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La ricerca find articoli where soggetti phrase all words 'SECRETASE CLEAVAGE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 74 riferimenti
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    1. Yong, VW; Power, C; Forsyth, P; Edwards, DR
      Metalloproteinases in biology and pathology of the nervous system

      NATURE REVIEWS NEUROSCIENCE
    2. Huse, JT; Doms, RW
      Neurotoxic traffic: Uncovering the mechanics of amyloid production in Alzheimer's disease

      TRAFFIC
    3. Chen, M; Fernandez, HL
      Where do Alzheimer's plaques and tangles come from? Aging-induced protein degradation inefficiency

      FRONTIERS IN BIOSCIENCE
    4. Bayer, TA; Wirths, O; Majtenyi, K; Hartmann, T; Multhaup, G; Beyreuther, K; Czech, C
      Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport

      BRAIN PATHOLOGY
    5. Refolo, LM; Pappolla, MA; LaFrancois, J; Malester, B; Schmidt, SD; Thomas-Bryant, T; Tint, GS; Wang, R; Mercken, M; Petanceska, SS; Duff, KE
      A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenicmouse model of Alzheimer's disease

      NEUROBIOLOGY OF DISEASE
    6. Lyons, D; McLoughlin, DM
      Recent advances - Psychiatry

      BRITISH MEDICAL JOURNAL
    7. Wong, PC; Cai, HB; Borchelt, DR; Price, DL
      Genetically engineered models relevant to neurodegenerative disorders - Their value for understanding disease mechanisms and designing/testing experimental therapeutics

      JOURNAL OF MOLECULAR NEUROSCIENCE
    8. Galasko, D
      New approaches to diagnose and treat Alzheimer's disease - A glimpse of the future

      CLINICS IN GERIATRIC MEDICINE
    9. Cataldo, A; Rebeck, GW; Ghetti, B; Hulette, C; Lippa, C; Van Broeckhovan, C; van Duijn, C; Cras, P; Bogdanovic, N; Bird, T; Peterhoff, C; Nixon, R
      Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders

      ANNALS OF NEUROLOGY
    10. Huet, C; Li, ZF; Liu, HZ; Black, RA; Galliano, MF; Engvall, E
      Skeletal muscle cell hypertrophy induced by inhibitors of metalloproteases; myostatin as a potential mediator

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    11. Xu, KP; Zoukhri, D; Zieske, JD; Dartt, DA; Sergheraert, C; Loing, E; Yu, FSX
      A role for MAP kinase in regulating ectodomain shedding of APLP2 in corneal epithelial cells

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    12. Popescu, BO; Cedazo-Minguez, A; Popescu, LM; Winblad, B; Cowburn, RF; Ankarcrona, M
      Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

      JOURNAL OF NEUROSCIENCE RESEARCH
    13. Wiltfang, J; Esselmann, H; Maler, JM; Bleich, S; Huther, G; Kornhuber, J
      Molecular biology of Alzheimer's dementia and its clinical relevance to early diagnosis and new therapeutic strategies

      GERONTOLOGY
    14. Mudher, A; Chapman, S; Richardson, J; Asuni, A; Gibb, G; Pollard, C; Killick, R; Iqbal, T; Raymond, L; Varndell, I; Sheppard, P; Makoff, A; Gower, E; Soden, PE; Lewis, P; Murphy, M; Golde, TE; Rupniak, HT; Anderton, BH; Lovestone, S
      Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase

      JOURNAL OF NEUROSCIENCE
    15. Althoff, K; Mullberg, J; Aasland, D; Voltz, N; Kallen, KJ; Grotzinger, J; Rose-John, S
      Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins

      BIOCHEMICAL JOURNAL
    16. Padovani, A; Borroni, B; Colciaghi, F; Pastorino, L; Archetti, S; Cottini, E; Caimi, L; Cattabeni, F; Di Luca, M
      Platelet amyloid precursor protein forms in AD: a peripheral diagnostic tool and a pharmacological target

      MECHANISMS OF AGEING AND DEVELOPMENT
    17. Hurtado, O; Cardenas, A; Lizasoain, I; Bosca, L; Leza, JC; Lorenzo, P; Moro, MA
      Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices

      NEUROPHARMACOLOGY
    18. Shaw, KTY; Utsuki, T; Rogers, J; Yu, QS; Sambamurti, K; Brossi, A; Ge, YW; Lahiri, DK; Greig, NH
      Phenserine regulates translation of beta-amyloid precursor protein mRNA bya putative interleukin-1 responsive element, a target for drug development

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    19. Wolozin, B
      A fluid connection: Cholesterol and A beta

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    20. Skovronsky, DM; Fath, S; Lee, VMY; Milla, ME
      Neuronal localization of the TNF alpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques

      JOURNAL OF NEUROBIOLOGY
    21. Zhu, GZ; Myles, DG; Primakoff, P
      Testase 1 (ADAM 24) a plasma membrane-anchored sperm protease implicated in sperm function during epididymal maturation or fertilization

      JOURNAL OF CELL SCIENCE
    22. Minopoli, G; de Candia, P; Bonetti, A; Faraonio, R; Zambrano, N; Russo, T
      The beta-amyloid precursor protein functions as a cytosolic anchoring sitethat prevents Fe65 nuclear translocation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    23. Yamazaki, T; Chang, TY; Haass, C; Ihara, Y
      Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-Pick type C cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    24. Kimberly, WT; Zheng, JB; Guenette, SY; Selkoe, DJ
      The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a Notch-like manner

      JOURNAL OF BIOLOGICAL CHEMISTRY
    25. Vincent, B; Paitel, E; Saftig, P; Frobert, Y; Hartmann, D; De Strooper, B; Grassi, J; Lopez-Perez, E; Checler, F
      The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    26. Hussain, I; Christie, G; Schneider, K; Moore, S; Dingwall, C
      Prodomain processing of Asp1 (BACE2) is autocatalytic

      JOURNAL OF BIOLOGICAL CHEMISTRY
    27. Maltese, WA; Wilson, S; Tan, YZ; Suomensaari, S; Sinha, S; Barbour, R; McConlogue, L
      Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide

      JOURNAL OF BIOLOGICAL CHEMISTRY
    28. Skovronsky, DM; Lee, VMY; Pratico, D
      Amyloid precursor protein and amyloid beta peptide in human platelets - Role of cyclooxygenase and protein kinase C

      JOURNAL OF BIOLOGICAL CHEMISTRY
    29. Shirakabe, K; Wakatsuki, S; Kurisaki, T; Fujisawa-Sehara, A
      Roles of meltrin beta/ADAM19 in the processing of neuregulin

      JOURNAL OF BIOLOGICAL CHEMISTRY
    30. Howard, L; Zheng, YF; Horrocks, M; Maciewicz, RA; Blobel, C
      Catalytic activity of ADAM28

      FEBS LETTERS
    31. Koldamova, RP; Lefterov, IM; Lefterova, MI; Lazo, JS
      Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity

      BIOCHEMISTRY
    32. Refolo, LM; Malester, B; LaFrancois, J; Bryant-Thomas, T; Wang, R; Tint, GS; Sambamurti, K; Duff, K; Pappolla, MA
      A high fat, high cholesterol diet accelerates beta-amyloid accumulation inthe CNS of a transgenic mouse model of Alzheimer's disease

      ALZHEIMER'S DISEASE
    33. Steiner, H; Haass, C
      Intramembrane proteolysis by presenilins

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    34. Herz, J; Beffert, U
      Apolipoprotein E receptors: Linking brain development and Alzheimer's disease

      NATURE REVIEWS NEUROSCIENCE
    35. Ledesma, MD; Da Silva, JS; Crassaerts, K; Delacourte, A; De Strooper, B; Dotti, CG
      Brain plasmin enhances APP alpha-cleavage and A beta degradation and is reduced in Alzheimer's disease brains

      EMBO REPORTS
    36. Greenfield, JP; Gross, RS; Gouras, GK; Xu, HX
      Cellular and molecular basis of beta-amyloid precursor protein metabolism

      FRONTIERS IN BIOSCIENCE
    37. Pastorino, L; Colciaghi, F; Marcon, G; Borroni, B; Cottini, E; Cattabeni, F; Padovani, A; Di Luca, M
      Presenilin 2 mutation does not influence expression and concentration of APP forms in human platelets

