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Black tea extract, thearubigin fraction, counteracts the effect of tetanustoxin in mice
EXPERIMENTAL BIOLOGY AND MEDICINE
DNA fusion vaccines against B-cell tumors
TRENDS IN MOLECULAR MEDICINE
Induction of mucosal immune response after intranasal or oral inoculation of mice with Lactococcus lactis producing bovine beta-lactoglobulin
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in therat
NEUROBIOLOGY OF DISEASE
Kindling induces transient fast inhibition in the dentate gyrus-CA3 projection
EUROPEAN JOURNAL OF NEUROSCIENCE
Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression
EUROPEAN JOURNAL OF NEUROSCIENCE
Crystallographic evidence for doxorubicin binding to the receptor-binding site in Clostridium botulinum neurotoxin B
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Tissue-transglutaminase in rat and human brain: Light and electron immunocytochemical analysis and in situ hybridization study
BRAIN RESEARCH BULLETIN
Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy
NEUROSCIENCE
Use of magnetic nanobeads to study intracellular antigen processing
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
Peptide phage display library as source for inhibitors of clostridial neurotoxins
JOURNAL OF PROTEIN CHEMISTRY
Reduced excitatory drive onto interneurons in the dentate gyrus after status epilepticus
JOURNAL OF NEUROSCIENCE
Adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release
JOURNAL OF NEUROSCIENCE
Stages of synapse development defined by dependence on F-actin
JOURNAL OF NEUROSCIENCE
Bordetella bronchiseptica fimbrial protein-enhanced immunogenicity of a Mannheimia haemolytica leukotoxin fragment
VACCINE
Immunological implications of structural mimicry between a dodecapeptide and a carbohydrate moiety
VACCINE
Immunization with recombinant Streptococcus gordonii expressing tetanus toxin fragment C confers protection from lethal challenge in mice
VACCINE
Synaptosomal and vesicular accumulation of L-glutamate, L-aspartate and D-aspartate
NEUROCHEMISTRY INTERNATIONAL
Release of D,L-threo-beta-hydroxyaspartate as a false transmitter from excitatory amino acid-releasing nerve terminals
NEUROCHEMISTRY INTERNATIONAL
Clostridium botulinum neurotoxins act with a wide range of potencies on SH-SY5Y human neuroblastoma cells
NEUROTOXICOLOGY
Surface expression of the conserved C repeat region of streptococcal M6 protein within the Pip bacteriophage I receptor of Lactococcus lactis
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Fusion protein vesicle-associated membrane protein 2 is implicated in IFN-gamma-induced piecemeal degranulation in human eosinophils from atopic individuals
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Neuronal activity and the establishment of normal and epileptic circuits during brain development
BRAIN PLASTICITY AND EPILEPSY
Treatment of G(M2) gangliosidosis: Past experiences, implications, and future prospects
TAY-SACHS DISEASE
Anomalous enhancement of botulinum toxin type A neurotoxicity in the presence of antitoxin
TOXICON
Clostridium botulinum and its neurotoxins: a metabolic and cellular perspective
TOXICON
Botulinum neurotoxin types B and E: purification, limited proteolysis by endoproteinase Glu-C and pepsin, and comparison of their identified cleaved sites relative to the three-dimensional structure of type A neurotoxin
TOXICON
SNARE function analyzed in synaptobrevin/VAMP knockout mice
SCIENCE
Hypertonic enhancement of transmitter release from frog motor nerve terminals: Ca2+ independence and role of integrins
JOURNAL OF PHYSIOLOGY-LONDON
Cleavage of SNAP-25 by botulinum toxin type A requires receptor-mediated endocytosis, pH-dependent translocation, and zinc
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
DNA fusion vaccine designed to induce cytotoxic T cell responses against defined peptide motifs: Implications for cancer vaccines
JOURNAL OF IMMUNOLOGY
The role of zinc binding in the biological activity of botulinum toxin
