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1. Begemann, M; Fuller, GN; Holland, EC
   Genetic modeling of glioma formation in mice
   BRAIN PATHOLOGY
   
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2. Kim, HJ; Lee, HH; Yoo, HD; Lee, JH; Hong, ST
   Development of a solid-phase binding assay and identification of nonpeptide ligands for the FynB Src homology 2 domain
   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
   
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3. Lowry, WE; Ma, YC; Cvejic, S; Huang, XY
   Direct stimulation of Bruton's tyrosine kinase by G protein alpha subunits
   G PROTEIN PATHWAYS: PT C, EFFECTOR MECHANISMS
   
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4. Rajapurohitam, V; Chalhoub, N; Benachenhou, N; Neff, L; Baron, R; Vacher, J
   The mouse osteopetrotic grey-lethal mutation induces a defect in osteoclast maturation/function
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5. Violette, SM; Guan, W; Bartlett, C; Smith, JA; Bardelay, C; Antoine, E; Rickles, RJ; Mandine, E; Van Schravendijk, MR; Adams, SE; Lynch, BA; Shakespeare, WC; Yang, M; Jacobsen, VA; Takeuchi, CS; Macek, KJ; Bohacek, RS; Dalgarno, DC; Weigele, M; Lesuisse, D; Sawyer, TK; Baron, R
   Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption
   BONE
   
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6. Gerthoffer, WT; Gunst, SJ
   Signal Transduction in smooth muscle - Invited review: Focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle
   JOURNAL OF APPLIED PHYSIOLOGY
   
   W.T. Gerthoffer e S.J. Gunst, "Signal Transduction in smooth muscle - Invited review: Focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle", J APP PHYSL, 91(2), 2001, pp. 963-972
7. He, H; Hirokawa, Y; Manser, E; Lim, L; Levitzki, A; Maruta, H
   Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation
   CANCER JOURNAL
   
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8. Brunton, VG; Fincham, VJ; McLean, GW; Winder, SJ; Paraskeva, C; Marshall, JR; Frame, MC
   The protrusive phase and full development of integrin-dependent adhesions in colon epithelial cells require FAK- and ERK-mediated actin spike formation: Deregulation in cancer cells
   NEOPLASIA
   
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9. Macoska, JA; Xu, JL; Ziemnicka, D; Schwab, TS; Rubin, MA; Kotula, L
   Loss of expression of human spectrin src homology domain binding protein 1is associated with 10p loss in human prostatic adenocarcinoma
   NEOPLASIA
   
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10. Viola, A
    The amplification of TCR signaling by dynamic membrane microdomains
    TRENDS IN IMMUNOLOGY
    
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11. Martin, GS
    The hunting of the Src
    NATURE REVIEWS MOLECULAR CELL BIOLOGY
    
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12. Geiger, B; Bershadsky, A; Pankov, R; Yamada, KM
    Transmembrane extracellular matrix-cytoskeleton crosstalk
    NATURE REVIEWS MOLECULAR CELL BIOLOGY
    
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13. Pierce, KL; Lefkowitz, RJ
    Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors
    NATURE REVIEWS NEUROSCIENCE
    
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14. Gravallese, EM; Galson, DL; Goldring, SR; Auron, PE
    The role of TNF-receptor family members and other TRAF-dependent receptorsin bone resorption
    ARTHRITIS RESEARCH
    
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15. Chiariello, M; Marinissen, MJ; Gutkind, JS
    Regulation of c-myc expression by PDGF through Rho GTPases
    NATURE CELL BIOLOGY
    
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16. Chen, RY; Kim, O; Li, M; Xiong, XS; Guan, JL; Kung, HJ; Chen, HG; Shimizu, Y; Qiu, Y
    Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain
    NATURE CELL BIOLOGY
    
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17. Brouns, MR; Matheson, SF; Settleman, J
    p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
    NATURE CELL BIOLOGY
    
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18. Habelhah, H; Shah, K; Huang, L; Ostareck-Lederer, A; Burlingame, AL; Shokat, KM; Hentze, MW; Ronai, Z
    ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation
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19. Ruijtenbeek, R; Kruijtzer, JAW; van de Wiel, W; Fischer, MJE; Fluck, M; Redegeld, FAM; Liskamp, RMJ; Nijkamp, FP
    Peptoid-peptide hybrids that bind Syk SH2 domains involved in signal transduction
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20. Zou, KY; Miller, WT; Givens, RS; Bayley, H
    Caged thiophosphotyrosine peptides
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21. Vyas, KA; Patel, HV; Vyas, AA; Schnaar, RL
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22. Carver, FM; Shibley, IA; Pennington, JS; Pennington, SN
    Differential expression of glucose transporters during chick embryogenesis
    CELLULAR AND MOLECULAR LIFE SCIENCES
    
