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Analysis and quantitation of ceramide
G PROTEIN PATHWAYS: PT C, EFFECTOR MECHANISMS
Analysis of c-Jun N-terminal kinase regulation and function
G PROTEIN PATHWAYS: PT C, EFFECTOR MECHANISMS
Differential display of mRNAs regulated by G-protein signaling
G PROTEIN PATHWAYS: PT C, EFFECTOR MECHANISMS
Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2Cl2 cells
BONE
Time course of the MAPK and PI3-kinase response within 24 h of skeletal muscle overload
JOURNAL OF APPLIED PHYSIOLOGY
Insight into skeletal muscle mechanotransduction: MAPK activation is quantitatively related to tension
JOURNAL OF APPLIED PHYSIOLOGY
Fc epsilon RI-dependent signaling pathways in human mast cells
CLINICAL IMMUNOLOGY
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
EMBO REPORTS
TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation
NATURE CELL BIOLOGY
Mechanisms of epithelial fusion and repair
NATURE CELL BIOLOGY
Signal transduction events elicited by cancer prevention compounds
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Mechanisms of tamoxifen-induced apoptosis
APOPTOSIS
The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs)
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
MST1-JNK promotes apoptosis via caspase-dependent and independent pathways
GENES TO CELLS
The parkinsonian neurotoxin, MPP+ induces phosphorylated c-Jun in dopaminergric neurons of mesencephalic cultures
PARKINSONISM & RELATED DISORDERS
Induction of urokinase-type plasminogen activator by sodium salicylate in a glioblastoma cell strain
FOOD TECHNOLOGY AND BIOTECHNOLOGY
TGF-beta-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Sodium arsenite enhances AP-1 and NF kappa B DNA binding and induces stress protein expression in precision-cut rat lung slices
TOXICOLOGICAL SCIENCES
Helicobacter pylori induces apoptosis in human epithelial gastric cells bystress activated protein kinase pathway
HELICOBACTER
Cyclooxygenase-2 is overexpressed in human cervical cancer
CLINICAL CANCER RESEARCH
The small GTPase Rac suppresses apoptosis caused by serum deprivation in fibroblasts
MOLECULAR MEDICINE
Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK
MOLECULAR MEDICINE
Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFN gamma-mediated B cell depletion
IMMUNITY
GADD45 gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector T(H)1 cells
IMMUNITY
Transforming growth factor-beta(1) induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-jun-NH2-terminal kinase-dependent pathway
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
TGF-beta signaling in tumor suppression and cancer progression
NATURE GENETICS
TGF-beta and colorectal carcinogenesis
MICROSCOPY RESEARCH AND TECHNIQUE
Modulation of cell-substrate adhesion by arachidonic acid: Lipoxygenase regulates cell spreading and ERK1/2-inducible cyclooxygenase regulates cell migration in NIH-3T3 fibroblasts
MOLECULAR BIOLOGY OF THE CELL
Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation
MOLECULAR BIOLOGY OF THE CELL
Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1
MOLECULAR BIOLOGY OF THE CELL
Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation
MOLECULAR BIOLOGY OF THE CELL
Transient activation of c-Jun NH2-terminal kinase by growth factors influences survival but not apoptosis of human thyrocytes
THYROID
Involvement of DNA-dependent protein kinase in regulation of stress-induced JNK activation
DNA AND CELL BIOLOGY
Targeting endothelial cells overexpressing VEGFR-2: Selective toxicity of Shiga-like toxin-VEGF fusion proteins
BIOCONJUGATE CHEMISTRY
One-year inhibition of tumor necrosis factor-alpha: a major success or a larger puzzle?
