Si mostrano 100 riferimenti a partire da 1 |
Per ulteriori informazioni selezionare i riferimenti di interesse.
Peptoid-peptide hybrids that bind Syk SH2 domains involved in signal transduction
CHEMBIOCHEM
The Wiskott-Aldrich syndrome
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
Solution structure of the PX domain, a target of the SH3 domain
NATURE STRUCTURAL BIOLOGY
SH2 and SH3 domains as targets for anti-proliferative agents
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton
ONCOGENE
Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor
ONCOGENE
Regulation of phospholipase C gamma isoforms in haematopoietic cells - Whyone, not the other?
CELLULAR SIGNALLING
B cell receptor signaling and autoimmunity
FASEB JOURNAL
Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family
GENOMICS
Peptidomimetic SH2 domain antagonists for targeting signal transduction
BIOORGANIC CHEMISTRY OF BIOLOGICAL SIGNAL TRANSDUCTION
Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B byinsulin receptor
MOLECULAR AND CELLULAR BIOCHEMISTRY
A proline-rich protein binds to the localization element of Xenopus Vg1 mRNA and to ligands involved in actin polymerization
EMBO JOURNAL
The ever-expanding Ly49 gene family: repertoire and signaling
IMMUNOLOGICAL REVIEWS
Anti-microbial activity and cell binding are controled by sequence determinants in the anti-microbial peptide PR-39
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module
JOURNAL OF EXPERIMENTAL MEDICINE
WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement
JOURNAL OF CELL SCIENCE
Real time fluorescence imaging of PLC gamma translocation and its interaction with the epidermal growth factor receptor
JOURNAL OF CELL BIOLOGY
Grb4/Nck beta acts as a nuclear repressor of v-Abl-induced transcription from c-jun/c-fos promoter elements
JOURNAL OF BIOLOGICAL CHEMISTRY
SET-related cell division autoantigen-1 (CDA1) arrests cell growth
JOURNAL OF BIOLOGICAL CHEMISTRY
Phage display epitope mapping of human neutrophil flavocytochrome b(558) -Identification of two juxtaposed extracellular domains
JOURNAL OF BIOLOGICAL CHEMISTRY
Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway
JOURNAL OF BIOLOGICAL CHEMISTRY
Fused p47(phox) and p67(phox) truncations efficiently reconstitute NADPH oxidase with higher activity and stability than the individual components
JOURNAL OF BIOLOGICAL CHEMISTRY
A novel superoxide-producing NAD(P)H oxidase in kidney
JOURNAL OF BIOLOGICAL CHEMISTRY
SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor protein thatis developmentally regulated during cardiac myocyte differentiation
JOURNAL OF BIOLOGICAL CHEMISTRY
Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha
EUROPEAN JOURNAL OF IMMUNOLOGY
Serine/threonine phosphorylation of IRS-1 triggers its degradation - Possible regulation by tyrosine phosphorylation
DIABETES
A fusion protein between Rac and p67(phox) (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components
BIOCHEMISTRY
Boundary sequences of the NADPH oxidase p67(phox) C-terminal SH3 domain play on its specificity
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Development of a robust scintillation proximity assay for protein tyrosinephosphatase 1B using the catalytically inactive (C215S) mutant
ANALYTICAL BIOCHEMISTRY
Progress in the development of inhibitors of SH2 domains
CURRENT PHARMACEUTICAL DESIGN
Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering
MOLECULAR BIOLOGY OF THE CELL
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cellsignalling
SEMINARS IN IMMUNOLOGY
Alternative modes of binding of proteins with tandem SH2 domains
PROTEIN SCIENCE
The identification of conserved interactions within the SH3 domain by alignment of sequences and structures
PROTEIN SCIENCE
The isoform-specific stretch of hSos1 defines a new Grb2-binding domain
