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Immortal and mortal clonal lymphocyte lines from channel catfish: comparison of telomere length, telomerase activity, tumor suppressor and heat shockprotein expression
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
Structure of the telomeric ends of mt DNA, transcriptional analysis and complex I assembly in the dum24 mitochondrial mutant of Chlamydomonas reinhardtii
MOLECULAR GENETICS AND GENOMICS
A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae
MOLECULAR GENETICS AND GENOMICS
Hsp90 levels affect telomere length in yeast
MOLECULAR GENETICS AND GENOMICS
Telomere lengths and telomerase activity in dog tissues: A potential modelsystem to study human telomere and telomerase biology
NEOPLASIA
Telomere shortening and decreased replicative potential, contrasted by continued proliferation of telomerase-positive CD8(+)CD28(lo) T cells in patients with systemic lupus erythematosus
CLINICAL IMMUNOLOGY
G-quadruplex structure can be stable with only some coordination sites being occupied by cations: A six-nanosecond molecular dynamics study
JOURNAL OF PHYSICAL CHEMISTRY B
A bouquet makes ends meet
NATURE REVIEWS MOLECULAR CELL BIOLOGY
An activation-independent role of transcription factors in insulator function
EMBO REPORTS
Stable gene expression from a mammalian artificial chromosome
EMBO REPORTS
Analysis of the constitution of the beer yeast genome by PCR, sequencing and subtelomeric sequence hybridization
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
G-quadruplex DNA structures - Variations on a theme
BIOLOGICAL CHEMISTRY
Mitochondrial single-stranded DNA-binding proteins: in search for new functions
BIOLOGICAL CHEMISTRY
Werner syndrome: genetic and molecular basis of a premature aging disorder
CELLULAR AND MOLECULAR LIFE SCIENCES
Participation theory of aging
BIOGERONTOLOGY
The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo
RNA-A PUBLICATION OF THE RNA SOCIETY
Human bone marrow transplant rejection is associated with telomere cleavage
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Detection of submicroscopic aberrations in patients with unexplained mental retardation by fluorescence in situ hybridization using multiple subtelomeric probes
GENETICS IN MEDICINE
The fission yeast Taz1 protein protects chromosomes from Ku-dependent end-to-end fusions
MOLECULAR CELL
Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system
GENOME RESEARCH
Cloning efficiency and differentiation
NATURE BIOTECHNOLOGY
Cellular senescence after single and repeated balloon catheter denudationsof rabbit carotid arteries
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Functional and dysfunctional roles of quadruplex DNA in cells
CHEMISTRY & BIOLOGY
Apoptosis in T-lymphocyte subsets in human immunodeficiency virus-infectedchildren measured immediately ex vivo and following in vitro activation
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
Cloning of aged animals: A medical model for tissue and organ regeneration
TRENDS IN CARDIOVASCULAR MEDICINE
Multicolor fluorescence in situ hybridization with peptide nucleic acid probes for enumeration of specific chromosomes in human cells
GENES CHROMOSOMES & CANCER
Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse
SEMINARS IN CANCER BIOLOGY
Telomerase activity in cell lines and lymphoma originating from Bloom syndrome
LEUKEMIA & LYMPHOMA
Telomere dynamics in myelodysplastic syndromes and acute leukemic transformation
LEUKEMIA & LYMPHOMA
Isolation and characterization of two genes encoding ubiquitin fused to a ribosomal protein of 53 amino acids in rice
DNA SEQUENCE
Dysregulation of telomerase activity and expression in lymphokine-activated killer cells from advanced cancer patients: Possible involvement in cancer-associated immunosuppression mechanism
ONCOLOGY REPORTS
Expression of telomeric repeat binding factor 1 and 2 and TRF1-interactingnuclear protein 2 in human gastric carcinomas
INTERNATIONAL JOURNAL OF ONCOLOGY
Impaired telomere regulation mechanism by TRF1 (telomere-binding protein),but not TRF2 expression, in acute leukemia cells
INTERNATIONAL JOURNAL OF ONCOLOGY
A novel automated strategy for screening cryptic telomeric rearrangements in children with idiopathic mental retardation
EUROPEAN JOURNAL OF HUMAN GENETICS
Genetic mapping of telomere-associated sequences in soybean (Glycine max)
PROGRESS IN NATURAL SCIENCE
The changes in telomerase activity and telomere length in HeLa cells undergoing apoptosis induced by sodium butyrate
CHINESE SCIENCE BULLETIN
Asynchronous chromosome pairing in male meiosis of the rat (Rattus norvegicus)
CHROMOSOME RESEARCH
Chromosome healing by addition of telomeric repeats in wheat occurs duringthe first mitotic divisions of the sporophyte and is a gradual process
CHROMOSOME RESEARCH
Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes
HUMAN MOLECULAR GENETICS
Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location
HUMAN MOLECULAR GENETICS
The Pif1p subfamily of helicases: region-specific DNA helicases?
