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Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1
JOURNAL OF CELLULAR BIOCHEMISTRY
The CD100-CD72 interaction: a novel mechanism of immune regulation
TRENDS IN IMMUNOLOGY
Signal regulation by family conspiracy
CELLULAR AND MOLECULAR LIFE SCIENCES
Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role of Lyn in the myeloid lineage
IMMUNITY
TGF-beta abrogates TCR-mediated signaling by upregulating tyrosine phosphatases in T cells
SHOCK
Negative regulators of cytokine signaling
INTERNATIONAL JOURNAL OF HEMATOLOGY
Regulation of MAP kinase activity by peptide receptor signalling pathway: Paradigms of multiplicity
CELLULAR SIGNALLING
The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PCCI3 thyroid cell proliferation
MOLECULAR ENDOCRINOLOGY
Biliary glycoprotein (BGPa, CD66a, CEACAM1) mediates inhibitory signals
JOURNAL OF LEUKOCYTE BIOLOGY
Role of adhesion molecules in activation signaling in T lymphocytes
JOURNAL OF CLINICAL IMMUNOLOGY
Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase
HYPERTENSION
SHP-1 expression by malignant small B-cell lymphomas reflects the maturation stage of their normal B-cell counterparts
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
Activating and inhibitory nature of the murine paired immunoglobulin-like receptor family
IMMUNOLOGICAL REVIEWS
Inhibition of natural killer cell activation signals by killer cell immunoglobulin-like receptors (CD158)
IMMUNOLOGICAL REVIEWS
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Methimazole as an antioxidant and immunomodulator in thyroid cells: Mechanisms involving interferon-gamma signaling and H2O2 scavenging
MOLECULAR PHARMACOLOGY
Positive signaling through CD72 induces mitogen-activated protein kinase activation and synergizes with B cell receptor signals to induce X-linked immunodeficiency B cell proliferation
JOURNAL OF IMMUNOLOGY
Genomic structure and transcriptional regulation of the early B cell gene chB1
JOURNAL OF IMMUNOLOGY
The carboxyl terminus of the granulocyte colony- stimulating factor receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of Stat activation
JOURNAL OF IMMUNOLOGY
CD47-signal regulatory protein alpha (SIRP alpha) regulates Fc gamma and complement receptor-mediated phagocytosis
JOURNAL OF EXPERIMENTAL MEDICINE
Inhibition of IgE-mediated mast cell activation by the paired Ig-like receptor PIR-B
JOURNAL OF CLINICAL INVESTIGATION
CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1
JOURNAL OF BIOLOGICAL CHEMISTRY
The SH2 domain containing tyrosine phosphatase-1 down-regulates activationof Lyn and Lyn-induced tyrosine phosphorylation of the CD19 receptor in B cells
JOURNAL OF BIOLOGICAL CHEMISTRY
The CGM1a (CEACAM3/CD66d)-mediated phagocytic pathway of Neisseria gonorrhoeae expressing opacity proteins is also the pathway to cell death
JOURNAL OF BIOLOGICAL CHEMISTRY
Transcriptional activation of mouse sst2 somatostatin receptor promoter bytransforming growth factor-beta - Involvement of Smad4
JOURNAL OF BIOLOGICAL CHEMISTRY
Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis
EUROPEAN JOURNAL OF IMMUNOLOGY
Somatostatin inhibits Akt phosphorylation and cell cycle entry, but not p42/p44 mitogen-activated protein (MAP) kinase activation in normal and tumoral pancreatic acinar cells
ENDOCRINOLOGY
Effect of angiotensin II type 2 receptor on tyrosine kinase Pyk2 and c-JunNH2-terminal kinase via SHP-1 tyrosine phosphatase activity: Evidence fromvascular-targeted transgenic mice of AT2 receptor
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Molecular cloning and characterization of SPAP1, an inhibitory receptor
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Assay of protein tyrosine phosphatases by using matrix-assisted laser desorption ionization time-of-flight mass spectrometry
ANALYTICAL BIOCHEMISTRY
Comparative genome-scale analysis of gene expression profiles in T cell lymphoma cells during malignant progression using a complementary DNA microarray
AMERICAN JOURNAL OF PATHOLOGY
Human inhibitory and activating Ig-like receptors which modulate the function of myeloid cells
MICROBES AND INFECTION
SH2-containing protein tyrosine phosphatase-1 (SHP-1) association with Jak2 in UT-7/Epo cells
BLOOD CELLS MOLECULES AND DISEASES
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: A novel mechanism for regulating B cell signaling
IMMUNITY
The class IV semaphorin CD100 plays nonredundant roles in the immune system: Defective B and T cell activation in CD100-deficient mice
IMMUNITY
