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La ricerca find articoli where soggetti phrase all words 'SH2' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 1542 riferimenti
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    1. Kim, HJ; Lee, HH; Yoo, HD; Lee, JH; Hong, ST
      Development of a solid-phase binding assay and identification of nonpeptide ligands for the FynB Src homology 2 domain

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    2. Yang, J; Niu, TQ; Zhang, AH; Mishra, AK; Zhao, ZZJ; Zhou, GW
      Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1

      JOURNAL OF CELLULAR BIOCHEMISTRY
    3. Ijjaali, F; Alcami, M; Mo, O; Yanez, M
      High-level ab initio study of the N+(P-3)+SH2 reactions in the gas phase: Role of spin-forbidden pathways

      INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
    4. Violette, SM; Guan, W; Bartlett, C; Smith, JA; Bardelay, C; Antoine, E; Rickles, RJ; Mandine, E; Van Schravendijk, MR; Adams, SE; Lynch, BA; Shakespeare, WC; Yang, M; Jacobsen, VA; Takeuchi, CS; Macek, KJ; Bohacek, RS; Dalgarno, DC; Weigele, M; Lesuisse, D; Sawyer, TK; Baron, R
      Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption

      BONE
    5. Latour, S; Gish, G; Helgason, CD; Humphries, RK; Pawson, T; Veillette, A
      Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

      NATURE IMMUNOLOGY
    6. Gong, K; Cheng, AM; Akk, AM; Albereola-Ila, J; Gong, GQ; Pawson, T; Chan, AC
      Disruption of T cell signaling networks and development by Grb2 haploid insufficiency

      NATURE IMMUNOLOGY
    7. Ariza, X; Pineda, O; Vilarrasa, J; Shipps, GW; Ma, Y; Dai, XD
      Bocdene and mocdene derivatives of catechols and catecholamines

      ORGANIC LETTERS
    8. Liu, SF; Dockendorff, C; Taylor, SD
      Synthesis of protected L-4-[sulfono(difluoromethyl)]phenylalanine and its incorporation into a peptide

      ORGANIC LETTERS
    9. Lewis, J; Eiben, LJ; Nelson, DL; Cohen, JI; Nichols, KE; Ochs, HD; Notarangelo, LD; Duckett, CS
      Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family

      CLINICAL IMMUNOLOGY
    10. Wang, P; Arabaci, G; Pei, D
      Rapid sequencing of library-derived peptides by partial Edman degradation and mass spectrometry

      JOURNAL OF COMBINATORIAL CHEMISTRY
    11. Cacalano, NA; Sanden, D; Johnston, JA
      Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

      NATURE CELL BIOLOGY
    12. Miao, H; Wei, BR; Peehl, DM; Li, Q; Alexandrou, T; Schelling, JR; Rhim, JS; Sedor, JR; Burnett, E; Wang, BC
      Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

      NATURE CELL BIOLOGY
    13. Ruijtenbeek, R; Kruijtzer, JAW; van de Wiel, W; Fischer, MJE; Fluck, M; Redegeld, FAM; Liskamp, RMJ; Nijkamp, FP
      Peptoid-peptide hybrids that bind Syk SH2 domains involved in signal transduction

      CHEMBIOCHEM
    14. Kile, BT; Alexander, WS
      The suppressors of cytokine signalling (SOCS)

      CELLULAR AND MOLECULAR LIFE SCIENCES
    15. Cant, CA; Ullrich, A
      Signal regulation by family conspiracy

      CELLULAR AND MOLECULAR LIFE SCIENCES
    16. Lung, FDT; Lang, YQ; King, CR; Varady, J; Wu, XW; Wang, S; Roller, PP
      Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain

      JOURNAL OF PEPTIDE RESEARCH
    17. Shakespeare, WC
      SH2 domain inhibition: a problem solved?