JOURNAL OF BIOLOGICAL CHEMISTRY
The role of the synaptic protein SNAP-25 in the potency of botulinum neurotoxin type A
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of receptor-mediated signal transduction by Escherichia coli type IIa heat-labile enterotoxin in the polarized human intestinal cellline T84
INFECTION AND IMMUNITY
Black tea extract, thearubigin fraction, counteract the effects of botulinum neurotoxins in mice
BRITISH JOURNAL OF PHARMACOLOGY
High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Site-directed mutagenesis identifies active-site residues of the light chain of botulinum neurotoxin type A
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
High-throughput assays for botulinum neurotoxin proteolytic activity: Serotypes A, B, D, and F
ANALYTICAL BIOCHEMISTRY
Neuromuscular junction
KLINISCHE NEUROPHYSIOLOGIE
Protein degradation in MHC class II antigen presentation: opportunities for immunomodulation
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Cellular abnormalities and synaptic plasticity in seizure disorders of theimmature nervous system
MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS
Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin typeB at 2.0 angstrom resolution
NATURE STRUCTURAL BIOLOGY
Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B
NATURE STRUCTURAL BIOLOGY
The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomesand late endosomes
MOLECULAR BIOLOGY OF THE CELL
Spine loss and other dendritic abnormalities in epilepsy
HIPPOCAMPUS
Stereotypical physiological properties emerge during early neuronal and glial lineage development in the embryonic rat neocortex
CEREBRAL CORTEX
Fermentation, purification, and efficacy of a recombinant vaccine candidate against botulinum neurotoxin type F from Pichia pastoris
PROTEIN EXPRESSION AND PURIFICATION
DNA vaccination using the fragment C of botulinum neurotoxin type A provided protective immunity in mice
JOURNAL OF BIOMEDICAL SCIENCE
Retargeting of adenoviral vectors to neurons using the H-c fragment of tetanus toxin
GENE THERAPY
An example of immunodominance: engagement of synonymous TCR by invariant CDR3 beta
INTERNATIONAL IMMUNOLOGY
Crystallization and preliminary X-ray analysis of Clostridium botulinum neurotoxin type B
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
A conjugate composed of nerve growth factor coupled to a non-toxic derivative of Clostridium botulinum neurotoxin type A can inhibit neurotransmitterrelease in vitro
GROWTH FACTORS
Protective effect of supplemental superoxide dismutase on survival of neuronal cells during starvation - Requirement for cytosolic distribution
JOURNAL OF MOLECULAR NEUROSCIENCE
Role of calcium in neurotransmitter release evoked by alpha-latrotoxin or hypertonic sucrose
NEUROSCIENCE
Development of vaccines for prevention of botulism
BIOCHIMIE
How botulinum and tetanus neurotoxins block neurotransmitter release
BIOCHIMIE
Recombinant derivatives of clostridial neurotoxins as delivery vehicles for proteins and small organic molecules
JOURNAL OF PROTEIN CHEMISTRY
Light chain of botulinum a neurotoxin expressed as an inclusion body from a synthetic gene is catalytically and functionally active
JOURNAL OF PROTEIN CHEMISTRY
DNA immunisation against the CFA/I fimbriae of enterotoxigenic Escherichiacoli (ETEC)
VACCINE
Cloning, expression and evaluation of a recombinant sub-unit vaccine against Clostridium botulinum type F toxin
VACCINE
Inhibition of tetanus toxin fragment C binding to ganglioside G(T1b) by monoclonal antibodies recognizing different epitopes
VACCINE
Delta guaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin
VACCINE
Mechanism of action of clostridial neurotoxins and rational inhibitor design
BIOLOGY OF THE CELL
Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: Dependence on HLA class II restricted T-H response
HUMAN IMMUNOLOGY
Pharmacology of botulinum toxin
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Simple and efficient method for heterologous expression of clostridial proteins
