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KGF alters gene expression in human airway epithelia: potential regulationof the inflammatory response
PHYSIOLOGICAL GENOMICS
Differential properties of two putative nuclear localization sequences found in the carboxyl-terminus of human IFN-gamma
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Human primary CD4(+) T cells activated in the presence of IFN-alpha 2b express functional indoleamine 2,3-dioxygenase
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Identification of a gamma-interferon-responsive element in the promoter ofthe human macrophage scavenger receptor A gene
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
STAT1 is required for iNOS activation, but not IL-6 production in murine fibroblasts
CYTOKINE
The role of STAT1 in activation of IL-3-and IL-5-induced eosinophils by interferon gamma
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway
ONCOGENE
STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2
DEVELOPMENT
Role of signal transducers and activators of transcription 1 and-3 in inducible regulation of the human angiotensinogen gene by interleukin-6
MOLECULAR ENDOCRINOLOGY
Genomic organization of the gene for mouse PIAS gamma and analysis of its promoter
GENE
Sp1 is required for prolactin activation of the interferon regulatory factor-1 gene
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression
MOLECULAR AND CELLULAR ENDOCRINOLOGY
STAT1 from the cell membrane to the DNA
EMBO JOURNAL
Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
EMBO JOURNAL
Cloning and developmental expression of Xenopus Stat1
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
Herpes simplex virus type 1 suppresses the interferon signaling pathway byinhibiting phosphorylation of STATs and janus kinases during an early infection stage
VIROLOGY
Interferon alpha induction of Stat1 and Stat2 and their prognostic significance in carcinoid tumors
ONCOLOGY
Identification of two residues in MCM5 critical for the assembly of minichromosome maintenance complexes and signal transducer and activator of transcription-mediated transcription activation in response to IFN-gamma
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Cathepsins are upregulated by IFN-gamma/STAT1 in human muscle culture: A possible active factor in dermatomyositis
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Keratinocyte CDw60 expression is modulated by both a Th-1 type cytokine IFN-gamma and Th-2 cytokines IL-4 and IL-13: Relevance to psoriasis
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Transcriptional suppression of matrix metalloproteinase-9 gene expression by IFN-gamma and IFN-beta: Critical role of STAT-1 alpha
JOURNAL OF IMMUNOLOGY
The Smad3 protein is involved in TGF-beta inhibition of class II transactivator and class II MHC expression
JOURNAL OF IMMUNOLOGY
The receptor interaction region of Tyk2 contains a motif required for its nuclear localization
JOURNAL OF BIOLOGICAL CHEMISTRY
Suppressor of cytokine signaling-1 attenuates the duration of interferon gamma signal transduction in vitro and in vivo
JOURNAL OF BIOLOGICAL CHEMISTRY
Activation of the JAK/STAT pathway by ceramide in cultured human fibroblasts
FEBS LETTERS
IFN alpha sensitizes ME-180 human cervical cancer cells to TNF alpha-induced apoptosis by inhibiting cytoprotective NF-kappa-B activation
FEBS LETTERS
Prolactin activation of IRF-1 transcription involves changes in histone acetylation
FEBS LETTERS
p53-Independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma
EXPERIMENTAL CELL RESEARCH
Interferon-alpha drives T cell-mediated immunopathology in the intestine
EUROPEAN JOURNAL OF IMMUNOLOGY
Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1 alpha
EUROPEAN JOURNAL OF IMMUNOLOGY
Interferon-tau (IFN tau) regulation of IFN-stimulated gene expression in cell lines lacking specific IFN-signaling components
ENDOCRINOLOGY
PECAM-1 is a modulator of STAT family member phosphorylation and localization: Lessons from a transgenic mouse
DEVELOPMENTAL BIOLOGY