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cellsignalling
SEMINARS IN IMMUNOLOGY
Signaling pathways engaged by NK cell receptors: double concerto for activating receptors, inhibitory receptors and NK cells
SEMINARS IN IMMUNOLOGY
Immunoreceptor tyrosine-based inhibitory motifs on activating molecules
CRITICAL REVIEWS IN IMMUNOLOGY
RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemia
HUMAN MOLECULAR GENETICS
Adhesion to target cells is disrupted by the killer cell inhibitory receptor
CURRENT BIOLOGY
Osteoclasts and giant cells: macrophage-macrophage fusion mechanism
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
Negative regulation of B cell receptor-mediated signaling in B-1 cells through CD5 and Ly49 co-receptors via Lyn kinase activity
INTERNATIONAL IMMUNOLOGY
Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta(12,14)-prostaglandin J(2) in the regulation of microglial functions
EUROPEAN JOURNAL OF NEUROSCIENCE
Characterisation of somatostatin sst(2) receptor splice variants
JOURNAL OF PHYSIOLOGY-PARIS
Exploitation of host cell signaling machinery: activation of macrophage phosphotyrosine phosphatases as a novel mechanism of molecular microbial pathogenesis
JOURNAL OF LEUKOCYTE BIOLOGY
Negative regulation of cytokine signaling pathways
ANNUAL REVIEW OF IMMUNOLOGY
Inhibition of ATRA-induced myeloid differentiation in acute promyelocytic leukemia by a new protein tyrosine phosphatase inhibitor, 3,4-dephostatin
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
ets-2 is a target for an Akt (protein kinase B)/Jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice
MOLECULAR AND CELLULAR BIOLOGY
Perinuclear localisation of the protein-tyrosine phosphatase SHP-1 and inhibition of epidermal growth factor-stimulated STAT1/3 activation in A431 cells
EUROPEAN JOURNAL OF CELL BIOLOGY
The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function
IMMUNOLOGY TODAY
Endogenous lectins as cell surface transducers
BIOSCIENCE REPORTS
CD72, a negative regulator of B-cell responsiveness
IMMUNOLOGICAL REVIEWS
Activating and inhibitory signaling in mast cells: New opportunities for therapeutic intervention?
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Negative regulation of Fc epsilon RI signaling by Fc gamma RII costimulation in human blood basophils
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
BCR/ABL inhibition by an escort/phosphatase fusion protein
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Inhibition of growth and metastatic progression of pancreatic carcinoma inhamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Differential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathways
JOURNAL OF NEUROCHEMISTRY
Stimulatory function of gp49A, a murine Ig-like receptor, in rat basophilic leukemia cells
JOURNAL OF IMMUNOLOGY
Cutting edge: NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244)
JOURNAL OF IMMUNOLOGY
Src homology region 2 (SH2) domain-containing phosphatase-1 dephosphorylates B cell linker protein/SH2 domain leukocyte protein of 65 kDa and selectively regulates c-Jun NH2-terminal kinase activation in B cells
JOURNAL OF IMMUNOLOGY
SHPS-1 induces aggregation of Ba/F3 pro-B cells via an interaction with CD47
JOURNAL OF IMMUNOLOGY
Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor alpha-chain
JOURNAL OF IMMUNOLOGY
CD72 negatively regulates signaling through the antigen receptor of B cells
JOURNAL OF IMMUNOLOGY
Transgenic expression of Ly-49A in thymocytes alters repertoire selection
JOURNAL OF IMMUNOLOGY
Cutting edge: Signal-regulatory protein beta 1 is a DAP12-associated activating receptor expressed in myeloid cells
JOURNAL OF IMMUNOLOGY
Cytosolic tyrosine dephosphorylation of STAT5 - Potential role of SHP-2 inSTAT5 regulation
JOURNAL OF BIOLOGICAL CHEMISTRY
Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosisof Neisseria gonorrhoeae
FEBS LETTERS
Peroxovanadium-mediated protection against murine leishmaniasis: role of the modulation of nitric oxide
EUROPEAN JOURNAL OF IMMUNOLOGY
BLNK is associated with the CD72/SHP-1/Grb2 complex in the WEHI231 cell line after membrane IgM cross-linking
EUROPEAN JOURNAL OF IMMUNOLOGY
A porcine cell surface receptor identified by monoclonal antibodies to SWC3 is a member of the signal regulatory protein family and associates with protein-tyrosine phosphatase SHP-1
TISSUE ANTIGENS
The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: Increased resorption and osteopenia in me(v)/me(v) mutant mice
BONE
How to extinguish lymphocyte activation, immunotyrosine-based inhibition motif (ITIM)-bearing molecules a solution?