CURRENT OPINION IN RHEUMATOLOGY
p38 MAP kinase negatively regulates cyclin D1 expression in airway smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Cdc42, but not RhoA, regulates cyclin D1 expression in bovine tracheal myocytes
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Explanted glomeruli: Utility and limitations
EXPERIMENTAL NEPHROLOGY
The Ste20 group kinases as regulators of MAP kinase cascades
TRENDS IN CELL BIOLOGY
Effects of prolactin on signal transduction and gene expression: possible relevance for systemic lupus erythematosus
LUPUS
The JNK phosphatase M3/6 is inhibited by protein-damaging stress
CURRENT BIOLOGY
Downregulation of Jun kinase signaling in the amnioserosa is essential fordorsal closure of the Drosophila embryo
CURRENT BIOLOGY
Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice
NEUROMUSCULAR DISORDERS
c-Jun N-terminal kinase activation in hippocampal CAI region was involved in ischemic injury
NEUROREPORT
Extracellular signal-regulated kinase and c-Jun N-terminal protein kinase in ischemic tolerance
NEUROREPORT
Genetic control of skeletal development
CURRENT OPINION IN GENETICS & DEVELOPMENT
Anoikis mechanisms
CURRENT OPINION IN CELL BIOLOGY
CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways
INTERNATIONAL IMMUNOLOGY
Signaling events following chemokine receptor ligation in human dendritic cells at different developmental stages
INTERNATIONAL IMMUNOLOGY
Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation
EUROPEAN JOURNAL OF NEUROSCIENCE
B lymphocyte activation by contact-mediated interactions with T lymphocytes
CURRENT OPINION IN IMMUNOLOGY
MAP-kinase signaling pathways in T cells
CURRENT OPINION IN IMMUNOLOGY
PKC delta mediates ionizing radiation-induced activation of c-Jun NH2-terminal kinase through MKK7 in human thyroid cells
ONCOGENE
NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps
ONCOGENE
MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway
ONCOGENE
Functions of the adapter protein Cas: signal convergence and the determination of cellular responses
ONCOGENE
Tumor necrosis factor receptor-associated factors (TRAFs)
ONCOGENE
NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B
ONCOGENE
Drosophila AP-1: lessons from an invertebrate
ONCOGENE
Jun, the oncoprotein
ONCOGENE
AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration
ONCOGENE
Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes
ONCOGENE
Transforming G proteins
ONCOGENE
Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK)
DEVELOPMENT
Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo
DEVELOPMENT
Drosophila puckered regulates Fos/Jun levels during follicle cell morphogenesis
DEVELOPMENT
Role of receptor activator of nuclear factor-kappa B ligand and osteoprotegerin in bone cell biology
JOURNAL OF MOLECULAR MEDICINE-JMM
Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2+ signaling
MECHANISMS OF DEVELOPMENT
The role of the Drosophila TAK homologue dTAK during development
MECHANISMS OF DEVELOPMENT
Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p2l(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes
JOURNAL OF DERMATOLOGICAL SCIENCE
Mechanism of the cardioprotective effect of inhibition of the renin-angiotensin system on ischemia/reperfusion-induced myocardial injury
Hypertension research
Apoptosis induction by T-2 toxin: Activation of caspase-9, caspase-3, and DFF-40/CAD through cytosolic release of cytochrome c in HL-60 cells
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Induction of the SAPK activator MIG-6 by the alkylating agent methyl methanesulfonate
MOLECULAR CARCINOGENESIS
The TNF-receptor-associated factor family - Scaffold molecules for cytokine receptors, kinases and their regulators
CELLULAR SIGNALLING
Signalling for survival and death in neurones - The role of stress-activated kinases, JNK and p38
CELLULAR SIGNALLING
The ups and downs of MEK kinase interactions
CELLULAR SIGNALLING
Inactivation of JNK activity by mitogen-activated protein kinase phosphatase-2 in EAhy926 endothelial cells is dependent upon agonist-specific JNK translocation to the nucleus
CELLULAR SIGNALLING
Transcription activator protein 1 (AP-1) mediates NO-induced apoptosis of adult cardiomyocytes
FASEB JOURNAL
Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process
FREE RADICAL BIOLOGY AND MEDICINE
Glyoxal and methylglyoxal induce aggregation and inactivation of ERK in human endothelial cells
FREE RADICAL BIOLOGY AND MEDICINE
Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells
FREE RADICAL BIOLOGY AND MEDICINE
Mutations in the Drosophila dTAK1 gene reveal a conserved function or MAPKKKs in the control of rel/NF-kappa B-dependent innate immune responses
GENES & DEVELOPMENT
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
GENES & DEVELOPMENT
Ceramide regulates cellular homeostasis via diverse stress signaling pathways
LEUKEMIA
Integrin-mediated differentiation of a pancreatic carcinoma cell line is independent of FAK or MAPK activation levels
PANCREAS
Cross-talk between pro-inflammatory transcription factors and glucocorticoids
IMMUNOLOGY AND CELL BIOLOGY
Role of extracellular signal-regulated protein kinase cascade in macrophage killing of Candida albicans
JOURNAL OF LEUKOCYTE BIOLOGY
Different Toll-like receptor agonists induce distinct macrophage responses
JOURNAL OF LEUKOCYTE BIOLOGY
Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells
JOURNAL OF LEUKOCYTE BIOLOGY
MAP kinase activation in macrophages
JOURNAL OF LEUKOCYTE BIOLOGY
P38 beta MAP kinase protects rat mesangial cells from TNF-alpha-induced apoptosis
JOURNAL OF CELLULAR BIOCHEMISTRY
Constitutive and heat-shock induced expression of Hsp70 mRNA during chicken testicular development and regression
JOURNAL OF CELLULAR BIOCHEMISTRY
JNK phosphorylates the HSF1 transcriptional activation domain: Role of JNKin the regulation of the heat shock response
JOURNAL OF CELLULAR BIOCHEMISTRY
Biomarker analysis demonstrates a hypoxic environment in the castrated ratventral prostate gland
JOURNAL OF CELLULAR BIOCHEMISTRY
Lead exposure activates nuclear factor kappa B, activator protein-1, c-JunN-terminal kinase and caspases in the rat brain
TOXICOLOGY LETTERS
Role of JNK in hypertonic activation of Cl--dependent Na+/H+ exchange in Xenopus oocytes
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Differential MAP kinase activation and Na+/H+ exchanger phosphorylation byH2O2 in rat cardiac myocytes
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Essential role for extracellular Ca2+ in JNK activation by mechanical stretch in bladder smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY