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A superantigen hypothesis for the pathogenesis of chronic hypertrophic rhinosinusitis, allergic fungal sinusitis, and related disorders
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Recurrent nonmenstrual toxic shock syndrome: Clinical manifestations, diagnosis, and treatment
CLINICAL INFECTIOUS DISEASES
Chronic exposure to superantigen induces regulatory CD4(+) T cells with IL-10-mediated suppressive activity
INTERNATIONAL IMMUNOLOGY
In vivo staphylococcal superantigen-driven polyclonal Ig responses in mice: dependence upon CD4(+) cells and human MHC class II
INTERNATIONAL IMMUNOLOGY
Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells
INTERNATIONAL IMMUNOLOGY
Ontogeny of T-helper 1 and T-helper 2 cytokine production in childhood
PEDIATRIC ALLERGY AND IMMUNOLOGY
Toxic shock syndrome toxin-1 accelerated collagen-induced arthritis in mice
JOURNAL OF AUTOIMMUNITY
Peripheral T-Cell tolerance defined through transgenic mouse studies
AUTOIMMUNITY
Superantigen antagonist blocks Th1 cytokine gene induction and lethal shock
JOURNAL OF LEUKOCYTE BIOLOGY
Analysis of the in vivo dendritic cell response to the bacterial superantigen staphylococcal enterotoxin B in the mouse spleen
HISTOLOGY AND HISTOPATHOLOGY
Induction of inflammatory cytokines by extracellular products and LPS of the fish pathogen Aeromonas salmonicida ssp achromogenes in mice and mouse cell cultures
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
Caspase activation during hepatocyte apoptosis induced by tumor necrosis factor-alpha in galactosamine-sensitized mice
LIVER
Bacterial infections and atopic dermatitis
ALLERGY
Toxic shock syndrome and bacterial superantigens: An update
ANNUAL REVIEW OF MICROBIOLOGY
Functional evaluation of HIV/SIV Nef as superantigen
VIROLOGY
Apoptosis of superantigen-activated T cells induced by mycophenolate mofetil treatment
TRANSPLANTATION
Superantigen bacterial toxins: state of the art
TOXICON
Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V-beta domains
JOURNAL OF VIROLOGY
High affinity T cell receptors from yeast display libraries block T cell activation by superantigens
JOURNAL OF MOLECULAR BIOLOGY
Enhanced susceptibility to superantigen-associated streptococcal sepsis inhuman leukocyte antigen-DQ transgenic mice
JOURNAL OF INFECTIOUS DISEASES
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
JOURNAL OF IMMUNOLOGY
Identification of MHC class II-associated peptides that promote the presentation of toxic shock syndrome toxin-1 to T cells
JOURNAL OF IMMUNOLOGY
Cutting edge: The related molecules CD28 and inducible costimulator deliver both unique and complementary signals required for optimal T cell activation
JOURNAL OF IMMUNOLOGY
Possible involvement of reactive oxygen species in D-galactosamine-inducedsensitization against tumor necrosis factor-alpha-induced hepatocyte apoptosis
JOURNAL OF CELLULAR PHYSIOLOGY
Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens
JOURNAL OF BIOLOGICAL CHEMISTRY
Role of T cells and gamma interferon during induction of hypersensitivity to lipopolysaccharide by toxic shock syndrome toxin 1 in mice
INFECTION AND IMMUNITY
Inhibition of bacterial superantigens by peptides and antibodies
INFECTION AND IMMUNITY
Temporal sequence and kinetics of proinflammatory and anti-inflammatory cytokine secretion induced by toxic shock syndrome toxin 1 in human peripheral blood mononuclear cells
INFECTION AND IMMUNITY
Administration of superantigens protects mice from lethal Listeria monocytogenes infection by enhancing cytotoxic T cells
INFECTION AND IMMUNITY
Identity of activation molecule 3 on superantigen-stimulated bovine cells is CD26
INFECTION AND IMMUNITY
The role of leukocyte function-associated antigen-1 in animal models of inflammation
EUROPEAN JOURNAL OF PHARMACOLOGY
Superantigen overcomes resistance of IL-6-deficient mice towards MOG-induced EAE by a TNFR1 controlled pathway
EUROPEAN JOURNAL OF IMMUNOLOGY
Suppression of superantigen-induced lung injury and vasculitis by preadministration of human urinary trypsin inhibitor
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Prevention of murine acute graft-versus-host disease by staphylococcalenterotoxin B treatment
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Roles of I-E molecule and CD28 costimulation in induction of suppression by staphylococcal enterotoxin B in vivo
CELLULAR IMMUNOLOGY
Contrasting patterns of streptococcal superantigen-induced T-cell proliferation in guttate vs. chronic plaque psoriasis
BRITISH JOURNAL OF DERMATOLOGY
Structure-based design of a bispecific receptor mimic that inhibits T cellresponses to a superantigen
BIOCHEMISTRY
Enhanced susceptibility to superantigen-associated streptococcal sepsis inhuman leukocyte antigen-DQ transgenic mice
AMERICAN NATURALIST
Interleukin-10 and apoptotic death at circulating lymphocytes in surgical/anaesthesia trauma
