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Dancing to the tune of chemokines
NATURE IMMUNOLOGY
Fibronectin increases the migration induced by stromal cell-derived factor-1 alpha (SDF-1 alpha) in pre-B acute lymphoblastic leukemia cells
EUROPEAN CYTOKINE NETWORK
Plasma levels of SDF-1 and expression of SDF-1 receptor on CD34(+) cells in mobilized peripheral blood of non-Hodgkin's lymphoma patients
STEM CELLS
Transplantation hematopoiesis
CURRENT OPINION IN HEMATOLOGY
Solution studies of recombinant human stromal-cell-derived factor-1
PROTEIN EXPRESSION AND PURIFICATION
Membrane raft microdomains in chemokine receptor function
SEMINARS IN IMMUNOLOGY
VLA-4-dependent myeloma cell adhesion
LEUKEMIA & LYMPHOMA
SDF-1 induces IL-8 production and transendothelial migration of human cordblood-derived mast cells
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Developmental pattern of expression of the alpha chemokine stromal cell-derived factor 1 in the rat central nervous system
EUROPEAN JOURNAL OF NEUROSCIENCE
SDF-1 alpha induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells
DEVELOPMENT
Loss of chemokine SDF-1 alpha-mediated CXCR4 signalling and receptor internalization in human hepatoma cell line HepG2
CELLULAR SIGNALLING
Fluorescence resonance energy transfer analysis of CCR2-V64I and SDF1-3 ' A polymorphisms: Prevalence in southern Spain HIV type 1(+) cohort and noninfected population
AIDS RESEARCH AND HUMAN RETROVIRUSES
'Reverse gear' cellular movement mediated by chemokines
IMMUNOLOGY AND CELL BIOLOGY
CXCR4 undergoes complex lineage and inducing agent-dependent dissociation of expression and functional responsiveness to SDF-1 alpha during myeloid differentiation
JOURNAL OF LEUKOCYTE BIOLOGY
Chemokine receptors in human basophils: inducible expression of functionalCXCR4
JOURNAL OF LEUKOCYTE BIOLOGY
Cloning, mRNA distribution, and functional expression of an avian counterpart of the chemokine receptor/HIV coreceptor CXCR4
JOURNAL OF LEUKOCYTE BIOLOGY
The role of chemoattraction in cancer metastases
BIOESSAYS
Wanderings of the bone-marrow stem cell
LANCET
Pharmacological properties of peptides derived from stromal cell-derived factor 1: Study on human polymorphonuclear cells
MOLECULAR PHARMACOLOGY
CXCR4 is down-regulated in cells infected with the CD4-independent X4 human immunodeficiency virus type 1 isolate m7NDK
JOURNAL OF VIROLOGY
AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice
JOURNAL OF IMMUNOLOGY
Expression of stromal-derived factor-1 is decreased by IL-1 and TNF and indermal wound healing
JOURNAL OF IMMUNOLOGY
CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells
JOURNAL OF IMMUNOLOGY
A coordinated change in chemokine responsiveness guides plasma cell movements
JOURNAL OF EXPERIMENTAL MEDICINE
Fibroblast-like synoviocytes support B-cell pseudoemperipolesis via a stromal cell-derived factor-1-and CD106 (VCAM-1)-dependent mechanism
JOURNAL OF CLINICAL INVESTIGATION
Reduced expression of stromal-derived factor 1 in autonomous thyroid adenomas and its regulation in thyroid-derived cells
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
Optimal inhibition of X4 HIV isolates by the CXC chemokine stromal cell-derived factor 1 alpha requires interaction with cell surface heparan sulfateproteoglycans
JOURNAL OF BIOLOGICAL CHEMISTRY
Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes
EUROPEAN JOURNAL OF IMMUNOLOGY
Production of stromal cell-derived factor 1 by mesothelial cells and effects of this chemokine on peritoneal B lymphocytes
EUROPEAN JOURNAL OF IMMUNOLOGY
A common stromal cell-derived factor-1 chemokine gene variant is associated with the early onset of type 1 diabetes
DIABETES
Simultaneous signalling through c-mpl, c-kit and CXCR4 enhances the proliferation and differentiation of human megakaryocyte progenitors: possible roles of the PI3-K, PKC and MAPK pathways
BRITISH JOURNAL OF HAEMATOLOGY
Association between the SDF1-3 ' A allele and high levels of CD34(+) progenitor cells mobilized into peripheral blood in humans
BRITISH JOURNAL OF HAEMATOLOGY
Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment
BLOOD
In vitro migratory capacity of CD34(+) cells is related to hematopoietic recovery after autologous stem cell transplantation
BLOOD
Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
BLOOD
Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1
BLOOD
Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice
BLOOD
Mesenchymal precursor cells in the blood of normal individuals
ARTHRITIS RESEARCH
SDF-1-induced activation of ERK enhances HIV-1 expression
EUROPEAN CYTOKINE NETWORK
Crystal structure of recombinant native SDF-1 alpha with additional mutagenesis studies: An attempt at a more comprehensive interpretation of accumulated structure-activity relationship data
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Active movement of T cells away from a chemokine
NATURE MEDICINE
Adhesion molecules involved in transendothelial migration of human hematopoietic progenitor cells
STEM CELLS
The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro
STEM CELLS
Recruitment of primitive peripheral blood cells: Synergism of interleukin 12 with interleukin 6 and stromal cell-derived factor-1
CYTOKINE
Provincial distribution of three HIV-1 resistant polymorphisms (CCR5-Delta32, CCR2-64I, and SDF1-3 ' A) in China
SCIENCE IN CHINA SERIES C-LIFE SCIENCES
Prevalence of CCR2-64I, SDF1-3 ' A and CCR5-Delta 32 alleles in healthy Thais
EUROPEAN JOURNAL OF IMMUNOGENETICS
B cell- and monocyte-activating chemokine (BMAC), a novel non-ELR alpha-chemokine
INTERNATIONAL IMMUNOLOGY
SDF-1 alpha-mediated modulation of synaptic transmission in rat cerebellum
EUROPEAN JOURNAL OF NEUROSCIENCE
Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes
EUROPEAN JOURNAL OF NEUROSCIENCE
CXCR4 on human endothelial cells can serve as both a mediator of biological responses and as a receptor for HIV-2
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Chemokine/receptor dynamics in the regulation of hematopoiesis
INTERNAL MEDICINE
Stromal cells in lymph nodes attract B-lymphoma cells via production of stromal cell-derived factor-1
EUROPEAN JOURNAL OF HAEMATOLOGY
Biological effects of stroma-derived factor-1 alpha on normal and CML CD34(+) haemopoietic cells
LEUKEMIA
Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers
LEUKEMIA
SDF-1 has costimulatory effects on human T cells: Possible involvement of MAPK (ERK2) activation
MICROBIOLOGY AND IMMUNOLOGY
Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells: Possible role in the hematopoietic microenvironment
EXPERIMENTAL HEMATOLOGY
Glucocorticoids preferentially upregulate functional CXCR4 expression in eosinophils
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
SDF-1 activity on microvascular endothelial cells: Consequences on angiogenesis in in vitro and in vivo models
THROMBOSIS RESEARCH
Combination of CCR5 and CXCR4 inhibitors in therapy of human immunodeficiency virus type 1 infection: In vitro studies of mixed virus infections
JOURNAL OF VIROLOGY
CXCR4 receptor expression on human retinal pigment epithelial cells from the blood-retina barrier leads to chemokine secretion and migration in response to stromal cell-derived factor 1 alpha
JOURNAL OF IMMUNOLOGY
Cutting edge: Stromal cell-derived factor-1 is a costimulator for CD4(+) Tcell activation
JOURNAL OF IMMUNOLOGY
Effects of continuous exposure to stromal cell-derived factor-1 alpha on Tcell rolling and tight adhesion to monolayers of activated endothelial cells
JOURNAL OF IMMUNOLOGY
Signal transduction by CXC chemokine receptor 4: Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes
JOURNAL OF EXPERIMENTAL MEDICINE
beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4
JOURNAL OF BIOLOGICAL CHEMISTRY
NMR studies of active N-terminal peptides of stromal cell-derived factor-1- Structural basis for receptor binding
JOURNAL OF BIOLOGICAL CHEMISTRY
CXC chemokine receptor 4 expression and stromal cell-derived factor-1 alpha-induced chemotaxis in CD4(+) T lymphocytes are regulated by interleukin-4andinterleukin-10
IMMUNOLOGY
The CXCR4 agonist ligand stromal derived factor-1 maintains high affinity for receptors in both G(alpha i)-coupled and uncoupled states
