions studies

      LIFE SCIENCES
    98. Greenhalgh, DJ; Williams, AC; Timmins, P; York, P
      Solubility parameters as predictors of miscibility in solid dispersions

      JOURNAL OF PHARMACEUTICAL SCIENCES
    99. Kawaki, J; Nagashima, K; Tanaka, J; Miki, T; Miyazaki, M; Gonoi, T; Mitsuhashi, N; Nakajima, N; Iwanaga, T; Yano, H; Seino, S
      Unresponsiveness to glibenclamide during chronic treatment induced by reduction of ATP-sensitive K+ channel activity

      DIABETES
    100. McCrea, JB; Cribb, A; Rushmore, T; Osborne, B; Gillen, L; Lo, MW; Waldman, S; Bjornsson, T; Spielberg, S; Goldberg, MR
      Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174

      CLINICAL PHARMACOLOGY & THERAPEUTICS


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Documento generato il 12/08/20 alle ore 00:49:12