      MOLECULAR MEDICINE
    38. Austen, BM; Frears, ER; Davies, H
      The use of Seldi ProteinChip (TM) arrays to monitor production of Alzheimer's beta-amyloid in transfected cells

      JOURNAL OF PEPTIDE SCIENCE
    39. Lah, JJ; Levey, AI
      Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments

      MOLECULAR AND CELLULAR NEUROSCIENCE
    40. Karkkainen, I; Rybnikova, E; Pelto-Huikko, M; Huovila, APJ
      Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS

      MOLECULAR AND CELLULAR NEUROSCIENCE
    41. Blasko, I; Veerhuis, R; Stampfer-Kountchev, M; Saurwein-Teissl, M; Eikelenboom, P; Grubeck-Loebenstein, B
      Costimulatory effects of interferon-gamma and interleukin-1 beta or tumor necrosis factor alpha on the synthesis of a beta 1-40 and a beta 1-42 by human astrocytes

      NEUROBIOLOGY OF DISEASE
    42. Refolo, LM; Pappolla, MA; Malester, B; LaFrancois, J; Bryant-Thomas, T; Wang, R; Tint, GS; Sambamurti, K; Duff, K
      Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

      NEUROBIOLOGY OF DISEASE
    43. Weinmaster, G
      Notch signal transduction: a real Rip and more

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    44. Blobel, CP
      Remarkable roles of proteolysis on and beyond the cell surface

      CURRENT OPINION IN CELL BIOLOGY
    45. Annaert, W; De Strooper, B
      Neuronal models to study amyloid precursor protein expression and processing in vitro

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    46. Golde, TE; Eckman, CB; Younkin, SG
      Biochemical detection of A beta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    47. Kopan, R; Goate, A
      A common enzyme connects Notch signaling and Alzheimer's disease

      GENES & DEVELOPMENT
    48. Blusztajn, JK; Berse, B
      The cholinergic neuronal phenotype in Alzheimer's disease

      METABOLIC BRAIN DISEASE
    49. Petanceska, SS; Nagy, V; Frail, D; Gandy, S
      Ovariectomy and 17 beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain

      EXPERIMENTAL GERONTOLOGY
    50. Schlomann, U; Rathke-Hartlieb, S; Yamamoto, S; Jockusch, H; Bartsch, JW
      Tumor necrosis factor a induces a metalloprotease-disintegrin, ADAM8 (CD 156): Implications for neuron-glia interactions during neurodegeneration

      JOURNAL OF NEUROSCIENCE
    51. Seiffert, D; Mitchell, T; Stern, AM; Roach, A; Zhan, YT; Grzanna, R
      Positive-negative epitope-tagging of beta amyloid precursor protein to identify inhibitors of A beta processing

      MOLECULAR BRAIN RESEARCH
    52. Borchardt, T; Schmidt, C; Camakaris, J; Cappai, R; Masters, CL; Beyreuther, K; Multhaup, G
      Differential effects of zinc on amyloid precursor protein (APP) processingin copper-resistant variants of cultured Chinese hamster ovary cells

      CELLULAR AND MOLECULAR BIOLOGY
    53. Petanceska, SS; Nagy, V; Frail, D; Gandy, S
      Ovariectomy and 17 beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain

      NEUROLOGY
    54. Cescato, R; Dumermuth, E; Spiess, M; Paganetti, PA
      Increased generation of alternatively cleaved beta-amyloid peptides in cells expressing mutants of the amyloid precursor protein defective in endocytosis

      JOURNAL OF NEUROCHEMISTRY
    55. De Strooper, B; Annaert, W
      Proteolytic processing and cell biological functions of the amyloid precursor protein

      JOURNAL OF CELL SCIENCE
    56. Chen, FS; Yang, DS; Petanceska, S; Yang, A; Tandon, A; Yu, G; Rozmahel, R; Ghiso, J; Nishimura, M; Zhang, DM; Kawara, T; Levesque, G; Mills, J; Levesque, L; Song, YQ; Rogaeva, E; Westaway, D; Mount, H; Gandy, S; St George-Hyslop, P; Fraser, PE
      Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    57. Zhou, WL; Carpenter, G
      Heregulin-dependent trafficking and cleavage of ErbB-4