EUROPEAN JOURNAL OF PHARMACOLOGY
The chemokine receptor CXCR4 is expressed within the mast cell lineage andits ligand stromal cell-derived factor-1 alpha acts as a mast cell chemotaxin
EUROPEAN JOURNAL OF IMMUNOLOGY
Simplified and rapid assay for detecting the 3 ' A mutation of the SDF-1 gene
CLINICA CHIMICA ACTA
The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques
CIRCULATION RESEARCH
Stroma-derived factor 1 alpha induces a selective inhibition of human erythroid development via the functional upregulation of Fas/CD95 ligand
BRITISH JOURNAL OF HAEMATOLOGY
Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia
BRITISH JOURNAL OF HAEMATOLOGY
The in vitro effects of cytokines on expansion and migration of megakaryocyte progenitors
BRITISH JOURNAL OF HAEMATOLOGY
Impairment of lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing SDF-1-intrakine
BLOOD
Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets
BLOOD
Stromal cell-derived factor-1 (SDF1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)
BLOOD
Solubilization of the chemokine receptor CXCR4
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Cyclic zinc-dithiocarbamate-S,S '-dioxide blocks CXCR4-mediated HIV-1 infection
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Differential effects of stromal derived factor-1 alpha (SDF-1 alpha) on early and late stages of human megakaryocytic development
ANATOMICAL RECORD
Stromal cell-derived factor-1 as a chemoattractant for follicular center lymphoma B cells
JOURNAL OF THE NATIONAL CANCER INSTITUTE
High-performance liquid chromatographic purification and capillary electrophoresis quantification of the chemokine stromal cell-derived factor-1
JOURNAL OF CHROMATOGRAPHY B
The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
IMMUNITY
Distinct biological effects of macrophage inflammatory protein-1 alpha andstroma-derived factor-1 alpha on CD34(+) hemopoietic cells
STEM CELLS
CXCR4 mRNA expression in colon, esophageal and gastric cancers and hepatitis C infected liver
INTERNATIONAL JOURNAL OF ONCOLOGY
TCR-mediated activation of allergen-specific CD45RO(+) memory T lymphocytes results in down-regulation of cell-surface CXCR4 expression and a strongly reduced capacity to migrate in response to stromal cell-derived factor-1
INTERNATIONAL IMMUNOLOGY
The role of cytokine receptor signaling in lymphocyte development
CURRENT OPINION IN IMMUNOLOGY
The chemokine SDF-1 alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
FASEB JOURNAL
Overexpression of the chemokine receptor CXCR4 in B cell chronic lymphocytic leukemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-1)
LEUKEMIA
The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation
JOURNAL OF LEUKOCYTE BIOLOGY
SLC/Exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxisvs. suppression of progenitor proliferation
JOURNAL OF LEUKOCYTE BIOLOGY
Modulation of CXCR4 expression and SDF-1 alpha functional activity during differentiation of human monocytes and macrophages
JOURNAL OF LEUKOCYTE BIOLOGY
Increased migration of cord blood-derived CD34(+) cells, as compared to bone marrow and mobilized peripheral blood CD34(+) cells across uncoated or fibronectin-coated filters
EXPERIMENTAL HEMATOLOGY
The signal sequence trap method
CDNA PREPARATION AND CHARACTERIZATION
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
SCIENCE
Enhanced inhibition of human immunodeficiency virus type 1 by Met-Stromal-Derived Factor 1 beta correlates with down-modulation of CXCR4
JOURNAL OF VIROLOGY
Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1
JOURNAL OF NEUROCHEMISTRY
Identification of two distinct subsets of long-term nonprogressors with divergent viral activity by stromal-derived factor 1 chemokine gene polymorphism analysis
JOURNAL OF INFECTIOUS DISEASES
Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis
JOURNAL OF INFECTIOUS DISEASES
Expression of stromal cell-derived Factor-1/Pre-B cell growth-stimulating factor receptor, CXC chemokine receptor 4, on CD34(+) human bone marrow cells is a phenotypic alteration for committed lymphoid progenitors
JOURNAL OF IMMUNOLOGY