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Ku-deficient yeast strains exhibit alternative states of silencing competence
EMBO REPORTS
Telomerase and breast cancer
BREAST CANCER RESEARCH
Very short telomeres in the peripheral blood of patients with X-linked andautosomal dyskeratosis congenita
BLOOD CELLS MOLECULES AND DISEASES
Very short telomeres in the peripheral blood of patients with X-linked andautosomal dyskeratosis congenita
BLOOD CELLS MOLECULES AND DISEASES
Subtelomeric chromosome rearrangements are detected using an innovative 12-color FISH assay (M-TEL)
NATURE MEDICINE
Organization of telomeres during the cell and life cycles of Trypanosoma brucei
JOURNAL OF EUKARYOTIC MICROBIOLOGY
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association
NATURE GENETICS
Transition between two forms of heterochromatin at plant subtelomeres
CHROMOSOME RESEARCH
From snapshots to moving pictures: new perspectives on nuclear organization
TRENDS IN CELL BIOLOGY
Transcriptional silencing: Replication redux
CURRENT BIOLOGY
SGS1 is required for telomere elongation in the absence of telomerase
CURRENT BIOLOGY
Turning telomeres off and on
CURRENT OPINION IN CELL BIOLOGY
Telomeres and telomerases: intimations of immortality
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas
ONCOGENE
Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres
ONCOGENE
Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors
ONCOGENE
BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection
FREE RADICAL BIOLOGY AND MEDICINE
RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site
GENES & DEVELOPMENT
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
GENES & DEVELOPMENT
Telomerase activation, cellular immortalization and cancer
ANNALS OF MEDICINE
Aging research in Switzerland
EXPERIMENTAL GERONTOLOGY
From cells to organisms: can we learn about aging from cells in culture?
EXPERIMENTAL GERONTOLOGY
Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress
EXPERIMENTAL GERONTOLOGY
Translating basic aging research into geriatric health care
EXPERIMENTAL GERONTOLOGY
Cellular senescence, cancer and aging: the telomere connection
EXPERIMENTAL GERONTOLOGY
Targeted inhibition of telomerase in human cancer: Will it be a double-edged sword?
ONKOLOGIE
Telomeres, replicative senescence and human ageing
MATURITAS
Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)
GENE
Expansion of repetitive DNA into cytogenetically visible elements
CYTOGENETICS AND CELL GENETICS
Telomere formation by Rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombination
MOLECULAR AND CELLULAR BIOLOGY
Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediatedby interactions between integrase and Sir4p
MOLECULAR AND CELLULAR BIOLOGY
Termini of human chromosomes display elevated rates of mitotic recombination
MUTAGENESIS
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
EMBO JOURNAL
Non-homologous end-joining proteins are required for Agrobacterium T-DNA integration
EMBO JOURNAL
Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides
EMBO JOURNAL
Telomere resolution in the Lyme disease spirochete
EMBO JOURNAL
CD28(+) intraepithelial lymphocytes with long telomeres are recruited within the inflamed ileal mucosa in Crohn disease
HUMAN IMMUNOLOGY
Editorial commentary - Aging and systolic hypertension - Cluster patterns and problem-solving strategies to answer the genetic riddle
HYPERTENSION
Excess growth and apoptosis - Is hypertension a case of accelerated aging of cardiovascular cells?
HYPERTENSION
Cause of progression in Duchenne muscular dystrophy: Impaired differentiation more probable than replicative aging
NEUROPEDIATRICS
Visualization of the terminal structure of rice chromosomes 6 and 12 with multicolor FISH to chromosomes and extended DNA fibers
PLANT MOLECULAR BIOLOGY
Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Submicroscopic 8pter deletion, mild mental retardation, and behavioral problems caused by a familial t(8;20)(p23;p13)
AMERICAN JOURNAL OF MEDICAL GENETICS
Direct visualization of telomeric DNA loops in cells by AFM
SURFACE AND INTERFACE ANALYSIS
Switching and signaling at the telomere
CELL
Positions of potential: Nuclear organization and gene expression
CELL
Markers of cell death-activation in lymphocytes of vertically HIV-infectedchildren naive to highly active antiretroviral therapy: The role of age
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Telomere biology in human aging and aging syndromes
MECHANISMS OF AGEING AND DEVELOPMENT
Telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells
MECHANISMS OF AGEING AND DEVELOPMENT
Replicative mosaicism might explain the seeming contradictions in the telomere theory of aging
MECHANISMS OF AGEING AND DEVELOPMENT
Replication dynamics of the yeast genome
SCIENCE
Transcription - Is S phase important for transcriptional silencing?
SCIENCE
Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
NATURE
Opposing effects of Ets and Id proteins on p16(INK4a) expression during cellular senescence
NATURE
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
NATURE
Repression of vaccinia virus Holliday junction resolvase inhibits processing of viral DNA into unit-length genomes
JOURNAL OF VIROLOGY
Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications
JOURNAL OF PATHOLOGY
NMR structure of the hRap1 Myb motif reveals a canonical three-helix bundle lacking the positive surface charge typical of Myb DNA-binding domains
JOURNAL OF MOLECULAR BIOLOGY
Submicroscopic subtelomeric 1qter deletions: a recognisable phenotype?