p53 independent G(1) arrest induced by DL-alpha-difluoromethylomithine
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Geranylgeranylacetone induces antiviral gene expression in human hepatoma cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
The direct effect of IL-12 on tumor cells: IL-12 acts directly on tumor cells to activate NF-kappa B and enhance IFN-gamma-mediated STAT1 phosphorylation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Intracellular signalling and antiviral effects of interferons
DIGESTIVE AND LIVER DISEASE
Interleukin-6 signal transduction in human intestinal epithelial cells
SHOCK
The role of p21 in interferon gamma-mediated growth inhibition of human breast cancer cells
CELL GROWTH & DIFFERENTIATION
IFN-gamma and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation
INTERNATIONAL IMMUNOLOGY
Regulation of CD26/DPPIV gene expression by interferons and retinoic acid in tumor B cells
ONCOGENE
Cloning and analysis of a murine PIAS family member, PIAS gamma, in developing skin and neurons
JOURNAL OF MOLECULAR NEUROSCIENCE
Pine bark extract pycnogenol downregulates IFN-gamma-induced adhesion of Tcells to human keratinocytes by inhibiting inducible ICAM-1 expression
FREE RADICAL BIOLOGY AND MEDICINE
The impact of interferon gamma receptor expression on the mechanism of escape from host immune surveillance in hepatocellular carcinoma
HEPATOLOGY
How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene
EMBO JOURNAL
Down-regulation of interferon-gamma signaling by gene transfer of Stat1 mutant in mesangial cells
KIDNEY INTERNATIONAL
The human papillomavirus E7 protein is able to inhibit the antiviral and anti-growth functions of interferon-alpha
VIROLOGY
Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response
VIROLOGY
The JAK-STAT signaling pahway and its role in oncogenesis, immunomodulation and development
MEDICINA CLINICA
Evasion of host defenses by measles virus: Wild-type measles virus infection interferes with induction of alpha/beta interferon production
JOURNAL OF VIROLOGY
Chronopharmacology of antitumor effect induced by interferon-beta in tumor-bearing mice
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Synergistic induction of the Tap-1 gene by IFN-gamma and lipopolysaccharide in macrophages is regulated by STAT1
JOURNAL OF IMMUNOLOGY
Spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice
JOURNAL OF IMMUNOLOGY
Epiregulin, a novel member of the epidermal growth factor family, is an autocrine growth factor in normal human keratinocytes
JOURNAL OF BIOLOGICAL CHEMISTRY
Interferon-alpha induces Nmi-IFP35 heterodimeric complex formation that isaffected by the phosphorylation of IFP35
JOURNAL OF BIOLOGICAL CHEMISTRY
Detection of differentially expressed genes in breast cancer with cDNA-array hybridization
GEBURTSHILFE UND FRAUENHEILKUNDE
TNF alpha and IFN gamma potentiate IL-1 beta induced mitogen activated protein kinase activity in rat pancreatic islets of Langerhans
DIABETOLOGIA
The antagonism of interferon-gamma (IFN-gamma) by heparin: examination of the blockade of class II MHC antigen and heat shock protein-70 expression
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells
CANCER RESEARCH
Interferon-alpha 2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism
BRITISH JOURNAL OF CANCER
Inhibition of interleukin-6 signaling and Stat3 activation by a new class of bioactive cyclopentenone derivatives
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
The Epstein-Barr virus nuclear antigen 2 (EBNA2), a protein required for Blymphocyte immortalization, induces the synthesis of type I interferon in Burkitt's lymphoma cell lines
BIOLOGICAL CHEMISTRY
Ly-6A/E induction by interleukin-6 and interleukin-9 in T cells
EUROPEAN CYTOKINE NETWORK
Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line
DEVELOPMENTAL DYNAMICS
Signal transduction through interferon-gamma receptor on human eosinophils
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
The decline of human gastric cancer cells' proliferation and responsiveness to EGF by down-regulation of c-erbB-2 expression
PROGRESS IN NATURAL SCIENCE
