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La ricerca find articoli where soggetti phrase all words 'TARGETED DISRUPTION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 1629 riferimenti
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    1. Hayashi, T; Faustman, DL
      Genome and hormones: Gender differences in physiology selected contribution: Association of gender-related LMP2 inactivation with autoimmune pathogenesis

      JOURNAL OF APPLIED PHYSIOLOGY
    2. Levin, ER
      Genome and hormones: Gender differences in physiology - Invited review: Cell localization, physiology, and nongenomic actions of estrogen receptors

      JOURNAL OF APPLIED PHYSIOLOGY
    3. Douglas, NC; Jacobs, H; Bothwell, ALM; Hayday, AC
      Defining the specific physiological requirements for c-Myc in T cell development

      NATURE IMMUNOLOGY
    4. Tzachanis, D; Freeman, GJ; Hirano, N; van Puijenbroek, AAFL; Delfs, MW; Berezovskaya, A; Nadler, LM; Boussiotis, VA
      Tob is a negative regulator of activation that is expressed in anergic andquiescent T cells

      NATURE IMMUNOLOGY
    5. Watanabe, G; Kaganoi, J; Imamura, M; Shimada, Y; Itami, A; Uchida, S; Sato, F
      Progression of esophageal carcinoma by loss of EGF-STAT1 pathway

      CANCER JOURNAL
    6. Stoll, SW; Kansra, S; Peshick, S; Fry, DW; Leopold, WR; Wiesen, JF; Sibilia, M; Zhang, T; Werb, Z; Derynck, R; Wagner, EF; Elder, JT
      Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes

      NEOPLASIA
    7. Taniguchi, T; Takaoka, A
      A weak signal for strong responses: Interferon-alpha/beta revisited

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    8. Sharrocks, AD
      The ETS-domain transcription factor family

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    9. Rossant, J; Cross, JC
      Placental development: Lessons from mouse mutants

      NATURE REVIEWS GENETICS
    10. van Gent, DC; Hoeijmakers, JHJ; Kanaar, R
      Chromosomal stability and the DNA double-stranded break connection

      NATURE REVIEWS GENETICS
    11. Rosenfeld, CS; Wagner, JS; Roberts, RM; Lubahn, DB
      Intraovarian actions of oestrogen

      REPRODUCTION
    12. Conley, A; Hinshelwood, M
      Mammalian aromatases

      REPRODUCTION
    13. Roughley, PJ
      Articular cartilage and changes in arthritis - Noncollagenous proteins andproteoglycans in the extracellular matrix of cartilage

      ARTHRITIS RESEARCH
    14. Gravallese, EM; Galson, DL; Goldring, SR; Auron, PE
      The role of TNF-receptor family members and other TRAF-dependent receptorsin bone resorption

      ARTHRITIS RESEARCH
    15. Schepers, U; Kolter, T
      RNA interference: A new way to analyze protein function

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    16. Gerstenfeld, LC; Cho, TJ; Kon, T; Aizawa, T; Cruceta, J; Graves, BD; Einhorn, TA
      Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling

      CELLS TISSUES ORGANS
    17. Shtrichman, R; Samuel, CE
      The role of gamma interferon in antimicrobial immunity

      CURRENT OPINION IN MICROBIOLOGY
    18. Laakso, M
      Insulin resistance and its impact on the approach to therapy of Type 2 diabetes

      INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
    19. Zhang, ZY
      Protein tyrosine phosphatases: prospects for therapeutics

      CURRENT OPINION IN CHEMICAL BIOLOGY
    20. Stanton, JL; Green, DPL
      Meta-analysis of gene expression in mouse preimplantation embryo development

      MOLECULAR HUMAN REPRODUCTION
    21. Saunders, PTK; Sharpe, RM; Williams, K; Macpherson, S; Urquart, H; Irvine, DS; Millar, MR
      Differential expression of oestrogen receptor alpha and beta proteins in the testes and male reproductive system of human and non-human primates

      MOLECULAR HUMAN REPRODUCTION
    22. Butt, AJ; Williams, AC
      IGFBP-3 and apoptosis - a licence to kill ?

      APOPTOSIS
    23. Kumar, S; Fladung, M
      Controlling transgene integration in plants

      TRENDS IN PLANT SCIENCE
    24. Ohtsuki, T; Sakurai, K; Dou, H; Toru, M; Yamakawa-Kobayashi, K; Arinami, T
      Mutation analysis of the NMDAR2B (GRIN2B) gene in schizophrenia

      MOLECULAR PSYCHIATRY
    25. Wajant, H; Scheurich, P
      Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    26. Escalier, D
      Impact of genetic engineering on the understanding of spermatogenesis

      HUMAN REPRODUCTION UPDATE
    27. Tilton, RG; Brock, TA; Dixon, RAF
      Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    28. Chimini, G
      Engulfing by lipids: a matter of taste?

