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The p53 tumor suppressor: Critical regulator of life & death in cancer
APOPTOSIS
Use of dendritic cells to immunize against cancers overexpressing p53
CLINICAL CANCER RESEARCH
Cellular transformation by SV40 large T antigen: interaction with host proteins
SEMINARS IN CANCER BIOLOGY
Prospects for an SV40 vaccine
SEMINARS IN CANCER BIOLOGY
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity
ONCOGENE
Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis
ONCOGENE
p73 is a growth-regulated protein in vascular smooth muscle cells and is present at high levels in human atherosclerotic plaque
CELLULAR SIGNALLING
p53-mediated apoptosis and genomic instability diseases
ACTA ONCOLOGICA
Simian virus 40 large-T-antigen-specific rejection of mKSA tumor cells in BALB/c mice is critically dependent on both strictly tumor-associated, tumor-specific CD8(+) cytotoxic T lymphocytes and CD4(+) T helper cells
JOURNAL OF VIROLOGY
Inhibition of p53 tumor suppressor by viral interferon regulatory factor
JOURNAL OF VIROLOGY
Feedback regulation between orphan nuclear receptor TR2 and human papilloma virus type 16
JOURNAL OF BIOLOGICAL CHEMISTRY
From p63 to p53 across p73
FEBS LETTERS
Transient expression of wild-type or biologically inactive telomerase allows the formation of artificial telomeres in mortal human cells
EXPERIMENTAL CELL RESEARCH
Prostate carcinomas developing in transgenic rats with SV40 T antigen expression under probasin promoter control are strictly androgen dependent
CANCER RESEARCH
c-jun cooperates with SV40 T-antigen to sustain MMP-2 expression in immortalized cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Hepatic expression of SV40 small-t antigen blocks the in vivo CD95-Mediated apoptosis
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Androgens and growth factors in prostate cancer: a transgenic perspective
PROSTATE CANCER AND PROSTATIC DISEASES
Characterization of cytochrome P450-dependent and glutathione transferase activities in SV40-immortalized uroepithelial cell lines: Possible role in transformation and tumor formation
TOXICOLOGY METHODS
Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers
GENES CHROMOSOMES & CANCER
Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015
SEMINARS IN CANCER BIOLOGY
Relationship between p53 gene mutation and protein expression: Clinical significance in transitional cell carcinoma of the bladder
INTERNATIONAL JOURNAL OF ONCOLOGY
Reversal of an antiestrogen-mediated cell cycle arrest of MCF-7 cells by viral tumor antigens requires the retinoblastoma protein-binding domain
ONCOGENE
p53-independent association between SV40 large T antigen and the major cytosolic heat shock protein, HSP90
ONCOGENE
Prognostic and predictive significance of p53 mutation in aggressive B-cell lymphoma
INTERNATIONAL JOURNAL OF HEMATOLOGY
Reduced global genomic repair of ultraviolet light-induced cyclobutane pyrimidine dimers in simian virus 40-transformed human cells
MOLECULAR CARCINOGENESIS
Controlling gene expression in mice with tetracycline: Application in pigment cell research
PIGMENT CELL RESEARCH
p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect
FASEB JOURNAL
Effects of oxidation agents and metal ions on binding of p53 to supercoiled DNA
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
p63 and p73: Old members of a new family
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF
MOLECULAR AND CELLULAR BIOLOGY
Species-specific elements in the large T-antigen J domain are required forcellular transformation and DNA replication by simian virus 40
MOLECULAR AND CELLULAR BIOLOGY
Liver-directed gene therapy: promises, problems and prospects at the turn of the century
JOURNAL OF HEPATOLOGY
Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease
CARCINOGENESIS
Virology in the next millennium
CELL
J domain-independent regulation of the Rb family by polyomavirus large T antigen
JOURNAL OF VIROLOGY
Physical and functional interaction between p53 mutants and different isoforms of p73
JOURNAL OF BIOLOGICAL CHEMISTRY
New insights into p53 regulation and gene therapy for cancer
BIOCHEMICAL PHARMACOLOGY
Introduction: p53 - the first twenty years
CELLULAR AND MOLECULAR LIFE SCIENCES
Regulation of p53 protein function through alterations in protein-folding pathways
CELLULAR AND MOLECULAR LIFE SCIENCES
Cancer therapy based on p53
CANCER JOURNAL FROM SCIENTIFIC AMERICAN
Nuclear factor kappa B cooperates with c-Myc in promoting murine hepatocyte survival in a manner independent of p53 tumor suppressor function
CELL GROWTH & DIFFERENTIATION
Clinical significance of p53 in non-small cell lung cancer (Review)
ONCOLOGY REPORTS
Overexpression of p53 protein associated with proliferative activity and histological degree of malignancy in solar keratosis
DERMATOLOGY
mdm2: a bridge over the two tumour suppressors, p53 and Rb
ONCOGENE
Heterotopic endochondrial ossification with mixed tumor formation in C3(1)/Tag transgenic mice is associated with elevated TGF-beta1 and BMP-2 expression
ONCOGENE
Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha
ONCOGENE
The role of the p53 tumour suppressor gene in human breast cancer
CLINICAL ONCOLOGY
Gene delivery to the liver using simian virus 40-derived vectors
SEMINARS IN LIVER DISEASE
Chromosomal imbalances and DNA amplifications in SV40 large T antigen-induced primitive neuroectodermal tumor cell lines of the rat
CARCINOGENESIS
A double staining method for histone H3 mRNA and p53 protein in oral tumors using in situ hybridization and immunohistochemistry
ACTA HISTOCHEMICA ET CYTOCHEMICA
The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300
JOURNAL OF VIROLOGY
The P53 pathway
JOURNAL OF PATHOLOGY
Gene therapy using SV40-derived vectors: What does the future hold?