      CURRENT OPINION IN CHEMICAL BIOLOGY
    18. Tranter, D
      Phosphinate isosteres of phosphotyrosine for incorporation in Crb2-SH2 inhibitors

      DRUG DISCOVERY TODAY
    19. Sawyer, T; Boyce, B; Dalgarno, D; Iuliucci, J
      Src inhibitors: genomics to therapeutics

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    20. Dowden, J; Ward, SG
      Inhibitors of p56(lck): assessing their potential as tools for manipulating T-lymphocyte activation

      EXPERT OPINION ON THERAPEUTIC PATENTS
    21. Magrangeas, F; Boisteau, O; Denis, S; Jacques, Y; Minvielle, S
      Negative regulation of onconstatin M signaling by suppressor of cytokine signaling (SOCS-3)

      EUROPEAN CYTOKINE NETWORK
    22. Vissel, B; Krupp, JJ; Heinemann, SE; Westbrook, GL
      A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux

      NATURE NEUROSCIENCE
    23. Lu, W; Gong, DQ; Bar-Sagi, D; Cole, PA
      Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling

      MOLECULAR CELL
    24. Ghose, R; Fushman, D; Cowburn, D
      Determination of the rotational diffusion tensor of macromolecules in solution from NMR relaxation data with a combination of exact and approximate methods - Application to the determination of interdomain orientation in multidomain proteins

      JOURNAL OF MAGNETIC RESONANCE
    25. Krebs, DL; Hilton, DJ
      SOCS proteins: Negative regulators of cytokine signaling

      STEM CELLS
    26. Burke, P; Schooler, K; Wiley, HS
      Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

      MOLECULAR BIOLOGY OF THE CELL
    27. Noda, M; Paddock, C; Newman, PJ
      Construction and expression of an enzymatically active form of PECAM-1 containing the phosphatase domain of the protein tyrosine phosphatase, SHP-2

      PROTEIN EXPRESSION AND PURIFICATION
    28. Kameda, H; Risinger, JI; Han, BB; Baek, SJ; Barrett, JC; Glasglow, WC; Eling, TE
      Identification of epidermal growth factor receptor-Grb2-associated Binder-1-SHP-2 complex formation and its functional loss during neoplastic cell progression

      CELL GROWTH & DIFFERENTIATION
    29. Dunican, DJ; Williams, EJ; Howell, FV; Doherty, P
      Selective inhibition of fibroblast growth factor (FGF)-stimulated mitogenesis by a FGF receptor-1-derived phosphopeptide

      CELL GROWTH & DIFFERENTIATION
    30. Bhattacharya, S; Stout, BA; Bates, ME; Bertics, PJ; Malter, JS
      Granulocyte macrophage colony-stimulating factor and interleukin-5 activate STAT5 and induce CIS1 mRNA in human peripheral blood eosinophils

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    31. Vidal, M; Gigoux, V; Garbay, C
      SH2 and SH3 domains as targets for anti-proliferative agents

      CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
    32. Hitchins, MP; Monk, D; Bell, GM; Ali, Z; Preece, MA; Stanier, P; Moore, GE
      Maternal repression of the human GRB10 gene in the developing central nervous system; evaluation of the role for GRB70 in Silver-Russell syndrome

      EUROPEAN JOURNAL OF HUMAN GENETICS
    33. Park, D; Yun, Y
      Tyrosine phosphorylation-dependent yeast two-hybrid system for the identification of the SH2 domain-binding proteins

      MOLECULES AND CELLS
    34. Dan, I; Watanabe, NM; Kusumi, A
      The Ste20 group kinases as regulators of MAP kinase cascades

      TRENDS IN CELL BIOLOGY
    35. Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P
      Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    36. Hofmann, RM; Cotton, GJ; Chang, EJ; Vidal, E; Veach, D; Bornmann, W; Muir, TW
      Fluorescent monitoring of kinase activity in real time: Development of a robust fluorescence-based assay for abi tyrosine kinase activity

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    37. Chen, YT; Onaran, MB; Doss, CJ; Seto, CT
      alpha-Ketocarboxylic acid-based inhibitors of protein tyrosine phosphatases

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    38. Kuusisto, E; Salminen, A; Alafuzoff, I
      Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies

      NEUROREPORT
    39. Leavitt, S; Freire, E
      Direct measurement of protein binding energetics by isothermal titration calorimetry