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
Oral tolerance: New approaches, new problems
CLINICAL IMMUNOLOGY
Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation
NATURE MEDICINE
Evidence for superantigen involvement in preeclampsia
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Interleukin 10 (IL-10)-mediated inhibition of inflammatory cytokine production by human alveolar macrophages
CYTOKINE
Superantigen-induced T cell death by apoptosis: Analysis on a single cell level and effect of IFN-gamma and IL-4 treatment
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Invasive group A streptococcal diseases and pyrogenic exotoxins A and B: an update on pathogenesis and management
REVIEWS IN MEDICAL MICROBIOLOGY
Murine gamma-herpesvirus infection causes V(beta)4-specific CDR3-restricted clonal expansions within CD8(+) peripheral blood T lymphocytes
INTERNATIONAL IMMUNOLOGY
Impaired Ca/calcineurin pathway in in vivo anergized CD4 T cells
INTERNATIONAL IMMUNOLOGY
Immune regulation in atonic dermatitis
CURRENT OPINION IN IMMUNOLOGY
Phage-displayed peptides as biosensor reagents
JOURNAL OF MOLECULAR RECOGNITION
Mice transgenic for monocyte-tropic HIV type 1 produce infectious virus and display plasma viremia: A new in vivo system for studying the postintegration phase of HIV replication
AIDS RESEARCH AND HUMAN RETROVIRUSES
Toxic shock syndrome
JOURNAL OF INTENSIVE CARE MEDICINE
Partial T cell activation with an altered superantigenic ligand
IMMUNOLOGY AND CELL BIOLOGY
Exoenzyme S from Pseudomonas aeruginosa induces apoptosis in T lymphocytes
JOURNAL OF LEUKOCYTE BIOLOGY
Apoptosis observed in murine peritoneal macrophages treated with interferon gamma through staphylococcal enterotoxin-dependent cell-mediated cytotoxicity
MICROBIOLOGY AND IMMUNOLOGY
Anti-MAM antibodies in rheumatic disease: Evidence for a MAM-like superantigen in rheumatoid arthritis?
JOURNAL OF RHEUMATOLOGY
Unresponsiveness of intrahepatic lymphocytes to bacterial superantigen: Rapid development of suppressive Mac-1(high) cells in the mouse liver
HEPATOLOGY
Recombinant expression and neutralizing activity of an MHC class II binding epitope of toxic shock syndrome toxin-1
VACCINE
Synergism of Pseudomonas aeruginosa exotoxin A with endotoxin, superantigen, or TNF results in TNFR1-and TNFR2-dependent liver toxicity in mice
IMMUNOLOGY LETTERS
Kinetics of cellular and cytokine responses in a chimeric mouse model for the study of staphylococcal enterotoxin B pathogenesis
IMMUNOLOGY LETTERS
Death the Fas way: regulation and pathophysiology of CD95 and its ligand
PHARMACOLOGY & THERAPEUTICS
Effects of endotoxin-induced fever and probenecid on disposition of enrofloxacin and its metabolite ciprofloxacin after intravascular administration of enrofloxacin in goats
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
A role for CaMKII in T cell memory
CELL
Application of staphylococcal enterotoxin B on normal and atopic skin induces up-regulation of T cells by a superantigen-mediated mechanism
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Coordinate suppression of superantigen-induced cytokine production and T-cell proliferation by a small nonpeptidic inhibitor of class II major histocompatibility complex and CD4 interaction
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Suppressor T cells regulate the nonanergic cell population that remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptorV beta 8.1 transgenic mice
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Development of streptococcal pyrogenic exotoxin C vaccine toxoids that areprotective in the rabbit model of toxic shock syndrome
JOURNAL OF IMMUNOLOGY
Cutting edge: Cell autonomous rather than environmental factors control bacterial superantigen-induced T cell anergy in vivo
JOURNAL OF IMMUNOLOGY
Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-gamma
JOURNAL OF IMMUNOLOGY
Delta-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway
JOURNAL OF IMMUNOLOGY
IL-2 unresponsiveness in anergic CD4(+) T cells is due to defective signaling through the common gamma-chain of the IL-2 receptor
JOURNAL OF IMMUNOLOGY
The multidrug resistance protein 1: A functionally important activation marker for murine Th1 cells
JOURNAL OF IMMUNOLOGY
Nuclear factor of activated T cells transcription factor NFATp controls superantigen-induced lethal shock
JOURNAL OF EXPERIMENTAL MEDICINE
Tumor necrosis factor alpha-mediated toxic shock in Trypanosoma cruzi-infected interleukin 10-deficient mice
INFECTION AND IMMUNITY
Pyrogenic toxin superantigen site specificity in toxic shock syndrome and food poisoning in animals
INFECTION AND IMMUNITY
Modulation of cytokine profiles by the mycoplasma superantigen Mycoplasma arthritidis mitogen parallels susceptibility to arthritis induced by M-arthritidis
INFECTION AND IMMUNITY
CD28, CTLA-4 and their ligands: who does what and to whom?
