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Pasteurella multocida toxin: the mitogenic toxin that stimulates signalling cascades to regulate growth and differentiation
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
Nuclear phospholipase C and signaling
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Lipid messengers as targets for antiangiogenic therapy
CURRENT PHARMACEUTICAL DESIGN
Mechanisms of Bordetella pathogenesis
FRONTIERS IN BIOSCIENCE
Protein kinase C-mediated tyrosine phosphorylation of paxillin and focal adhesion kinase requires cytoskeletal integrity and is uncoupled to mitogen-activated protein kinase activation in human hepatoma cells
JOURNAL OF BIOMEDICAL SCIENCE
Increased activity and nuclear localisation of inositol lipid signal transduction enzymes in rat hepatoma cells
INTERNATIONAL JOURNAL OF ONCOLOGY
Heterogeneity in nuclear transport does not affect the timing of DNA synthesis in quiescent mammalian nuclei induced to replicate in Xenopus egg extracts
CELL PROLIFERATION
Paxillin: a focal adhesion-associated adaptor protein
ONCOGENE
Rho GTPase-dependent transformation by G protein-coupled receptors
ONCOGENE
Increased plasma concentration of adrenomedullin during and after major surgery
SURGERY TODAY
Interleukin-2 activates nuclear phospholipase-C beta by mitogen-activated protein kinase-dependent phosphorylation in human natural killer cells
FASEB JOURNAL
EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
The proliferative response of HT-29 human colon adenocarcinoma cells to bombesin-like peptides
CANCER LETTERS
Bombesin and gastrin releasing peptide increase tyrosine phosphorylation of focal adhesion kinase and paxillin in non-small cell lung cancer cells
CANCER LETTERS
The paradox of smooth muscle physiology
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Biphasic expression of rnrB in Dictyostelium discoideum suggests a direct relationship between cell cycle control and cell differentiation
DIFFERENTIATION
Phosphorylation of nuclear phospholipase C beta 1 by extracellular signal-regulated kinase mediates the mitogenic action of insulin-like growth factor I
MOLECULAR AND CELLULAR BIOLOGY
Neuropeptide-induced androgen independence in prostate cancer cells: Rolesof nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase
MOLECULAR AND CELLULAR BIOLOGY
Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells
BIOCHEMICAL JOURNAL
Proadrenomedullin-derived peptides as autocrine-paracrine regulators of cell growth
HISTOLOGY AND HISTOPATHOLOGY
The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer
PEPTIDES
Biochemical signals and biological responses elicited by the focal adhesion kinase
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Role of the smalt GTP-binding protein rho in epithelial cell migration in the rabbit cornea
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Is there a role for agonist gastrin-releasing peptide receptor radioligands in tumour imaging?
NUCLEAR MEDICINE COMMUNICATIONS
Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 206
Gastrin, CCK, signaling, and cancer
ANNUAL REVIEW OF PHYSIOLOGY
Adrenomedullin from a pheochromocytoma to the eye: Implications of the adrenomedullin research for endocrinology in the 21st century
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
Transcriptional down-regulation of MARCKS gene expression in immortalized hippocampal cells by lithium
JOURNAL OF NEUROCHEMISTRY
Glutamate induces focal adhesion kinase tyrosine phosphorylation and actinrearrangement in heterologous mGluR1-expressing CHO cells via calcium/calmodulin signaling
JOURNAL OF NEUROCHEMISTRY
Pleiotropic effects of Pasteurella multocida toxin are mediated by G(q)-dependent and -independent mechanisms - Involvement of G(q) but not G(11)
JOURNAL OF BIOLOGICAL CHEMISTRY
Molecular basis for selectivity of high affinity peptide antagonists for the gastrin-releasing peptide receptor
JOURNAL OF BIOLOGICAL CHEMISTRY
Bombesin and substance P analogues differentially regulate G-protein coupling to the bombesin receptor - Direct evidence for biased agonism
JOURNAL OF BIOLOGICAL CHEMISTRY
Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of a G protein-activated phosphoinositide 3-kinase in vascular smooth muscle cell nuclei
JOURNAL OF BIOLOGICAL CHEMISTRY
Activator protein-1 transcription factor mediates bombesin-stimulated cyclooxygenase-2 expression in intestinal epithelial cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylationat Tyr-397
JOURNAL OF BIOLOGICAL CHEMISTRY
Escherichia coli cytotoxic necrotizing factor and Pasteurella multocida toxin induce focal adhesion kinase autophosphorylation and Src association
INFECTION AND IMMUNITY
Biological activity of a C-terminal fragment of Pasteurella multocida toxin
INFECTION AND IMMUNITY
Localization of functional domains of the mitogenic toxin of Pasteurella multocida
INFECTION AND IMMUNITY
Re-examination of the mechanisms regulating nuclear inositol lipid metabolism
FEBS LETTERS
Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor
FEBS LETTERS
Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: Dissociation from tyrosine phosphorylation of p130(cas)
EXPERIMENTAL CELL RESEARCH
A bombesin receptor subtype-3 peptide increases nuclear oncogene expression in a MEK-1 dependent manner in human lung cancer cells
EUROPEAN JOURNAL OF PHARMACOLOGY
Gastrin-releasing peptide is a potent vasodilator in humans
CLINICAL PHARMACOLOGY & THERAPEUTICS
Cardiac fibroblasts are major production and target cells of adrenomedullin in the heart in vitro
CARDIOVASCULAR RESEARCH
Lysophosphatidic acid activates the 70-kDa S6 kinase via the lipoxygenase pathway
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Tob-mediated cross-talk between MARCKS phosphorylation and ErbB-2 activation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
A growth factor antagonist as a targeting agent for sterically stabilized liposomes in human small cell lung cancer