JOURNAL OF CELLULAR PHYSIOLOGY
Comparative analysis of p73 and p53 regulation and effector functions
JOURNAL OF CELL BIOLOGY
Regulation of the p53 protein by the MDM2 oncoprotein - Thirty-eighth G.H.A. Clowes Memorial Award lecture
CANCER RESEARCH
The influence of SV40 immortalization of human fibroblasts on p53-dependent radiation responses
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
The emerging p53 gene family
JOURNAL OF THE NATIONAL CANCER INSTITUTE
Induction of tumor antigen-specific immunity in vivo by a novel vaccinia vector encoding safety-modified simian virus 40 T antigen
JOURNAL OF THE NATIONAL CANCER INSTITUTE
CURRENT ISSUES IN MUTAGENESIS AND CARCINOGENESIS, NO. 85 - TRANSGENICRODENT MUTATION CANCER BIOASSAYS - CELL-CYCLE CONTROL, CELL-PROLIFERATION AND APOPTOSIS AS MODIFIERS OF OUTCOME
Mutation research. Fundamental and molecular mechanisms of mutagenesis
DETECTION OF P53 GENE-MUTATIONS IN ORAL SQUAMOUS-CELL CARCINOMAS OF ABLACK-AFRICAN POPULATION-SAMPLE
Human mutation
DETECTION OF P53 GENE-MUTATIONS IN ORAL SQUAMOUS-CELL CARCINOMAS OF ABLACK-AFRICAN POPULATION-SAMPLE
Human mutation
Clinical implications of p53: effect on prognosis, tumor progression and chemotherapy response
SEMINARS IN CANCER BIOLOGY
PROGNOSTIC-SIGNIFICANCE OF P53 GENE-MUTATIONS IN SQUAMOUS-CELL CARCINOMA OF THE LUNG
Oncology Reports
Paediatric update - Gliomas
EUROPEAN JOURNAL OF CANCER
DEFINING THE MINIMAL REQUIREMENTS FOR PAPILLOMA VIRAL E6-MEDIATED INHIBITION OF HUMAN P53 ACTIVITY IN FISSION YEAST
Oncogene
FEW POINT MUTATIONS IN ELONGATION FACTOR-1-GAMMA GENE IN GASTROINTESTINAL CARCINOMA
Molecular carcinogenesis
LOW CATALASE ACTIVITY IN XERODERMA-PIGMENTOSUM FIBROBLASTS AND SV40-TRANSFORMED HUMAN CELL-LINES IS DIRECTLY RELATED TO DECREASED INTRACELLULAR LEVELS OF THE COFACTOR, NADPH
Free radical biology & medicine
E1A SIGNALING TO P53 INVOLVES THE P19(ARF) TUMOR-SUPPRESSOR
Genes & development
GENE-THERAPY FOR COLON-CANCER
Hematology/oncology clinics of North America
A TRUNCATED SV40 LARGE T-ANTIGEN LACKING THE P53 BINDING DOMAIN OVERCOMES P53-INDUCED GROWTH ARREST AND IMMORTALIZES PRIMARY MESENCEPHALIC CELLS
Cell and tissue research
N18-RE-105 CELLS - DIFFERENTIATION AND ACTIVATION OF P53 IN RESPONSE TO GLUTAMATE AND ADRIAMYCIN IS BLOCKED BY SV40 LARGE T-ANTIGEN TSA58
Cell and tissue research
VIRAL ONCOPROTEINS DISCRIMINATE BETWEEN P53 AND THE P53 HOMOLOG P73
Molecular and cellular biology (Print)
A reassessment of the telomere hypothesis of senescence
BIOESSAYS
THE HUMAN ONCOPROTEIN MDM2 ARRESTS THE CELL-CYCLE - ELIMINATION OF ITS CELL-CYCLE-INHIBITORY FUNCTION INDUCES TUMORIGENESIS
EMBO journal
DEXAMETHASONE-INDUCED RADIORESISTANCE OCCURRING INDEPENDENT OF HUMAN PAPILLOMA-VIRUS GENE-EXPRESSION IN CERVICAL-CARCINOMA CELLS