IMMUNOLOGY
TNF-alpha dependent production of inducible nitric oxide is involved in PGE(1) protection against acute liver injury
GUT
Involvement of kinins, mast cells and sensory neurons in the plasma exudation and paw oedema induced by staphylococcal enterotoxin B in the mouse
EUROPEAN JOURNAL OF PHARMACOLOGY
Evidence for a parapox ovis virus-associated superantigen
EUROPEAN JOURNAL OF IMMUNOLOGY
Automated fiber optic biosensor for multiplexed immunoassays
ENVIRONMENTAL SCIENCE & TECHNOLOGY
Expression of delta opioid receptors by splenocytes from SEB-treated mice and effects on phosphorylation of MAP kinase
CELLULAR IMMUNOLOGY
In vivo staphylococcal enterotoxin B (SEB)-primed murine splenocytes secrete mediators which suppress CD25(hi) expression and cell cycle progression of naive splenocytes in response to SEB in vitro
CELLULAR IMMUNOLOGY
Depression of constitutive murine cytochromes P450 by staphylococcal enterotoxin B
BIOCHEMICAL PHARMACOLOGY
Adenovirus-mediated hepatocyte growth factor gene transfer prevents lethalliver failure in rats
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Importance of Kupffer cells for T-cell-dependent liver injury in mice
AMERICAN JOURNAL OF PATHOLOGY
Proliferation of T lymphocytes from atopic dermatitis skin is enhanced upon anti-CD3, reduced upon mitogen and superantigen, and negligible upon tuberculin stimulation
ACTA DERMATO-VENEREOLOGICA
Superantigens and their association with dermatological inflammatory diseases: Facts and hypotheses
ACTA DERMATO-VENEREOLOGICA
Antigen-induced death of T-lymphocytes
PEDIATRIC PATHOLOGY & MOLECULAR MEDICINE
Superantigens in skin diseases
EUROPEAN JOURNAL OF DERMATOLOGY
Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes
IMMUNITY
Pentoxifylline inhibits superantigen-induced toxic shock and cytokine release
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
Role of T cells in bronchoalveolar space in the development of interstitial pneumonia induced by superantigen in autoimmune-prone mice
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Superantigens and autoimmune disease: are they involved?
CURRENT OPINION IN INFECTIOUS DISEASES
Molecular analysis of the role of streptococcal pyrogenic exotoxin A (SPEA) in invasive soft-tissue infection resulting from Streptococcus pyogenes
MOLECULAR MICROBIOLOGY
T cell subsets in experimental lupus nephritis: modulation by bacterial superantigen
NEPHROLOGY DIALYSIS TRANSPLANTATION
Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells
FASEB JOURNAL
Gram-positive sepsis - Mechanisms and differences from gram-negative sepsis
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
MHC class II-dependent activation of CD4(+) T cell hybridomas by human mast cells through superantigen presentation
JOURNAL OF LEUKOCYTE BIOLOGY
Superantigens augment antigen-specific Th1 responses by inducing IL-12 production in macrophages
JOURNAL OF LEUKOCYTE BIOLOGY
Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
ANNUAL REVIEW OF IMMUNOLOGY