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Sensitivity of embryonic rat dorsal root ganglia neurons to Clostridium botulinum neurotoxins
TOXICON
Identification and characterization of an 18-kilodalton, VAMP-like proteinin suspension-cultured carrot cells
PLANT PHYSIOLOGY
The biochemistry of botulinum toxin type B
NEUROLOGY
SNARE proteins contribute to calcium cooperativity of synaptic transmission
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Acute decrease in net glutamate uptake during energy deprivation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Intrinsic dynamics in neuronal networks. II. Experiment
JOURNAL OF NEUROPHYSIOLOGY
Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: A potential vector for delivering heterologous proteins to neurons
JOURNAL OF NEUROCHEMISTRY
Entrapping of impermeant probes of different size into nonpermeabilized synaptosomes as a method to study presynaptic mechanisms
JOURNAL OF NEUROCHEMISTRY
Disruption of synaptic transmission or clock-gene-product oscillations in circadian pacemaker cells of Drosophila cause abnormal behavioral rhythms
JOURNAL OF NEUROBIOLOGY
The C terminus of SNAP25 is essential for Ca2+-dependent binding of synaptotagmin to SNARE complexes
JOURNAL OF BIOLOGICAL CHEMISTRY
Protective antigen-mediated antibody response against a heterologous protein produced in vivo by Bacillus anthracis
INFECTION AND IMMUNITY
Serotonin transporter phosphorylation modulated by tetanus toxin
FEBS LETTERS
A tetanus toxin sensitive protein other than VAMP 2 is required for exocytosis in the pancreatic acinar cell
FEBS LETTERS
Structure-based sequence alignment for the beta-trefoil subdomain of the clostridial neurotoxin family provides residue level information about the putative ganglioside binding site
FEBS LETTERS
T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity
EUROPEAN JOURNAL OF IMMUNOLOGY
Developmental neuroplasticity and epilepsy
EPILEPSIA
Release of dopamine from human neocortex nerve terminals evoked by different stimuli involving extra- and intraterminal calcium
BRITISH JOURNAL OF PHARMACOLOGY
Tracing uptake of C3dg-conjugated antigen into B cells via complement receptor type 2 (CR2, CD21)
BLOOD
Role of zinc binding in type A botulinum neurotoxin light chain's toxic structure
BIOCHEMISTRY
Spectroscopic analysis of pH-induced changes in the molecular features of type a botulinum neurotoxin light chain
BIOCHEMISTRY
Interaction of SNARE proteins in rat parotid acinar cells
ARCHIVES OF ORAL BIOLOGY
Structural basis for BABIM inhibition of botulinum neurotoxin type B protease
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Attenuated Delta guaBA Salmonella typhi vaccine strain CVD 915 as a live vector utilizing prokaryotic or eukaryotic expression systems to deliver foreign antigens and elicit immune responses
CLINICAL IMMUNOLOGY
Botulinum toxin as a carrier for oral vaccines
CELLULAR AND MOLECULAR LIFE SCIENCES
Fusion of endosomes involved in synaptic vesicle recycling
MOLECULAR BIOLOGY OF THE CELL
Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer
GENE THERAPY
Antigenic and immunogenic properties of totally synthetic peptide-based anti-fertility vaccines
INTERNATIONAL IMMUNOLOGY
DNA vaccines against cancer: From genes to therapy
ANNALS OF ONCOLOGY
What is the cell surface receptor(s) for the different serotypes of botulinum neurotoxin?
JOURNAL OF TOXICOLOGY-TOXIN REVIEWS
Botulinum neurotoxins inhibit regulated exocytosis in many abstract cell types other than neurons
JOURNAL OF TOXICOLOGY-TOXIN REVIEWS
Structure-function relationship of clostridial neurotoxins
JOURNAL OF TOXICOLOGY-TOXIN REVIEWS
Botulinum toxin: pharmacologic actions and therapeutic interest in digestive diseases.
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
SNAP-25 requirement for dendritic growth of hippocampal neurons
JOURNAL OF NEUROSCIENCE RESEARCH
CD4(+) T cell response to factor VIII in hemophilia A, acquired hemophilia, and healthy subjects
THROMBOSIS AND HAEMOSTASIS