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23. Kay, BK; Hamilton, PT
    Identification of enzyme inhibitors from phage-displayed combinatorial peptide libraries
    COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
    
    B.K. Kay e P.T. Hamilton, "Identification of enzyme inhibitors from phage-displayed combinatorial peptide libraries", COMB CHEM H, 4(7), 2001, pp. 535-543
24. Budde, RJA; Ramdas, L; Sun, GQ
    Cloning, expression, purification and characterization of the alternate splice Src variants for drug discovery
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    
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25. Shakespeare, WC
    SH2 domain inhibition: a problem solved?
    CURRENT OPINION IN CHEMICAL BIOLOGY
    
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26. Afanasieva, TA; Pekarik, V; D'Angelo, MG; Klein, MA; Voigtlander, T; Stocking, C; Aguzzi, A
    Insertional mutagenesis of preneoplastic astrocytes by Moloney murine leukemia virus
    JOURNAL OF NEUROVIROLOGY
    
    T.A. Afanasieva et al., "Insertional mutagenesis of preneoplastic astrocytes by Moloney murine leukemia virus", J NEUROVIRO, 7(2), 2001, pp. 169-181
27. Rice, VM; Chaudhery, AR; Oluola, O; Limback, SD; Roby, KF; Terranova, PF
    Herbimycin, a tyrosine kinase inhibitor with Src selectivity, reduces progesterone and estradiol secretion by human granulosa cells
    ENDOCRINE
    
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28. Sawyer, T; Boyce, B; Dalgarno, D; Iuliucci, J
    Src inhibitors: genomics to therapeutics
    EXPERT OPINION ON INVESTIGATIONAL DRUGS
    
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29. Conti, L; Sipione, S; Magrassi, L; Bonfanti, L; Rigamonti, D; Pettirossi, V; Peschanski, M; Haddad, B; Pelicci, P; Milanesi, G; Pelicci, G; Cattaneo, E
    Shc signaling in differentiating neural progenitor cells
    NATURE NEUROSCIENCE
    
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30. Zhou, YJ; Chen, M; Cusack, NA; Kimmel, LH; Magnuson, KS; Boyd, JG; Lin, W; Roberts, JL; Lengi, A; Buckley, RH; Geahlen, RL; Candotti, F; Gadina, M; Changelian, PS; O'Shea, JJ
    Unexpected effects of FERM domain mutations on catalytic activity of Jak3:Structural implication for Janus kinases
    MOLECULAR CELL
    
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31. Thien, CBF; Walker, F; Langdon, WY
    RING finger mutations that abolish C-Cbl-directed polyubiquitination and downregulation of the EGF receptor ave insufficient for cell transformation
    MOLECULAR CELL
    
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32. Gottlieb, KA; Villarreal, LP
    Natural biology of polyomavirus middle T antigen
    MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
    
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33. Grunebaum, E; Roifman, CM
    Signal-transduction defects in T cells
    CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
    
    E. Grunebaum e C.M. Roifman, "Signal-transduction defects in T cells", CL R ALL IM, 20(1), 2001, pp. 27-42
34. Ochs, HD
    The Wiskott-Aldrich syndrome
    CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
    
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35. Harder, KW; Parsons, LM; Armes, J; Evans, N; Kountouri, N; Clark, R; Quilici, C; Grail, D; Hodgson, GS; Dunn, AR; Hibbs, ML
    Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role of Lyn in the myeloid lineage
    IMMUNITY
    
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36. Langille, BL
    Morphologic responses of endothelium to shear stress: Reorganization of the adherens junction
    MICROCIRCULATION
    
    B.L. Langille, "Morphologic responses of endothelium to shear stress: Reorganization of the adherens junction", MICROCIRCUL, 8(3), 2001, pp. 195-206
37. Choudhry, MA; Fazal, N; Namak, SY; Haque, F; Ravindranath, T; Sayeed, MM
    PGE(2) suppresses intestinal T cell function in thermal injury: A cause ofenhanced bacterial translocation
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38. Hiroaki, H; Ago, T; Ito, T; Sumimoto, H; Kohda, D
    Solution structure of the PX domain, a target of the SH3 domain
    NATURE STRUCTURAL BIOLOGY
    
    H. Hiroaki et al., "Solution structure of the PX domain, a target of the SH3 domain", NAT ST BIOL, 8(6), 2001, pp. 526-530
39. Ghose, R; Shekhtman, A; Goger, MJ; Ji, H; Cowburn, D
    A novel, specific interaction involving the Csk SH3 domain and its naturalligand
    NATURE STRUCTURAL BIOLOGY
    