ONCOGENE
Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signalingand glioblastoma phenotype by Signal-Regulatory Proteins (SIRPs)
ONCOGENE
Roles for the protein tyrosine phosphatase SHP-2 in cytoskeletal organization, cell adhesion and cell migration revealed by overexpression of a dominant negative mutant
ONCOGENE
Solution structure of the human BTK SH3 domain complexed with a proline-rich peptide from p120(cbl)
JOURNAL OF BIOMOLECULAR NMR
The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis
LEUKEMIA
The mutation of insulin receptor substrate-1 gene in Chinese patients withnon-insulin-dependent diabetes mellitus
CHINESE MEDICAL JOURNAL
Novel mutations, no detectable mRNA and familial genetic analysis of the Wiskott-Aldrich syndrome protein gene in six Japanese patients with Wiskott-Aldrich syndrome
EUROPEAN JOURNAL OF PEDIATRICS
Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Suppression of epidermal growth factor-induced phospholipase C activation associated with actin rearrangement in rat hepatocytes in primary culture
HEPATOLOGY
Interaction between PAK and Nck: a template for Nck targets and role of PAK autophosphorylation
MOLECULAR AND CELLULAR BIOLOGY
The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain
EMBO JOURNAL
Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold
EMBO JOURNAL
The SH2 and SH3 adapter Nck: a two-gene family and a linker between tyrosine kinases and multiple signaling networks
HISTOLOGY AND HISTOPATHOLOGY
Signal transduction elements of the B cell antigen receptor and their rolein immunodeficiencies
IMMUNOBIOLOGY
Bradykinin enhances insulin receptor tyrosine kinase in 32D cells reconstituted with bradykinin and insulin signaling pathways
DIABETES RESEARCH AND CLINICAL PRACTICE
Signal transduction via the B-cell antigen receptor: The role of protein tyrosine kinases and protein tyrosine phosphatases
SIGNAL TRANSDUCTION AND THE COORDINATION OF B LYMPHOCYTE DEVELOPMENT AND FUNCTION I
Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons
JOURNAL OF NEUROCHEMISTRY
Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons
JOURNAL OF NEUROCHEMISTRY
R-Ras contains a proline-rich site that binds to SH3 domains and is required for integrin activation by R-Ras
JOURNAL OF BIOLOGICAL CHEMISTRY
Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Arachidonic acid and phosphorylation synergistically induce a conformational change of p47(phox) to activate the phagocyte NADPH oxidase
JOURNAL OF BIOLOGICAL CHEMISTRY
Phosphorylation of a new brain-specific septin, G-septin, by cGMP-dependent protein kinase
JOURNAL OF BIOLOGICAL CHEMISTRY
A novel Pro-Arg motif recognized by WW domains
JOURNAL OF BIOLOGICAL CHEMISTRY
Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules
JOURNAL OF BIOLOGICAL CHEMISTRY
Relationships of p40(phox) withp67(phox) in the activation and expression of the human respiratory burst NADPH oxidase
JOURNAL OF BIOCHEMISTRY
Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites
BLOOD
Determination of the binding specificity of the SH2 domains of protein tyrosine phosphatase SHP-1 through the screening of a combinatorial phosphotyrosyl peptide library
BIOCHEMISTRY
Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma 1
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation
NATURE CELL BIOLOGY
Gene expression of the hematopoietic cell phosphatase in juvenile myelomonocytic leukemia
LEUKEMIA & LYMPHOMA
CRKL binding to BCR-ABL and BCR-ABL transformation
LEUKEMIA & LYMPHOMA
Waltzing with WASP
TRENDS IN CELL BIOLOGY
Insulin signal transduction: possible mechanisms for insulin resistance
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
The next wave: Protein tyrosine phosphatases enter T cell antigen receptorsignalling
CELLULAR SIGNALLING