      CELL DEATH AND DIFFERENTIATION
    29. Vemuri, MC; Schiller, E; Naegele, JR
      Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice

      CELL DEATH AND DIFFERENTIATION
    30. Pasqualetti, M; Rijli, FM
      Homeobox gene mutations and brain-stem developmental disorders: learning from knockout mice

      CURRENT OPINION IN NEUROLOGY
    31. Nischik, N; Schade, B; Dytnerska, K; Dlugonska, H; Reichmann, G; Fischer, HG
      Attenuation of mouse-virulent Toxoplasma gondii parasites is associated with a decrease in interleukin-12-inducing tachyzoite activity and reduced expression of actin, catalase and excretory proteins

      MICROBES AND INFECTION
    32. Hofer, S; Rescigno, M; Granucci, F; Citterio, S; Francolini, M; Ricciardi-Castagnoli, P
      Differential activation of NF-kappa B subunits in dendritic cells in response to Gram-negative bacteria and to lipopolysaccharide

      MICROBES AND INFECTION
    33. Weilbaecher, KN; Motyckova, G; Huber, WE; Takemoto, CM; Hemesath, TJ; Xu, Y; Hershey, CL; Dowland, NR; Wells, AG; Fisher, DE
      Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice

      MOLECULAR CELL
    34. Moynahan, ME; Pierce, AJ; Jasin, M
      BRCA2 is required for homology-directed repair of chromosomal breaks

      MOLECULAR CELL
    35. ten Have, A; Breuil, WO; Wubben, JP; Visser, J; van Kan, JAL
      Botrytis cinerea endopolygalacturonase genes are differentially expressed in various plant tissues

      FUNGAL GENETICS AND BIOLOGY
    36. Knudson, CB; Knudson, W
      Cartilage proteoglycans

      SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
    37. Salisbury, JL
      The contribution of epigenetic changes to abnormal centrosomes and genomicinstability in breast cancer

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    38. Watson, CJ
      Stat transcription factors in mammary gland development and tumorigenesis

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    39. Smith, AG
      Embryo-derived stem cells: Of mice and men

      ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
    40. Kriesel, JD; Jones, BB; Hwang, IP; Dahms, KM; Spruance, SL
      Signal transducers and activators of transcription (Stat) are detectable in mouse trigeminal ganglion neurons

      JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
    41. Ausoni, S; Sartore, S
      Cell lineages and tissue boundaries in cardiac arterial and venous poles -Developmental patterns, animal models, and implications for congenital vascular diseases

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    42. Joenje, H; Arwert, F
      Connecting Fanconi anemia to BRCA1

      NATURE MEDICINE
    43. Klein, MA; Kaeser, PS; Schwarz, P; Weyd, H; Xenarios, I; Zinkernagel, RM; Carroll, MC; Verbeek, JS; Botto, M; Walport, MJ; Molina, H; Kalinke, U; Acha-Orbea, H; Aguzzi, A
      Complement facilitates early prion pathogenesis

      NATURE MEDICINE
    44. Cumming, RC; Buchwald, M
      Cellular function of the Fanconi anemia pathway - Reply

      NATURE MEDICINE
    45. Harder, KW; Parsons, LM; Armes, J; Evans, N; Kountouri, N; Clark, R; Quilici, C; Grail, D; Hodgson, GS; Dunn, AR; Hibbs, ML
      Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role of Lyn in the myeloid lineage

      IMMUNITY
    46. Tsitsikov, EN; Laouini, D; Dunn, IF; Sannikova, TY; Davidson, L; Alt, FW; Geha, RS
      TRAF1 is a negative regulator of TNF signaling: Enhanced TNF signaling in TRAF1-deficient mice

      IMMUNITY
    47. Egawa, T; Kawabata, K; Kawamoto, H; Amada, K; Okamoto, R; Fujii, N; Kishimoto, T; Katsura, Y; Nagasawa, T
      The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-B cell growth-stimulating factor

      IMMUNITY
    48. Chen, WJ; Frank, ME; Jin, WW; Wahl, SM
      TGF-beta released by apoptotic T cells contributes to an immunosuppressivemilieu

      IMMUNITY
    49. Gongora, R; Stephan, RP; Zhang, ZX; Cooper, MD
      An essential role for Daxx in the inhibition of B lymphopoiesis by type I interferons

      IMMUNITY
    50. Rossant, J
      Stem cells from the mammalian blastocyst

      STEM CELLS
    51. Bianco, P; Riminucci, M; Gronthos, S; Robey, PG
      Bone marrow stromal stem cells: Nature, biology, and potential applications

      STEM CELLS
    52. Pollock, JL; Westervelt, P; Walter, MJ; Lane, AA; Ley, TJ
      Mouse models of acute promyelocytic leukemia

      CURRENT OPINION IN HEMATOLOGY
    53. Youssoufian, H
      Fanconi anemia and breast cancer: what's the connection?