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40. Islam, S; Kermode, T; Sultana, D; Moskowitz, RW; Mukhtar, H; Malemud, CJ; Goldberg, VM; Haqqi, TM
    Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes
    OSTEOARTHRITIS AND CARTILAGE
    
    S. Islam et al., "Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes", OSTEO CART, 9(8), 2001, pp. 684-693
41. Frangos, SG; Knox, R; Yano, Y; Chen, E; Di Luozzo, G; Chen, AH; Sumpio, BE
    The integrin-mediated cyclic strain-induced signaling pathway in vascular endothelial cells
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42. Arthur, WT; Burridge, K
    RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
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43. Vara, JAF; Caceres, AD; Silva, A; Martin-Perez, J
    Src family kinases are required for prolactin induction of cell proliferation
    MOLECULAR BIOLOGY OF THE CELL
    
    J.A.F. Vara et al., "Src family kinases are required for prolactin induction of cell proliferation", MOL BIOL CE, 12(7), 2001, pp. 2171-2183
44. Aznar, S; Valeron, PF; del Rincon, SV; Perez, LF; Perona, R; Lacal, JC
    Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation
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45. Weinstein, DC; Hemmati-Brivanlou, A
    Src family kinase function during early Xenopus development
    DEVELOPMENTAL DYNAMICS
    
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46. Mirny, L; Shakhnovich, E
    Protein folding theory: From lattice to all-atom models
    ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE
    
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47. Kohn, KW
    Molecular interaction maps as information organizers and simulation guides
    CHAOS
    
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48. Hawkins, J; Marcy, A
    Characterization of Itk tyrosine kinase: Contribution of noncatalytic domains to enzymatic activity
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49. Sun, GQ; Budde, RJA
    Affinity purification of Csk protein tyrosine kinase based on its catalytic requirement for divalent metal cations
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50. Kay, BK; Kasanov, J; Yamabhai, M
    Screening phage-displayed combinatorial peptide libraries
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51. Scholz, GM; Hartson, SD; Cartledge, K; Volk, L; Matts, RL; Dunn, AR
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52. Boney, CM; Sekimoto, H; Gruppuso, PA; Frackelton, AR
    Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells
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53. Zhong, MH; Lu, ZM; Abbas, T; Hornia, A; Chatakondu, K; Barile, N; Kaplan, P; Foster, DA
    Novel tumor-promoting property of tamoxifen
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54. Kazansky, AV; Rosen, JM
    Signal transducers and activators of transcription 5B potentiates v-Src-mediated transformation of NIH-3T3 cells
    CELL GROWTH & DIFFERENTIATION
    
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55. Reilly, KM; Jacks, T
    Genetically engineered mouse models of astrocytoma: GEMs in the rough?
    SEMINARS IN CANCER BIOLOGY
    
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56. Holowka, D; Baird, B
    Fc epsilon RI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells
    SEMINARS IN IMMUNOLOGY
    
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57. Miceli, MC; Moran, M; Chung, CD; Patel, VP; Low, T; Zinnanti, W
    Co-stimulation and counter-stimulation: lipid raft clustering controls TCRsignaling and functional outcomes
    SEMINARS IN IMMUNOLOGY
    
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58. Lee, JH; Kaminski, N; Dolganov, G; Grunig, G; Koth, L; Solomon, C; Erle, DJ; Sheppard, D
    Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    
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59. Vidal, M; Gigoux, V; Garbay, C
    SH2 and SH3 domains as targets for anti-proliferative agents
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
    
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60. Belton, RJ; Adams, NL; Foltz, KR
    Isolation and characterization of sea urchin egg lipid rafts and their possible function during fertilization
    MOLECULAR REPRODUCTION AND DEVELOPMENT
    
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61. Tiruppathi, C; Naqvi, T; Sandoval, R; Mehta, D; Malik, AB
    Synergistic effects of tumor necrosis factor-alpha and thrombin in increasing endothelial permeability
    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    
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62. Berclaz, G; Altermatt, HJ; Rohrbach, V; Siragusa, A; Dreher, E; Smith, PD
    EGFR dependent expression of STAT3 (but not STAT1) in breast cancer
    INTERNATIONAL JOURNAL OF ONCOLOGY
    
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63. Bishop, AC; Buzko, O; Shokat, KM
    Magic bullets for protein kinases
    TRENDS IN CELL BIOLOGY
    
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64. Pawson, T; Gish, GD; Nash, P
    SH2 domains, interaction modules and cellular wiring
    TRENDS IN CELL BIOLOGY
    
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65. Kishan, KVR; Newcomer, ME; Rhodes, TH; Guilliot, SD
    Effect of pH and salt bridges on structural assembly: Molecular structuresof the monomer and intertwined dimer of the Eps8 SH3 domain
    PROTEIN SCIENCE
    