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    40. Phillips, DR; Prasad, KSS; Manganello, J; Bao, M; Nannizzi-Alaimo, L
      Integrin tyrosine phosphorylation in platelet signaling

      CURRENT OPINION IN CELL BIOLOGY
    41. Dennehy, KM; Ferris, WF; Veenstra, H; Zuckerman, LA; Killeen, N; Beyers, AD
      Determination of the tyrosine phosphorylation sites in the T cell transmembrane glycoprotein CD5

      INTERNATIONAL IMMUNOLOGY
    42. Latour, S; Veillette, A
      Proximal protein tyrosine kinases it immunoreceptor signaling

      CURRENT OPINION IN IMMUNOLOGY
    43. Lewis, CM; Broussard, C; Czar, MJ; Schwartzberg, PL
      Tec kinases: modulators of lymphocyte signaling and development

      CURRENT OPINION IN IMMUNOLOGY
    44. Mandine, E; Gofflo, D; Jean-Baptiste, V; Sarubbi, E; Touyer, G; Deprez, P; Lesuisse, D
      Src homology-2 domain binding assays by scintillation proximity and surface plasmon resonance

      JOURNAL OF MOLECULAR RECOGNITION
    45. Ichaso, N; Dilworth, SM
      Cell transformation by the middle T-antigen of polyoma virus

      ONCOGENE
    46. Han, DC; Shen, TL; Guan, JL
      The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions

      ONCOGENE
    47. Ravichandran, KS
      Signaling via Shc family adapter proteins

      ONCOGENE
    48. Feller, SM
      Crk family adaptors - signalling complex formation and biological roles

      ONCOGENE
    49. Tsygankov, AY; Teckchandani, AM; Feshchenko, EA; Swaminathan, G
      Beyond the RING: CBL proteins as multivalent adapters

      ONCOGENE
    50. Li, W; Fan, JH; Woodley, DT
      Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton

      ONCOGENE
    51. Baisden, JM; Qian, Y; Zot, HM; Flynn, DC
      The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity

      ONCOGENE
    52. Wu, CJ; O'Rourke, DM; Feng, GS; Johnson, GR; Wang, Q; Greene, MI
      The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors

      ONCOGENE
    53. Malabarba, MG; Milia, E; Faretta, M; Zamponi, R; Pelicci, PG; Di Fiore, PP
      A repertoire library that allows the selection of synthetic SH2s with altered binding specificities

      ONCOGENE
    54. Giorgetti-Peraldi, S; Murdaca, J; Mas, JC; Van Obberghen, E
      The adapter protein, Grb10, is a positive regulator of vascular endothelial growth factor signaling

      ONCOGENE
    55. Goodman, PA; Wood, CM; Vassilev, A; Mao, C; Uckun, FM
      Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia

      ONCOGENE
    56. Berry, DM; Benn, SJ; Cheng, AM; McGlade, CJ
      Caspase-dependent cleavage of the hematopoietic specific adaptor protein Gads alters signalling from the T cell receptor

      ONCOGENE
    57. Xue, YZ; Wang, XZ; Li, Z; Gotoh, N; Chapman, D; Skolnik, EY
      Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK)

      DEVELOPMENT
    58. Kile, BT; Nicola, NA; Alexander, WS
      Negative regulators of cytokine signaling

      INTERNATIONAL JOURNAL OF HEMATOLOGY
    59. Hong, EM; Shin, J; Bang, EJ; Kim, MH; Lee, ST; Lee, W
      Letter to the Editor: Complete sequence-specific H-1, C-13 and N-15 resonance assignments of the human PTK6 SH2 domain

      JOURNAL OF BIOMOLECULAR NMR
    60. Pauptit, RA; Dennis, CA; Derbyshire, DJ; Breeze, AL; Weston, SA; Roswell, S; Murshudov, GN
      NMR trial models: experiences with the colicin immunity protein Im7 and the p85 alpha C-terminal SH2-peptide complex

      ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    61. Tamas, P; Solti, Z; Buday, L
      Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor