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Nuclear localization and signalling activity of inositol lipids
ADVANCES IN MICROANATOMY OF CELLS AND TISSUES, BIOPHYSICAL AND BIOCHEMICALCORRELATES
Nuclear inositides: inconsistent consistencies
CELLULAR AND MOLECULAR LIFE SCIENCES
Identification and chromosomal localisation by fluorescence in situ hybridisation of human gene of phosphoinositide-specific phospholipase C beta(1)
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Adrenomedullin: a new peptidergic regulator of the vascular function
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium
MOLECULAR HUMAN REPRODUCTION
Focal adhesion kinases - Interest in immunoendocrinology, developmental biology, and cancer
ENDOCRINE
Inositide-specific phospholipase C signalling in the nucleus
EUROPEAN JOURNAL OF HISTOCHEMISTRY
Nuclear inositides
EUROPEAN JOURNAL OF HISTOCHEMISTRY
Nuclear envelope signaling-role of phospholipid metabolism
EUROPEAN JOURNAL OF HISTOCHEMISTRY
Intranuclear domains involved in inositol lipid signal transduction
EUROPEAN JOURNAL OF HISTOCHEMISTRY
Cyclooxygenase expression in the gallbladder
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Bradykinin-induced inhibition of cell proliferation and tyrosine kinase activity in rat mesangial cells
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling
MOLECULAR CELL
Gastrin-releasing peptide is a mitogen and a morphogen in murine colon cancer
CELL GROWTH & DIFFERENTIATION
Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Subcellular localization of prostaglandin H synthase-2 in a human amnion cell line: implications for nuclear localized prostaglandin signaling pathways
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
Solid-phase synthesis and biological evaluation of a teleocidin library-discovery of a selective PKC delta down regulator
CHEMISTRY-A EUROPEAN JOURNAL
Properties and functions of diacylglycerol kinases
CELLULAR SIGNALLING
A role for phosphoinositides in tyrosine phosphorylation of p125 focal adhesion kinase in rat pancreatic acini
CELLULAR SIGNALLING
Altered activation of phospholipase D by lysophosphatidic acid and endothelin-1 in mouse embryo fibroblasts lacking phospholipase C-gamma 1
CELLULAR SIGNALLING
Mammalian homolog of the yeast cyclase associated protein, CAP/Srv2p, regulates actin filament assembly
CELL MOTILITY AND THE CYTOSKELETON
Involvement of calmodulin and protein kinase C in cholecystokinin release by bombesin from STC-1 cells
PANCREAS
Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha
JOURNAL OF BONE AND MINERAL RESEARCH
The neuropeptide bombesin modifies the proliferative and invasive properties of tumor cells
M S-MEDECINE SCIENCES
Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells
JOURNAL OF CELLULAR BIOCHEMISTRY
Structure of the murine Pit1 phosphate transporter/retrovirus receptor gene and functional characterization of its promoter region
GENE
Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1neuroblastoma cells
NEUROCHEMICAL RESEARCH
Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Role of Rho in Ca2+-insensitive contraction and paxillin tyrosine phosphorylation in smooth muscle
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Signaling mechanisms regulating bombesin-mediated AP-1 gene induction in the human gastric cancer SIIA
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
The role of Rho in G protein-coupled receptor signal transduction
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesionkinase and paxillin accompanied by their association with cytoskeletal components
NEUROSCIENCE
Characterization of prostaglandin endoperoxide H synthase-1 enzyme expression during differentiation of the megakaryocytic cell line MEG-01
EXPERIMENTAL HEMATOLOGY
Neuromedin B
PROGRESS IN NEUROBIOLOGY
Characterization of the 5'-flanking region of the rat TIS11 gene
MOLECULAR AND CELLULAR BIOCHEMISTRY
Cloning and characterization of the rat TIS11 gene
MOLECULAR AND CELLULAR BIOCHEMISTRY
Functional cross-talk between the cyclic AMP and Jak/STAT signaling pathways in vascular smooth muscle cells
MOLECULAR AND CELLULAR BIOCHEMISTRY
Phospholipase C is involved in kinetochore function in Saccharomyces cerevisiae
MOLECULAR AND CELLULAR BIOLOGY
Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin
BIOCHEMICAL JOURNAL
Bcl-2-independent induction of apoptosis by neuropeptide receptor antagonist in human small cell lung carcinoma cells
ANTICANCER RESEARCH
(Tyr(0),Bpa(4))bombesin is a GRP receptor agonist
PEPTIDES
Bombesin-like peptide and receptors in lung injury models: diverse gene expression, similar function
PEPTIDES
Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism
HYPERTENSION
The role of protein kinase C in the regulation of cell growth and in signalling to the cell nucleus
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Early steps in termination of the immortalization state in Burkitt lymphoma: induction of genes involved in signal transduction, transcription, and trafficking by the ganglioside IV(3)NeuAc-nLcOse(4)Cer
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Adrenomedullin in cultured human retinal pigment epithelial cells
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
The metabolism of BW2258U89, a GRP receptor antagonist
NEUROPEPTIDES
Two amino acids in the sixth transmembrane segment of the mouse gastrin-releasing peptide receptor are important for receptor activation
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
A role for the small molecular weight GTPases, Rho and Cdc42, in muscarinic receptor signaling to focal adhesion kinase
JOURNAL OF NEUROCHEMISTRY
Synthesis and biological evaluation of bombesin constrained analogues
JOURNAL OF MEDICINAL CHEMISTRY
Simultaneous separation of lysophospholipids from the total lipid fractionof crude biological samples using two-dimensional thin-layer chromatography
JOURNAL OF LIPID RESEARCH