The induction and activation of STAT1 by all-trans-retinoic acid are mediated by RAR beta signaling pathways in breast cancer cells
ONCOGENE
Retinoic acid and interferon signaling cross talk in normal and RA-resistant APL cells
LEUKEMIA
Lineage-specific activation of STAT3 by interferon-gamma in human neutrophils
JOURNAL OF LEUKOCYTE BIOLOGY
Salicylate-enhanced activation of transcription factors induced by interferon-gamma
BIOCHEMICAL JOURNAL
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
EMBO JOURNAL
A candidate interferon-gamma activated site (GAS element) in the HLA-G promoter does not bind nuclear proteins
HUMAN IMMUNOLOGY
Stat3 as an oncogene
CELL
Mechanism of interferon action: Functional characterization of positive and negative regulatory domains that modulate transcriptional activation of the human RNA-dependent protein kinase Pkr promoter
VIROLOGY
Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Distinctive gene expression patterns in human mammary epithelial cells andbreast cancers
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway
JOURNAL OF VIROLOGY
Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma
JOURNAL OF IMMUNOLOGY
Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion
JOURNAL OF EXPERIMENTAL MEDICINE
Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes
JOURNAL OF EXPERIMENTAL MEDICINE
Knockout of the Sendai virus C gene eliminates the viral ability to prevent the interferon-alpha/beta-mediated responses
FEBS LETTERS
Transcriptional induction of the p69 isoform of 2 ',5 '-oligoadenylate synthetase by interferon-beta and interferon-gamma involves three regulatory elements and interferon-stimulated gene factor 3
EXPERIMENTAL CELL RESEARCH
Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens
DEVELOPMENTAL BIOLOGY
Role of JAK2 signal transductional pathway in activation and survival of human peripheral eosinophils by interferon-gamma (IFN-gamma)
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Sodium butyrate blocks interferon-gamma (IFN-gamma)-induced biosynthesis of MHC class III gene products (complement C4 and factor B) in human fetal intestinal epithelial cells
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Interferon signaling pathways
BULLETIN DU CANCER
Cytotoxic response of ovarian cancer cell lines to IFN-gamma is associatedwith sustained induction of IRF-1 and p21 mRNA
BRITISH JOURNAL OF CANCER
ANALYSIS OF THE ANTAGONIST EFFECT OF IFN-ALPHA ON IFN-GAMMA-INDUCED INTERFERON CONSENSUS SEQUENCE BINDING-PROTEIN MESSENGER-RNA IN MURINE MACROPHAGES
Journal of inflammation
UV-LIGHT AFFECTS CELL-MEMBRANE AND CYTOPLASMIC TARGETS
Journal of photochemistry and photobiology.B, Biology
INTERFERON-GAMMA AND INTERLEUKIN-6 INHIBIT PROLIFERATION IN HUMAN-MELANOMA CELLS BY DIFFERENT SIGNALING PATHWAYS
Melanoma research
FGF SIGNALING ACTIVATES STAT1 AND P21 AND INHIBITS THE ESTROGEN RESPONSE AND PROLIFERATION OF MCF-7 CELLS
Oncogene
THE DROSOPHILA ZYGOTIC LETHAL GENE SHUTTLE CRAFT IS REQUIRED MATERNALLY FOR PROPER EMBRYONIC-DEVELOPMENT
Development, genes and evolution
MOLECULAR MECHANISMS OF INFLAMMATION - IN TERLEUKIN-6-TYPE CYTOKINE SIGNALING THROUGH THE JAK STAT PATHWAY/
Nieren- und Hochdruckkrankheiten
Ser727-dependent recruitment of MCM5 by Stat1 alpha in IFN-gamma-induced transcriptional activation
EMBO JOURNAL
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
EMBO JOURNAL
JAK STAT-DEFICIENT CELL-LINES
Brazilian journal of medical and biological research
HOW CELLS RESPOND TO INTERFERONS
Annual review of biochemistry
INHIBITION OF STAT1-MEDIATED GENE ACTIVATION BY PIAS1
Proceedings of the National Academy of Sciences of the United Statesof America
TRANSCRIPTION FACTOR P91 STAT1 IS CONSTITUTIVELY PHOSPHORYLATED AT TYROSINE AND BOUND TO MAP KINASE IN THE RAT EMBRYO FIBROBLASTS TRANSFORMED BY E1A+HA-RAS ONCOGENES/
Molecular biology
MECHANISM OF INTERFERON ACTION - IDENTIFICATION OF ESSENTIAL POSITIONS WITHIN THE NOVEL 15-BASE-PAIR KCS ELEMENT REQUIRED FOR TRANSCRIPTIONAL ACTIVATION OF THE RNA-DEPENDENT PROTEIN-KINASE PKR GENE
Journal of virology (Print)