      CELLULAR SIGNALLING
    62. Oldenhof, J; Ray, A; Vickery, R; Van Tol, HHM
      SH3 ligands in the dopamine D3 receptor

      CELLULAR SIGNALLING
    63. Cailliau, K; Browaeys-Poly, E; Broutin-L'Hermite, I; Nioche, P; Garbay, C; Ducruix, A; Vilain, JP
      Grb2 promotes reinitiation of meiosis in Xenopus oocytes

      CELLULAR SIGNALLING
    64. Poeck, B; Fischer, S; Gunning, D; Zipursky, SL; Salecker, I
      Glial cells mediate target layer selection of retinal axons in the developing visual system of Drosophila

      NEURON
    65. Moniakis, J; Funamoto, S; Fukuzawa, M; Meisenhelder, J; Araki, T; Abe, T; Meili, R; Hunter, T; Williams, J; Firtel, RA
      An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway

      GENES & DEVELOPMENT
    66. Gulli, MP; Peter, M
      Temporal and spatial regulation of Rho-type guanine-nucleotide exchange factors: the yeast perspective

      GENES & DEVELOPMENT
    67. Bruecher-Encke, B; Griffin, JD; Neel, BG; Lorenz, U
      Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation

      LEUKEMIA
    68. Boer, AK; Drayer, AL; Vellenga, E
      Effects of overexpression of the SH2-containing inositol phosphatase SHIP on proliferation and apoptosis of erythroid AS-E2 cells

      LEUKEMIA
    69. Verkhivker, GM; Bouzida, D; Gehlhaar, DK; Rejto, PA; Schaffer, L; Arthurs, S; Colson, AB; Freer, ST; Larson, V; Luty, BA; Marrone, T; Rose, PW
      Hierarchy of simulation models in predicting molecular recognition mechanisms from the binding energy landscapes: Structural analysis of the peptide complexes with SH2 domains

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    70. Hemming, R; Agatep, R; Badiani, K; Wyant, K; Arthur, G; Gietz, RD; Triggs-Raine, B
      Human growth factor receptor bound 14 binds the activated insulin receptorand alters the insulin-stimulated tyrosine phosphorylation levels of multiple proteins

      BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
    71. Palacio, S; Felix, R
      The role of phosphoinositide 3-kinase in spreading osteoclasts induced by colony-stimulating factor-1

      EUROPEAN JOURNAL OF ENDOCRINOLOGY
    72. Greenhalgh, CJ; Hilton, DJ
      Negative regulation of cytokine signaling

      JOURNAL OF LEUKOCYTE BIOLOGY
    73. Nars, M; Vihinen, M
      Coevolution of the domains of cytoplasmic tyrosine kinases

      MOLECULAR BIOLOGY AND EVOLUTION
    74. Morra, M; Howie, D; Grande, MS; Sayos, J; Wang, NH; Wu, CB; Engel, P; Terhorst, C
      X-linked lymphoproliferative disease: A progressive immunodeficiency

      ANNUAL REVIEW OF IMMUNOLOGY
    75. Canonico, B; Felici, C; Papa, S
      CD117

      JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
    76. Davis, MJ; Wu, X; Nurkiewicz, TR; Kawasaki, J; Gui, PC; Hill, MA; Wilson, E
      Regulation of ion channels by protein tyrosine phosphorylation

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    77. Griffin, JD
      Phosphatidyl inositol signaling by BCR/ABL: opportunities for drug development

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    78. Muller, G
      Peptidomimetic SH2 domain antagonists for targeting signal transduction

      BIOORGANIC CHEMISTRY OF BIOLOGICAL SIGNAL TRANSDUCTION
    79. Hemming, K
      Recent developments in the synthesis, chemistry and applications of the fully unsaturated 1,2,4-oxadiazoles

      JOURNAL OF CHEMICAL RESEARCH-S
    80. Mounier, C; Lavoie, L; Dumas, V; Mohammad-Ali, K; Wu, J; Nantel, A; Bergeron, JJM; Thomas, DY; Posner, BI
      Specific inhibition by hGRB10 zeta of insulin-induced glycogen synthase activation: evidence for a novel signaling pathway