      JOURNAL OF BIOLOGICAL CHEMISTRY
    58. Bennett, BD; Babu-Khan, S; Loeloff, R; Louis, JC; Curran, E; Citron, M; Vassar, R
      Expression analysis of BACE2 in brain and peripheral tissues

      JOURNAL OF BIOLOGICAL CHEMISTRY
    59. Gutwein, P; Oleszewski, M; Mechtersheimer, S; Agmon-Levin, N; Krauss, K; Altevogt, P
      Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    60. Doedens, JR; Black, RA
      Stimulation-induced down-regulation of tumor necrosis factor-alpha converting enzyme

      JOURNAL OF BIOLOGICAL CHEMISTRY
    61. Reddy, P; Slack, JL; Davis, R; Cerretti, DP; Kozlosky, CJ; Blanton, RA; Shows, D; Peschon, JJ; Black, RA
      Functional analysis of the domain structure of tumor necrosis factor-alphaconverting enzyme

      JOURNAL OF BIOLOGICAL CHEMISTRY
    62. Galliano, MF; Huet, C; Frygelius, J; Polgren, A; Wewer, UM; Engvall, E
      Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha-actinin-2, is required for myoblast fusion

      JOURNAL OF BIOLOGICAL CHEMISTRY
    63. Di Luca, M; Colciaghi, F; Pastorino, L; Borroni, B; Padovani, A; Cattabeni, F
      Platelets as a peripheral district where to study pathogenetic mechanisms of Alzheimer disease: the case of amyloid precursor protein

      EUROPEAN JOURNAL OF PHARMACOLOGY
    64. Sudoh, S; Hua, G; Kawamura, Y; Maruyama, K; Komano, H; Yanagisawa, K
      Intracellular site of gamma-secretase cleavage for A beta 42 generation inNeuro 2a cells harbouring a presenilin 1 mutation

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    65. Jolly-Tornetta, C; Wolf, BA
      Protein kinase C regulation of intracellular and cell surface amyloid precursor protein (APP) cleavage in CHO695 cells

      BIOCHEMISTRY
    66. Hartmann, T
      Intracellular biology of Alzheimer's disease amyloid beta peptide

      EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
    67. Selkoe, DJ
      Translating cell biology into therapeutic advances in Alzheimer's disease

      NATURE
    68. Wilson, CA; Doms, RW; Lee, VMY
      Intracellular APP processing and A beta production in Alzheimer disease

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    69. Yang, AJ; Chandswangbhuvana, D; Shu, T; Henschen, A; Glabe, CG
      Intracellular accumulation of insoluble, newly synthesized A beta n-42 in amyloid precursor protein-transfected cells that have been treated with A beta 1-42

      JOURNAL OF BIOLOGICAL CHEMISTRY
    70. Selkoe, DJ
      The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

      TRENDS IN CELL BIOLOGY
    71. RUSSO T; FARAONIO R; MINOPOLI G; DECANDIA P; DERENZIS S; ZAMBRANO N
      FE65 AND THE PROTEIN NETWORK CENTERED AROUND THE CYTOSOLIC DOMAIN OF THE ALZHEIMERS BETA-AMYLOID PRECURSOR PROTEIN

      FEBS letters
    72. Xia, WM; Zhang, JM; Ostaszewski, BL; Kimberly, WT; Seubert, P; Koo, EH; Shen, J; Selkoe, DJ
      Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi

      BIOCHEMISTRY
    73. CATALDO AM; BARNETT JL; PIERONI C; NIXON RA
      INCREASED NEURONAL ENDOCYTOSIS AND PROTEASE DELIVERY TO EARLY ENDOSOMES IN SPORADIC ALZHEIMERS-DISEASE - NEUROPATHOLOGIC EVIDENCE FOR A MECHANISM OF INCREASED BETA-AMYLOIDOGENESIS

      The Journal of neuroscience
    74. ELDER GA; TEZAPSIDIS N; CARTER J; SHIOI J; BOURAS C; LI HC; JOHNSTON JM; EFTHIMIOPOULOS S; FRIEDRICH VL; ROBAKIS NK
      IDENTIFICATION AND NEURON-SPECIFIC EXPRESSION OF THE S182 PRESENILIN-I PROTEIN IN HUMAN AND RODENT BRAINS/

      Journal of neuroscience research


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/02/20 alle ore 15:40:03