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation
IMMUNITY
gp49B1 and its related family of counterregulatory receptors of the immunoglobulin superfamily
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages
CURRENT BIOLOGY
Co-receptors on B lymphocytes
CURRENT OPINION IN IMMUNOLOGY
cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function
ONCOGENE
Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1
ONCOGENE
Involvement of SHP-1, a phosphotyrosine phosphatase, during myeloid cell differentiation in acute promyelocytic leukemia cell lines
EUROPEAN JOURNAL OF HAEMATOLOGY
Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis
MOLECULAR ENDOCRINOLOGY
A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells
JOURNAL OF LEUKOCYTE BIOLOGY
Regulation of immune responses through inhibitory receptors
ANNUAL REVIEW OF IMMUNOLOGY
Defective expression of the SHP-1 phosphatase in polycythemia vera
EXPERIMENTAL HEMATOLOGY
Gene structure of mouse BIT/SHPS-1
BIOCHEMICAL JOURNAL
[Difluro(phosphono)methyl]phenylalanine-containing peptide inhibitors of protein tyrosine phosphatases
BIOCHEMICAL JOURNAL
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
EMBO JOURNAL
Negative signaling in health and disease
IMMUNOLOGIC RESEARCH
Antiproliferative and apoptosis-inducing effects of an antitumor glycoprotein from Streptococcus pyogenes
ANTICANCER RESEARCH
Differences in phosphorylation of the IL-2R associated JAK/STAT proteins between HTLV-I (+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma/leukemia
LEUKEMIA RESEARCH
The gp49A gene has extensive sequence conservation with the gp49B gene andprovides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily
IMMUNOGENETICS
New variations of human SHP-1
IMMUNOGENETICS
gp49: An Ig-like receptor with inhibitory properties on mast cells and natural killer cells
IMMUNORECEPTOR TYROSINE-BASED INHIBITION MOTIFS
Paired immunoglobulin-like receptors of activating and inhibitory types
IMMUNORECEPTOR TYROSINE-BASED INHIBITION MOTIFS
Paternal monoallelic expression of the paired immunoglobulin-like receptors PIR-A and PIR-B
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Prominent 85-kDa oligomannosidic glycoproteins of rat brain are signal regulatory proteins and include the SHP substrate-1 for tyrosine phosphatases
JOURNAL OF NEUROCHEMISTRY
Characterization of paired Ig-like receptors in rats
JOURNAL OF IMMUNOLOGY
Structure/function relationship of activating Ly-49D and inhibitory Ly-49G2 NK receptors
JOURNAL OF IMMUNOLOGY
Expression of dominant-negative Src-homology domain 2-containing protein tyrosine phosphatase-1 results in increased Syk tyrosine kinase activity andB cell activation
JOURNAL OF IMMUNOLOGY
Conserved residues amino-terminal of cytoplasmic tyrosines contribute to the SHP-1-mediated inhibitory function of killer cell Ig-like receptors
JOURNAL OF IMMUNOLOGY
Mouse NKR-P1B, a novel NK1.1 antigen with inhibitory function
JOURNAL OF IMMUNOLOGY