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    81. Tauchi, T; Yoshimura, A; Ohyashiki, K
      CIS1, a cytokine-inducible SH2 protein, suppresses BCR/ABL-mediated transformation: Involvement of the ubiquitin proteasome pathway

      EXPERIMENTAL HEMATOLOGY
    82. Siddle, K; Urso, B; Niesler, CA; Cope, DL; Molina, L; Surinya, KH; Soos, MA
      Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

      BIOCHEMICAL SOCIETY TRANSACTIONS
    83. Ahmed, Z; Pillay, TS
      Functional effects of APS and SH2-B on insulin receptor signalling

      BIOCHEMICAL SOCIETY TRANSACTIONS
    84. Pei, L; Teves, RL; Wallace, MC; Gurd, JW
      Transient cerebral ischemia increases tyrosine phosphorylation of the synaptic RAS-GTPase activating protein, SynGAP

      JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
    85. Prasad, N; Topping, RS; Decker, SJ
      SH2-containing inositol 5 '-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading

      MOLECULAR AND CELLULAR BIOLOGY
    86. Hall, C; Michael, GJ; Cann, N; Ferrari, G; Teo, M; Jacobs, T; Monfries, C; Lim, L
      alpha 2-chimaerin, a Cdc42/Rac1 regulator, is selectively expressed in therat embryonic nervous system and is involved in neuritogenesis in N1E-115 neuroblastoma cells

      JOURNAL OF NEUROSCIENCE
    87. Ishii, A; Lo, SH
      A role of tensin in skeletal-muscle regeneration

      BIOCHEMICAL JOURNAL
    88. Paz, PE; Wang, SJ; Clarke, H; Lu, XB; Stokoe, D; Abo, A
      Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

      BIOCHEMICAL JOURNAL
    89. Yu, ZB; Maoui, M; Wu, LT; Banville, D; Shen, SH
      mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain-containing protein tyrosine phosphatases SHP-1 and SHP-2

      BIOCHEMICAL JOURNAL
    90. Nicholson, PR; Empereur, S; Glover, HR; Dilworth, SM
      ShcA tyrosine phosphorylation sites can replace ShcA binding in signallingby middle T-antigen

      EMBO JOURNAL
    91. Takahashi, T; Yamaguchi, S; Chida, K; Shibuya, M
      A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

      EMBO JOURNAL
    92. Lothgren, A; McCartney, M; Thuresson, ER; James, SR
      A model of activation of the protein tyrosine phosphatase SHP-2 by the human leptin receptor

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    93. Kimura, T; Hisano, M; Inoue, Y; Adachi, M
      Tyrosine phosphorylation of the linker for activator of T cells in mast cells by stimulation with the high affinity IgE receptor

      IMMUNOLOGY LETTERS
    94. Rajala, RVS; Anderson, RE
      Interaction of the insulin receptor beta-subunit with phosphatidylinositol3-kinase in bovine ROS

      INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
    95. Duchek, P; Somogyi, K; Jekely, G; Beccari, S; Rorth, P
      Guidance of cell migration by the Drosophila PDGF/VEGF receptor

      CELL
    96. Nollau, P; Mayer, BJ
      Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    97. Yoshida, K; Kufe, D
      Negative regulation of the SHPTP1 protein tyrosine phosphatase by protein kinase c delta in response to DNA damage

      MOLECULAR PHARMACOLOGY
    98. Johnson, RA; Wang, X; Ma, XL; Huong, SM; Huang, ES
      Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signaling

      JOURNAL OF VIROLOGY
    99. Yuan, CH; Yongkiettrakul, S; Byeon, IJL; Zhou, SZ; Tsai, MD
      Solution structures of two FHA1-phosphothreonine peptide complexes provideinsight into the structural basis of the ligand specificity of FHA1 from yeast Rad53

      JOURNAL OF MOLECULAR BIOLOGY
    100. Armon, A; Graur, D; Ben-Tal, N
      ConSurf: An algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information

      JOURNAL OF MOLECULAR BIOLOGY


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Documento generato il 29/10/20 alle ore 17:14:25