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66. Ojennus, DD; Fleissner, MR; Wuttke, DS
    Reconstitution of a native-like SH2 domain from disordered peptide fragments examined by multidimensional heteronuclear NMR
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67. Weaver, AM; Karginov, AV; Kinley, AW; Weed, SA; Li, Y; Parsons, JT; Cooper, JA
    Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
    CURRENT BIOLOGY
    
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68. Timpson, P; Jones, GE; Frame, MC; Brunton, VG
    Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity
    CURRENT BIOLOGY
    
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69. Echarri, A; Pendergast, AM
    Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway
    CURRENT BIOLOGY
    
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70. Giepmans, BNG; Verlaan, I; Hengeveld, T; Janssen, H; Calafat, J; Falk, MM; Moolenaar, WH
    Gap junction protein connexin-43 interacts directly with microtubules
    CURRENT BIOLOGY
    
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71. Widler, L; Green, J; Missbach, M; Susa, M; Altmann, E
    7-alkyl- and 7-cycloalkyl-5-aryl-pyrrolo[2,3-d]pyrimidines - potent inhibitors of the tyrosine kinase c-Src
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
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72. Kawahata, N; Yang, MG; Luke, GP; Shakespeare, WC; Sundaramoorthi, R; Wang, YH; Johnson, D; Merry, T; Violette, S; Guan, W; Bartlett, C; Smith, J; Hatada, M; Lu, XD; Dalgarno, DC; Eyermann, CJ; Bohacek, RS; Sawyer, TK
    A novel phosphotyrosine mimetic 4 '-carboxymethyloxy-3 '-phosphonophenylalanine (Cpp): Exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain
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73. Papageorgiou, C; Camenisch, G; Borer, X
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74. Tremblay, A; Vincent, G
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75. Perez, M; Migliaccio, S; Taranta, A; Festuccia, C; Orru, L; Brama, M; Bologna, M; Faraggiana, T; Baron, R; Teti, A
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76. Gunasekaran, K; Eyles, SJ; Hagler, AT; Gierasch, LM
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77. Kouro, T; Nagata, K; Takaki, S; Nisitani, S; Hirano, R; Wahl, MI; Witte, ON; Karasuyama, H; Takatsu, K
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78. Mandine, E; Gofflo, D; Jean-Baptiste, V; Sarubbi, E; Touyer, G; Deprez, P; Lesuisse, D
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79. Lewitzky, M; Kardinal, C; Gehring, NH; Schmidt, EK; Konkol, B; Eulitz, M; Birchmeier, W; Schaeper, U; Feller, SM
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80. Acquaviva, C; Salvat, C; Brockly, F; Bossis, G; Ferrara, P; Piechaczyk, M; Jariel-Encontre, I
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81. Benaud, CM; Dickson, RB
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82. Dorey, K; Engen, JR; Kretzschmar, J; Wilm, M; Neubauer, G; Schindler, T; Superti-Furga, G
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83. Baisden, JM; Gatesman, AS; Cherezova, L; Jiang, BH; Flynn, DC
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84. Okutani, Y; Kitanaka, A; Tanaka, T; Kamano, H; Ohnishi, H; Kubota, Y; Ishida, T; Takahara, J
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85. Wonerow, P; Watson, SP
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86. O'Bryan, JP; Mohney, RP; Oldham, CE
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87. Feller, SM
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88. Li, W; Fan, JH; Woodley, DT
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89. Baisden, JM; Qian, Y; Zot, HM; Flynn, DC
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90. Bouton, AH; Riggins, RB; Bruce-Staskal, PJ
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91. Riley, D; Carragher, N; Frame, MC; Wyke, JA
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92. Yokoyama, N; Miller, WT
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93. Schuringa, JJ; Wojtachnio, K; Hagens, W; Vellenga, E; Buys, CHCM; Hofstra, R; Kruijer, W
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94. Song, Y; Cohler, AN; Weinstein, DC
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95. Luciano, F; Ricci, JE; Auberger, P
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96. Miyoshi-Akiyama, T; Aleman, LM; Smith, JM; Adler, CE; Mayer, BJ
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97. Crostella, L; Lidder, S; Williams, R; Skouteris, GG
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98. Nakamura, K; Yano, H; Schaefer, E; Sabe, HA
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99. Garcia, R; Bowman, TL; Niu, GL; Yu, H; Minton, S; Muro-Cacho, CA; Cox, CE; Falcone, R; Fairclough, R; Parsons, S; Laudano, A; Gazit, A; Levitzki, A; Kraker, A; Jove, R
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100. Gagliardi, M; Maynard, S; Bojovic, B; Bedard, PA
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