Insulin signalling: Metabolic pathways and mechanisms for specificity
CELLULAR SIGNALLING
Regulatory role of SH3 domain-mediated protein-protein interactions in synaptic vesicle endocytosis
CELLULAR SIGNALLING
Signaling through gp130: Toward a general scenario of cytokine action
GROWTH FACTORS
Differential modulation of the tyrosine phosphorylation state of the insulin receptor by IRS (insulin receptor subunit) proteins
MOLECULAR ENDOCRINOLOGY
The Wiskott-Aldrich syndrome protein (WASP): Roles in signaling and cytoskeletal organization
ANNUAL REVIEW OF IMMUNOLOGY
The distribution and characterization of SHPS-1, that binds protein tyrosine phosphatase SHP-2, in the human and rat brain
BIOMEDICAL RESEARCH-TOKYO
Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON BIOMEMBRANES
Interaction between Wiskott-Aldrich Syndrome Protein (WASP) and the Fyn protein-tyrosine kinase
MOLECULAR BIOLOGY REPORTS
Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crkand CrkL leads to synergistic activation of c-Jun N-terminal kinase
MOLECULAR AND CELLULAR BIOLOGY
Tyrosine phosphatase SHP-2 dephosphorylates the platelet-derived growth factor receptor but enhances its downstream signalling
BIOCHEMICAL JOURNAL
SHP-1 variant proteins are absent in motheaten mice despite presence of splice variant transcripts with open reading frames
MOLECULAR IMMUNOLOGY
Chemical ligation of folded recombinant proteins: Segmental isotopic labeling of domains for NMR studies
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Brain-derived neurotrophic factor stimulates interactions of Shp2 with phosphatidylinositol 3-kinase and Grb2 in cultured cerebral cortical neurons
JOURNAL OF NEUROCHEMISTRY
Tyrosine phosphorylation and association of BIT with SHP-2 induced by neurotrophins
JOURNAL OF NEUROCHEMISTRY
Cloning and characterization of AASPs: Novel axon-associated SH3 binding-like proteins
JOURNAL OF NEUROBIOLOGY
Ligands for the tyrosine kinase p56(lck) SH2 domain: Discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements
JOURNAL OF MEDICINAL CHEMISTRY
Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein
JOURNAL OF IMMUNOLOGY
Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
JOURNAL OF CLINICAL INVESTIGATION
Dual fatty acylation of p59(Fyn) is required for association with the T cell receptor zeta chain through phosphotyrosine Src homology domain-2 interactions
JOURNAL OF CELL BIOLOGY
Expression of a dominant negative SHP-2 in transgenic mice induces insulinresistance
JOURNAL OF BIOLOGICAL CHEMISTRY
Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase
JOURNAL OF BIOLOGICAL CHEMISTRY
Activation of the phagocyte NADPH oxidase protein p47(phox) - Phosphorylation controls SH3 domain-dependent binding to p22(phox)
JOURNAL OF BIOLOGICAL CHEMISTRY
Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils
JOURNAL OF BIOLOGICAL CHEMISTRY
Mutagenesis of an arginine- and lysine-rich domain in the gp91(phox) subunit of the phagocyte NADPH-oxidase flavocytochrome b(558)
JOURNAL OF BIOLOGICAL CHEMISTRY
Activation of phosphotyrosine phosphatase activity attenuates mitogen-activated protein kinase signaling and inhibits c-FOS and nitric oxide synthaseexpression in macrophages infected with Leishmania donovani
INFECTION AND IMMUNITY
Tyrosine phosphatase SHP-1 is involved in CD66-mediated phagocytosis of Opa(52)-expressing Neisseria gonorrhoeae
INFECTION AND IMMUNITY
Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1
EUROPEAN JOURNAL OF IMMUNOLOGY
Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP
EUROPEAN JOURNAL OF IMMUNOLOGY
Modulation of TCR signaling by beta 1 integrins: role of the tyrosine phosphatase SHP-1
EUROPEAN JOURNAL OF IMMUNOLOGY
Functional analysis of NADPH oxidase in granulocytic cells expressing a Delta 488-497 gp91(phox) deletion mutant
BLOOD