JOURNAL OF MEDICAL GENETICS
Satellites on the terminal short arm of chromosome 12 (12ps), inherited through several generations in three families: a new variant without phenotypic effect
JOURNAL OF MEDICAL GENETICS
Stability and transition in a DNA tetraplex: A model for telomeres
JOURNAL OF MACROMOLECULAR SCIENCE-PHYSICS
Viral infections induce abundant numbers of senescent CD8 T cells
JOURNAL OF IMMUNOLOGY
Live observation of fission yeast meiosis in recombination-deficient mutants: a study on achiasmate chromosome segregation
JOURNAL OF CELL SCIENCE
Cytoplasmic microtubular system implicated in de novo formation of a Rabl-like orientation of chromosomes in fission yeast
JOURNAL OF CELL SCIENCE
Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability
JOURNAL OF CELL BIOLOGY
Nuclear position leaves its mark on replication timing
JOURNAL OF CELL BIOLOGY
Genomic sequence and transcriptional analysis of a 23-kilobase mycobacterial linear plasmid: Evidence for horizontal transfer and identification of plasmid maintenance systems
JOURNAL OF BACTERIOLOGY
Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development
INTERNATIONAL JOURNAL OF CANCER
Characterization of a maize chromosome 4 centromeric sequence: Evidence for an evolutionary relationship with the B chromosome centromere
GENETICS
Protosilencers in Saccharomyces cerevisiae subtelomeric regions
GENETICS
Sequence and chromosomal context effects on variegated expression of keratin 5/lacZ constructs in stratified epithelia of transgenic mice
GENETICS
Regulation of cellular senescence by p53
EUROPEAN JOURNAL OF BIOCHEMISTRY
Comparative genomic hybridisation in mentally retarded patients with dysmorphic features and a normal karyotype
CLINICAL GENETICS
The flow cytometric analysis of telomere length in antigen-specific CD8(+)T cells during acute Epstein-Barr virus infection
BLOOD
A negative regulator of telomere-length protein TRF1 is associated with interstitial (TTAGGG)n blocks in immortal Chinese hamster ovary cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Dysmorphology and mental retardation: molecular cytogenetic studies in dysmorphic mentally retarded patients
ANNALES DE GENETIQUE
Telomeres and telomerase: Basic science implications for aging
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Cancer development and progression: A non-adaptive process driven by genetic drift
ACTA BIOTHEORETICA
The reactivation of telomerase in squamous cell carcinomas of the head andneck.
LARYNGO-RHINO-OTOLOGIE
The hTERT alpha splice variant is a dominant negative inhibitor of telomerase activity
NEOPLASIA
Bulk cytokine production versus frequency of cytokine-producing cells in HIV1 infection before and during HAART
CLINICAL IMMUNOLOGY
Functional subsets within clonally expanded CD8(+) memory T cells in elderly humans
CLINICAL IMMUNOLOGY
DNA ends: maintenance of chromosome termini versus repair of double strandbreaks
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Telomeres, telomerase, and myc. An update
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptionalsilencing and much more
CURRENT OPINION IN MICROBIOLOGY
Regulation of apoptosis and replicative senescence in CD8+T cell followingacute viral infection
APOPTOSIS
Multiple functions of yeast telomeric heterochromatin
FOOD TECHNOLOGY AND BIOTECHNOLOGY
Telomeres and HIV disease
MICROBES AND INFECTION
Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process
MOLECULAR CELL
Nutrition, oxidative damage, telomere shortening, and cellular senescence:Individual or connected agents of aging?
MOLECULAR GENETICS AND METABOLISM
Telomerase activity and expression and telomere analysis in situ in the course of treatment of childhood leukemias
BLOOD CELLS MOLECULES AND DISEASES
The dynamics of yeast telomeres and silencing proteins through the cell cycle
JOURNAL OF STRUCTURAL BIOLOGY
Ku autoantigen: A multifunctional DNA-binding protein
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
Telomerase: a therapeutic target for the third millennium?
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Genome organization in the human sperm nucleus studied by FISH and confocal microscopy
MOLECULAR REPRODUCTION AND DEVELOPMENT
Cereal chromosome structure, evolution, and pairing
ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY
Role of genetic instability in cell senescence
RUSSIAN JOURNAL OF GENETICS
TAR cloning of the human chromosome 7 short arm in yeast and screening forterminal sequences
RUSSIAN JOURNAL OF GENETICS
Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: Correlation with sensitivity to DNA damaging agents
INTERNATIONAL JOURNAL OF ONCOLOGY
FISHing for mechanisms of cytogenetically defined terminal deletions usingchromosome-specific subtelomeric probes
EUROPEAN JOURNAL OF HUMAN GENETICS