TRENDS IN CELL BIOLOGY
Loss and recovery of Arabidopsis-type telomere repeat sequences 5 '-(TTTAGGG)(n)-3 ' in the evolution of a major radiation of flowering plants
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
The rate of terminal nucleotide loss from a telomere of the mosquito Anopheles gambiae
INSECT MOLECULAR BIOLOGY
Biology of human papillomaviruses
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
Chromosomal boundaries in S-cerevisiae
CURRENT OPINION IN GENETICS & DEVELOPMENT
Building 'validated' mouse models of human cancer
CURRENT OPINION IN CELL BIOLOGY
Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalitiesand rapid loss of viability
ONCOGENE
Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas
ONCOGENE
The C-elegans maternal-effect gene clk-2 is essential for embryonic development, encodes a protein homologous to yeast Tel2p and affects telomere length
DEVELOPMENT
Molecular operations for DNA processing in hypotrichous ciliates
EUROPEAN JOURNAL OF PROTISTOLOGY
Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells
CANCER GENE THERAPY
Shortened telomere length is demonstrated in T-cell subsets together with a pronounced increased telomerase activity in CD4 positive T cells from blood of patients with mycosis fungoides and parapsoriasis
EXPERIMENTAL DERMATOLOGY
Multiple manifestations of X-ray-induced genomic instability in Chinese hamster ovary (CHO) cells
MOLECULAR CARCINOGENESIS
Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension
FASEB JOURNAL
RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site
GENES & DEVELOPMENT
C-elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint
GENES & DEVELOPMENT
Cdc13 both positively and negatively regulates telomere replication
GENES & DEVELOPMENT
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
GENES & DEVELOPMENT
The set1 Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes
GENES & DEVELOPMENT
Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C-elegans chk-2
GENES & DEVELOPMENT
Terminal proteins essential for the replication of linear plasmids and chromosomes in Streptomyces
GENES & DEVELOPMENT
Two telomerase reverse transcriptases (TERTs) expressed in Candida albicans
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
Identification of differentially expressed genes in human memory (CD45RO(+)) CD4(+) T lymphocytes
IMMUNOLOGICAL INVESTIGATIONS
Human clones may be closer than we think
M S-MEDECINE SCIENCES
Memory and forgetfulness of cloned mammals
M S-MEDECINE SCIENCES
Isolation of a Candida glabrata homologue of RAP1, a regulator of transcription and telomere function in Saccharomyces cereviciae
YEAST
Biological timing and the clock metaphor: Oscillatory and hourglass mechanisms
CHRONOBIOLOGY INTERNATIONAL
Non-disruptive PNA-FISH protocol for formalin-fixed and paraffin-embedded tissue sections
BIOTECHNIQUES
A novel topoisomerase II poison GL331 preferentially induces DNA cleavage at (C/G)T sites and can cause telomere DNA damage
PHARMACEUTICAL RESEARCH
The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells
EXPERIMENTAL GERONTOLOGY
The programmed death phenomena, aging, and the Samurai law of biology
EXPERIMENTAL GERONTOLOGY
Stress, DNA damage and ageing - an integrative approach
EXPERIMENTAL GERONTOLOGY
From cells to organisms: can we learn about aging from cells in culture?
EXPERIMENTAL GERONTOLOGY
Cellular senescence, cancer and aging: the telomere connection
EXPERIMENTAL GERONTOLOGY
Telomeres at the chromosome X-p might be critical in limiting the proliferative potential of human cells
EXPERIMENTAL GERONTOLOGY
Estimation of replicative senescence via a population dynamics model of cells in culture
EXPERIMENTAL GERONTOLOGY
Simulated shortening of proliferation-restricting telomeres during clonal proliferation and senescence of human cells
EXPERIMENTAL GERONTOLOGY
Simple and efficient vectors for retrofitting BACs and PACs with mammalianneo(R) and EGFP marker genes
GENE
Subtelomeric rearrangements: results from a study of selected and unselected probands with idiopathic mental retardation and control individuals by using high-resolution G-banding and FISH
HUMAN GENETICS
Submicroscopic terminal deletions and duplications in retarded patients with unclassified malformation syndromes
HUMAN GENETICS
Clinical implications of telomerase detection
HISTOPATHOLOGY
DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways
NUCLEIC ACIDS RESEARCH
Telomeres and replicative senescence: is it only length that counts?
CANCER LETTERS
Classifying by colors: FISH-based genome analysis
CYTOGENETICS AND CELL GENETICS
The human TINF2 gene organisation and chromosomal localization
BIOCHIMIE
Cloning of molluscan telomere DNA with (TTAGGG)n repeat and its chromosomal location in the freshwater snail Biwamelania habei
ZOOLOGICAL SCIENCE
A comparison of normal and leukemic stem cell biology in chronic myeloid leukemia
HEMATOLOGICAL ONCOLOGY
Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break
MOLECULAR AND CELLULAR BIOLOGY
Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53
MOLECULAR AND CELLULAR BIOLOGY
Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast
MOLECULAR AND CELLULAR BIOLOGY
New function of CDC13 in positive telomere length regulation
MOLECULAR AND CELLULAR BIOLOGY
Androgen depletion activates telomerase in the prostate of the nonhuman primate, Macaca mulatta
PROSTATE
Accelerated telomere shortening following allogeneic transplantation is independent of the cell source and occurs within the first year post transplant
BONE MARROW TRANSPLANTATION
Decisive factors: a transcription activator can overcome heterochromatin silencing
BIOESSAYS
Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13
EMBO JOURNAL
T-loops at trypanosome telomeres
EMBO JOURNAL
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression
EMBO JOURNAL
Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
EMBO JOURNAL
T-loop assembly in vitro involves binding of TRF2 near the 3 ' telomeric overhang
EMBO JOURNAL
Sir2p exists in two nucleosome-binding complexes with distinct deacetylaseactivities
EMBO JOURNAL