      NATURE GENETICS
    54. Khanna, KK; Jackson, SP
      DNA double-strand breaks: signaling, repair and the cancer connection

      NATURE GENETICS
    55. Rich, JN; Borton, AJ; Wang, XF
      Transforming growth factor-beta signaling in cancer

      MICROSCOPY RESEARCH AND TECHNIQUE
    56. Brantley, DM; Chen, CL; Muraoka, RS; Bushdid, PB; Bradberry, JL; Kittrell, F; Medina, D; Matrisian, LA; Kerr, LD; Yull, FE
      Nuclear Factor-KB (NF-KB) regulates proliferation and branching in mouse mammary epithelium

      MOLECULAR BIOLOGY OF THE CELL
    57. Bhowmick, NA; Ghiassi, M; Bakin, A; Aakre, M; Lundquist, CA; Engel, ME; Arteaga, CL; Moses, HL
      Transforming growth factor-beta 1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

      MOLECULAR BIOLOGY OF THE CELL
    58. Li, CL; Guo, HM; Xu, XL; Weinberg, W; Deng, CX
      Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning

      DEVELOPMENTAL DYNAMICS
    59. Zeng, X; Gray, M; Stahlman, MT; Whitsett, JA
      TGF-beta 1 perturbs vascular development and inhibits epithelial differentiation in fetal lung in vivo

      DEVELOPMENTAL DYNAMICS
    60. Flanders, KC; Kim, ES; Roberts, AB
      Immunohistochemical expression of Smads 1-6 in the 15-day gestation mouse embryo: Signaling by BMPs and TGF-beta s

      DEVELOPMENTAL DYNAMICS
    61. Kinder, SJ; Loebel, DAF; Tam, PPL
      Allocation and early differentiation of cardiovascular progenitors in the mouse embryo

      TRENDS IN CARDIOVASCULAR MEDICINE
    62. Rakhit, A; Maguire, CT; Wakimoto, H; Gehrmann, J; Li, GK; Kelly, RA; Michel, T; Berul, CI
      In vivo electrophysiologic studies in endothelial nitric oxide synthase (eNOS)-deficient mice

      JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
    63. Dubin, AM
      Of mice and men: In vivo electrophysiologic testing in genetically engineered mice

      JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
    64. Deng, CX; Brodie, SG
      Knockout mouse models and mammary tumorigenesis

      SEMINARS IN CANCER BIOLOGY
    65. Shillingford, JM; Hennighausen, L
      Experimental mouse genetics - answering fundamental questions about mammary gland biology

      TRENDS IN ENDOCRINOLOGY AND METABOLISM
    66. Hemberger, M; Cross, JC
      Genes governing placental development

      TRENDS IN ENDOCRINOLOGY AND METABOLISM
    67. McCauley, LK
      Transgenic mouse models of metabolic bone disease

      CURRENT OPINION IN RHEUMATOLOGY
    68. Rosenfeld, CS; Roberts, RM; Lubahn, DB
      Estrogen receptor- and aromatase-deficient mice provide insight into the roles of estrogen within the ovary and uterus

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    69. Igaz, P; Toth, S; Falus, A
      Biological and clinical significance of the JAK-STAT pathway; lessons fromknockout mice

      INFLAMMATION RESEARCH
    70. Toba, M; Ebara, F; Furuta, H; Matsushimal, Y; Kitagawa, Y; Fujihara, N
      Introduction of DT40 cells into chick embryos

      ASIAN JOURNAL OF ANDROLOGY
    71. Yang, X; Sun, YX; Zhou, J; Huang, PT; Huang, CF; Xu, XL; Li, CL; Gotay, J; Chen, L; Deng, CX
      Establishment of murine Smad5 double knockout ES cells and the studies on their properties

      SCIENCE IN CHINA SERIES C-LIFE SCIENCES
    72. Chen, L; Li, CL; Qiao, WH; Xu, XL; Deng, CX
      A Ser(365)-> Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia

      HUMAN MOLECULAR GENETICS
    73. Raben, N; Lu, N; Nagaraju, K; Rivera, Y; Lee, A; Yan, B; Byrne, B; Meikle, PJ; Umapathysivam, K; Hopwood, JJ; Plotz, PH
      Conditional tissue-specific expression of the acid alpha-glucosidase (GAA)gene in the GAA knockout mice: implications for therapy

      HUMAN MOLECULAR GENETICS
    74. Matsuda, J; Vanier, MT; Saito, Y; Tohyama, J; Suzuki, K; Suzuki, K
      A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse

      HUMAN MOLECULAR GENETICS
    75. Saxton, TM; Cheng, AM; Ong, SH; Lu, Y; Sakai, R; Cross, JC; Pawson, T
      Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis

      CURRENT BIOLOGY
    76. Gurley, KE; Kemp, CJ
      Synthetic lethality between mutation in Atm and DNA-PKcs during murine embryogenesis

      CURRENT BIOLOGY
    77. Wagner, EF; Karsenty, G
      Genetic control of skeletal development

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    78. Finke, D; Kraehenbuhl, JP
      Formation of Peyer's patches

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    79. Rathjen, J; Rathjen, PD
      Mouse ES cells: experimental exploitation of pluripotent differentiation potential

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    80. Aravanis, AM; DeBusschere, BD; Chruscinski, AJ; Gilchrist, KH; Kobilka, BK; Kovacs, GTA
      A genetically engineered cell-based biosensor for functional classification of agents

      BIOSENSORS & BIOELECTRONICS
    81. Ihle, JN
      The Stat family in cytokine signaling

      CURRENT OPINION IN CELL BIOLOGY
    82. Skapek, SX; Lin, SCJ; Jablonski, MM; McKeller, RN; Tan, M; Hu, NP; Lee, EYHP
      Persistent expression of cyclin D1 disrupts normal photoreceptor differentiation and retina development

      ONCOGENE
    83. Govindarajan, V; Overbeek, PA
      Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation

      DEVELOPMENT
    84. Boxem, M; van den Heuvel, S
      lin-35 Rb and cki-1 Cip/Kip cooperate in developmental regulation of G1 progression in C-elegans

      DEVELOPMENT
    85. Zhao, LP; Bakke, M; Krimkevich, Y; Cushman, LJ; Parlow, AF; Camper, SA; Parker, KL
      Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function

      DEVELOPMENT
    86. Manzanares, M; Bel-Vialar, S; Ariza-McNaughton, L; Ferretti, E; Marshall, H; Maconochie, MM; Blasi, F; Krumlauf, R
      Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms

      DEVELOPMENT
    87. Tremblay, KD; Dunn, NR; Robertson, EJ
      Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

      DEVELOPMENT
    88. Zhao, YX; Potter, SS
      Functional specificity of the Hoxa13 homeobox

      DEVELOPMENT
    89. Kaminker, JS; Singh, R; Lebestky, T; Yan, HJ; Banerjee, U
      Redundant function of Runt Domain binding partners, Big brother and Brother, during Drosophila development

      DEVELOPMENT
    90. McClintock, JM; Carlson, R; Mann, DM; Prince, VE
      Consequences of Hox gene duplication in the vertebrates: an investigation of the zebrafish Hox paralogue group 1 genes

      DEVELOPMENT
    91. Sahni, M; Raz, R; Coffin, JD; Levy, D; Basilico, C
      STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2

      DEVELOPMENT
    92. Ishikawa, T; Tamai, Y; Zorn, AM; Yoshida, H; Seldin, MF; Nishikawa, S; Taketo, MM
      Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis

      DEVELOPMENT
    93. Nielsen, M; Bogh, IB; Schmidt, M; Greve, T
      Immunohistochemical localization of estrogen receptor-alpha in sex ducts and gonads of newborn piglets

      HISTOCHEMISTRY AND CELL BIOLOGY
    94. Matsuura, T; Duarte, WR; Cheng, H; Uzawa, K; Yamauchi, M
      Differential expression of decorin and biglycan genes during mouse tooth development

      MATRIX BIOLOGY
    95. Hartmann, U; Maurer, P
      Proteoglycans in the nervous system - the quest for functional roles in vivo

      MATRIX BIOLOGY
    96. Leonard, WJ
      Role of Jak kinases and STATS in cytokine signal transduction

      INTERNATIONAL JOURNAL OF HEMATOLOGY
    97. Ahn, JH; Sposato, P; Kim, SI; Walton, JD
      Molecular cloning and characterization of cel2 from the fungus Cochliboluscarbonum

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    98. Taguchi, N; Ansari, A; Hsu, T; Hashimoto, Y; Dorshkind, K; Shultz, L; Naiki, M; Gershwin, ME
      Increased expression of mXBP-1 (TREB-5) in thymic B cells in New Zealand mice

      JOURNAL OF AUTOIMMUNITY
    99. Kim, H; Ahn, JH; Gorlach, JM; Caprari, C; Scott-Craig, JS; Walton, JD
      Mutational analysis of beta-glucanase genes from the plant-pathogenic fungus Cochliobolus carbonum

      MOLECULAR PLANT-MICROBE INTERACTIONS
    100. Tseng, YT; Kopel, R; Stabila, JP; McGonnigal, BG; Nguyen, TT; Gruppuso, PA; Padbury, JF
      beta-Adrenergic receptors (bAR) regulate cardiomyocyte proliferation during early postnatal life

      FASEB JOURNAL


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Documento generato il 25/05/20 alle ore 04:40:33