Strahlentherapie und Onkologie
ROLE OF A SUBDOMINANT H-2K(D)-RESTRICTED SV40 TUMOR-ANTIGEN CYTOTOXICT-LYMPHOCYTE EPITOPE IN TUMOR REJECTION
Virology
Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ROLES OF THE TUMOR-SUPPRESSOR P53 AND THE CYCLIN-DEPENDENT KINASE INHIBITOR P21(WAF1 CTP1) IN RECEPTOR-MEDIATED APOPTOSIS OF WEHI-231 B-LYMPHOMA-CELLS/
The Journal of experimental medicine
Interaction of the single-stranded DNA-binding protein Pur alpha with the human polyomavirus JC virus early protein T-antigen
JOURNAL OF BIOLOGICAL CHEMISTRY
IMMORTALIZATION OF RAT EMBRYO FIBROBLASTS BY A 3'-UNTRANSLATED REGION
Experimental cell research
THE P53 TUMOR-SUPPRESSOR GENE
British Journal of Surgery
DNA tumor viruses: probes for the discovery of tumour suppressor genes
EUROCANCER 98
DIFFERENTIATION IS INHIBITED AND A SENESCENCE PATHWAY IS ACTIVATED WHEN SIMIAN-VIRUS-40 TSA 58-TRANSFORMED HUMAN RETINOBLASTS ARE GROWN AT THE RESTRICTIVE TEMPERATURE
Cell growth & differentiation
INTERACTION OF P53 WITH PROTEIN-KINASE CK2 DURING SV40 INDUCED ENTRANCE OF QUIESCENT CELLS INTO THE CELL-CYCLE
International journal of oncology
MDM2 - ARBITER OF P53S DESTRUCTION
Trends in biochemical sciences
GROWTH-PROPERTIES OF NEURAL CELL-LINES IMMORTALIZED WITH THE TSA58 ALLELE OF SV40 LARGE T-ANTIGEN
Cell transplantation
P53 ASSOCIATES WITH TRK TYROSINE KINASE
Oncogene
P53-MEDIATED ACCUMULATION OF HYPOPHOSPHORYLATED PRB AFTER THE G(1) RESTRICTION POINT FAILS TO HALT CELL-CYCLE PROGRESSION
Oncogene
LOSS OF FUNCTION AND P53 PROTEIN STABILIZATION
Oncogene
P53 PROTEIN STABILITY IN TUMOR-CELLS IS NOT DETERMINED BY MUTATION BUT IS DEPENDENT ON MDM2 BINDING
Oncogene
IDENTIFICATION OF P53 UNBOUND TO T-ANTIGEN IN HUMAN-CELLS TRANSFORMEDBY SIMIAN-VIRUS-40 T-ANTIGEN
Oncogene
POLYOMAVIRUS LARGE-T-ANTIGEN-DEPENDENT DNA AMPLIFICATION
Oncogene
PACT - CLONING AND CHARACTERIZATION OF A CELLULAR P53 BINDING-PROTEINTHAT INTERACTS WITH RB
Oncogene
2 FUNCTIONAL ASSAYS EMPLOYED TO DETECT AN UNUSUAL MUTATION IN THE OLIGOMERIZATION DOMAIN OF P53 IN A LI-FRAUMENI LIKE FAMILY
Oncogene
EXPRESSION OF PCNA AND P53 IN ESOPHAGEAL DYSPLASIA AND ESOPHAGEAL-CARCINOMA
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY
ISOLATION AND IDENTIFICATION OF THE HUMAN HOMOLOG OF A NEW P53-BINDING PROTEIN, MDMX
Genomics
HUMAN PAPILLOMAVIRUS (HPV)-16-E6 SENSITIZES CELLS TO ATRACTYLOSIDE-INDUCED APOPTOSIS - ROLE OF P53, ICE-LIKE PROTEASES AND THE MITOCHONDRIAL PERMEABILITY TRANSITION
Journal of cellular biochemistry
THE DNA-BINDING REGULATORY DOMAIN OF P53 - SEE THE C
Pathologie et biologie
STRUCTURES AND FUNCTIONS OF THE TUMOR-SUPPRESSOR P53
Pathologie et biologie
TP53 AND HEPATOCELLULAR-CARCINOMA
Pathologie et biologie